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The map label for this gene is btuB [H]

Identifier: 167625531

GI number: 167625531

Start: 4421071

End: 4423107

Strand: Reverse

Name: btuB [H]

Synonym: Shal_3625

Alternate gene names: 167625531

Gene position: 4423107-4421071 (Counterclockwise)

Preceding gene: 167625532

Following gene: 167625530

Centisome position: 84.62

GC content: 43.2

Gene sequence:

>2037_bases
GTGATCAAAACAAGAAATACTAAAATCGCAGTCATCATCAGTAGTTTGTTGGCATGCCAATACGCAGTGGCCAGTGATAC
AAATGACGTGTTCTCTCTCGGTGAGATTGTTGTTTCAGAGGAAACAGGCGTTAGAGATATCGCAATCAATAACACCATGA
CCGCAGAGCAAATTGAGCTGATAGGCGCAAAAACGGTCGCCGATGCACTCGACTATATACCTGGCGTACATGTAGCTCAA
TCAAGTAAGGGCGAGAAGTTTCTGACTATTCAGGGTTTTGAGCAAGATAAGGTGCTTATTTTGCTTGATGGTGTGCCTTA
CTATGAAACTAACTATGGTCAGTTAGACCTTAACCAAATACCTGCCAACATCATTGCAAAAATTGATGTGGTTAAAGGTG
CGTCATCAGTGCTTTATGGTCCAAATGGTATGGGCGGTGTAGTCAACATCATCACCAAGAAAGGCCAAGAGGGGGTTAGT
GGTGATCTACAAGCGTCTTTTGGTCAGATGGGTCAAAATTACCAGTCGGGTACACTTAGCTTAGGTAAGAACGGCTTTAG
TCTATTTGCATCTGTCGATCACCGTGGCCGTGATGCGATGCGGATGTCTAATGACTTCGAACCAGTACTGTCCGATGTGA
GAGACAAGTATGGCGACTTACCAAAGCAGATGATCGTTGAAGATGGTGGTAAACGTGAAAACTCGGCTTACGAGTCGACT
AATATCTGGGTTCGTGGTGGTTACGCTAACGAAAATACCGAACTATTTGCCAGTGTATTTAGCTTAGACTCAGATCGTGA
ATTGCCCTATAACACCCGTAACAACAAGGTATTTAGTGACTTTAGTAGCTTTGCCGATATCTCCGAATATAAAGATACGG
GGATGGATTTAAGTGGTTTACACCGCGTTAATGATTGGCTCACTGTTCGTGCATTAGGCTACTACCATATGCATAACGAT
AGTTATGACTCCTATAGCAATCCAGAAAAAGACGTCAAATTAGCGACCAGTAGCTTCAGTGACTACACAGCAGGTGGCGC
CTTGTTTACCGATATGGTGTTAGCCGATTGGAACAGTTTAAGCCTGTCTGTAAACTTCAAGAATGATGTTCATAAGAAGA
AAAATGTCGCATATATAGACACTGACCGTTCCCATGCTTATGAGCGCTCTCAACTCGATACCATTAGTTTGGCTGCTGAA
GATACCATGACATTTGGTGCGCTAAATGTGGTTGCAGGTATCGCATGGCATAAACAAACGGTTGTTGAAGATCGTGACTA
CGATGCTGCATCGGGTGAGGATGGTTCAGATACTTTAGATCCTATGTTAGGTATGAGCTACACCTTAGATAATGCAGGTT
TAATCTACGGTTCTATTGCGCAAAAAACTCGTTTCGCAACCTTTACCGAAATGTATGACGATACGGGAGCACGTCACGAC
ATTAAACCGGAGCGTAATACGAGCTATACCTTAGGTTGGAAGAACGATTTTAGCCATCAGTTATTAAACAGTATCGATAT
CGGTCTGTTTTACCATGATGTCAGCGATAAGATTGTCTCTACCTATATGCCTGATCCAACTGATCCAGATTGGGATCTAG
AAGTTTATCAAAACGTGGGAAGCTCAGAGTTTTACGGCATCGAGATTAGTACCCAAAGTCAGCTGAGTGAAAATATCAGT
TTATCTCTAGATTACACTTACACGCATGCTCGCAATACCACTGATGATCGTGATTCTGACTACTTCCGTGATATTCCAAA
GGACACCGTGACTGCGATTGTTAACTGGTATCAACCTTGGCTAGATATCGACAGTAATCTGCGCGTTCGTTACCGCACAG
ATATTCTGATTGATGATCGCTCTGATGAGTGGGAGTCTGAGACCTTAACGATTGATATGGGGATTAATAAGTCGATTACA
CCGCAGCTCTCTGCTTACGTTAATCTTAATAACCTACTCGATGAGTCACACTACGAAGGATACGGTCAGCCAAATGAAGG
CCGCTCTTATGAAGTTGGCGTAAAGTACCGCTTCTAA

