Click here to switch to the map view.

The map label for this gene is dam [H]

Identifier: 167625984

GI number: 167625984

Start: 4963978

End: 4964817

Strand: Reverse

Name: dam [H]

Synonym: Shal_4079

Alternate gene names: 167625984

Gene position: 4964817-4963978 (Counterclockwise)

Preceding gene: 167625985

Following gene: 167625981

Centisome position: 94.99

GC content: 43.69

Gene sequence:

>840_bases
ATGATTAAAAAACAAAGAGCCTTTTTAAAGTGGGCTGGCGGAAAATTTAAACTGATTGAAGTCTTATCAGAGCATTTGCC
TGAAGGCGATCGCCTCGTCGAACCCTTTGTTGGGGCTGGCTCGGTCTTTCTCAATACCCACTACAGCAATTATCTATTGT
GCGATATTAATCATGATTTGATTAACTTGTACAAGATCGTGCAAAAAGAGCCCGATAGATATATCGAAGCTGCCAAGGCA
CTCTTCGTTCCTGAGATGAACGACAAGGAAGCCTACTATAAAGTTCGTACGGCTTTTAATGCCACCAAAGATCCTTTTAC
GCGCTCAGTATATTTCCTATATATGAACCGTCATGGTTTTAATGGCTTATGCCGTTATAACCGTAAGGGAGGCTTCAATG
TGCCGTTTGGTTCGTATAAAAAGCCTTACTTTCCAGAAAAAGAGATCCGTGGCTTTTCAGAAAAGGCGCAAAATGCAGAG
TTTCACTGCATAGGTTATGAACAAGCGATAGATATGACTCAAACGGGTGATGTGGTGTATTGCGATCCGCCTTATGCTCC
TTTGTCATCGACAGCCAGTTTTACGACTTATGTGGGCAGCGGGTTCTCGTTAGATGATCAGGCCCTGCTCGCAAGAAAGG
CACGCCACACGGCGATAGAAAGAGGTATTCCGGTACTCATTAGTAACCATGATATTCCGTTGACGCGTGAGTTATACCAT
GGTGCTCGTTTCGATACGATTCAAGTTCAGCGCAATATTAGTCAGAAGGGCAGTGGCCGTAAAAAGGTCGATGAGCTTAT
AGCGCTGTATGATGATTCATACCATAGTGAGAACGACTAA

Upstream 100 bases:

>100_bases
TGAATATGAGCTACAAGATGTACTTCCAACTCGTGAAATTCAATAATAAACAGAGTACAATCATCAGCTCTCTTTTTTTC
ACAGTGTTCAATCAATTTAA

Downstream 100 bases:

>100_bases
CCCTAACCCCTTTCATTACTCTCAGGCAGTGATTGCTTATCGTAATACCTGCTCAACGATAAGTAACAGCGCTGCCACAA
ACATAATCGCTAATATTATG

Product: DNA adenine methylase

Products: NA

Alternate protein names: DNA adenine methyltransferase; Deoxyadenosyl-methyltransferase; M.VchADam [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MIKKQRAFLKWAGGKFKLIEVLSEHLPEGDRLVEPFVGAGSVFLNTHYSNYLLCDINHDLINLYKIVQKEPDRYIEAAKA
LFVPEMNDKEAYYKVRTAFNATKDPFTRSVYFLYMNRHGFNGLCRYNRKGGFNVPFGSYKKPYFPEKEIRGFSEKAQNAE
FHCIGYEQAIDMTQTGDVVYCDPPYAPLSSTASFTTYVGSGFSLDDQALLARKARHTAIERGIPVLISNHDIPLTRELYH
GARFDTIQVQRNISQKGSGRKKVDELIALYDDSYHSEND

Sequences:

