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The map label for this gene is aroA [H]

Identifier: 16764338

GI number: 16764338

Start: 1062634

End: 1063917

Strand: Direct

Name: aroA [H]

Synonym: STM0978

Alternate gene names: 16764338

Gene position: 1062634-1063917 (Clockwise)

Preceding gene: 16764337

Following gene: 16764339

Centisome position: 21.88

GC content: 53.89

Gene sequence:

>1284_bases
ATGGAATCCCTGACGTTACAACCCATCGCGCGGGTCGATGGCGCCATTAATTTACCTGGCTCCAAAAGTGTTTCAAACCG
TGCTTTGCTCCTGGCGGCTTTAGCTTGTGGTAAAACCGCTCTGACGAATCTGCTGGATAGCGATGACGTCCGCCATATGC
TCAATGCCCTGAGCGCGTTGGGGATCAATTACACCCTTTCTGCCGATCGCACCCGCTGTGATATCACGGGTAATGGCGGC
GCATTACGTGCGCCAGGCGCTCTGGAACTGTTTCTCGGTAATGCCGGAACCGCGATGCGTCCGTTAGCGGCAGCGCTATG
TCTGGGGCAAAATGAGATAGTGTTAACCGGCGAACCGCGTATGAAAGAGCGTCCGATAGGCCATCTGGTCGATTCGCTGC
GTCAGGGCGGGGCGAATATTGATTACCTGGAGCAGGAAAACTATCCGCCCCTGCGTCTGCGCGGCGGTTTTACCGGCGGC
GACATTGAGGTTGATGGTAGCGTTTCCAGCCAGTTCCTGACCGCTCTGCTGATGACGGCGCCGCTGGCCCCTAAAGACAC
AATTATTCGCGTTAAAGGCGAACTGGTATCAAAACCTTACATCGATATCACGCTAAATTTAATGAAAACCTTTGGCGTGG
AGATAGCGAACCACCACTACCAACAATTTGTCGTGAAGGGAGGTCAACAGTATCACTCTCCAGGTCGCTATCTGGTCGAG
GGCGATGCCTCGTCAGCGTCCTATTTTCTCGCCGCTGGGGCGATAAAAGGCGGCACGGTAAAAGTGACCGGAATTGGCCG
CAAAAGTATGCAGGGCGATATTCGTTTTGCCGATGTGCTGGAGAAAATGGGCGCGACCATTACCTGGGGCGATGATTTTA
TTGCCTGCACGCGCGGTGAATTGCACGCCATAGATATGGATATGAACCATATTCCGGATGCGGCGATGACGATTGCCACC
ACGGCGCTGTTTGCGAAAGGAACCACGACGTTGCGCAATATTTATAACTGGCGAGTGAAAGAAACCGATCGCCTGTTCGC
GATGGCGACCGAGCTACGTAAAGTGGGCGCTGAAGTCGAAGAAGGGCACGACTATATTCGTATCACGCCGCCGGCGAAGC
TCCAACACGCGGATATTGGCACGTACAACGACCACCGTATGGCGATGTGCTTCTCACTGGTCGCACTGTCCGATACGCCA
GTTACGATCCTGGACCCTAAATGTACCGCAAAAACGTTCCCTGATTATTTCGAACAACTGGCGCGAATGAGTACGCCTGC
CTAA

Upstream 100 bases:

>100_bases
ATGATCGATTTTGAGCGTCGCCACGGCTAATACGTTTCTTTTTTCATCCCCACGGCCAGTCTGTGGGGTTTTTATTTCTG
TTTTTTGAGAGTTGAGTTTC

Downstream 100 bases:

>100_bases
GTCTTCTGTTGCGCCAGTCGACGGGCTGGCGCGCCGAGTCCGTATTCGCACTATTTTTATAATTATGACTAATGCTAATT
TGTTGATGATTTAACACATT

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MESLTLQPIARVDGAINLPGSKSVSNRALLLAALACGKTALTNLLDSDDVRHMLNALSALGINYTLSADRTRCDITGNGG
ALRAPGALELFLGNAGTAMRPLAAALCLGQNEIVLTGEPRMKERPIGHLVDSLRQGGANIDYLEQENYPPLRLRGGFTGG
DIEVDGSVSSQFLTALLMTAPLAPKDTIIRVKGELVSKPYIDITLNLMKTFGVEIANHHYQQFVVKGGQQYHSPGRYLVE
GDASSASYFLAAGAIKGGTVKVTGIGRKSMQGDIRFADVLEKMGATITWGDDFIACTRGELHAIDMDMNHIPDAAMTIAT
TALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPAKLQHADIGTYNDHRMAMCFSLVALSDTP
VTILDPKCTAKTFPDYFEQLARMSTPA

Sequences:

