| Definition | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome. |
|---|---|
| Accession | NC_003197 |
| Length | 4,857,432 |
Click here to switch to the map view.
The map label for this gene is secA [H]
Identifier: 16763526
GI number: 16763526
Start: 158689
End: 161394
Strand: Direct
Name: secA [H]
Synonym: STM0136
Alternate gene names: 16763526
Gene position: 158689-161394 (Clockwise)
Preceding gene: 161353611
Following gene: 16763527
Centisome position: 3.27
GC content: 53.88
Gene sequence:
>2706_bases ATGCTAATCAAATTATTAACCAAAGTATTCGGTAGCCGTAACGATCGTACGCTGCGTCGTATGCGTAAGGCCGTCAGCCT TATTAATGCGATGGAACCGGAGATGGAAAAACTCTCCGATGACGAACTGAAAGCGAAAACCAACGAATTTCGCGCCCGTA TTGAAAAAGGCGAAAGCGTAGAGAGCCTGATTCCGGAAGCGTTCGCGGTGGTGCGTGAAGCCAGTAAACGCGTCTTTGGG ATGCGTCACTTCGACGTTCAGCTATTGGGTGGTATGGTGCTCAACGATCGTTGTATCGCCGAAATGCGTACTGGTGAAGG TAAGACGCTGACCGCAACGCTGCCAGCCTACCTGAACGCGCTGTCCGGCAAAGGCGTTCATGTGGTAACCGTGAACGACT ATTTGGCGCAGCGTGACGCCGAAAACAACCGTCCGCTATTCGAATTCCTCGGTATGTCCGTTGGTATCAACCTGCCAGGT ATGCCTGCGCCAGCCAAACGTGAAGCTTACGCTGCCGACATCACTTACGGCACTAACAACGAATACGGTTTTGACTACCT GCGCGACAACATGGCGTTCAGCCCGGAAGAGCGCGTGCAGCGTAAACTGCATTATGCGCTGGTGGATGAGGTCGACTCCA TCCTGATCGATGAAGCGCGTACGCCGCTGATCATTTCCGGCCCGGCGGAAGATAGCTCGGAAATGTACAAAAAAGTGAAC AAAATCATTCCGCACCTGATTCGTCAGGAGAAAGAAGATTCTGACACTTTCCAGGGCGAAGGCCACTTCTCCGTTGATGA GAAAGCGCGCCAGGTTAACCTGACCGAACGCGGTCTGGTGCTGATTGAAGAGCTACTGGTGCAAGAAGGCATTATGGATG AGGGCGAGTCGCTCTACTCGCCTGGCAATATTATGCTGATGCATCACGTCACCGCCGCGCTGCGCGCGCACGCGCTGTTT ACCCGTGACGTGGATTACATTGTGAAAGACGGCGAAGTCATCATTGTTGATGAACATACCGGTCGTACCATGCAGGGGCG TCGCTGGTCTGACGGTCTGCACCAGGCGGTAGAAGCGAAAGAAGGCGTTGAAATTCAGAATGAAAACCAGACGCTGGCGT CTATCACCTTCCAGAACTACTTCCGTCTGTATGAAAAGCTGGCCGGTATGACCGGTACGGCGGATACTGAAGCCTTCGAA TTTAGCTCTATCTATAAGCTGGACACCGTCGTTGTTCCGACCAACCGTCCGATGATCCGTAAAGATTTGCCGGATCTGGT CTACATGACCGAAGCGGAAAAAATCCAGGCCATTATCGAAGATATTAAAGAACGTACCGCGAACGGTCAGCCAGTGCTGG TCGGGACGATTTCTATCGAGAAATCTGAAGTGGTCTCCAGAGAGCTGACCAAAGCGGGCATCAAACATAACGTACTGAAC GCAAAATTCCACGCCAACGAAGCAGGCATCGTTGCGCAGGCTGGTTATCCAGCGGCGGTCACTATCGCTACCAACATGGC GGGTCGTGGTACTGATATTATGCTGGGCGGTAGCTGGCAGGCGGAAGTCGCCGCGCTGGAAGCGCCGACGGAAGAACAGA TTGCGCAGATTAAAGCGGACTGGCAGGTACGCCATGACGCGGTTCTGGCTGCCGGCGGTCTGCATATCATTGGCACCGAG CGCCATGAATCCCGCCGTATCGACAACCAGCTGCGTGGCCGTTCCGGTCGCCAGGGCGATCCGGGTTCTTCCCGTTTCTA CCTGTCGATGGAAGATGCGCTGATGCGTATTTTCGCCTCCGATCGTGTCTCCGGTATGATGCGTAAACTGGGAATGAAGC CGGGCGAAGCGATTGAGCACCCGTGGGTGACGAAAGCTATCGCTAACGCGCAGCGTAAAGTAGAAAGCCGTAACTTCGAT ATTCGTAAGCAACTGCTGGAATATGATGATGTGGCGAACGATCAGCGCCGTGCAATTTATACCCAGCGTAACGAACTGCT GGATGTGTCTGACGTGAGCGACACCATTAACAGCATTCGCGAAGATGTCTTTAAGGCGACTATCGACGCCTACATTCCGC CGCAGTCGCTGGAAGAGATGTGGGACATCCCGGGTTTGCAGGAACGCCTGAAAAACGACTTCGACCTGGAGATGCCGATT GCCGAATGGCTGGATAAAGAGCCGGAGCTGCATGAGGAGACGCTGCGTGAGCGCATCCTGGCGCAGTCCATCGAGGTGTA TCAGCGTAAAGAAGAGGTGGTTGGCGCTGAAATGATGCGTCATTTCGAAAAAGGCGTGATGCTGCAAACGCTCGATTCCC TGTGGAAAGAGCATCTGGCGGCGATGGATTACCTGCGTCAGGGTATTCATCTGCGTGGCTATGCGCAAAAAGATCCGAAG CAGGAATACAAGCGCGAATCCTTCGCTATGTTCGCCGCGATGCTGGAATCGCTGAAATATGAAGTAATCAGTACCCTGAG CAAAGTCCAGGTACGTATGCCGGAAGAGGTCGAAGCGATGGAAATGCAGCGTCGCGAAGAGGCGGAGCGCCTGGCGCAGA TGCAGCAGCTAAGCCATCAGGATGACGATGCCGCCGTGGCTGCCGATCTGGCCGCCCAAACCGGCGAACGTAAGATTGGA CGTAACGATCCTTGCCCTTGCGGTTCTGGTAAGAAATACAAACAGTGTCACGGTCGCCTGAGCTAA
Upstream 100 bases:
>100_bases GCGCAGGGTATCCGCGCCGGTCCGCAACGTCTCAGCTAACGAAAAAAGACCCTTTTACTTTATTTGTAGCTCCGCGGCGC GGGGCATTTGAGACTTTATT
Downstream 100 bases:
>100_bases TGCGATAAACTTACCGGCCTGATAAGACATAATGTGTTGCCATCAGGTCAGTACTGGCATTATTGCCGAAGGGCGCTACG CTTATTCGGCCTGGCATTGA
Product: preprotein translocase subunit SecA
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 901; Mature: 901
Protein sequence:
>901_residues MLIKLLTKVFGSRNDRTLRRMRKAVSLINAMEPEMEKLSDDELKAKTNEFRARIEKGESVESLIPEAFAVVREASKRVFG MRHFDVQLLGGMVLNDRCIAEMRTGEGKTLTATLPAYLNALSGKGVHVVTVNDYLAQRDAENNRPLFEFLGMSVGINLPG MPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKKVN KIIPHLIRQEKEDSDTFQGEGHFSVDEKARQVNLTERGLVLIEELLVQEGIMDEGESLYSPGNIMLMHHVTAALRAHALF TRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVEIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFE FSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTANGQPVLVGTISIEKSEVVSRELTKAGIKHNVLN AKFHANEAGIVAQAGYPAAVTIATNMAGRGTDIMLGGSWQAEVAALEAPTEEQIAQIKADWQVRHDAVLAAGGLHIIGTE RHESRRIDNQLRGRSGRQGDPGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFD IRKQLLEYDDVANDQRRAIYTQRNELLDVSDVSDTINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLEMPI AEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPK QEYKRESFAMFAAMLESLKYEVISTLSKVQVRMPEEVEAMEMQRREEAERLAQMQQLSHQDDDAAVAADLAAQTGERKIG RNDPCPCGSGKKYKQCHGRLS
Sequences:
>Translated_901_residues MLIKLLTKVFGSRNDRTLRRMRKAVSLINAMEPEMEKLSDDELKAKTNEFRARIEKGESVESLIPEAFAVVREASKRVFG MRHFDVQLLGGMVLNDRCIAEMRTGEGKTLTATLPAYLNALSGKGVHVVTVNDYLAQRDAENNRPLFEFLGMSVGINLPG MPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKKVN KIIPHLIRQEKEDSDTFQGEGHFSVDEKARQVNLTERGLVLIEELLVQEGIMDEGESLYSPGNIMLMHHVTAALRAHALF TRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVEIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFE FSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTANGQPVLVGTISIEKSEVVSRELTKAGIKHNVLN AKFHANEAGIVAQAGYPAAVTIATNMAGRGTDIMLGGSWQAEVAALEAPTEEQIAQIKADWQVRHDAVLAAGGLHIIGTE RHESRRIDNQLRGRSGRQGDPGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFD IRKQLLEYDDVANDQRRAIYTQRNELLDVSDVSDTINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLEMPI AEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPK QEYKRESFAMFAAMLESLKYEVISTLSKVQVRMPEEVEAMEMQRREEAERLAQMQQLSHQDDDAAVAADLAAQTGERKIG RNDPCPCGSGKKYKQCHGRLS >Mature_901_residues MLIKLLTKVFGSRNDRTLRRMRKAVSLINAMEPEMEKLSDDELKAKTNEFRARIEKGESVESLIPEAFAVVREASKRVFG MRHFDVQLLGGMVLNDRCIAEMRTGEGKTLTATLPAYLNALSGKGVHVVTVNDYLAQRDAENNRPLFEFLGMSVGINLPG MPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKKVN KIIPHLIRQEKEDSDTFQGEGHFSVDEKARQVNLTERGLVLIEELLVQEGIMDEGESLYSPGNIMLMHHVTAALRAHALF TRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVEIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFE FSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTANGQPVLVGTISIEKSEVVSRELTKAGIKHNVLN AKFHANEAGIVAQAGYPAAVTIATNMAGRGTDIMLGGSWQAEVAALEAPTEEQIAQIKADWQVRHDAVLAAGGLHIIGTE RHESRRIDNQLRGRSGRQGDPGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFD IRKQLLEYDDVANDQRRAIYTQRNELLDVSDVSDTINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLEMPI AEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPK QEYKRESFAMFAAMLESLKYEVISTLSKVQVRMPEEVEAMEMQRREEAERLAQMQQLSHQDDDAAVAADLAAQTGERKIG RNDPCPCGSGKKYKQCHGRLS
Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the pr
COG id: COG0653
COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the secA family [H]
Homologues:
Organism=Escherichia coli, GI1786287, Length=900, Percent_Identity=95.1111111111111, Blast_Score=1773, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004027 - InterPro: IPR000185 - InterPro: IPR020937 - InterPro: IPR011115 - InterPro: IPR014018 - InterPro: IPR011130 - InterPro: IPR011116 [H]
Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW [H]
EC number: NA
Molecular weight: Translated: 101827; Mature: 101827
Theoretical pI: Translated: 5.17; Mature: 5.17
Prosite motif: PS01312 SECA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 4.1 %Met (Translated Protein) 4.6 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 4.1 %Met (Mature Protein) 4.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLIKLLTKVFGSRNDRTLRRMRKAVSLINAMEPEMEKLSDDELKAKTNEFRARIEKGESV CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHCCCCH ESLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNDRCIAEMRTGEGKTLTATLPAYLNA HHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEEEHHHHHHH LSGKGVHVVTVNDYLAQRDAENNRPLFEFLGMSVGINLPGMPAPAKREAYAADITYGTNN HCCCCEEEEEECHHHHHCCCCCCCCHHHHHCCHHCCCCCCCCCCCCCCCEEEEEEECCCC EYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKKVN CCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHH KIIPHLIRQEKEDSDTFQGEGHFSVDEKARQVNLTERGLVLIEELLVQEGIMDEGESLYS HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHCC PGNIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAK CCCEEEHHHHHHHHHHHHHHHCCHHHEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHH EGVEIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIR CCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHEEEEEEEEECCCCCHHH KDLPDLVYMTEAEKIQAIIEDIKERTANGQPVLVGTISIEKSEVVSRELTKAGIKHNVLN HCCCHHEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHCCCC AKFHANEAGIVAQAGYPAAVTIATNMAGRGTDIMLGGSWQAEVAALEAPTEEQIAQIKAD