Click here to switch to the map view.

The map label for this gene is flgM

Identifier: 16764528

GI number: 16764528

Start: 1257046

End: 1257339

Strand: Reverse

Name: flgM

Synonym: STM1172

Alternate gene names: 16764528

Gene position: 1257339-1257046 (Counterclockwise)

Preceding gene: 16764529

Following gene: 16764527

Centisome position: 25.88

GC content: 51.7

Gene sequence:

>294_bases
ATGAGCATTGACCGTACCTCACCTTTGAAACCCGTTAGCACTGTCCAGACGCGCGAAACCAGCGACACGCCGGTACAAAA
AACGCGTCAGGAAAAAACGTCCGCCGCGACGAGCGCCAGCGTAACGTTAAGCGACGCGCAAGCGAAGCTCATGCAGCCAG
GCGTCAGCGACATTAATATGGAACGCGTCGAAGCATTAAAAACGGCTATCCGTAACGGTGAGTTAAAAATGGATACGGGA
AAAATAGCAGACTCGCTCATTCGCGAGGCGCAGAGCTACTTACAGAGTAAATAA

Upstream 100 bases:

>100_bases
AACCTATAATTGTGTAAAGATTTTGTCGCGGCTGCCGATGAGATATTCAACCATGATGGTAGCTGGCCGCTACAACGTAA
CCCTCGATGAGGATAAATAA

Downstream 100 bases:

>100_bases
GCGTATGACTCGTTTGTCAGAAATACTTGACCAGATGACCACCGTCCTGAATGACCTGAAGACGGTGATGGACGCCGAGC
AACAACAGCTTTCCGTAGGC

Product: anti-sigma28 factor FlgM

Products: NA

Alternate protein names: Anti-sigma-28 factor

Number of amino acids: Translated: 97; Mature: 96

Protein sequence:

>97_residues
MSIDRTSPLKPVSTVQTRETSDTPVQKTRQEKTSAATSASVTLSDAQAKLMQPGVSDINMERVEALKTAIRNGELKMDTG
KIADSLIREAQSYLQSK

Sequences:

>Translated_97_residues
MSIDRTSPLKPVSTVQTRETSDTPVQKTRQEKTSAATSASVTLSDAQAKLMQPGVSDINMERVEALKTAIRNGELKMDTG
KIADSLIREAQSYLQSK
>Mature_96_residues
SIDRTSPLKPVSTVQTRETSDTPVQKTRQEKTSAATSASVTLSDAQAKLMQPGVSDINMERVEALKTAIRNGELKMDTGK
IADSLIREAQSYLQSK

Specific function: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of

COG id: COG2747

COG function: function code KNU; Negative regulator of flagellin synthesis (anti-sigma28 factor)

Gene ontology:

Cell location: Cytoplasm. Note=After completion of the hook-basal body structure, it is exported out of the cell through the completely assembled hook-basal body structures

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flgM family

Homologues:

Organism=Escherichia coli, GI1787311, Length=97, Percent_Identity=80.4123711340206, Blast_Score=138, Evalue=6e-35,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): FLGM_SALTY (P26477)

Other databases:

- EMBL:   M74222
- EMBL:   U03631
- EMBL:   D25292
- EMBL:   AE006468
- PIR:   A41046
- RefSeq:   NP_460143.1
- DisProt:   DP00027
- PRIDE:   P26477
- GeneID:   1252690
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM1172
- HOGENOM:   HBG648451
- OMA:   MDIGKIA
- ProtClustDB:   PRK10810
- BioCyc:   STYP99287:STM1172-MONOMER
- GO:   GO:0005737
- GO:   GO:0019861
- GO:   GO:0006350
- InterPro:   IPR007412
- TIGRFAMs:   TIGR03824

Pfam domain/function: PF04316 FlgM

EC number: NA

Molecular weight: Translated: 10568; Mature: 10437

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIDRTSPLKPVSTVQTRETSDTPVQKTRQEKTSAATSASVTLSDAQAKLMQPGVSDINM
CCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHHCCCCCCCCH
ERVEALKTAIRNGELKMDTGKIADSLIREAQSYLQSK
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SIDRTSPLKPVSTVQTRETSDTPVQKTRQEKTSAATSASVTLSDAQAKLMQPGVSDINM
CCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHHCCCCCCCCH
ERVEALKTAIRNGELKMDTGKIADSLIREAQSYLQSK
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655712; 8288531; 8200538; 11677609