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The map label for this gene is aer [H]

Identifier: 167625858

GI number: 167625858

Start: 4820618

End: 4822171

Strand: Reverse

Name: aer [H]

Synonym: Shal_3953

Alternate gene names: 167625858

Gene position: 4822171-4820618 (Counterclockwise)

Preceding gene: 167625859

Following gene: 167625854

Centisome position: 92.26

GC content: 45.05

Gene sequence:

>1554_bases
ATGGACGAAGAGTACCAGTATCCCGCCAATTACAATTTAATCTCAATCACGTCTCCTTCTAGTCATATTAAATATGCCAG
CCCGCATTTTTCTGAAGTAGCGGGATTTGCAGATGGTGAGCTTGTTGGTCTTCCTCATAATGTTGTTAGACATCCGGACA
TGCCAAAGGCCGCGTTTAAAGATCTTTGGGGTCACTTGCAGAGTGGCAACCATTGGATGGGAATGGTGAAAAACAGCCGT
AAGGGCGGAGGTTATTATTGGGTGGATGCATTCGCATCGCCGATAAAAAACAATGGTGAAATTGTTGAGATGCAATCGGT
GCGCTTTAAGCCTGAGCGTATTCATGTCACTAGAGCCGAGGCGATATATAAGCAGCTCTCAAACGACAAAAAACCCTTTC
GTTTAAGCATCGGCTTGAGAACAAGGCTTTGGCAGCGCAGCGCCTTTTTCTATGGCATCGCGGCACTTGTCTCGTATGCG
ATTGCGATGTTTTCCCAAAATACCGCTATCACGCTGGCATCCTTCTTTGTGATGGCGACTCTGATTAGCTATCTGTTAAC
TCGTCCCTTAGAGCGACTCGCAAAAGAGTCCCGTAAAGAATTTAATAACCCGCTGATGGAGTTAATTTACACGGGCAAGG
TTAATGATTTTTCTGAGATAGAGTTGGCAATGAAAATGCGCAAGCAACATGTTAAGGCATTGATTGGTCGGGTCAATATC
TCGGTGATGGAGGCCTGTGATAAGACCTTAGATAACGCAAAGTTAGCCACAGAAAACAACCATAAAGTGACTGAGCACTT
GAACACACAGAAAACGGAAATTGAAATGGTGGCCACGGCAGTCAATGAGATGCAGGCGGCGTCGACTGAAATCTCACAAA
ATGCTCAGGGTACTGCCGAAGCGACAATGCAGACTCAAACGACCATGTCAGATAACTTGGAGTGCATTAACCAGGTTAAT
AAGTCGATGCTGGAGCTAGTGGAGGAGTTGGCTTCAATTTCTAGTACCGTGGTATCACTCGATAAGCAGACTCAGCAAAT
CAGTTCGGTGATCGACGTGATTAATGGCATTGCCGAACAAACCAATTTATTAGCATTGAATGCGGCGATTGAGGCGGCTC
GAGCCGGGGATTCTGGCCGTGGTTTTGCGGTAGTGTCTGATGAGGTGCGTACCTTAGCCCAGCGGACTCAAGTGGCAACA
ACGGAGATCCAGACCGCGATAGAACAGATCCAAAATAATAGTCAAGTTGCGGTTAAGTCACTAGAGGTCGGCAATGACAA
ATCGAGCAAGACGGTCGATATCATCAATACATCACTGGCTAAAATTGGTGAATTAGAAGAACTCATAGAGGGCATTGTGG
AACGTAATCAGCAAATTGCCGTTGCGATTGAAGAACAAGTGTATGTCTGTAATGAAGTGAACACCAATGTGCAGATGGTC
AATTGTAAGGTGTCAGAATCTTATGATCTTATTACCGTTACCAACACTTTAAACCAAGAGGTTGAAAGCAGCACCAGTGA
CCTATCCGATACGATTAGAAATTTTAATATGTAG

Upstream 100 bases:

>100_bases
GAGAGGATGAAAAAAAAAGTCATTATTTCGATGGAATGTGAATATTGATACTACACTGAACGGTAGTTTTGATTTATGCC
ATTAAATAAAGGATTATGTT

Downstream 100 bases:

>100_bases
TCTTGCGGGCTAGTGCCTGAAACGGATTGATATTAAAAGGTGCTTAGCTGATGGCTAAACACCTTTTTTATTGGTAAATA
CTAGAAGTAAAACCTAGATT

Product: Pas/Pac sensor containing methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MDEEYQYPANYNLISITSPSSHIKYASPHFSEVAGFADGELVGLPHNVVRHPDMPKAAFKDLWGHLQSGNHWMGMVKNSR
KGGGYYWVDAFASPIKNNGEIVEMQSVRFKPERIHVTRAEAIYKQLSNDKKPFRLSIGLRTRLWQRSAFFYGIAALVSYA
IAMFSQNTAITLASFFVMATLISYLLTRPLERLAKESRKEFNNPLMELIYTGKVNDFSEIELAMKMRKQHVKALIGRVNI
SVMEACDKTLDNAKLATENNHKVTEHLNTQKTEIEMVATAVNEMQAASTEISQNAQGTAEATMQTQTTMSDNLECINQVN
KSMLELVEELASISSTVVSLDKQTQQISSVIDVINGIAEQTNLLALNAAIEAARAGDSGRGFAVVSDEVRTLAQRTQVAT
TEIQTAIEQIQNNSQVAVKSLEVGNDKSSKTVDIINTSLAKIGELEELIEGIVERNQQIAVAIEEQVYVCNEVNTNVQMV
NCKVSESYDLITVTNTLNQEVESSTSDLSDTIRNFNM

Sequences:

>Translated_517_residues
MDEEYQYPANYNLISITSPSSHIKYASPHFSEVAGFADGELVGLPHNVVRHPDMPKAAFKDLWGHLQSGNHWMGMVKNSR
KGGGYYWVDAFASPIKNNGEIVEMQSVRFKPERIHVTRAEAIYKQLSNDKKPFRLSIGLRTRLWQRSAFFYGIAALVSYA
IAMFSQNTAITLASFFVMATLISYLLTRPLERLAKESRKEFNNPLMELIYTGKVNDFSEIELAMKMRKQHVKALIGRVNI
SVMEACDKTLDNAKLATENNHKVTEHLNTQKTEIEMVATAVNEMQAASTEISQNAQGTAEATMQTQTTMSDNLECINQVN
KSMLELVEELASISSTVVSLDKQTQQISSVIDVINGIAEQTNLLALNAAIEAARAGDSGRGFAVVSDEVRTLAQRTQVAT
TEIQTAIEQIQNNSQVAVKSLEVGNDKSSKTVDIINTSLAKIGELEELIEGIVERNQQIAVAIEEQVYVCNEVNTNVQMV
NCKVSESYDLITVTNTLNQEVESSTSDLSDTIRNFNM
>Mature_517_residues
MDEEYQYPANYNLISITSPSSHIKYASPHFSEVAGFADGELVGLPHNVVRHPDMPKAAFKDLWGHLQSGNHWMGMVKNSR
KGGGYYWVDAFASPIKNNGEIVEMQSVRFKPERIHVTRAEAIYKQLSNDKKPFRLSIGLRTRLWQRSAFFYGIAALVSYA
IAMFSQNTAITLASFFVMATLISYLLTRPLERLAKESRKEFNNPLMELIYTGKVNDFSEIELAMKMRKQHVKALIGRVNI
SVMEACDKTLDNAKLATENNHKVTEHLNTQKTEIEMVATAVNEMQAASTEISQNAQGTAEATMQTQTTMSDNLECINQVN
KSMLELVEELASISSTVVSLDKQTQQISSVIDVINGIAEQTNLLALNAAIEAARAGDSGRGFAVVSDEVRTLAQRTQVAT
TEIQTAIEQIQNNSQVAVKSLEVGNDKSSKTVDIINTSLAKIGELEELIEGIVERNQQIAVAIEEQVYVCNEVNTNVQMV
NCKVSESYDLITVTNTLNQEVESSTSDLSDTIRNFNM

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=430, Percent_Identity=32.5581395348837, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI2367378, Length=239, Percent_Identity=30.9623430962343, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1787690, Length=362, Percent_Identity=24.3093922651934, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788194, Length=109, Percent_Identity=44.0366972477064, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788195, Length=167, Percent_Identity=35.3293413173653, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 57425; Mature: 57425

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEEYQYPANYNLISITSPSSHIKYASPHFSEVAGFADGELVGLPHNVVRHPDMPKAAFK
CCCCCCCCCCCCEEEECCCCCCCEECCCCHHHHCCCCCCCEECCCHHHHCCCCCCHHHHH
DLWGHLQSGNHWMGMVKNSRKGGGYYWVDAFASPIKNNGEIVEMQSVRFKPERIHVTRAE
HHHHHHCCCCCEEEEECCCCCCCCEEEHHHHHCCCCCCCCEEEECCCCCCCHHEEEHHHH
AIYKQLSNDKKPFRLSIGLRTRLWQRSAFFYGIAALVSYAIAMFSQNTAITLASFFVMAT
HHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LISYLLTRPLERLAKESRKEFNNPLMELIYTGKVNDFSEIELAMKMRKQHVKALIGRVNI
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
SVMEACDKTLDNAKLATENNHKVTEHLNTQKTEIEMVATAVNEMQAASTEISQNAQGTAE
HHHHHHHHHHCCCEECCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
ATMQTQTTMSDNLECINQVNKSMLELVEELASISSTVVSLDKQTQQISSVIDVINGIAEQ
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TNLLALNAAIEAARAGDSGRGFAVVSDEVRTLAQRTQVATTEIQTAIEQIQNNSQVAVKS
CCEEEEHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
LEVGNDKSSKTVDIINTSLAKIGELEELIEGIVERNQQIAVAIEEQVYVCNEVNTNVQMV
EECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEECCCCCEEEE
NCKVSESYDLITVTNTLNQEVESSTSDLSDTIRNFNM
EEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDEEYQYPANYNLISITSPSSHIKYASPHFSEVAGFADGELVGLPHNVVRHPDMPKAAFK
CCCCCCCCCCCCEEEECCCCCCCEECCCCHHHHCCCCCCCEECCCHHHHCCCCCCHHHHH
DLWGHLQSGNHWMGMVKNSRKGGGYYWVDAFASPIKNNGEIVEMQSVRFKPERIHVTRAE
HHHHHHCCCCCEEEEECCCCCCCCEEEHHHHHCCCCCCCCEEEECCCCCCCHHEEEHHHH
AIYKQLSNDKKPFRLSIGLRTRLWQRSAFFYGIAALVSYAIAMFSQNTAITLASFFVMAT
HHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LISYLLTRPLERLAKESRKEFNNPLMELIYTGKVNDFSEIELAMKMRKQHVKALIGRVNI
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
SVMEACDKTLDNAKLATENNHKVTEHLNTQKTEIEMVATAVNEMQAASTEISQNAQGTAE
HHHHHHHHHHCCCEECCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
ATMQTQTTMSDNLECINQVNKSMLELVEELASISSTVVSLDKQTQQISSVIDVINGIAEQ
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TNLLALNAAIEAARAGDSGRGFAVVSDEVRTLAQRTQVATTEIQTAIEQIQNNSQVAVKS
CCEEEEHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
LEVGNDKSSKTVDIINTSLAKIGELEELIEGIVERNQQIAVAIEEQVYVCNEVNTNVQMV
EECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEECCCCCEEEE
NCKVSESYDLITVTNTLNQEVESSTSDLSDTIRNFNM
EEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]