>Translated_279_residues
MIKKQRAFLKWAGGKFKLIEVLSEHLPEGDRLVEPFVGAGSVFLNTHYSNYLLCDINHDLINLYKIVQKEPDRYIEAAKA
LFVPEMNDKEAYYKVRTAFNATKDPFTRSVYFLYMNRHGFNGLCRYNRKGGFNVPFGSYKKPYFPEKEIRGFSEKAQNAE
FHCIGYEQAIDMTQTGDVVYCDPPYAPLSSTASFTTYVGSGFSLDDQALLARKARHTAIERGIPVLISNHDIPLTRELYH
GARFDTIQVQRNISQKGSGRKKVDELIALYDDSYHSEND
>Mature_279_residues
MIKKQRAFLKWAGGKFKLIEVLSEHLPEGDRLVEPFVGAGSVFLNTHYSNYLLCDINHDLINLYKIVQKEPDRYIEAAKA
LFVPEMNDKEAYYKVRTAFNATKDPFTRSVYFLYMNRHGFNGLCRYNRKGGFNVPFGSYKKPYFPEKEIRGFSEKAQNAE
FHCIGYEQAIDMTQTGDVVYCDPPYAPLSSTASFTTYVGSGFSLDDQALLARKARHTAIERGIPVLISNHDIPLTRELYH
GARFDTIQVQRNISQKGSGRKKVDELIALYDDSYHSEND

Specific function: Methylates DNA within the sequence GATC. Directly involved in methyl-directed DNA mismatch repair [H]

COG id: COG0338

COG function: function code L; Site-specific DNA methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789789, Length=269, Percent_Identity=59.8513011152416, Blast_Score=337, Evalue=7e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023095
- InterPro:   IPR002052
- InterPro:   IPR012327 [H]

Pfam domain/function: PF02086 MethyltransfD12 [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 31942; Mature: 31942

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKQRAFLKWAGGKFKLIEVLSEHLPEGDRLVEPFVGAGSVFLNTHYSNYLLCDINHDL
CCCCCCCCEEECCCCCHHHHHHHHHCCCCCHHHHHHCCCCEEEEEECCCCEEEEECCHHH
INLYKIVQKEPDRYIEAAKALFVPEMNDKEAYYKVRTAFNATKDPFTRSVYFLYMNRHGF
HHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHEEEHHHHCCCCCCCCCEEEEEEEECCCC
NGLCRYNRKGGFNVPFGSYKKPYFPEKEIRGFSEKAQNAEFHCIGYEQAIDMTQTGDVVY
CCEEEECCCCCCCCCCCCCCCCCCCHHHHCCCHHHHCCCCEEEECHHHHCCCCCCCCEEE
CDPPYAPLSSTASFTTYVGSGFSLDDQALLARKARHTAIERGIPVLISNHDIPLTRELYH
ECCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHC
GARFDTIQVQRNISQKGSGRKKVDELIALYDDSYHSEND
CCCCCEEEEECCHHCCCCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MIKKQRAFLKWAGGKFKLIEVLSEHLPEGDRLVEPFVGAGSVFLNTHYSNYLLCDINHDL
CCCCCCCCEEECCCCCHHHHHHHHHCCCCCHHHHHHCCCCEEEEEECCCCEEEEECCHHH
INLYKIVQKEPDRYIEAAKALFVPEMNDKEAYYKVRTAFNATKDPFTRSVYFLYMNRHGF
HHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHEEEHHHHCCCCCCCCCEEEEEEEECCCC
NGLCRYNRKGGFNVPFGSYKKPYFPEKEIRGFSEKAQNAEFHCIGYEQAIDMTQTGDVVY
CCEEEECCCCCCCCCCCCCCCCCCCHHHHCCCHHHHCCCCEEEECHHHHCCCCCCCCEEE
CDPPYAPLSSTASFTTYVGSGFSLDDQALLARKARHTAIERGIPVLISNHDIPLTRELYH
ECCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHC
GARFDTIQVQRNISQKGSGRKKVDELIALYDDSYHSEND
CCCCCEEEEECCHHCCCCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11705940 [H]