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The map label for this gene is citS [H]

Identifier: 16763447

GI number: 16763447

Start: 67052

End: 68392

Strand: Reverse

Name: citS [H]

Synonym: STM0057

Alternate gene names: 16763447

Gene position: 68392-67052 (Counterclockwise)

Preceding gene: 16763459

Following gene: 16763446

Centisome position: 1.41

GC content: 49.37

Gene sequence:

>1341_bases
ATGACCAACATGACCCAGGCTTCGGCGACGGAGAAAAAGGGGGCTAGCGATTTACTCAGATTCAAAATCTTTGGTATGCC
GCTACCGCTTTATGCCTTTGCATTAATTACTTTATTACTTTCTCATTTTTATAATGCTATACCGACTGACTTAGTAGGTG
GTTTTGCCCTTATGTTTGTGATGGGGGCCATTTTTGGTGAAATCGGCAAACGTTTACCGATCTTCAATAAATATATTGGC
GGCGCACCGGTTATGATATTTCTGGTTGCAGCTTATTTTGTCTATGCTGGCATATTTACGCAGAAAGAAATTGATGCGAT
CAGCAACGTAATGGATAAAAGCAACTTCCTTAACCTGTTTATCGCAGTGTTGATCACAGGCGCGATCCTGTCGGTAAACC
GTAAGCTGCTATTAAAATCACTGCTGGGCTATATCCCAACCATCCTCGCCGGGATTGTCGGCGCGTCCCTTTTCGGTATC
GTCATTGGTCTGTGCTTCGGTATCCCGGTCGACCGTATCATGATGCTGTACGTTCTGCCGATTATGGGCGGTGGTAACGG
CGCGGGCGCCGTGCCTCTGTCTGAAATTTATCACTCGGTTACCGGACGTTCTCGCGAAGAGTATTACTCAACGGCTATTG
CTATTCTGACCATTGCGAATATCTTCGCCATTATTTTCGCCGCCCTCCTCGATATGATAGGCAAAAAATACACCTGGCTT
AGCGGTGAAGGCGAGTTGGTTCGTAAGGCTTCCTTCAAAACCGAAGATGATGAAAAGGCCGGTCAGATTACCCATCGTGA
AACGGCGGTTGGCATGGTGCTATCCACCACCTGCTTCCTGCTGGCCTATGTTGTTGCCAAGAAAATTCTGCCAAGCATCG
GCGGCGTCTCTATTCACTACTTCGCCTGGATGGTCCTGATTGTTGCTGCGCTGAACGCATCAGGTCTTTGCTCACCGGAG
ATTAAAGCCGGGGCGAAACGTCTTTCTGACTTCTTCTCCAAACAGCTACTGTGGGTGCTGATGGTAGGTGTGGGTGTTTG
CTACACCGATCTGCAAGAGATCATCGATGCCCTGACGTTCGCGAACGTAGTTATCGCCGCAATCATTGTGGTCGGCGCAG
TCGTTGGCGCAGCTATCGGGGGCTGGTTGATTGGCTTCTACCCGATTGAATCATCCATTACTGCGGGTCTTTGTATGGCC
AACCGCGGCGGCTCCGGCGATCTGGAAGTGCTCTCCGCCTGTAACCGTATGAACCTCATTTCATATGCACAAATTTCCTC
TCGTCTGGGCGGCGGTATTGTGCTGGTTATCGCTAGCATCGTGTTCAGCATGATGGTGTAA

Upstream 100 bases:

>100_bases
AAAAACACAACCATTCAGTGAAGATAGTCACATCTCATGGTTCATTGAATTTATTAGTATGCGCGGGTCTTGTTACCCAT
CAATACACAGGAAAATGTTT

Downstream 100 bases:

>100_bases
AAAAACGCACGGCGGTGTCTTGGCAGCAAACGACCTGGAGAAAAGTAGAGGCCAAAGCCAGAGGTGGCCAAGGGAAATCC
ACTCTACTCCTTAGCCGGAT

Product: citrate-sodium symporter

Products: NA

Alternate protein names: Citrate carrier protein; Citrate transporter [H]