>Translated_427_residues
MESLTLQPIARVDGAINLPGSKSVSNRALLLAALACGKTALTNLLDSDDVRHMLNALSALGINYTLSADRTRCDITGNGG
ALRAPGALELFLGNAGTAMRPLAAALCLGQNEIVLTGEPRMKERPIGHLVDSLRQGGANIDYLEQENYPPLRLRGGFTGG
DIEVDGSVSSQFLTALLMTAPLAPKDTIIRVKGELVSKPYIDITLNLMKTFGVEIANHHYQQFVVKGGQQYHSPGRYLVE
GDASSASYFLAAGAIKGGTVKVTGIGRKSMQGDIRFADVLEKMGATITWGDDFIACTRGELHAIDMDMNHIPDAAMTIAT
TALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPAKLQHADIGTYNDHRMAMCFSLVALSDTP
VTILDPKCTAKTFPDYFEQLARMSTPA
>Mature_427_residues
MESLTLQPIARVDGAINLPGSKSVSNRALLLAALACGKTALTNLLDSDDVRHMLNALSALGINYTLSADRTRCDITGNGG
ALRAPGALELFLGNAGTAMRPLAAALCLGQNEIVLTGEPRMKERPIGHLVDSLRQGGANIDYLEQENYPPLRLRGGFTGG
DIEVDGSVSSQFLTALLMTAPLAPKDTIIRVKGELVSKPYIDITLNLMKTFGVEIANHHYQQFVVKGGQQYHSPGRYLVE
GDASSASYFLAAGAIKGGTVKVTGIGRKSMQGDIRFADVLEKMGATITWGDDFIACTRGELHAIDMDMNHIPDAAMTIAT
TALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPAKLQHADIGTYNDHRMAMCFSLVALSDTP
VTILDPKCTAKTFPDYFEQLARMSTPA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=427, Percent_Identity=89.4613583138173, Blast_Score=777, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6320332, Length=446, Percent_Identity=39.6860986547085, Blast_Score=263, Evalue=3e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 46133; Mature: 46133

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLTLQPIARVDGAINLPGSKSVSNRALLLAALACGKTALTNLLDSDDVRHMLNALSAL
CCCCCCCHHHHCCCEEECCCCCCCCCHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHHHHC
GINYTLSADRTRCDITGNGGALRAPGALELFLGNAGTAMRPLAAALCLGQNEIVLTGEPR
CCEEEEECCCEEEEEECCCCEEECCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEECCCC
MKERPIGHLVDSLRQGGANIDYLEQENYPPLRLRGGFTGGDIEVDGSVSSQFLTALLMTA
CCCCCHHHHHHHHHHCCCCCCEECCCCCCCEEEECCCCCCCEEECCCHHHHHHHHHHHHC
PLAPKDTIIRVKGELVSKPYIDITLNLMKTFGVEIANHHYQQFVVKGGQQYHSPGRYLVE
CCCCCCEEEEEECCCCCCCEEEEEHEEHHHHCHHHHHHHHHHHHHCCCHHHCCCCCEEEE
GDASSASYFLAAGAIKGGTVKVTGIGRKSMQGDIRFADVLEKMGATITWGDDFIACTRGE
CCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCEEEECCCEEEECCCC
LHAIDMDMNHIPDAAMTIATTALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVE
EEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCEECCHHHHHHHHHHHHHHCCHHH
EGHDYIRITPPAKLQHADIGTYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQL
CCCCEEEECCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHH
ARMSTPA
HHHCCCC
>Mature Secondary Structure
MESLTLQPIARVDGAINLPGSKSVSNRALLLAALACGKTALTNLLDSDDVRHMLNALSAL
CCCCCCCHHHHCCCEEECCCCCCCCCHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHHHHC
GINYTLSADRTRCDITGNGGALRAPGALELFLGNAGTAMRPLAAALCLGQNEIVLTGEPR
CCEEEEECCCEEEEEECCCCEEECCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEECCCC
MKERPIGHLVDSLRQGGANIDYLEQENYPPLRLRGGFTGGDIEVDGSVSSQFLTALLMTA
CCCCCHHHHHHHHHHCCCCCCEECCCCCCCEEEECCCCCCCEEECCCHHHHHHHHHHHHC
PLAPKDTIIRVKGELVSKPYIDITLNLMKTFGVEIANHHYQQFVVKGGQQYHSPGRYLVE
CCCCCCEEEEEECCCCCCCEEEEEHEEHHHHCHHHHHHHHHHHHHCCCHHHCCCCCEEEE
GDASSASYFLAAGAIKGGTVKVTGIGRKSMQGDIRFADVLEKMGATITWGDDFIACTRGE
CCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCEEEECCCEEEECCCC
LHAIDMDMNHIPDAAMTIATTALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVE
EEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCEECCHHHHHHHHHHHHHHCCHHH
EGHDYIRITPPAKLQHADIGTYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQL
CCCCEEEECCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHH
ARMSTPA
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA