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The map label for this gene is clpP1 [H]

Identifier: 16764393

GI number: 16764393

Start: 1120666

End: 1122747

Strand: Direct

Name: clpP1 [H]

Synonym: STM1033

Alternate gene names: 16764393

Gene position: 1120666-1122747 (Clockwise)

Preceding gene: 16764392

Following gene: 16764394

Centisome position: 23.07

GC content: 52.5

Gene sequence:

>2082_bases
GTGAAGACAACAGTGGCGGCGATAAAAATGCCGCCGGTGATGACAGCAGGGAACGGACGCGGGGAGGGAAGCAGTAATAG
CTGGTATTCCATCAGGGCTGCAGCCAATAACACGGCGGAAGTCCGCATTTATGACGAGATTGGTGGATGGGGAATTTCGG
CTCGCTGGTTTGCAGAAGAACTGGCTGCACTGGGACAGATTAACCGGATAAATCTGCATATTCATTCACCTGGCGGAGCA
GTACTGGACGGAATAGCCATTTATAACCTCCTGAAAAATCATCCGGCGCAAAAAACGGTGTATATCGATGGAATGGCCTG
CTCAATGGCATCCGCTATTGCGATGGTAGGTAATCCCATCATTATGCCGGAAAACGCCATGATGATGATTCATAAGCCGC
GCGGAGTGGCGGGGGGTGAGGCGGAGGATATCCGGGAATATGCTGACCTGCTTGACAAGATCGAAAGCGTCATTATCCCC
ATCTATACCGAAAAAACTGGAAAAACGCCTGAAGATATTGCTGCCATGCTGGCAAAGGAGACCTGGATGAGCGGCGCGGA
GTGCGTCAGTGAAGGGTTTGCCGACAAACTGATACAGCCTGTAAAAGCAATGGCCTGTATTCATTCAAAACGTGTTGAGG
AGTTTGAGCATATGCCACAGAGCATTAAAGGTATGATTATCGCCCCGCAGGGCAATGCAGGCGCGCAACCGCAGCCACAG
GCAAAAGCCCCTGAGTCACAGATTCAGTCGCAGGCTCAGTCGCTGGTGACTGTAGATGAAAATGCCATTCGCGCACGCCT
GCAGGAAGAACAGCGTAACCGTATCACCGGCATTCAGAATGTGTTTTCACTTTCCGGCGATCGTTATGCCTCGCTGATGG
CAAAGTGCATTGCTGATGTGGATTGCTCTCTGGAAATGGCGAAGGACAGACTGTTGGCCGAGATGGCGAAAGGTATTACG
CCGACTAACCAGCTGAATGGTCCGCAGAATCGCGCAGAGTTTCATGCCGGGATGTATACCGGAAACGGTAATATTACCGG
CGACGCCGTTCGCGCTGCCGTGATGGCCCGCGCAGGCTATGAAGAAGCGCAGAAGGATAACCCGTACAACTGTATGACCC
TGCGTGAACTGGCGCGAATTTCGCTGGTGGCGAGGGGTACAGGCGTGTCCAGCATGAATCCCATGCAGATGATCGGCATG
GCATTTACGCACAGCACCTCCGATTTCGGTAACATTCTGCTGGATGTTGCAAACAAGTCCATTCTGCAGGGCTGGCAGGA
AGCGCCGGAAACCTTCGATGCCTGGACCAAAAAAGGACAGTTGTCTGATTTCAGGATTGCGCACCGTGTGGGTATGGGGG
GATTCAGTTCACTGCGTCAGGTTCGTGAAGGAGCGGAATACAAATACGTCACCACAGGGGATAAACAGGCGACCATTGCG
CTCGCTACCTATGGGGAGCTGTTCAGCATTACCCGCCAGGCCATCATCAATGATGATATGAATATGCTGACGGATGTCCC
GATGAAGCTGGGACGTGCGGCAAAAGCCACCATTGCCGATCTGGTTTATGACGTTCTCATCAGTAACCAGAAACTGTCCA
GTGATAATGTGGCGCTGTTTGACAAGACGAAACACGCAAACGTCCTTGAAAAAGCCGTTATGGATGTGGCGTCCCTGGAT
AAAGCGCGCCAGCTAATGCGGATGCAGAAAGAGGGCGATCGCCACCTCAATATCCGTCCGGCATTTGTACTGGTGCCGAC
GGCGATGGAGTCTGTTTCAAATCAGGTGATTAAATCTGTCAGTGTCAAGGGGGCGGATATTAACGCCGGGATCATTAACC
CGGTGAAAGATTTCGCCACGGTGATCGCGGAGCCTCGTCTTGATGACGCCAGTCAGTCCACTTTCTATCTTACTGCAGCA
AAAGGCAGCGATACCGTTGAGGTGGCTTACCTTAACGGCGTGGATGAGCCGTATATCGACCAGCAGGAAGGATTCACGGT
GGATGGCGTAACCACGAAAGTTCGTATTGATGCGGGCGTTGCGCCGGTGGATTATCGCGGCATGGTGAAATGCACCGTAT
AA

Upstream 100 bases:

>100_bases
AAACGCCGCCGTAAGGCGGAAATTGACGAAAACCGTAAGCTGGGACTGGTATTTGATACTGATCCGGCACATGACCCGGG
GGAACAGGATAATGCCGGAA

Downstream 100 bases:

>100_bases
CCCACTAAAAGCAGACATTAAGCGATACGGCCCTGACGGGCTTTTTTTATACCTGAAATCCGGCACGGCGTGCCGGAAAG
GAGAATAACCGTGGCTAAGA

Product: Clp protease-like protein

Products: NA

Alternate protein names: Endopeptidase Clp 1 [H]

Number of amino acids: Translated: 693; Mature: 693

Protein sequence:

>693_residues
MKTTVAAIKMPPVMTAGNGRGEGSSNSWYSIRAAANNTAEVRIYDEIGGWGISARWFAEELAALGQINRINLHIHSPGGA
VLDGIAIYNLLKNHPAQKTVYIDGMACSMASAIAMVGNPIIMPENAMMMIHKPRGVAGGEAEDIREYADLLDKIESVIIP
IYTEKTGKTPEDIAAMLAKETWMSGAECVSEGFADKLIQPVKAMACIHSKRVEEFEHMPQSIKGMIIAPQGNAGAQPQPQ
AKAPESQIQSQAQSLVTVDENAIRARLQEEQRNRITGIQNVFSLSGDRYASLMAKCIADVDCSLEMAKDRLLAEMAKGIT
PTNQLNGPQNRAEFHAGMYTGNGNITGDAVRAAVMARAGYEEAQKDNPYNCMTLRELARISLVARGTGVSSMNPMQMIGM
AFTHSTSDFGNILLDVANKSILQGWQEAPETFDAWTKKGQLSDFRIAHRVGMGGFSSLRQVREGAEYKYVTTGDKQATIA
LATYGELFSITRQAIINDDMNMLTDVPMKLGRAAKATIADLVYDVLISNQKLSSDNVALFDKTKHANVLEKAVMDVASLD
KARQLMRMQKEGDRHLNIRPAFVLVPTAMESVSNQVIKSVSVKGADINAGIINPVKDFATVIAEPRLDDASQSTFYLTAA
KGSDTVEVAYLNGVDEPYIDQQEGFTVDGVTTKVRIDAGVAPVDYRGMVKCTV

Sequences:

>Translated_693_residues
MKTTVAAIKMPPVMTAGNGRGEGSSNSWYSIRAAANNTAEVRIYDEIGGWGISARWFAEELAALGQINRINLHIHSPGGA
VLDGIAIYNLLKNHPAQKTVYIDGMACSMASAIAMVGNPIIMPENAMMMIHKPRGVAGGEAEDIREYADLLDKIESVIIP
IYTEKTGKTPEDIAAMLAKETWMSGAECVSEGFADKLIQPVKAMACIHSKRVEEFEHMPQSIKGMIIAPQGNAGAQPQPQ
AKAPESQIQSQAQSLVTVDENAIRARLQEEQRNRITGIQNVFSLSGDRYASLMAKCIADVDCSLEMAKDRLLAEMAKGIT
PTNQLNGPQNRAEFHAGMYTGNGNITGDAVRAAVMARAGYEEAQKDNPYNCMTLRELARISLVARGTGVSSMNPMQMIGM
AFTHSTSDFGNILLDVANKSILQGWQEAPETFDAWTKKGQLSDFRIAHRVGMGGFSSLRQVREGAEYKYVTTGDKQATIA
LATYGELFSITRQAIINDDMNMLTDVPMKLGRAAKATIADLVYDVLISNQKLSSDNVALFDKTKHANVLEKAVMDVASLD
KARQLMRMQKEGDRHLNIRPAFVLVPTAMESVSNQVIKSVSVKGADINAGIINPVKDFATVIAEPRLDDASQSTFYLTAA
KGSDTVEVAYLNGVDEPYIDQQEGFTVDGVTTKVRIDAGVAPVDYRGMVKCTV
>Mature_693_residues
MKTTVAAIKMPPVMTAGNGRGEGSSNSWYSIRAAANNTAEVRIYDEIGGWGISARWFAEELAALGQINRINLHIHSPGGA
VLDGIAIYNLLKNHPAQKTVYIDGMACSMASAIAMVGNPIIMPENAMMMIHKPRGVAGGEAEDIREYADLLDKIESVIIP
IYTEKTGKTPEDIAAMLAKETWMSGAECVSEGFADKLIQPVKAMACIHSKRVEEFEHMPQSIKGMIIAPQGNAGAQPQPQ
AKAPESQIQSQAQSLVTVDENAIRARLQEEQRNRITGIQNVFSLSGDRYASLMAKCIADVDCSLEMAKDRLLAEMAKGIT
PTNQLNGPQNRAEFHAGMYTGNGNITGDAVRAAVMARAGYEEAQKDNPYNCMTLRELARISLVARGTGVSSMNPMQMIGM
AFTHSTSDFGNILLDVANKSILQGWQEAPETFDAWTKKGQLSDFRIAHRVGMGGFSSLRQVREGAEYKYVTTGDKQATIA
LATYGELFSITRQAIINDDMNMLTDVPMKLGRAAKATIADLVYDVLISNQKLSSDNVALFDKTKHANVLEKAVMDVASLD
KARQLMRMQKEGDRHLNIRPAFVLVPTAMESVSNQVIKSVSVKGADINAGIINPVKDFATVIAEPRLDDASQSTFYLTAA
KGSDTVEVAYLNGVDEPYIDQQEGFTVDGVTTKVRIDAGVAPVDYRGMVKCTV

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=202, Percent_Identity=27.7227722772277, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538017, Length=131, Percent_Identity=30.5343511450382, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI20129427, Length=200, Percent_Identity=28, Blast_Score=76, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 75188; Mature: 75188

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTVAAIKMPPVMTAGNGRGEGSSNSWYSIRAAANNTAEVRIYDEIGGWGISARWFAEE
CCCEEEEEECCCEEECCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHH
LAALGQINRINLHIHSPGGAVLDGIAIYNLLKNHPAQKTVYIDGMACSMASAIAMVGNPI
HHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCE
IMPENAMMMIHKPRGVAGGEAEDIREYADLLDKIESVIIPIYTEKTGKTPEDIAAMLAKE
EECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHH
TWMSGAECVSEGFADKLIQPVKAMACIHSKRVEEFEHMPQSIKGMIIAPQGNAGAQPQPQ
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEEEECCCCCCCCCCC
AKAPESQIQSQAQSLVTVDENAIRARLQEEQRNRITGIQNVFSLSGDRYASLMAKCIADV
CCCCHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
DCSLEMAKDRLLAEMAKGITPTNQLNGPQNRAEFHAGMYTGNGNITGDAVRAAVMARAGY
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCEEEECCCCCCHHHHHHHHHHHCCC
EEAQKDNPYNCMTLRELARISLVARGTGVSSMNPMQMIGMAFTHSTSDFGNILLDVANKS
HHHHCCCCCCHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
ILQGWQEAPETFDAWTKKGQLSDFRIAHRVGMGGFSSLRQVREGAEYKYVTTGDKQATIA
HHHHHHHCHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCCEEEE
LATYGELFSITRQAIINDDMNMLTDVPMKLGRAAKATIADLVYDVLISNQKLSSDNVALF
EEEHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCEEEE
DKTKHANVLEKAVMDVASLDKARQLMRMQKEGDRHLNIRPAFVLVPTAMESVSNQVIKSV
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEEECHHHHHHHHHHHHHH
SVKGADINAGIINPVKDFATVIAEPRLDDASQSTFYLTAAKGSDTVEVAYLNGVDEPYID
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCC
QQEGFTVDGVTTKVRIDAGVAPVDYRGMVKCTV
CCCCEEECCCEEEEEEECCCCCCCCCCEEEEEC
>Mature Secondary Structure
MKTTVAAIKMPPVMTAGNGRGEGSSNSWYSIRAAANNTAEVRIYDEIGGWGISARWFAEE
CCCEEEEEECCCEEECCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHH
LAALGQINRINLHIHSPGGAVLDGIAIYNLLKNHPAQKTVYIDGMACSMASAIAMVGNPI
HHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCE
IMPENAMMMIHKPRGVAGGEAEDIREYADLLDKIESVIIPIYTEKTGKTPEDIAAMLAKE
EECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHH
TWMSGAECVSEGFADKLIQPVKAMACIHSKRVEEFEHMPQSIKGMIIAPQGNAGAQPQPQ
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEEEECCCCCCCCCCC
AKAPESQIQSQAQSLVTVDENAIRARLQEEQRNRITGIQNVFSLSGDRYASLMAKCIADV
CCCCHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
DCSLEMAKDRLLAEMAKGITPTNQLNGPQNRAEFHAGMYTGNGNITGDAVRAAVMARAGY
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCEEEECCCCCCHHHHHHHHHHHCCC
EEAQKDNPYNCMTLRELARISLVARGTGVSSMNPMQMIGMAFTHSTSDFGNILLDVANKS
HHHHCCCCCCHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
ILQGWQEAPETFDAWTKKGQLSDFRIAHRVGMGGFSSLRQVREGAEYKYVTTGDKQATIA
HHHHHHHCHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCCEEEE
LATYGELFSITRQAIINDDMNMLTDVPMKLGRAAKATIADLVYDVLISNQKLSSDNVALF
EEEHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCEEEE
DKTKHANVLEKAVMDVASLDKARQLMRMQKEGDRHLNIRPAFVLVPTAMESVSNQVIKSV
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEEECHHHHHHHHHHHHHH
SVKGADINAGIINPVKDFATVIAEPRLDDASQSTFYLTAAKGSDTVEVAYLNGVDEPYID
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCC
QQEGFTVDGVTTKVRIDAGVAPVDYRGMVKCTV
CCCCEEECCCEEEEEEECCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]