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MTNMTQASATEKKGASDLLRFKIFGMPLPLYAFALITLLLSHFYNAIPTDLVGGFALMFVMGAIFGEIGKRLPIFNKYIG
GAPVMIFLVAAYFVYAGIFTQKEIDAISNVMDKSNFLNLFIAVLITGAILSVNRKLLLKSLLGYIPTILAGIVGASLFGI
VIGLCFGIPVDRIMMLYVLPIMGGGNGAGAVPLSEIYHSVTGRSREEYYSTAIAILTIANIFAIIFAALLDMIGKKYTWL
SGEGELVRKASFKTEDDEKAGQITHRETAVGMVLSTTCFLLAYVVAKKILPSIGGVSIHYFAWMVLIVAALNASGLCSPE
IKAGAKRLSDFFSKQLLWVLMVGVGVCYTDLQEIIDALTFANVVIAAIIVVGAVVGAAIGGWLIGFYPIESSITAGLCMA
NRGGSGDLEVLSACNRMNLISYAQISSRLGGGIVLVIASIVFSMMV

Sequences:

>Translated_446_residues
MTNMTQASATEKKGASDLLRFKIFGMPLPLYAFALITLLLSHFYNAIPTDLVGGFALMFVMGAIFGEIGKRLPIFNKYIG
GAPVMIFLVAAYFVYAGIFTQKEIDAISNVMDKSNFLNLFIAVLITGAILSVNRKLLLKSLLGYIPTILAGIVGASLFGI
VIGLCFGIPVDRIMMLYVLPIMGGGNGAGAVPLSEIYHSVTGRSREEYYSTAIAILTIANIFAIIFAALLDMIGKKYTWL
SGEGELVRKASFKTEDDEKAGQITHRETAVGMVLSTTCFLLAYVVAKKILPSIGGVSIHYFAWMVLIVAALNASGLCSPE
IKAGAKRLSDFFSKQLLWVLMVGVGVCYTDLQEIIDALTFANVVIAAIIVVGAVVGAAIGGWLIGFYPIESSITAGLCMA
NRGGSGDLEVLSACNRMNLISYAQISSRLGGGIVLVIASIVFSMMV
>Mature_445_residues
TNMTQASATEKKGASDLLRFKIFGMPLPLYAFALITLLLSHFYNAIPTDLVGGFALMFVMGAIFGEIGKRLPIFNKYIGG
APVMIFLVAAYFVYAGIFTQKEIDAISNVMDKSNFLNLFIAVLITGAILSVNRKLLLKSLLGYIPTILAGIVGASLFGIV
IGLCFGIPVDRIMMLYVLPIMGGGNGAGAVPLSEIYHSVTGRSREEYYSTAIAILTIANIFAIIFAALLDMIGKKYTWLS
GEGELVRKASFKTEDDEKAGQITHRETAVGMVLSTTCFLLAYVVAKKILPSIGGVSIHYFAWMVLIVAALNASGLCSPEI
KAGAKRLSDFFSKQLLWVLMVGVGVCYTDLQEIIDALTFANVVIAAIIVVGAVVGAAIGGWLIGFYPIESSITAGLCMAN
RGGSGDLEVLSACNRMNLISYAQISSRLGGGIVLVIASIVFSMMV

Specific function: Uptake of citrate across the boundary membrane with the concomitant uptake of a sodium ion (symport system) [H]

COG id: COG3493

COG function: function code C; Na+/citrate symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:citrate (SCF) symporter family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004679
- InterPro:   IPR018025 [H]

Pfam domain/function: PF03390 2HCT [H]

EC number: NA

Molecular weight: Translated: 47622; Mature: 47491

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNMTQASATEKKGASDLLRFKIFGMPLPLYAFALITLLLSHFYNAIPTDLVGGFALMFV
CCCCCCCCHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH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HHHHHHHHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577734; 8810332 [H]