CEEECCCCCEEEECCCCEEEEEEECCCCCCCEEEECCCCCHHHHEECCCCHHHHHHHHHH WQVRHDAVLAAGGLHIIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSMEDALMRIFAS HHHHHHHEEEECCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHH DRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIY HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHH TQRNELLDVSDVSDTINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLEMPI HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHCCCCCCCCCH AEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLA HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH AMDYLRQGIHLRGYAQKDPKQEYKRESFAMFAAMLESLKYEVISTLSKVQVRMPEEVEAM HHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH EMQRREEAERLAQMQQLSHQDDDAAVAADLAAQTGERKIGRNDPCPCGSGKKYKQCHGRL HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCC S C >Mature Secondary Structure MLIKLLTKVFGSRNDRTLRRMRKAVSLINAMEPEMEKLSDDELKAKTNEFRARIEKGESV CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHCCCCH ESLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNDRCIAEMRTGEGKTLTATLPAYLNA HHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEEEHHHHHHH LSGKGVHVVTVNDYLAQRDAENNRPLFEFLGMSVGINLPGMPAPAKREAYAADITYGTNN HCCCCEEEEEECHHHHHCCCCCCCCHHHHHCCHHCCCCCCCCCCCCCCCEEEEEEECCCC EYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKKVN CCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHH KIIPHLIRQEKEDSDTFQGEGHFSVDEKARQVNLTERGLVLIEELLVQEGIMDEGESLYS HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHCC PGNIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAK CCCEEEHHHHHHHHHHHHHHHCCHHHEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHH EGVEIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIR CCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHEEEEEEEEECCCCCHHH KDLPDLVYMTEAEKIQAIIEDIKERTANGQPVLVGTISIEKSEVVSRELTKAGIKHNVLN HCCCHHEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHCCCC AKFHANEAGIVAQAGYPAAVTIATNMAGRGTDIMLGGSWQAEVAALEAPTEEQIAQIKAD CEEECCCCCEEEECCCCEEEEEEECCCCCCCEEEECCCCCHHHHEECCCCHHHHHHHHHH WQVRHDAVLAAGGLHIIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSMEDALMRIFAS HHHHHHHEEEECCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHH DRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIY HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHH TQRNELLDVSDVSDTINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLEMPI HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHCCCCCCCCCH AEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLA HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH AMDYLRQGIHLRGYAQKDPKQEYKRESFAMFAAMLESLKYEVISTLSKVQVRMPEEVEAM HHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH EMQRREEAERLAQMQQLSHQDDDAAVAADLAAQTGERKIGRNDPCPCGSGKKYKQCHGRL HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCC S C
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA