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The map label for this gene is ilvK [H]

Identifier: 167625869

GI number: 167625869

Start: 4834257

End: 4835348

Strand: Reverse

Name: ilvK [H]

Synonym: Shal_3964

Alternate gene names: 167625869

Gene position: 4835348-4834257 (Counterclockwise)

Preceding gene: 167625870

Following gene: 167625859

Centisome position: 92.51

GC content: 49.27

Gene sequence:

>1092_bases
ATGCAAATAACTTACAACTTAAAACCTGCGTTAGAGCGCCGTACCGAGCAATTCAAGCCTACAAGCAATGTCGGCTTCGG
TAACCTCAGAACTGACCACATGTTTTTAATGGATTATCGCGATGGGCAGTGGTGTGATCCCAGAGTCGTTCCTTATGGCC
CATTTGAAGTTGCACCGGGTGCCATTGCTCTACATTATGGTCAGTCAGTTTTTGAAGGTGCAAAAGCCTTCCAGCACGAA
GACGGCGAAATTTACACCTTCCGCATTGATAAAAATGCCGAACGTTTAAATCGTTCGGCAGACATTCTCTGTATTCCGGC
ATTACCTGAACAGATGCAGATAGATGCCATCAATGCCTTGATTGATGTGGATCGTTTGTGGTTCCCGATGCAAGAGGGCG
CCTGTCTCTATATCCGTCCATTTATCTTTGCTACCGAAGACCGCTTATCGGTGAGTCCGAGTGAGCAATATACCTTCTGC
GTGATGTTGAGCCCTAGTGGCCCCTATTATAGCGACGGTTTCGATAAGGCGATTCGTCTGTTGATCAGCGAGCGTTTTCA
CCGCGCAGTTGCCGGCGGTACCGGTGCCTCTAAGGCGGCGGGTAACTACGCGGCATCGCTAAAGGCGGGTAAGGCTGCTG
CTGAGTATGGTGCCGCGCAGGTGCTGTACTTGGATGCTAACAATAAGCAGATTGAAGAAGTGGGCGCGATGAACCATTTC
CACGTGCTTAAAGACGGCACGATTATTATTCCAAAATTTACCGACACCATCTTAAAGTCGATTACCTCACAATCTATTCT
TGATTTGGGCGGGCTGCTGGGCTGCGAAGTACGCCAAGAGACGGTGATGTTGGATCAGTTTATTAGCGATATCGAGTCTG
GTGAGATCATCGAAGCGGGTGGTTTTGGTACTGCGGCTGTCGTATCGCCAGTTGGCTCTTATATCTTCGAAGATAACCGC
ATTGTCACGGTCGGAGATGGCGAAGTAGGTGAGCACACTAAGCGGATCTATAAGGTGTTAACCGAGATCCAGAAAGGTCA
TATTCAAGGGCCAGAAGGCTGGGTGCAGCACGTTAAGCGTATGCAGGGCTAA

Upstream 100 bases:

>100_bases
GTTAATACGCTTATTGAAGATCTTGAGGCTAGCCCCCGTTTTGCTTGACTTTTATATGACCACTGATAGGCTGCTCAGTC
AGTAATCAAGGTGGTATACA

Downstream 100 bases:

>100_bases
CAAGCTATTTTCTAAAGGCTAAGCTTAGCTCACTTAGCTGAATGCAAAAGGCTCCTAATTAGGAGCCTTTTTTATGGATG
TTTTTTAAAGCGTGACAATA

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT 2; Vegetative protein 85; VEG85 [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MQITYNLKPALERRTEQFKPTSNVGFGNLRTDHMFLMDYRDGQWCDPRVVPYGPFEVAPGAIALHYGQSVFEGAKAFQHE
DGEIYTFRIDKNAERLNRSADILCIPALPEQMQIDAINALIDVDRLWFPMQEGACLYIRPFIFATEDRLSVSPSEQYTFC
VMLSPSGPYYSDGFDKAIRLLISERFHRAVAGGTGASKAAGNYAASLKAGKAAAEYGAAQVLYLDANNKQIEEVGAMNHF
HVLKDGTIIIPKFTDTILKSITSQSILDLGGLLGCEVRQETVMLDQFISDIESGEIIEAGGFGTAAVVSPVGSYIFEDNR
IVTVGDGEVGEHTKRIYKVLTEIQKGHIQGPEGWVQHVKRMQG

Sequences:

