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The map label for this gene is yiaY [H]

Identifier: 167625941

GI number: 167625941

Start: 4916701

End: 4917852

Strand: Reverse

Name: yiaY [H]

Synonym: Shal_4036

Alternate gene names: 167625941

Gene position: 4917852-4916701 (Counterclockwise)

Preceding gene: 167625952

Following gene: 167625940

Centisome position: 94.09

GC content: 45.57

Gene sequence:

>1152_bases
ATGAGCACAACATTTTATATGCCTCCTATGTCAATGATGGGTCCAGATGCAATCAAGCAACTTGGTTCGGAATTGAATGC
TAGAAATTTTCACAAGGCATTGATCGTTACCGATAAGGCGCTAGTCGATATTAAGTTGGTTGACCGTCTTACTGAAGAGT
TATCGGCACATAACATCGCCTTTGCCATTTTCGATGGCGTTAAACCTAACCCAACTGAAAATAATATCGAGCAAGGCCTT
AAGCTACTTAGCGCCGAAGATTGTGACTTGGTCATTTCGTTTGGCGGTGGATCTTCCCACGATTGCGCTAAAGGTATCGC
CTTAGTCGCAACAAATGGTGGTCATATTCGTGACTACTCAAAGGGTGTGCATCTATCGACTAAACCGCAGTTACCTCTCG
TGACGGTTAACACTACGGCGGGTACCGCTTCTGAGATGACCATCTTTGCCATTGTGACCAATGAGAAAGATGAGACTAAG
TATCCAGTGGTTGATAAGAACCTAACCCCAATTATTGCAGTGAACGATTCAGAGCTAATGGTTGCTATGCCTAAGTTCTT
AACCGCTGCTACGGGTATGGATGCACTGACTCATGCTGTCGAAGCTTATGTTTCTACTGCCGCGACACCGATCACCGATG
CTTCTGCAATTAAGGCGATTGAGTTGATTTCAAGTAACTTAGAAGCCGTAGTCGATAACGGTGAAAACCGAGAAGCCCGT
GATGCGATGCAATACGGTGAATTCCTAGCGGGTATGGCGTTCTCTAATGCGTCATTAGGTTACGTGCACTCAATGGCTCA
CCAGCTAGGTGGCGTATATGACTTAGTCCATGGTCTATGTAACGCCATTTTGCTACCTCATGTGTCTCGTTTCAATGCTG
CTTTAAGCACTGAACGATTCGCCGATATCGCTAAGGCGATGGGCGTTGATAGCACAGGTATGAATGTTGCTGAAGCCGCA
GAAGCGGGCATCCTTGCTATCGAAGCCTTATCTGAGTCAGTGGGCACAGCGCAGAAGCTTAGCGATCTTGGGGTTAAGCA
AGACAAGTTAGAGTTTATGGCCATTAATGCCCTAAACGATGCCTGCTCTTTAACTAATCCAAGAAAAGCTAGCACCGAAG
AGATCATCAATATTTTCAATCAAGCGATGTAA

Upstream 100 bases:

>100_bases
ACATCAGGGTCACCCAGCCTCTCTTCTGCAAGTATTAATTTTAGTCCGAGGCTGATCAGTTTCTGTTTTTATCAATTTAT
ATTTAGTAAAGGAAACACAA

Downstream 100 bases:

>100_bases
TACCAATCGGTACAAAACATCTGGCTAAGGCTGAAATACTTCTGTGTTTGATATTTGAGCCTTGGTCTATTTTAGGAGTC
ATTACTATTAAAACTTTAAT

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MSTTFYMPPMSMMGPDAIKQLGSELNARNFHKALIVTDKALVDIKLVDRLTEELSAHNIAFAIFDGVKPNPTENNIEQGL
KLLSAEDCDLVISFGGGSSHDCAKGIALVATNGGHIRDYSKGVHLSTKPQLPLVTVNTTAGTASEMTIFAIVTNEKDETK
YPVVDKNLTPIIAVNDSELMVAMPKFLTAATGMDALTHAVEAYVSTAATPITDASAIKAIELISSNLEAVVDNGENREAR
DAMQYGEFLAGMAFSNASLGYVHSMAHQLGGVYDLVHGLCNAILLPHVSRFNAALSTERFADIAKAMGVDSTGMNVAEAA
EAGILAIEALSESVGTAQKLSDLGVKQDKLEFMAINALNDACSLTNPRKASTEEIINIFNQAM

Sequences:

>Translated_383_residues
MSTTFYMPPMSMMGPDAIKQLGSELNARNFHKALIVTDKALVDIKLVDRLTEELSAHNIAFAIFDGVKPNPTENNIEQGL
KLLSAEDCDLVISFGGGSSHDCAKGIALVATNGGHIRDYSKGVHLSTKPQLPLVTVNTTAGTASEMTIFAIVTNEKDETK
YPVVDKNLTPIIAVNDSELMVAMPKFLTAATGMDALTHAVEAYVSTAATPITDASAIKAIELISSNLEAVVDNGENREAR
DAMQYGEFLAGMAFSNASLGYVHSMAHQLGGVYDLVHGLCNAILLPHVSRFNAALSTERFADIAKAMGVDSTGMNVAEAA
EAGILAIEALSESVGTAQKLSDLGVKQDKLEFMAINALNDACSLTNPRKASTEEIINIFNQAM
>Mature_382_residues
STTFYMPPMSMMGPDAIKQLGSELNARNFHKALIVTDKALVDIKLVDRLTEELSAHNIAFAIFDGVKPNPTENNIEQGLK
LLSAEDCDLVISFGGGSSHDCAKGIALVATNGGHIRDYSKGVHLSTKPQLPLVTVNTTAGTASEMTIFAIVTNEKDETKY
PVVDKNLTPIIAVNDSELMVAMPKFLTAATGMDALTHAVEAYVSTAATPITDASAIKAIELISSNLEAVVDNGENREARD
AMQYGEFLAGMAFSNASLGYVHSMAHQLGGVYDLVHGLCNAILLPHVSRFNAALSTERFADIAKAMGVDSTGMNVAEAAE
AGILAIEALSESVGTAQKLSDLGVKQDKLEFMAINALNDACSLTNPRKASTEEIINIFNQAM

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=352, Percent_Identity=26.4204545454545, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI48994951, Length=382, Percent_Identity=55.2356020942408, Blast_Score=429, Evalue=1e-121,
Organism=Escherichia coli, GI1789163, Length=385, Percent_Identity=40.5194805194805, Blast_Score=304, Evalue=8e-84,
Organism=Escherichia coli, GI87082107, Length=380, Percent_Identity=35.5263157894737, Blast_Score=227, Evalue=8e-61,
Organism=Escherichia coli, GI1787493, Length=381, Percent_Identity=33.3333333333333, Blast_Score=195, Evalue=4e-51,
Organism=Escherichia coli, GI1789386, Length=297, Percent_Identity=24.5791245791246, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17537053, Length=274, Percent_Identity=26.6423357664234, Blast_Score=102, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6321181, Length=382, Percent_Identity=47.1204188481675, Blast_Score=357, Evalue=2e-99,
Organism=Drosophila melanogaster, GI24657991, Length=410, Percent_Identity=24.6341463414634, Blast_Score=116, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 40696; Mature: 40565

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTFYMPPMSMMGPDAIKQLGSELNARNFHKALIVTDKALVDIKLVDRLTEELSAHNIA
CCCEEECCCHHHCCHHHHHHHHHHCCCCCHHEEEEEECCHHHHHHHHHHHHHHHHHCCEE
FAIFDGVKPNPTENNIEQGLKLLSAEDCDLVISFGGGSSHDCAKGIALVATNGGHIRDYS
EEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHCCEEEEEECCCCEEHHC
KGVHLSTKPQLPLVTVNTTAGTASEMTIFAIVTNEKDETKYPVVDKNLTPIIAVNDSELM
CCCEECCCCCCCEEEEECCCCCCCCEEEEEEEECCCCCCCCCEECCCCCEEEEECCCCEE
VAMPKFLTAATGMDALTHAVEAYVSTAATPITDASAIKAIELISSNLEAVVDNGENREAR
EEHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHCCCCCCHHH
DAMQYGEFLAGMAFSNASLGYVHSMAHQLGGVYDLVHGLCNAILLPHVSRFNAALSTERF
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
ADIAKAMGVDSTGMNVAEAAEAGILAIEALSESVGTAQKLSDLGVKQDKLEFMAINALND
HHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEEEEHHHH
ACSLTNPRKASTEEIINIFNQAM
HHCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
STTFYMPPMSMMGPDAIKQLGSELNARNFHKALIVTDKALVDIKLVDRLTEELSAHNIA
CCEEECCCHHHCCHHHHHHHHHHCCCCCHHEEEEEECCHHHHHHHHHHHHHHHHHCCEE
FAIFDGVKPNPTENNIEQGLKLLSAEDCDLVISFGGGSSHDCAKGIALVATNGGHIRDYS
EEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHCCEEEEEECCCCEEHHC
KGVHLSTKPQLPLVTVNTTAGTASEMTIFAIVTNEKDETKYPVVDKNLTPIIAVNDSELM
CCCEECCCCCCCEEEEECCCCCCCCEEEEEEEECCCCCCCCCEECCCCCEEEEECCCCEE
VAMPKFLTAATGMDALTHAVEAYVSTAATPITDASAIKAIELISSNLEAVVDNGENREAR
EEHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHCCCCCCHHH
DAMQYGEFLAGMAFSNASLGYVHSMAHQLGGVYDLVHGLCNAILLPHVSRFNAALSTERF
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
ADIAKAMGVDSTGMNVAEAAEAGILAIEALSESVGTAQKLSDLGVKQDKLEFMAINALND
HHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEEEEHHHH
ACSLTNPRKASTEEIINIFNQAM
HHCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]