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The map label for this gene is trpS [H]

Identifier: 167625979

GI number: 167625979

Start: 4960801

End: 4961811

Strand: Reverse

Name: trpS [H]

Synonym: Shal_4074

Alternate gene names: 167625979

Gene position: 4961811-4960801 (Counterclockwise)

Preceding gene: 167625980

Following gene: 167625977

Centisome position: 94.93

GC content: 46.88

Gene sequence:

>1011_bases
ATGACGAACCCTTTAACGAAACCAGTAGTTCTAAGCGGAGCGCAGCCATCAGGCGAGCTGACCATCGGCAACTATATGGG
CGCGTTACGTCAGTGGGTTGCAATGCAAGATAGTCATGATTGCCTTTATTGCGTCGTTGACCTGCATGCGATTACTGTCA
GACAAGATCCTGCCAAACTACGTGAAGCGTGTCTTGATACGTTAGCACTGTATCTGGCTTGTGGTGTTGATCCTAAGAAG
AGCACGGTATTTATTCAGTCTCAAGTTCCACAGCACACACAACTTGGTTGGGCACTAAACTGTTACACCCAGATGGGTGA
GCTAAACCGCATGACGCAGTTTAAAGATAAGTCGCAAAAGCATGCTAACAACATTAACGTGGGTCTATTTAGTTACCCTG
TGTTGATGGCAGCAGATATTTTGCTTTATCAAGCGAATGAGATCCCAGTGGGTCAAGATCAGAAGCAGCATCTAGAGTTG
ACCCGTGATATCGCGACTCGCTTTAACAATGCTTACGGTGAAACTTTCGTGATCCCAGAGCCATTCATCCCTGAGCATGG
TGCTAAGGTGATGTCGCTGCAAGATCCACTAAAGAAGATGTCTAAGTCTGATGATAACCGTAATAACGTTATCGGCTTAC
TTGAAGATCCAAAAGCGATCATGAAGAAGATCAAAAAGGCGATGACAGATGGCCAAGAGCCACCAGTCGTGCGCTTCGAT
GTTGCCGAAAAGCCGGGTGTTTCTAACTTGCTAAGCCTAATGTCAGGCTGTACTGGTCAGTCGATTGCTAGCCTAGAAGC
CGAGTTTGAAGGCAAGATGTATGGTCATTTAAAAGTGGCTACGGGTGACGCCGTTGTCGGTATGCTTGAGCCGCTGCAGC
AGCGCTTTAAAGAGTACCGTGCAGACCATGACTTCTTGAATCAAGTGATGAGAGACGGAGCTGAAAAGGCGCAGGCTCGC
GCTGAGGTGACGATTAAGAACGTTTACGAAAAAATTGGTCTTATCGTTTAA

Upstream 100 bases:

>100_bases
AAGATATTGGGCTAAGCGGCCCTGACGCCGTATGTGAACAATTTAGTGAAATAACCGCGCTACTTAAATTGCGCGATAAA
GCAACGGAGCAATAAACAAG

Downstream 100 bases:

>100_bases
CTCGACGACTAATTTATACTGCTAACTTGAAAGCCAGCAATAGTCGCTGGCTTTTTTATTAGCTTAGTTTTATAAAGTTA
CTGCAGGCTTAACCAGCTCA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTNPLTKPVVLSGAQPSGELTIGNYMGALRQWVAMQDSHDCLYCVVDLHAITVRQDPAKLREACLDTLALYLACGVDPKK
STVFIQSQVPQHTQLGWALNCYTQMGELNRMTQFKDKSQKHANNINVGLFSYPVLMAADILLYQANEIPVGQDQKQHLEL
TRDIATRFNNAYGETFVIPEPFIPEHGAKVMSLQDPLKKMSKSDDNRNNVIGLLEDPKAIMKKIKKAMTDGQEPPVVRFD
VAEKPGVSNLLSLMSGCTGQSIASLEAEFEGKMYGHLKVATGDAVVGMLEPLQQRFKEYRADHDFLNQVMRDGAEKAQAR
AEVTIKNVYEKIGLIV

Sequences:

>Translated_336_residues
MTNPLTKPVVLSGAQPSGELTIGNYMGALRQWVAMQDSHDCLYCVVDLHAITVRQDPAKLREACLDTLALYLACGVDPKK
STVFIQSQVPQHTQLGWALNCYTQMGELNRMTQFKDKSQKHANNINVGLFSYPVLMAADILLYQANEIPVGQDQKQHLEL
TRDIATRFNNAYGETFVIPEPFIPEHGAKVMSLQDPLKKMSKSDDNRNNVIGLLEDPKAIMKKIKKAMTDGQEPPVVRFD
VAEKPGVSNLLSLMSGCTGQSIASLEAEFEGKMYGHLKVATGDAVVGMLEPLQQRFKEYRADHDFLNQVMRDGAEKAQAR
AEVTIKNVYEKIGLIV
>Mature_335_residues
TNPLTKPVVLSGAQPSGELTIGNYMGALRQWVAMQDSHDCLYCVVDLHAITVRQDPAKLREACLDTLALYLACGVDPKKS
TVFIQSQVPQHTQLGWALNCYTQMGELNRMTQFKDKSQKHANNINVGLFSYPVLMAADILLYQANEIPVGQDQKQHLELT
RDIATRFNNAYGETFVIPEPFIPEHGAKVMSLQDPLKKMSKSDDNRNNVIGLLEDPKAIMKKIKKAMTDGQEPPVVRFDV
AEKPGVSNLLSLMSGCTGQSIASLEAEFEGKMYGHLKVATGDAVVGMLEPLQQRFKEYRADHDFLNQVMRDGAEKAQARA
EVTIKNVYEKIGLIV

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=331, Percent_Identity=41.9939577039275, Blast_Score=277, Evalue=8e-75,
Organism=Homo sapiens, GI41352700, Length=179, Percent_Identity=51.9553072625698, Blast_Score=203, Evalue=2e-52,
Organism=Escherichia coli, GI1789786, Length=331, Percent_Identity=71.9033232628399, Blast_Score=517, Evalue=1e-148,
Organism=Caenorhabditis elegans, GI71982800, Length=338, Percent_Identity=35.207100591716, Blast_Score=195, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI71982793, Length=338, Percent_Identity=35.207100591716, Blast_Score=194, Evalue=6e-50,
Organism=Saccharomyces cerevisiae, GI6320474, Length=345, Percent_Identity=40.2898550724638, Blast_Score=238, Evalue=1e-63,
Organism=Drosophila melanogaster, GI24666151, Length=327, Percent_Identity=40.0611620795107, Blast_Score=250, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37340; Mature: 37208

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNPLTKPVVLSGAQPSGELTIGNYMGALRQWVAMQDSHDCLYCVVDLHAITVRQDPAKL
CCCCCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEEEHHHEEECCCHHHH
REACLDTLALYLACGVDPKKSTVFIQSQVPQHTQLGWALNCYTQMGELNRMTQFKDKSQK
HHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHH
HANNINVGLFSYPVLMAADILLYQANEIPVGQDQKQHLELTRDIATRFNNAYGETFVIPE
HCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCC
PFIPEHGAKVMSLQDPLKKMSKSDDNRNNVIGLLEDPKAIMKKIKKAMTDGQEPPVVRFD
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEEEE
VAEKPGVSNLLSLMSGCTGQSIASLEAEFEGKMYGHLKVATGDAVVGMLEPLQQRFKEYR
CCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHC
ADHDFLNQVMRDGAEKAQARAEVTIKNVYEKIGLIV
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TNPLTKPVVLSGAQPSGELTIGNYMGALRQWVAMQDSHDCLYCVVDLHAITVRQDPAKL
CCCCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEEEHHHEEECCCHHHH
REACLDTLALYLACGVDPKKSTVFIQSQVPQHTQLGWALNCYTQMGELNRMTQFKDKSQK
HHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHH
HANNINVGLFSYPVLMAADILLYQANEIPVGQDQKQHLELTRDIATRFNNAYGETFVIPE
HCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCC
PFIPEHGAKVMSLQDPLKKMSKSDDNRNNVIGLLEDPKAIMKKIKKAMTDGQEPPVVRFD
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEEEE
VAEKPGVSNLLSLMSGCTGQSIASLEAEFEGKMYGHLKVATGDAVVGMLEPLQQRFKEYR
CCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHC
ADHDFLNQVMRDGAEKAQARAEVTIKNVYEKIGLIV
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]