Upstream 100 bases:

>100_bases
GTAAGATTAAGAATAAGATATGCGCGAATTTTCGGTGAAGCAGGTTCTTTATTGGTGTTAAAGGCTTGTGATCCCTACAA
CGAGCAGTTCGGAGTCTTCG

Downstream 100 bases:

>100_bases
GGATTAGGAATGTTTAACAGACTATTTAGTGCTGTTGTCATTCTCCTTAGTGGTCTTTCAAGTGTATCGGCAGCGCCGAT
ACACTTGGTCGATCAGCAAG

Product: TonB-dependent receptor plug

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 678; Mature: 678

Protein sequence:

>678_residues
MIKTRNTKIAVIISSLLACQYAVASDTNDVFSLGEIVVSEETGVRDIAINNTMTAEQIELIGAKTVADALDYIPGVHVAQ
SSKGEKFLTIQGFEQDKVLILLDGVPYYETNYGQLDLNQIPANIIAKIDVVKGASSVLYGPNGMGGVVNIITKKGQEGVS
GDLQASFGQMGQNYQSGTLSLGKNGFSLFASVDHRGRDAMRMSNDFEPVLSDVRDKYGDLPKQMIVEDGGKRENSAYEST
NIWVRGGYANENTELFASVFSLDSDRELPYNTRNNKVFSDFSSFADISEYKDTGMDLSGLHRVNDWLTVRALGYYHMHND
SYDSYSNPEKDVKLATSSFSDYTAGGALFTDMVLADWNSLSLSVNFKNDVHKKKNVAYIDTDRSHAYERSQLDTISLAAE
DTMTFGALNVVAGIAWHKQTVVEDRDYDAASGEDGSDTLDPMLGMSYTLDNAGLIYGSIAQKTRFATFTEMYDDTGARHD
IKPERNTSYTLGWKNDFSHQLLNSIDIGLFYHDVSDKIVSTYMPDPTDPDWDLEVYQNVGSSEFYGIEISTQSQLSENIS
LSLDYTYTHARNTTDDRDSDYFRDIPKDTVTAIVNWYQPWLDIDSNLRVRYRTDILIDDRSDEWESETLTIDMGINKSIT
PQLSAYVNLNNLLDESHYEGYGQPNEGRSYEVGVKYRF

Sequences:

