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The map label for this gene is csgD [H]

Identifier: 16764498

GI number: 16764498

Start: 1229728

End: 1230378

Strand: Reverse

Name: csgD [H]

Synonym: STM1142

Alternate gene names: 16764498

Gene position: 1230378-1229728 (Counterclockwise)

Preceding gene: 16764505

Following gene: 16764497

Centisome position: 25.33

GC content: 40.71

Gene sequence:

>651_bases
ATGTTTAATGAAGTCCATAGTAGTCATGGTCACACACTATTGTTGATCACAAAGCCATCTCTGCAAGCTACGGCATTATT
GCAACATTTAAAGCAATCGCTGGCCATAACCGGAAAACTGCATAATATTCAACGTTCTCTGGAAGATATCTCGGCCGGTT
GCATTGTTTTAATGGATATGATGGAAGCGGATAAGAAGCTTATCCACTATTGGCAGGATAATTTAAGCCGCAAAAACAAT
AATATAAAAACATTATTGTTAAATACCCCTGACGATTATCCCTACCGTGAAATTGAAAACTGGCCTCATATTAACGGCGT
GTTTTACGCTACTGAAGACCAGGAACACGTGGTCAGCGGATTACAGGGTATTCTGCGTGGCGAATGCTATTTTTCACAAA
AATTAGCCAGTTACCTGATTACGCACTCAGGAAATTACCGCTACAACAGCACCGAGTCCGCATTACTCACTCATCGCGAA
AAAGAGATCCTCAATAAGTTACGTATTGGTGCCTCTAATAATGAAATCGCGAGGTCGCTATTTATCAGCGAGAATACGGT
TAAGACACATCTTTATAATCTTTTCAAAAAGATAGCTGTCAAAAATCGCACCCAGGCAGTTTCATGGGCAAACGATAATC
TCAGGCGGTAA

Upstream 100 bases:

>100_bases
ATTTCAACCCACAGCAGTGCAACATCTGTCAGTACTTCTGGTGCCTTTATTTTATGGGGGCAGCTGTCAGATGTGCGATT
AAAAAAAGTGGAGTTTCATC

Downstream 100 bases:

>100_bases
GGCCATGAAACGCTATCTGACCTGGATTGTAGCAGCAGAGTTACTGTTCGCTACCGGAAACCTGCATGCCAATGAAGTTG
AAGTCGAGGTTCCCGGATTG

Product: DNA-binding transcriptional regulator CsgD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MFNEVHSSHGHTLLLITKPSLQATALLQHLKQSLAITGKLHNIQRSLEDISAGCIVLMDMMEADKKLIHYWQDNLSRKNN
NIKTLLLNTPDDYPYREIENWPHINGVFYATEDQEHVVSGLQGILRGECYFSQKLASYLITHSGNYRYNSTESALLTHRE
KEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR

Sequences:

>Translated_216_residues
MFNEVHSSHGHTLLLITKPSLQATALLQHLKQSLAITGKLHNIQRSLEDISAGCIVLMDMMEADKKLIHYWQDNLSRKNN
NIKTLLLNTPDDYPYREIENWPHINGVFYATEDQEHVVSGLQGILRGECYFSQKLASYLITHSGNYRYNSTESALLTHRE
KEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR
>Mature_216_residues
MFNEVHSSHGHTLLLITKPSLQATALLQHLKQSLAITGKLHNIQRSLEDISAGCIVLMDMMEADKKLIHYWQDNLSRKNN
NIKTLLLNTPDDYPYREIENWPHINGVFYATEDQEHVVSGLQGILRGECYFSQKLASYLITHSGNYRYNSTESALLTHRE
KEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR

Specific function: The master regulator for adhesive curli fimbriae expression; necessary for transcription of the csgBAC/ymdA operon. Plays a positive role in biofilm formation. May have the capability to respond to starvation and/or high cell density by activating csgBA t

COG id: COG2771

COG function: function code K; DNA-binding HTH domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH luxR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787277, Length=216, Percent_Identity=92.1296296296296, Blast_Score=417, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016032
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE [H]

EC number: NA

Molecular weight: Translated: 24847; Mature: 24847

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNEVHSSHGHTLLLITKPSLQATALLQHLKQSLAITGKLHNIQRSLEDISAGCIVLMDM
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
MEADKKLIHYWQDNLSRKNNNIKTLLLNTPDDYPYREIENWPHINGVFYATEDQEHVVSG
HHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHCCCCCCCEEEEECCCHHHHHHH
LQGILRGECYFSQKLASYLITHSGNYRYNSTESALLTHREKEILNKLRIGASNNEIARSL
HHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
FISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR
HHCCCHHHHHHHHHHHHHHHCCCHHEEEECCCCCCC
>Mature Secondary Structure
MFNEVHSSHGHTLLLITKPSLQATALLQHLKQSLAITGKLHNIQRSLEDISAGCIVLMDM
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
MEADKKLIHYWQDNLSRKNNNIKTLLLNTPDDYPYREIENWPHINGVFYATEDQEHVVSG
HHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHCCCCCCCEEEEECCCHHHHHHH
LQGILRGECYFSQKLASYLITHSGNYRYNSTESALLTHREKEILNKLRIGASNNEIARSL
HHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
FISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR
HHCCCHHHHHHHHHHHHHHHCCCHHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8817489; 8905232; 9278503 [H]