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The map label for this gene is xerC [H]

Identifier: 167625815

GI number: 167625815

Start: 4746437

End: 4747348

Strand: Reverse

Name: xerC [H]

Synonym: Shal_3910

Alternate gene names: 167625815

Gene position: 4747348-4746437 (Counterclockwise)

Preceding gene: 167625816

Following gene: 167625814

Centisome position: 90.83

GC content: 47.92

Gene sequence:

>912_bases
ATGGCTGACGAAGCGTTATCGGATAATTCAGTTTGGTTGAGCAGTTTTGAGCGTTACCTGCGCACTGAGCGTCAAGTTTC
AGCTTATACGGTGCGTAACTACCTGTTTGAGCTAAAGCGAGTCGAAAAGCTATTTAGCGAGACTGAGTCATGGTTGTCAC
AGCAACATGACTCCCTGCAGGCTATTTTAGCTAAATTGCACCGCAAGGGCTTAAGCCCACGCTCCTTGTCATTAACTCTC
TCCTCTTTAAAGCAGTTCTATGAGTTTTTACTTAGAGAGCAACAGTTAAAAATTAATCCGGCTATCAGCCTTACCGCACC
CAAGCAGGGCAAGCCTTTGCCTAAGAATATGGATGTCGACTCTGTATCACATCTACTTGATATCGACGCTAACGATCCAC
TAAGTTTTCGAGATAAAGCCATCATGGAGCTGTTTTACTCCTCGGGGCTGCGTCTTGGAGAACTCGCTGCGCTTAATGCT
GCCGATATTCAGTTTTCAGAGGCGCAAGTTAAAGTGCTGGGTAAGGGCAGCAAAGAGCGGATCGTGCCCATTGGTAAGTT
GGCATTAGCCGCTATTACCCAGTGGCTAGAGATTAAGCGAGATATCGCCTGTGAAGGCGATGCGTTATTTGTCACAGCAA
AGGGTAAGCGTTTGGCGCATAGAAGTATTCAAGCGCGTTTAGCCAAGTGGGGACAAGAGCAAGCCATAGGCATGAAGGTG
CACCCGCATAAATTACGCCACTCTTTTGCGACGCATATGCTCGAGTCCAGTGCCGATCTACGTGCGGTGCAGGAGCTGTT
AGGTCACGCCAACTTGTCGACTACCCAAGTTTATACCAGTCTAGACTTTCAACATCTTGCCAAGGTATACGACGGTGCAC
ATCCAAGAGCGAGAAAAAGAGGCAACAGCTGA

Upstream 100 bases:

>100_bases
AGATCCTATGCACTTTCATCCAGAGATGGATCATCTTCTTCTATCACAGCTTAAACAGTTACTTGATCACCAGCTGACCA
AAATCTAATAGCGAGGCTCT

Downstream 100 bases:

>100_bases
TGAAGATCTTTATTCGCCCACAGCCCTTTGAAGCCATTAGCTTCGACTTAGATGATACCCTCTATGATAATCGGCCAATC
ATTCGAAACGCCGAAGCCGC

Product: tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MADEALSDNSVWLSSFERYLRTERQVSAYTVRNYLFELKRVEKLFSETESWLSQQHDSLQAILAKLHRKGLSPRSLSLTL
SSLKQFYEFLLREQQLKINPAISLTAPKQGKPLPKNMDVDSVSHLLDIDANDPLSFRDKAIMELFYSSGLRLGELAALNA
ADIQFSEAQVKVLGKGSKERIVPIGKLALAAITQWLEIKRDIACEGDALFVTAKGKRLAHRSIQARLAKWGQEQAIGMKV
HPHKLRHSFATHMLESSADLRAVQELLGHANLSTTQVYTSLDFQHLAKVYDGAHPRARKRGNS

Sequences:

>Translated_303_residues
MADEALSDNSVWLSSFERYLRTERQVSAYTVRNYLFELKRVEKLFSETESWLSQQHDSLQAILAKLHRKGLSPRSLSLTL
SSLKQFYEFLLREQQLKINPAISLTAPKQGKPLPKNMDVDSVSHLLDIDANDPLSFRDKAIMELFYSSGLRLGELAALNA
ADIQFSEAQVKVLGKGSKERIVPIGKLALAAITQWLEIKRDIACEGDALFVTAKGKRLAHRSIQARLAKWGQEQAIGMKV
HPHKLRHSFATHMLESSADLRAVQELLGHANLSTTQVYTSLDFQHLAKVYDGAHPRARKRGNS
>Mature_302_residues
ADEALSDNSVWLSSFERYLRTERQVSAYTVRNYLFELKRVEKLFSETESWLSQQHDSLQAILAKLHRKGLSPRSLSLTLS
SLKQFYEFLLREQQLKINPAISLTAPKQGKPLPKNMDVDSVSHLLDIDANDPLSFRDKAIMELFYSSGLRLGELAALNAA
DIQFSEAQVKVLGKGSKERIVPIGKLALAAITQWLEIKRDIACEGDALFVTAKGKRLAHRSIQARLAKWGQEQAIGMKVH
PHKLRHSFATHMLESSADLRAVQELLGHANLSTTQVYTSLDFQHLAKVYDGAHPRARKRGNS

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=288, Percent_Identity=52.0833333333333, Blast_Score=301, Evalue=3e-83,
Organism=Escherichia coli, GI1789261, Length=294, Percent_Identity=35.7142857142857, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1790768, Length=158, Percent_Identity=27.2151898734177, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790767, Length=180, Percent_Identity=25.5555555555556, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34116; Mature: 33984

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADEALSDNSVWLSSFERYLRTERQVSAYTVRNYLFELKRVEKLFSETESWLSQQHDSLQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AILAKLHRKGLSPRSLSLTLSSLKQFYEFLLREQQLKINPAISLTAPKQGKPLPKNMDVD
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCEEEECCCCCCCCCCCCCHH
SVSHLLDIDANDPLSFRDKAIMELFYSSGLRLGELAALNAADIQFSEAQVKVLGKGSKER
HHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCHHCCEECHHHEEEECCCCCCC
IVPIGKLALAAITQWLEIKRDIACEGDALFVTAKGKRLAHRSIQARLAKWGQEQAIGMKV
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCHHHCCCCCC
HPHKLRHSFATHMLESSADLRAVQELLGHANLSTTQVYTSLDFQHLAKVYDGAHPRARKR
CHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHCCCCCHHHCC
GNS
CCC
>Mature Secondary Structure 
ADEALSDNSVWLSSFERYLRTERQVSAYTVRNYLFELKRVEKLFSETESWLSQQHDSLQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AILAKLHRKGLSPRSLSLTLSSLKQFYEFLLREQQLKINPAISLTAPKQGKPLPKNMDVD
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCEEEECCCCCCCCCCCCCHH
SVSHLLDIDANDPLSFRDKAIMELFYSSGLRLGELAALNAADIQFSEAQVKVLGKGSKER
HHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCHHCCEECHHHEEEECCCCCCC
IVPIGKLALAAITQWLEIKRDIACEGDALFVTAKGKRLAHRSIQARLAKWGQEQAIGMKV
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCHHHCCCCCC
HPHKLRHSFATHMLESSADLRAVQELLGHANLSTTQVYTSLDFQHLAKVYDGAHPRARKR
CHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHCCCCCHHHCC
GNS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]