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The map label for this gene is pabA [H]

Identifier: 167625519

GI number: 167625519

Start: 4410457

End: 4411029

Strand: Reverse

Name: pabA [H]

Synonym: Shal_3613

Alternate gene names: 167625519

Gene position: 4411029-4410457 (Counterclockwise)

Preceding gene: 167625520

Following gene: 167625518

Centisome position: 84.39

GC content: 45.55

Gene sequence:

>573_bases
ATGATCTTAATGATCGACAATTACGACTCATTTACTTTTAATCTGGTGCAGTATTTTCAGCAGCTTGGGCAAGAGATTGT
GGTTAAGCGCAACGACGAAATCAGTCTCCAAGATATTGAGGCTTTAGCACCGAGTCACTTAGTGATCTCACCTGGCCCTT
GTACGCCAAACGAGGCGGGTCTGTCGTTATCAATTATTGAACACTTTGTTGGCCAACTGCCAATCCTTGGGGTTTGTTTA
GGGCATCAGGCGATTGCACAGGTATTTGGTGCGAATGTTATTCGTGCTAAGCGAGTTATGCATGGTAAAACCAGTGCCAT
AGCGCATACCGACAGTGGTTTATTTCGTGGTTTGAATAACCCGCTAACCGTCACCCGTTATCACTCTTTGCTGGTCGATA
GTGTACCCGAGGGCTTTGCTTTAGATGCTTGGTTTGACGATCCTGTTTATGGGCGAGAGATCATGGCGATGAGTATGCCT
GCTAAGAAGATCTATGGTGTGCAGTTTCATCCGGAGTCTATTCTGACCGAACAAGGCCATGAGCTGTTAGCAAACTTTAT
CCAAATCACCTAA

Upstream 100 bases:

>100_bases
ATTCGTACAGCTAGAGGACAAACTCTGATGATCCAAGGTGATGGCTGTGGTAGCATCAGCGCCCAAATCACCCACATTGA
TATAGGTTCTTGGATCTTTT

Downstream 100 bases:

>100_bases
ATCGGCATTATTCGGGTATATCTGGGAAGAACCTAGTATGACGTGCAGTTTCATACTTAAGCCGAGCATCTATCCTGACC
GAGCAAGGCCATGAGCTGTT

Product: glutamine amidotransferase of anthranilate synthase

Products: NA

Alternate protein names: ADC synthase [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MILMIDNYDSFTFNLVQYFQQLGQEIVVKRNDEISLQDIEALAPSHLVISPGPCTPNEAGLSLSIIEHFVGQLPILGVCL
GHQAIAQVFGANVIRAKRVMHGKTSAIAHTDSGLFRGLNNPLTVTRYHSLLVDSVPEGFALDAWFDDPVYGREIMAMSMP
AKKIYGVQFHPESILTEQGHELLANFIQIT

Sequences:

>Translated_190_residues
MILMIDNYDSFTFNLVQYFQQLGQEIVVKRNDEISLQDIEALAPSHLVISPGPCTPNEAGLSLSIIEHFVGQLPILGVCL
GHQAIAQVFGANVIRAKRVMHGKTSAIAHTDSGLFRGLNNPLTVTRYHSLLVDSVPEGFALDAWFDDPVYGREIMAMSMP
AKKIYGVQFHPESILTEQGHELLANFIQIT
>Mature_190_residues
MILMIDNYDSFTFNLVQYFQQLGQEIVVKRNDEISLQDIEALAPSHLVISPGPCTPNEAGLSLSIIEHFVGQLPILGVCL
GHQAIAQVFGANVIRAKRVMHGKTSAIAHTDSGLFRGLNNPLTVTRYHSLLVDSVPEGFALDAWFDDPVYGREIMAMSMP
AKKIYGVQFHPESILTEQGHELLANFIQIT

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI4504035, Length=114, Percent_Identity=36.8421052631579, Blast_Score=70, Evalue=8e-13,
Organism=Escherichia coli, GI1789760, Length=190, Percent_Identity=63.1578947368421, Blast_Score=253, Evalue=7e-69,
Organism=Escherichia coli, GI1787517, Length=185, Percent_Identity=44.3243243243243, Blast_Score=157, Evalue=5e-40,
Organism=Escherichia coli, GI1788854, Length=195, Percent_Identity=27.6923076923077, Blast_Score=67, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI133901714, Length=141, Percent_Identity=31.9148936170213, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71992710, Length=141, Percent_Identity=31.9148936170213, Blast_Score=63, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71992717, Length=141, Percent_Identity=31.9148936170213, Blast_Score=63, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322638, Length=192, Percent_Identity=41.1458333333333, Blast_Score=162, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6324361, Length=211, Percent_Identity=30.8056872037915, Blast_Score=82, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6323873, Length=116, Percent_Identity=35.3448275862069, Blast_Score=65, Evalue=5e-12,
Organism=Drosophila melanogaster, GI281365319, Length=119, Percent_Identity=32.7731092436975, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 21003; Mature: 21003

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILMIDNYDSFTFNLVQYFQQLGQEIVVKRNDEISLQDIEALAPSHLVISPGPCTPNEAG
CEEEEECCCCHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHCCCCCEEEECCCCCCCCCC
LSLSIIEHFVGQLPILGVCLGHQAIAQVFGANVIRAKRVMHGKTSAIAHTDSGLFRGLNN
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHEEECCCHHHHCCCC
PLTVTRYHSLLVDSVPEGFALDAWFDDPVYGREIMAMSMPAKKIYGVQFHPESILTEQGH
CEEHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCEEECCCHHHHEEEEECCHHHHHHHHH
ELLANFIQIT
HHHHHHHHCC
>Mature Secondary Structure
MILMIDNYDSFTFNLVQYFQQLGQEIVVKRNDEISLQDIEALAPSHLVISPGPCTPNEAG
CEEEEECCCCHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHCCCCCEEEECCCCCCCCCC
LSLSIIEHFVGQLPILGVCLGHQAIAQVFGANVIRAKRVMHGKTSAIAHTDSGLFRGLNN
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHEEECCCHHHHCCCC
PLTVTRYHSLLVDSVPEGFALDAWFDDPVYGREIMAMSMPAKKIYGVQFHPESILTEQGH
CEEHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCEEECCCHHHHEEEEECCHHHHHHHHH
ELLANFIQIT
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3894673 [H]