Click here to switch to the map view.

The map label for this gene is rnr [H]

Identifier: 167625584

GI number: 167625584

Start: 4478957

End: 4481440

Strand: Reverse

Name: rnr [H]

Synonym: Shal_3678

Alternate gene names: 167625584

Gene position: 4481440-4478957 (Counterclockwise)

Preceding gene: 167625585

Following gene: 167625583

Centisome position: 85.74

GC content: 48.55

Gene sequence:

>2484_bases
ATGATACAAGATCCGCATATTAAGCGTGAGCAAGAAAAATACGAAAACCCTATTCCAAGTCGCGAGTATATTTTAGATTA
CTTGCGCTCACAAAAGTCCCCGTTAACCCGAGAGCATATTGCTACTGCTTTAAAAATTGAAGGTGAAGAGCAACTAGAAG
CTATTCGTCGTCGCCTGCGTGCGATGGAGCGTGATGGTGAGTTAGTCTTTACCCGTGGCCAGTCATATGGCTTGCCAGAG
AGAATGGACCTGTTAACTGGTACTGTGATTGGTCACCGAGATGGCTTTGGATTTCTAAAGCTAGAAGAGGGAGGGGACGA
CCTTTATATCAACAACCGTGACATGCTGATGTATTTCCACGGTGACAGGGTCCTTGCACAAAAAGCGGGCGTCGATCGTA
AGGGTCGCCGTGAAGCGCGTATTGTACGTTTGGTAGAAGAGCGTAACGCCGCATTAGTTGGTCGCTTTCATCTAGATGCT
GGCATGGGCTTTGTGATTGCCGATGACCGCCGCATCACGCAAGAGATTTTAGTTCCGGAAGAAGATCGCAAGGGCGCGCG
CCAAGGCGATATCGTGGTGCTTGAGCTGACTCGTCGACCGGGCCGTTATGTTAAAGCGGCTGGTAAAGTGACGGAGGTGC
TCGGTAAAGAGATGGCTCCGGGTATGGAGATTGAGATTGCACTGCGCAATTACGATCTGCCGCACACTTGGTCAGGCTTG
ATAGAGAAGAAGCTGCGTAAAATTCCTGATGAAGTGACCGAGGCCGATAAAGAGGGCCGCGTCGATCTACGTCAGTTGCC
GCTGGTCACTATCGATGGTGAAGATGCGCGTGACTTTGACGATGCCGTTTACGCTGAGAAGAAAAAGTCTGGCGGCTGGC
GCCTGTGGGTGGCGATTGCAGACGTAAGTCATTACGTTCGTACAGAGTCGGCACTGGATAAAGAAGCGCGCGCACGTGGT
AACTCGGTGTATTTCCCATCGCAAGTTATCCCTATGCTGCCTGAGAAGATCTCTAATGGTCTGTGCTCATTGATGCCAAA
AGTCGATCGTTTGTGCATGGTAGCTGAGATGACTATCTCGGCAGCAGGTAAGCTATCGGGCTATAAGTTTTATCCGGCAG
TGATGCATTCTCATGCGCGTTTAACCTATACCCAGGTTGCCGATATGCTTGAGGGCGGTGAGGTAAGCGATGAGCTTAAG
CCAATATTTCCGCACCTGCAGACATTACAATCACTGTACCTGACATTAGATGAAACTCGCGCCGAACGTGGTGCAATTGC
TTTTGAAACCACTGAAACCCAGTTTATCTTCAATGAGCAACGTAAGATCGACAAGATTGTGCCGCGCAGCCGTAATCAAG
CGCATAAAATTATCGAAGAATGCATGATCTTAGCTAACGTTGCGTCAGCTAAATTTGTTAAAAAGCACAAAGGTGAAGTG
TTATACCGTGTGCATGAGTCACCGTCAGAGCAGAAGCTAACCAACTTTAAAGATTTCCTTAAAGAACGTGGCTTGACGAT
GGAAGGTGGTTTAGAGCCTGAGCCTAAAGATTACCAAGCGGTAATGGAGCAGGTTGCTGATAGACCCGATGCTGAGCTGA
TTCAGGTGATGTTGCTGCGCTCAATGCGCCAAGCGACTTATACACCAGATAATGAAGGTCACTTTGGTTTGGCGCTTGAG
GAGTATTCGCACTTCACGTCGCCAATCCGTCGTTACCCAGATTTGATCTTGCACCGAGTGATCCGTTACCTACTTGCTAA
GCAAGAAAATACAGCATTAACCGACCAGTGGACTGCCGATGGTGGTTACCACTACAAGATTGAAGAGCTAGATCAGCTTG
GTGAAGAGTGTTCGACTACTGAGCGCCGAGCTGATGAAGCGACCCGTGATGTGAATGACTGGCTTAAATGCGAGTTTATG
CAAGATCACGTTGGTGATACTTTTGAGGCGGTTATTGCCTCTGTGACACATTTTGGCATGTTCGTGCGCTTAAATGACCT
GTTTATCGATGGTCTAGTGCATATCTCAAGCCTAGGCAGTGATTATTACCAATATGATAATATGCGCCAGCGTTTAGTGG
GCGAGGCCTCGGGTCAGGTTTATCAGATTGGTGATACGGTAACGGTTAAAGTTGCTGGCGTGAACCTCGATGACCGTCAA
ATTGACTTGATGATGGAAGGCGACTCTGCAGGTGGTAAACGTCGTAGACCAACTAAGCCGTTAACCGCGCGTGAGCGAGT
GAATCGCGAAGGTGCAAAGCTTGGGGCTAAGCGTGAGTCTTCTAGAGGTAAAGGCGCAGAGGGTGACTCTGAGTCTAAGT
CTGAGACAAAACGTAAGCCGAGTCGTTCAGGTGCTAAGTCGAGCGGCGGTAAATATAAGAGCGGCAGCAGCGCTGCAGCT
AAAAAGACTAAGACAAAAGCTTCGGCAAAAAAATCTTCAGCAAGTAAAGCTAAGTCAGCCAAGCGTAAAGCGAGTAAGAA
ATAG