>Translated_363_residues
MQITYNLKPALERRTEQFKPTSNVGFGNLRTDHMFLMDYRDGQWCDPRVVPYGPFEVAPGAIALHYGQSVFEGAKAFQHE
DGEIYTFRIDKNAERLNRSADILCIPALPEQMQIDAINALIDVDRLWFPMQEGACLYIRPFIFATEDRLSVSPSEQYTFC
VMLSPSGPYYSDGFDKAIRLLISERFHRAVAGGTGASKAAGNYAASLKAGKAAAEYGAAQVLYLDANNKQIEEVGAMNHF
HVLKDGTIIIPKFTDTILKSITSQSILDLGGLLGCEVRQETVMLDQFISDIESGEIIEAGGFGTAAVVSPVGSYIFEDNR
IVTVGDGEVGEHTKRIYKVLTEIQKGHIQGPEGWVQHVKRMQG
>Mature_363_residues
MQITYNLKPALERRTEQFKPTSNVGFGNLRTDHMFLMDYRDGQWCDPRVVPYGPFEVAPGAIALHYGQSVFEGAKAFQHE
DGEIYTFRIDKNAERLNRSADILCIPALPEQMQIDAINALIDVDRLWFPMQEGACLYIRPFIFATEDRLSVSPSEQYTFC
VMLSPSGPYYSDGFDKAIRLLISERFHRAVAGGTGASKAAGNYAASLKAGKAAAEYGAAQVLYLDANNKQIEEVGAMNHF
HVLKDGTIIIPKFTDTILKSITSQSILDLGGLLGCEVRQETVMLDQFISDIESGEIIEAGGFGTAAVVSPVGSYIFEDNR
IVTVGDGEVGEHTKRIYKVLTEIQKGHIQGPEGWVQHVKRMQG

Specific function: Transaminates branched-chain amino acids and ketoglutarate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI50658084, Length=334, Percent_Identity=34.4311377245509, Blast_Score=195, Evalue=6e-50,
Organism=Homo sapiens, GI296010904, Length=334, Percent_Identity=35.0299401197605, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI296010906, Length=334, Percent_Identity=35.0299401197605, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI38176287, Length=334, Percent_Identity=35.0299401197605, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI258614015, Length=285, Percent_Identity=34.7368421052632, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI296010902, Length=333, Percent_Identity=31.2312312312312, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI296010900, Length=333, Percent_Identity=31.2312312312312, Blast_Score=147, Evalue=1e-35,
Organism=Escherichia coli, GI48994963, Length=321, Percent_Identity=30.5295950155763, Blast_Score=116, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17568601, Length=358, Percent_Identity=31.5642458100559, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17565728, Length=352, Percent_Identity=32.9545454545455, Blast_Score=166, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6322608, Length=343, Percent_Identity=34.402332361516, Blast_Score=182, Evalue=8e-47,
Organism=Saccharomyces cerevisiae, GI6322002, Length=361, Percent_Identity=32.409972299169, Blast_Score=181, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24641779, Length=349, Percent_Identity=33.810888252149, Blast_Score=181, Evalue=6e-46,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005786 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 40155; Mature: 40155

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQITYNLKPALERRTEQFKPTSNVGFGNLRTDHMFLMDYRDGQWCDPRVVPYGPFEVAPG
CEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCC
AIALHYGQSVFEGAKAFQHEDGEIYTFRIDKNAERLNRSADILCIPALPEQMQIDAINAL
EEEEECCHHHHHHHHHHCCCCCCEEEEEECCCHHHCCCCCCEEEECCCCCHHHHHHHHHH
IDVDRLWFPMQEGACLYIRPFIFATEDRLSVSPSEQYTFCVMLSPSGPYYSDGFDKAIRL
HHHHHHCCCCCCCCEEEEEEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHH
LISERFHRAVAGGTGASKAAGNYAASLKAGKAAAEYGAAQVLYLDANNKQIEEVGAMNHF
HHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHCCCEEEEEEECCCCHHHHHCCCCCE
HVLKDGTIIIPKFTDTILKSITSQSILDLGGLLGCEVRQETVMLDQFISDIESGEIIEAG
EEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEC
GFGTAAVVSPVGSYIFEDNRIVTVGDGEVGEHTKRIYKVLTEIQKGHIQGPEGWVQHVKR
CCCHHHHHHHHHHHEECCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
MQG
HCC
>Mature Secondary Structure
MQITYNLKPALERRTEQFKPTSNVGFGNLRTDHMFLMDYRDGQWCDPRVVPYGPFEVAPG
CEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCC
AIALHYGQSVFEGAKAFQHEDGEIYTFRIDKNAERLNRSADILCIPALPEQMQIDAINAL
EEEEECCHHHHHHHHHHCCCCCCEEEEEECCCHHHCCCCCCEEEECCCCCHHHHHHHHHH
IDVDRLWFPMQEGACLYIRPFIFATEDRLSVSPSEQYTFCVMLSPSGPYYSDGFDKAIRL
HHHHHHCCCCCCCCEEEEEEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHH
LISERFHRAVAGGTGASKAAGNYAASLKAGKAAAEYGAAQVLYLDANNKQIEEVGAMNHF
HHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHCCCEEEEEEECCCCHHHHHCCCCCE
HVLKDGTIIIPKFTDTILKSITSQSILDLGGLLGCEVRQETVMLDQFISDIESGEIIEAG
EEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEC
GFGTAAVVSPVGSYIFEDNRIVTVGDGEVGEHTKRIYKVLTEIQKGHIQGPEGWVQHVKR
CCCHHHHHHHHHHHEECCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
MQG
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 7934828; 9298659 [H]