>Translated_678_residues
MIKTRNTKIAVIISSLLACQYAVASDTNDVFSLGEIVVSEETGVRDIAINNTMTAEQIELIGAKTVADALDYIPGVHVAQ
SSKGEKFLTIQGFEQDKVLILLDGVPYYETNYGQLDLNQIPANIIAKIDVVKGASSVLYGPNGMGGVVNIITKKGQEGVS
GDLQASFGQMGQNYQSGTLSLGKNGFSLFASVDHRGRDAMRMSNDFEPVLSDVRDKYGDLPKQMIVEDGGKRENSAYEST
NIWVRGGYANENTELFASVFSLDSDRELPYNTRNNKVFSDFSSFADISEYKDTGMDLSGLHRVNDWLTVRALGYYHMHND
SYDSYSNPEKDVKLATSSFSDYTAGGALFTDMVLADWNSLSLSVNFKNDVHKKKNVAYIDTDRSHAYERSQLDTISLAAE
DTMTFGALNVVAGIAWHKQTVVEDRDYDAASGEDGSDTLDPMLGMSYTLDNAGLIYGSIAQKTRFATFTEMYDDTGARHD
IKPERNTSYTLGWKNDFSHQLLNSIDIGLFYHDVSDKIVSTYMPDPTDPDWDLEVYQNVGSSEFYGIEISTQSQLSENIS
LSLDYTYTHARNTTDDRDSDYFRDIPKDTVTAIVNWYQPWLDIDSNLRVRYRTDILIDDRSDEWESETLTIDMGINKSIT
PQLSAYVNLNNLLDESHYEGYGQPNEGRSYEVGVKYRF
>Mature_678_residues
MIKTRNTKIAVIISSLLACQYAVASDTNDVFSLGEIVVSEETGVRDIAINNTMTAEQIELIGAKTVADALDYIPGVHVAQ
SSKGEKFLTIQGFEQDKVLILLDGVPYYETNYGQLDLNQIPANIIAKIDVVKGASSVLYGPNGMGGVVNIITKKGQEGVS
GDLQASFGQMGQNYQSGTLSLGKNGFSLFASVDHRGRDAMRMSNDFEPVLSDVRDKYGDLPKQMIVEDGGKRENSAYEST
NIWVRGGYANENTELFASVFSLDSDRELPYNTRNNKVFSDFSSFADISEYKDTGMDLSGLHRVNDWLTVRALGYYHMHND
SYDSYSNPEKDVKLATSSFSDYTAGGALFTDMVLADWNSLSLSVNFKNDVHKKKNVAYIDTDRSHAYERSQLDTISLAAE
DTMTFGALNVVAGIAWHKQTVVEDRDYDAASGEDGSDTLDPMLGMSYTLDNAGLIYGSIAQKTRFATFTEMYDDTGARHD
IKPERNTSYTLGWKNDFSHQLLNSIDIGLFYHDVSDKIVSTYMPDPTDPDWDLEVYQNVGSSEFYGIEISTQSQLSENIS
LSLDYTYTHARNTTDDRDSDYFRDIPKDTVTAIVNWYQPWLDIDSNLRVRYRTDILIDDRSDEWESETLTIDMGINKSIT
PQLSAYVNLNNLLDESHYEGYGQPNEGRSYEVGVKYRF

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=206, Percent_Identity=28.6407766990291, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1790405, Length=182, Percent_Identity=28.021978021978, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 75792; Mature: 75792