Upstream 100 bases:

>100_bases
AGATGCCGCCCAGCGCAGTCGCTAGGGCAAAGAAAGAGCACCTTAGAACGCAACAATAAGCATGGTCTAGAGATGGCCAT
GTCACTAATTTGGAAAGTGA

Downstream 100 bases:

>100_bases
ATGAAAAAGCAAGATATGACCTTTGGGTTACACGCGGTTGAAGCCGTACTTAAAAACAGTCCTGAGCGTGTCATTGAGAT
GTGGGTGCTTCAAGGTCGTG

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R [H]

Number of amino acids: Translated: 827; Mature: 827

Protein sequence:

>827_residues
MIQDPHIKREQEKYENPIPSREYILDYLRSQKSPLTREHIATALKIEGEEQLEAIRRRLRAMERDGELVFTRGQSYGLPE
RMDLLTGTVIGHRDGFGFLKLEEGGDDLYINNRDMLMYFHGDRVLAQKAGVDRKGRREARIVRLVEERNAALVGRFHLDA
GMGFVIADDRRITQEILVPEEDRKGARQGDIVVLELTRRPGRYVKAAGKVTEVLGKEMAPGMEIEIALRNYDLPHTWSGL
IEKKLRKIPDEVTEADKEGRVDLRQLPLVTIDGEDARDFDDAVYAEKKKSGGWRLWVAIADVSHYVRTESALDKEARARG
NSVYFPSQVIPMLPEKISNGLCSLMPKVDRLCMVAEMTISAAGKLSGYKFYPAVMHSHARLTYTQVADMLEGGEVSDELK
PIFPHLQTLQSLYLTLDETRAERGAIAFETTETQFIFNEQRKIDKIVPRSRNQAHKIIEECMILANVASAKFVKKHKGEV
LYRVHESPSEQKLTNFKDFLKERGLTMEGGLEPEPKDYQAVMEQVADRPDAELIQVMLLRSMRQATYTPDNEGHFGLALE
EYSHFTSPIRRYPDLILHRVIRYLLAKQENTALTDQWTADGGYHYKIEELDQLGEECSTTERRADEATRDVNDWLKCEFM
QDHVGDTFEAVIASVTHFGMFVRLNDLFIDGLVHISSLGSDYYQYDNMRQRLVGEASGQVYQIGDTVTVKVAGVNLDDRQ
IDLMMEGDSAGGKRRRPTKPLTARERVNREGAKLGAKRESSRGKGAEGDSESKSETKRKPSRSGAKSSGGKYKSGSSAAA
KKTKTKASAKKSSASKAKSAKRKASKK

