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The map label for this gene is dpaL

Identifier: 16764362

GI number: 16764362

Start: 1093858

End: 1095072

Strand: Direct

Name: dpaL

Synonym: STM1002

Alternate gene names: 16764362

Gene position: 1093858-1095072 (Clockwise)

Preceding gene: 16764357

Following gene: 16764363

Centisome position: 22.52

GC content: 45.6

Gene sequence:

>1215_bases
ATGCATGAGCTTATTAAATATCAGTTTAATACACGTCGGAAAAAATATGGTACAGGAGCGGCCTTAAGTTTGCTTAACGG
AAATGTTGGGCATGAGGTGTTAGCATTTCATAAAAAATTACCCAATTATGCCGTCACGCCGTTACATAATCTGGCGCATC
TAAGCCAGCGGCTTGGACTAGGGTCCATCCATATTAAAGATGAGTCCTGGCGTTTTGGCCTGAATGCTTTTAAAGGTCTG
GGCGGCTCTTATGCTGTAGGAAAATATCTCGCTGATAAATTGCAATGTGATATTAACTCGTTAAGTTTTGCTGCCCTTAA
TACTCCTGAGATTAAAGAAAAAATTAAAGATTGTGTTTTTGTTACCGCGACGGATGGCAATCATGGCCGTGGTGTGGCGT
GGGCGGCAGAGCAATTAGGTCTAAAAGCCGTCGTTTATATGCCTAAAGGATCATCGTTAATCCGGGCAGAGAATATTCGC
CATCATGGAGCTGAATGCACCATCACCGATCTGAACTACGATGATGCAGTGCGACTGGCCCATAGAATGGCGCAAACAAA
AGGCTGGGTGCTTTTGCAGGATACAGCCTGGACAGGGTATGAAGAGATCCCAACATGGATTATGCAAGGCTATATGACAC
TAGCGGTTGAAGCTTATGAGCAGCTCGCAGAAACAAACAGTCCGTTGCCAACCCATCTTATTTTACAAGCGGGGGTGGGA
TCGTTTGCTGGCAGTGTTATGGGTTATTTTGTTGAAAAAATGCAGGAAAATATCCCTAATATTATTGTGGTTGAGCCGCA
TCAGGCCAACTGTCTTTATCAATCCGCAGTTATGGATGATGGTCAACCTCACTGCGTCACTGGCGATATGGCGACGATAA
TGGCCGGGCTTGCGTGTGGGGAGCCGAATATTATCAGTTGGCCTATTATTCGGGACAACACCAGTTGTTTTATTTCCGCT
GATGACTGTCTGGCGGCTAAGGGTATGCGTATTTCTGCCGCGCCGCGTCCAGGTACGGATACGCCTTTTATTTCCGGCGA
GTCCGGAGCTATTGGCGTAGGGTTACTTTATGAGTTGATGAACAATATGCATTATCAGGATCTTGCTAATCGCTTACAGC
TTGATGCCAGTGCTCATGTTCTGCTTATTAGCACCGAAGGTGATACGTCCCCAGATATTTATGAAGATATAGTCTGGAAC
GGACGCAGTGCTTAA

Upstream 100 bases:

>100_bases
ACTACTACAGCCACAAAACGCGAGTTCTTTGCTTGTTTCTACTCAATAATTGACAAAAATATATTATTTCAATAAATAAA
CTTTAACAAAAGGTATCATT

Downstream 100 bases:

>100_bases
ACATTACGACTAAAAAATTAGATAATAAAGGTAGCATGTAAAAATGCGTTTTTTATACGCATAATAAACCTAATGCAGGA
AGCAAGACTTTATAACAATA

Product: diaminopropionate ammonia-lyase

Products: NA

Alternate protein names: Diaminopropionatase; Alpha,beta-diaminopropionate ammonia-lyase

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MHELIKYQFNTRRKKYGTGAALSLLNGNVGHEVLAFHKKLPNYAVTPLHNLAHLSQRLGLGSIHIKDESWRFGLNAFKGL
GGSYAVGKYLADKLQCDINSLSFAALNTPEIKEKIKDCVFVTATDGNHGRGVAWAAEQLGLKAVVYMPKGSSLIRAENIR
HHGAECTITDLNYDDAVRLAHRMAQTKGWVLLQDTAWTGYEEIPTWIMQGYMTLAVEAYEQLAETNSPLPTHLILQAGVG
SFAGSVMGYFVEKMQENIPNIIVVEPHQANCLYQSAVMDDGQPHCVTGDMATIMAGLACGEPNIISWPIIRDNTSCFISA
DDCLAAKGMRISAAPRPGTDTPFISGESGAIGVGLLYELMNNMHYQDLANRLQLDASAHVLLISTEGDTSPDIYEDIVWN
GRSA

Sequences:

