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The map label for this gene is citC2 [H]

Identifier: 16763448

GI number: 16763448

Start: 68637

End: 69680

Strand: Direct

Name: citC2 [H]

Synonym: STM0058

Alternate gene names: 16763448

Gene position: 68637-69680 (Clockwise)

Preceding gene: 16763441

Following gene: 16763449

Centisome position: 1.41

GC content: 53.74

Gene sequence:

>1044_bases
ATGCAGAATAGAGTGAATCTAATATTTAAACGCATTTATTTGCAAAAGGATGTATTGCGTCGCGAGTCGGTCGCCATGTT
TCTGGAGGGCGTGGGACTCGCCCTGGAAGACGATTGTGAAATCGCGGTATGCGCATATTGGCAGGGTGAGATAGTCGGGT
GCGGTTCTCTGGCCGGGAGCGTACTGAAATGCATCGCCGTTTCCCCGGTTTTACAAGGGGAAGGGCTCAGCCTCAAACTG
CTGACCGAGCTGCTTACATTGGCCTACGAGTTAAACCGCAGCGAGCTTTTCCTGTTCACTAAGCCGCAAAATCGGTTGCT
GTTTTCTGGCGCGGGGTTTTGGCCCATTGCGCAGGCAGGTGAGCTGGCGGTGTTAATGGAGAACAGCAGTGAACGGTTAG
CGCGCTTTTGTCGCCAACTGGCGCTTTATCGTCAACCGGGAAAAACGATCGGCGCCATCGTCATGAACGCCAATCCGTTT
ACATTGGGCCACCGTTATCTGGTGGAGCAAGCGGCTGCGGCCTGTGACTGGTTGCATCTGTTTGTAGTCAAAGAAGATGC
TTCATTTTTTTCCTATACCGACCGTTGGGCGCTGATCGAACAAGGAATCGCGGGCATTGACAACGTCACGTTGCATTCCG
GCTCCGCTTATATGATCTCGCGTGCGACGTTTCCCGGCTATTTCCTCAAAGAAAAAGGGGTTGTGGACGACTGCCATTGC
CAGATCGATCTGCAACTCTTCCGTGAACATCTGGCTCCAGCGCTGGGGATTACCCATCGTTTTGTCGGCAGTGAACCGTT
TTGTCCTCTGACCTGTGCCTATAACCAGCGAATGCACGACATTTTGCACGATCCGAAGCGTAGCGGCCCGGTTATTGAGG
TCGTCGAGCTGGCGCGGGTGGAGAAAAACGGCGCGGCTATTTCCGCCTCTCGCGTCAGAAAACTGTATAGCGAACGTAAT
TGGTCGGCAATAAGCGCGCTGGTGCCTGCTGGCACCCTGGCATATCTGCAGCGGCATGCCGCCAGACACACTGAAACCAT
ATGA

Upstream 100 bases:

>100_bases
AAAAACCATAAAGCTTATAAAAGCAAGGGGGAAAGTGTGATGTCTATTCCAGACGAGTAATACAAACGCTGGCGAAATAT
GCGACGTTATTTGCTGACGG

Downstream 100 bases:

>100_bases
CGTAACACCGTTAACAAGGAACATAACTAATGAAAATCATTAAAGATGCCCTGGCAGGCACGCTGGAATCCAGCGATGTG
ATGATCAGGATTGGTCCATC

Product: citrate lyase synthetase

Products: NA

Alternate protein names: Acetate:SH-citrate lyase ligase; Citrate lyase synthetase [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MQNRVNLIFKRIYLQKDVLRRESVAMFLEGVGLALEDDCEIAVCAYWQGEIVGCGSLAGSVLKCIAVSPVLQGEGLSLKL
LTELLTLAYELNRSELFLFTKPQNRLLFSGAGFWPIAQAGELAVLMENSSERLARFCRQLALYRQPGKTIGAIVMNANPF
TLGHRYLVEQAAAACDWLHLFVVKEDASFFSYTDRWALIEQGIAGIDNVTLHSGSAYMISRATFPGYFLKEKGVVDDCHC
QIDLQLFREHLAPALGITHRFVGSEPFCPLTCAYNQRMHDILHDPKRSGPVIEVVELARVEKNGAAISASRVRKLYSERN
WSAISALVPAGTLAYLQRHAARHTETI