Sequences:

>Translated_827_residues
MIQDPHIKREQEKYENPIPSREYILDYLRSQKSPLTREHIATALKIEGEEQLEAIRRRLRAMERDGELVFTRGQSYGLPE
RMDLLTGTVIGHRDGFGFLKLEEGGDDLYINNRDMLMYFHGDRVLAQKAGVDRKGRREARIVRLVEERNAALVGRFHLDA
GMGFVIADDRRITQEILVPEEDRKGARQGDIVVLELTRRPGRYVKAAGKVTEVLGKEMAPGMEIEIALRNYDLPHTWSGL
IEKKLRKIPDEVTEADKEGRVDLRQLPLVTIDGEDARDFDDAVYAEKKKSGGWRLWVAIADVSHYVRTESALDKEARARG
NSVYFPSQVIPMLPEKISNGLCSLMPKVDRLCMVAEMTISAAGKLSGYKFYPAVMHSHARLTYTQVADMLEGGEVSDELK
PIFPHLQTLQSLYLTLDETRAERGAIAFETTETQFIFNEQRKIDKIVPRSRNQAHKIIEECMILANVASAKFVKKHKGEV
LYRVHESPSEQKLTNFKDFLKERGLTMEGGLEPEPKDYQAVMEQVADRPDAELIQVMLLRSMRQATYTPDNEGHFGLALE
EYSHFTSPIRRYPDLILHRVIRYLLAKQENTALTDQWTADGGYHYKIEELDQLGEECSTTERRADEATRDVNDWLKCEFM
QDHVGDTFEAVIASVTHFGMFVRLNDLFIDGLVHISSLGSDYYQYDNMRQRLVGEASGQVYQIGDTVTVKVAGVNLDDRQ
IDLMMEGDSAGGKRRRPTKPLTARERVNREGAKLGAKRESSRGKGAEGDSESKSETKRKPSRSGAKSSGGKYKSGSSAAA
KKTKTKASAKKSSASKAKSAKRKASKK
>Mature_827_residues
MIQDPHIKREQEKYENPIPSREYILDYLRSQKSPLTREHIATALKIEGEEQLEAIRRRLRAMERDGELVFTRGQSYGLPE
RMDLLTGTVIGHRDGFGFLKLEEGGDDLYINNRDMLMYFHGDRVLAQKAGVDRKGRREARIVRLVEERNAALVGRFHLDA
GMGFVIADDRRITQEILVPEEDRKGARQGDIVVLELTRRPGRYVKAAGKVTEVLGKEMAPGMEIEIALRNYDLPHTWSGL
IEKKLRKIPDEVTEADKEGRVDLRQLPLVTIDGEDARDFDDAVYAEKKKSGGWRLWVAIADVSHYVRTESALDKEARARG
NSVYFPSQVIPMLPEKISNGLCSLMPKVDRLCMVAEMTISAAGKLSGYKFYPAVMHSHARLTYTQVADMLEGGEVSDELK
PIFPHLQTLQSLYLTLDETRAERGAIAFETTETQFIFNEQRKIDKIVPRSRNQAHKIIEECMILANVASAKFVKKHKGEV
LYRVHESPSEQKLTNFKDFLKERGLTMEGGLEPEPKDYQAVMEQVADRPDAELIQVMLLRSMRQATYTPDNEGHFGLALE
EYSHFTSPIRRYPDLILHRVIRYLLAKQENTALTDQWTADGGYHYKIEELDQLGEECSTTERRADEATRDVNDWLKCEFM
QDHVGDTFEAVIASVTHFGMFVRLNDLFIDGLVHISSLGSDYYQYDNMRQRLVGEASGQVYQIGDTVTVKVAGVNLDDRQ
IDLMMEGDSAGGKRRRPTKPLTARERVNREGAKLGAKRESSRGKGAEGDSESKSETKRKPSRSGAKSSGGKYKSGSSAAA
KKTKTKASAKKSSASKAKSAKRKASKK