>Translated_404_residues
MHELIKYQFNTRRKKYGTGAALSLLNGNVGHEVLAFHKKLPNYAVTPLHNLAHLSQRLGLGSIHIKDESWRFGLNAFKGL
GGSYAVGKYLADKLQCDINSLSFAALNTPEIKEKIKDCVFVTATDGNHGRGVAWAAEQLGLKAVVYMPKGSSLIRAENIR
HHGAECTITDLNYDDAVRLAHRMAQTKGWVLLQDTAWTGYEEIPTWIMQGYMTLAVEAYEQLAETNSPLPTHLILQAGVG
SFAGSVMGYFVEKMQENIPNIIVVEPHQANCLYQSAVMDDGQPHCVTGDMATIMAGLACGEPNIISWPIIRDNTSCFISA
DDCLAAKGMRISAAPRPGTDTPFISGESGAIGVGLLYELMNNMHYQDLANRLQLDASAHVLLISTEGDTSPDIYEDIVWN
GRSA
>Mature_404_residues
MHELIKYQFNTRRKKYGTGAALSLLNGNVGHEVLAFHKKLPNYAVTPLHNLAHLSQRLGLGSIHIKDESWRFGLNAFKGL
GGSYAVGKYLADKLQCDINSLSFAALNTPEIKEKIKDCVFVTATDGNHGRGVAWAAEQLGLKAVVYMPKGSSLIRAENIR
HHGAECTITDLNYDDAVRLAHRMAQTKGWVLLQDTAWTGYEEIPTWIMQGYMTLAVEAYEQLAETNSPLPTHLILQAGVG
SFAGSVMGYFVEKMQENIPNIIVVEPHQANCLYQSAVMDDGQPHCVTGDMATIMAGLACGEPNIISWPIIRDNTSCFISA
DDCLAAKGMRISAAPRPGTDTPFISGESGAIGVGLLYELMNNMHYQDLANRLQLDASAHVLLISTEGDTSPDIYEDIVWN
GRSA

Specific function: Catalyzes the alpha,beta-elimination reaction of both L- and D-alpha,beta-diaminopropionate, the most suitable substrates to form pyruvate and ammonia. The L- and D-isomers of serine are also degraded, though slowly; it is the only serine dehydratase whic

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789235, Length=390, Percent_Identity=50.5128205128205, Blast_Score=364, Evalue=1e-102,
Organism=Escherichia coli, GI1790207, Length=239, Percent_Identity=27.6150627615063, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPAL_SALTY (P40817)

Other databases:

- EMBL:   AE006468
- RefSeq:   NP_459977.1
- ProteinModelPortal:   P40817
- GeneID:   1252520
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM1002
- HOGENOM:   HBG738666
- OMA:   DGNHGRS
- ProtClustDB:   PRK08206
- BioCyc:   STYP99287:STM1002-MONOMER
- BRENDA:   4.3.1.15
- InterPro:   IPR010081
- InterPro:   IPR019871
- InterPro:   IPR001926
- TIGRFAMs:   TIGR03528
- TIGRFAMs:   TIGR01747

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.3.1.15

Molecular weight: Translated: 44153; Mature: 44153

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHELIKYQFNTRRKKYGTGAALSLLNGNVGHEVLAFHKKLPNYAVTPLHNLAHLSQRLGL
CCCHHHHHHHCCHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
GSIHIKDESWRFGLNAFKGLGGSYAVGKYLADKLQCDINSLSFAALNTPEIKEKIKDCVF
CEEEEECCCCEECCHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCEEE
VTATDGNHGRGVAWAAEQLGLKAVVYMPKGSSLIRAENIRHHGAECTITDLNYDDAVRLA
EEECCCCCCCCEEEHHHHCCCEEEEEECCCCCEEEEHHHHHCCCEEEEEECCCHHHHHHH
HRMAQTKGWVLLQDTAWTGYEEIPTWIMQGYMTLAVEAYEQLAETNSPLPTHLILQAGVG
HHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEECCCH
SFAGSVMGYFVEKMQENIPNIIVVEPHQANCLYQSAVMDDGQPHCVTGDMATIMAGLACG
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHCCCCCCCEECCCHHHHHHHHHCC
EPNIISWPIIRDNTSCFISADDCLAAKGMRISAAPRPGTDTPFISGESGAIGVGLLYELM
CCCEEEEEEEECCCEEEEECCHHHHHCCCEEECCCCCCCCCCEECCCCCCCHHHHHHHHH
NNMHYQDLANRLQLDASAHVLLISTEGDTSPDIYEDIVWNGRSA
HCCCHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHCCCCCC
>Mature Secondary Structure
MHELIKYQFNTRRKKYGTGAALSLLNGNVGHEVLAFHKKLPNYAVTPLHNLAHLSQRLGL
CCCHHHHHHHCCHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
GSIHIKDESWRFGLNAFKGLGGSYAVGKYLADKLQCDINSLSFAALNTPEIKEKIKDCVF
CEEEEECCCCEECCHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCEEE
VTATDGNHGRGVAWAAEQLGLKAVVYMPKGSSLIRAENIRHHGAECTITDLNYDDAVRLA
EEECCCCCCCCEEEHHHHCCCEEEEEECCCCCEEEEHHHHHCCCEEEEEECCCHHHHHHH
HRMAQTKGWVLLQDTAWTGYEEIPTWIMQGYMTLAVEAYEQLAETNSPLPTHLILQAGVG
HHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEECCCH
SFAGSVMGYFVEKMQENIPNIIVVEPHQANCLYQSAVMDDGQPHCVTGDMATIMAGLACG
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHCCCCCCCEECCCHHHHHHHHHCC
EPNIISWPIIRDNTSCFISADDCLAAKGMRISAAPRPGTDTPFISGESGAIGVGLLYELM
CCCEEEEEEEECCCEEEEECCHHHHHCCCEEECCCCCCCCCCEECCCCCCCHHHHHHHHH
NNMHYQDLANRLQLDASAHVLLISTEGDTSPDIYEDIVWNGRSA
HCCCHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677609; 3275662