Sequences:

>Translated_347_residues
MQNRVNLIFKRIYLQKDVLRRESVAMFLEGVGLALEDDCEIAVCAYWQGEIVGCGSLAGSVLKCIAVSPVLQGEGLSLKL
LTELLTLAYELNRSELFLFTKPQNRLLFSGAGFWPIAQAGELAVLMENSSERLARFCRQLALYRQPGKTIGAIVMNANPF
TLGHRYLVEQAAAACDWLHLFVVKEDASFFSYTDRWALIEQGIAGIDNVTLHSGSAYMISRATFPGYFLKEKGVVDDCHC
QIDLQLFREHLAPALGITHRFVGSEPFCPLTCAYNQRMHDILHDPKRSGPVIEVVELARVEKNGAAISASRVRKLYSERN
WSAISALVPAGTLAYLQRHAARHTETI
>Mature_347_residues
MQNRVNLIFKRIYLQKDVLRRESVAMFLEGVGLALEDDCEIAVCAYWQGEIVGCGSLAGSVLKCIAVSPVLQGEGLSLKL
LTELLTLAYELNRSELFLFTKPQNRLLFSGAGFWPIAQAGELAVLMENSSERLARFCRQLALYRQPGKTIGAIVMNANPF
TLGHRYLVEQAAAACDWLHLFVVKEDASFFSYTDRWALIEQGIAGIDNVTLHSGSAYMISRATFPGYFLKEKGVVDDCHC
QIDLQLFREHLAPALGITHRFVGSEPFCPLTCAYNQRMHDILHDPKRSGPVIEVVELARVEKNGAAISASRVRKLYSERN
WSAISALVPAGTLAYLQRHAARHTETI

Specific function: Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase [H]

COG id: COG3053

COG function: function code C; Citrate lyase synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI87081765, Length=332, Percent_Identity=49.3975903614458, Blast_Score=339, Evalue=1e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005216
- InterPro:   IPR013166
- InterPro:   IPR004821
- InterPro:   IPR014729 [H]

Pfam domain/function: PF08218 Citrate_ly_lig [H]

EC number: =6.2.1.22 [H]

Molecular weight: Translated: 38635; Mature: 38635

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNRVNLIFKRIYLQKDVLRRESVAMFLEGVGLALEDDCEIAVCAYWQGEIVGCGSLAGS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEEECCCEEECHHHHHH
VLKCIAVSPVLQGEGLSLKLLTELLTLAYELNRSELFLFTKPQNRLLFSGAGFWPIAQAG
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCCCCCC
ELAVLMENSSERLARFCRQLALYRQPGKTIGAIVMNANPFTLGHRYLVEQAAAACDWLHL
CEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCEEEE
FVVKEDASFFSYTDRWALIEQGIAGIDNVTLHSGSAYMISRATFPGYFLKEKGVVDDCHC
EEEECCCCHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCEEEECCCCCCCCEE
QIDLQLFREHLAPALGITHRFVGSEPFCPLTCAYNQRMHDILHDPKRSGPVIEVVELARV
EEEHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHH
EKNGAAISASRVRKLYSERNWSAISALVPAGTLAYLQRHAARHTETI
HCCCCEECHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQNRVNLIFKRIYLQKDVLRRESVAMFLEGVGLALEDDCEIAVCAYWQGEIVGCGSLAGS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEEECCCEEECHHHHHH
VLKCIAVSPVLQGEGLSLKLLTELLTLAYELNRSELFLFTKPQNRLLFSGAGFWPIAQAG
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCCCCCC
ELAVLMENSSERLARFCRQLALYRQPGKTIGAIVMNANPFTLGHRYLVEQAAAACDWLHL
CEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCEEEE
FVVKEDASFFSYTDRWALIEQGIAGIDNVTLHSGSAYMISRATFPGYFLKEKGVVDDCHC
EEEECCCCHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCEEEECCCCCCCCEE
QIDLQLFREHLAPALGITHRFVGSEPFCPLTCAYNQRMHDILHDPKRSGPVIEVVELARV
EEEHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHH
EKNGAAISASRVRKLYSERNWSAISALVPAGTLAYLQRHAARHTETI
HCCCCEECHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7830578 [H]