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014623, Length=398, Percent_Identity=32.4120603015075, Blast_Score=180, Evalue=6e-45,
Organism=Homo sapiens, GI190014625, Length=398, Percent_Identity=32.4120603015075, Blast_Score=179, Evalue=9e-45,
Organism=Homo sapiens, GI134288890, Length=415, Percent_Identity=28.433734939759, Blast_Score=149, Evalue=1e-35,
Organism=Homo sapiens, GI19115966, Length=561, Percent_Identity=23.8859180035651, Blast_Score=147, Evalue=6e-35,
Organism=Homo sapiens, GI219521928, Length=561, Percent_Identity=23.8859180035651, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI156105695, Length=308, Percent_Identity=26.2987012987013, Blast_Score=71, Evalue=5e-12,
Organism=Homo sapiens, GI156105693, Length=308, Percent_Identity=26.2987012987013, Blast_Score=71, Evalue=6e-12,
Organism=Escherichia coli, GI87082383, Length=726, Percent_Identity=60.3305785123967, Blast_Score=938, Evalue=0.0,
Organism=Escherichia coli, GI1787542, Length=652, Percent_Identity=29.2944785276074, Blast_Score=193, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI212645896, Length=401, Percent_Identity=29.925187032419, Blast_Score=164, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17553506, Length=536, Percent_Identity=27.9850746268657, Blast_Score=163, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6324552, Length=434, Percent_Identity=28.110599078341, Blast_Score=149, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6320499, Length=529, Percent_Identity=22.117202268431, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24649634, Length=441, Percent_Identity=29.9319727891156, Blast_Score=174, Evalue=3e-43,
Organism=Drosophila melanogaster, GI19922976, Length=364, Percent_Identity=27.1978021978022, Blast_Score=136, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24654597, Length=364, Percent_Identity=27.1978021978022, Blast_Score=136, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24654592, Length=364, Percent_Identity=27.1978021978022, Blast_Score=135, Evalue=9e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 93458; Mature: 93458

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II ; PS00177 TOPOISOMERASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQDPHIKREQEKYENPIPSREYILDYLRSQKSPLTREHIATALKIEGEEQLEAIRRRLR
CCCCCCCCCHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHEECCHHHHHHHHHHHH
AMERDGELVFTRGQSYGLPERMDLLTGTVIGHRDGFGFLKLEEGGDDLYINNRDMLMYFH
HHCCCCCEEEECCCCCCCCHHHHHHHHHEEECCCCCEEEEEECCCCEEEECCCCEEEEEE
GDRVLAQKAGVDRKGRREARIVRLVEERNAALVGRFHLDAGMGFVIADDRRITQEILVPE
CCCHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCEEEEECCCHHHHHHCCCC
EDRKGARQGDIVVLELTRRPGRYVKAAGKVTEVLGKEMAPGMEIEIALRNYDLPHTWSGL
HHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHH
IEKKLRKIPDEVTEADKEGRVDLRQLPLVTIDGEDARDFDDAVYAEKKKSGGWRLWVAIA
HHHHHHHCCHHHHCCCCCCCCCHHHCCEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEEE
DVSHYVRTESALDKEARARGNSVYFPSQVIPMLPEKISNGLCSLMPKVDRLCMVAEMTIS
HHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHH
AAGKLSGYKFYPAVMHSHARLTYTQVADMLEGGEVSDELKPIFPHLQTLQSLYLTLDETR
HHCCCCCCEECHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AERGAIAFETTETQFIFNEQRKIDKIVPRSRNQAHKIIEECMILANVASAKFVKKHKGEV
HHCCCEEEECCCCEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
LYRVHESPSEQKLTNFKDFLKERGLTMEGGLEPEPKDYQAVMEQVADRPDAELIQVMLLR
EEEECCCCCHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
SMRQATYTPDNEGHFGLALEEYSHFTSPIRRYPDLILHRVIRYLLAKQENTALTDQWTAD
HHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GGYHYKIEELDQLGEECSTTERRADEATRDVNDWLKCEFMQDHVGDTFEAVIASVTHFGM
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
FVRLNDLFIDGLVHISSLGSDYYQYDNMRQRLVGEASGQVYQIGDTVTVKVAGVNLDDRQ
HEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEECCEEEEEEEECCCCCCE
IDLMMEGDSAGGKRRRPTKPLTARERVNREGAKLGAKRESSRGKGAEGDSESKSETKRKP
EEEEEECCCCCCCCCCCCCCCHHHHHHCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCC
SRSGAKSSGGKYKSGSSAAAKKTKTKASAKKSSASKAKSAKRKASKK
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIQDPHIKREQEKYENPIPSREYILDYLRSQKSPLTREHIATALKIEGEEQLEAIRRRLR
CCCCCCCCCHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHEECCHHHHHHHHHHHH
AMERDGELVFTRGQSYGLPERMDLLTGTVIGHRDGFGFLKLEEGGDDLYINNRDMLMYFH
HHCCCCCEEEECCCCCCCCHHHHHHHHHEEECCCCCEEEEEECCCCEEEECCCCEEEEEE
GDRVLAQKAGVDRKGRREARIVRLVEERNAALVGRFHLDAGMGFVIADDRRITQEILVPE
CCCHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCEEEEECCCHHHHHHCCCC
EDRKGARQGDIVVLELTRRPGRYVKAAGKVTEVLGKEMAPGMEIEIALRNYDLPHTWSGL
HHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHH
IEKKLRKIPDEVTEADKEGRVDLRQLPLVTIDGEDARDFDDAVYAEKKKSGGWRLWVAIA
HHHHHHHCCHHHHCCCCCCCCCHHHCCEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEEE
DVSHYVRTESALDKEARARGNSVYFPSQVIPMLPEKISNGLCSLMPKVDRLCMVAEMTIS
HHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHH
AAGKLSGYKFYPAVMHSHARLTYTQVADMLEGGEVSDELKPIFPHLQTLQSLYLTLDETR
HHCCCCCCEECHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AERGAIAFETTETQFIFNEQRKIDKIVPRSRNQAHKIIEECMILANVASAKFVKKHKGEV
HHCCCEEEECCCCEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
LYRVHESPSEQKLTNFKDFLKERGLTMEGGLEPEPKDYQAVMEQVADRPDAELIQVMLLR
EEEECCCCCHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
SMRQATYTPDNEGHFGLALEEYSHFTSPIRRYPDLILHRVIRYLLAKQENTALTDQWTAD
HHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GGYHYKIEELDQLGEECSTTERRADEATRDVNDWLKCEFMQDHVGDTFEAVIASVTHFGM
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
FVRLNDLFIDGLVHISSLGSDYYQYDNMRQRLVGEASGQVYQIGDTVTVKVAGVNLDDRQ
HEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEECCEEEEEEEECCCCCCE
IDLMMEGDSAGGKRRRPTKPLTARERVNREGAKLGAKRESSRGKGAEGDSESKSETKRKP
EEEEEECCCCCCCCCCCCCCCHHHHHHCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCC
SRSGAKSSGGKYKSGSSAAAKKTKTKASAKKSSASKAKSAKRKASKK
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]