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKTRNTKIAVIISSLLACQYAVASDTNDVFSLGEIVVSEETGVRDIAINNTMTAEQIEL
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEECCCCCEEEEECCCCCHHHHHH
IGAKTVADALDYIPGVHVAQSSKGEKFLTIQGFEQDKVLILLDGVPYYETNYGQLDLNQI
HHHHHHHHHHHHCCCCEEECCCCCCEEEEEECCCCCCEEEEECCCCCEECCCCEEEHHHC
PANIIAKIDVVKGASSVLYGPNGMGGVVNIITKKGQEGVSGDLQASFGQMGQNYQSGTLS
CCCCEEEEEEECCCCCEEECCCCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCCCCCCEE
LGKNGFSLFASVDHRGRDAMRMSNDFEPVLSDVRDKYGDLPKQMIVEDGGKRENSAYEST
ECCCCEEEEEECCCCCCHHHHHCCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCC
NIWVRGGYANENTELFASVFSLDSDRELPYNTRNNKVFSDFSSFADISEYKDTGMDLSGL
EEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHH
HRVNDWLTVRALGYYHMHNDSYDSYSNPEKDVKLATSSFSDYTAGGALFTDMVLADWNSL
HHHCCEEEEEEEEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCEE
SLSVNFKNDVHKKKNVAYIDTDRSHAYERSQLDTISLAAEDTMTFGALNVVAGIAWHKQT
EEEEECCCCCCCCCCEEEEECCCHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
VVEDRDYDAASGEDGSDTLDPMLGMSYTLDNAGLIYGSIAQKTRFATFTEMYDDTGARHD
HCCCCCCCCCCCCCCCCCHHHHHCCEEEECCCCEEEECHHHHHHHHHHHHHHHCCCCCCC
IKPERNTSYTLGWKNDFSHQLLNSIDIGLFYHDVSDKIVSTYMPDPTDPDWDLEVYQNVG
CCCCCCCEEEEECCCCHHHHHHHHCCEEEEEECHHHHHHHHCCCCCCCCCCCHHHHHCCC
SSEFYGIEISTQSQLSENISLSLDYTYTHARNTTDDRDSDYFRDIPKDTVTAIVNWYQPW
CCEEEEEEECCHHHHCCCCEEEEEEEEEECCCCCCCCCCHHHHHCCHHHHHHHHHHHHHH
LDIDSNLRVRYRTDILIDDRSDEWESETLTIDMGINKSITPQLSAYVNLNNLLDESHYEG
CCCCCCCEEEEEEEEEEECCCCCCCCCEEEEEECCCCCCCCCEEEEEEHHHHHCCCCCCC
YGQPNEGRSYEVGVKYRF
CCCCCCCCCEEEEEEEEC
>Mature Secondary Structure
MIKTRNTKIAVIISSLLACQYAVASDTNDVFSLGEIVVSEETGVRDIAINNTMTAEQIEL
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEECCCCCEEEEECCCCCHHHHHH
IGAKTVADALDYIPGVHVAQSSKGEKFLTIQGFEQDKVLILLDGVPYYETNYGQLDLNQI
HHHHHHHHHHHHCCCCEEECCCCCCEEEEEECCCCCCEEEEECCCCCEECCCCEEEHHHC
PANIIAKIDVVKGASSVLYGPNGMGGVVNIITKKGQEGVSGDLQASFGQMGQNYQSGTLS
CCCCEEEEEEECCCCCEEECCCCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCCCCCCEE
LGKNGFSLFASVDHRGRDAMRMSNDFEPVLSDVRDKYGDLPKQMIVEDGGKRENSAYEST
ECCCCEEEEEECCCCCCHHHHHCCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCC
NIWVRGGYANENTELFASVFSLDSDRELPYNTRNNKVFSDFSSFADISEYKDTGMDLSGL
EEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHH
HRVNDWLTVRALGYYHMHNDSYDSYSNPEKDVKLATSSFSDYTAGGALFTDMVLADWNSL
HHHCCEEEEEEEEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCEE
SLSVNFKNDVHKKKNVAYIDTDRSHAYERSQLDTISLAAEDTMTFGALNVVAGIAWHKQT
EEEEECCCCCCCCCCEEEEECCCHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
VVEDRDYDAASGEDGSDTLDPMLGMSYTLDNAGLIYGSIAQKTRFATFTEMYDDTGARHD
HCCCCCCCCCCCCCCCCCHHHHHCCEEEECCCCEEEECHHHHHHHHHHHHHHHCCCCCCC
IKPERNTSYTLGWKNDFSHQLLNSIDIGLFYHDVSDKIVSTYMPDPTDPDWDLEVYQNVG
CCCCCCCEEEEECCCCHHHHHHHHCCEEEEEECHHHHHHHHCCCCCCCCCCCHHHHHCCC
SSEFYGIEISTQSQLSENISLSLDYTYTHARNTTDDRDSDYFRDIPKDTVTAIVNWYQPW
CCEEEEEEECCHHHHCCCCEEEEEEEEEECCCCCCCCCCHHHHHCCHHHHHHHHHHHHHH
LDIDSNLRVRYRTDILIDDRSDEWESETLTIDMGINKSITPQLSAYVNLNNLLDESHYEG
CCCCCCCEEEEEEEEEEECCCCCCCCCEEEEEECCCCCCCCCEEEEEEHHHHHCCCCCCC
YGQPNEGRSYEVGVKYRF
CCCCCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA