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The map label for this gene is ndh [H]

Identifier: 167625408

GI number: 167625408

Start: 4270445

End: 4271746

Strand: Reverse

Name: ndh [H]

Synonym: Shal_3500

Alternate gene names: 167625408

Gene position: 4271746-4270445 (Counterclockwise)

Preceding gene: 167625410

Following gene: 167625405

Centisome position: 81.73

GC content: 45.78

Gene sequence:

>1302_bases
ATGAGATCGGCAAATCCAAAAATTGTGATTGTAGGCGGTGGCGCTGGTGGTTTGGAGCTAGCGACTCAATTGGGTCATAA
GCTAGGCAAGAAAAACCTAGCGCAAATCATCTTAGTCGATAAGAACCGAACTCACATTTGGAAACCATTACTCCACGAGG
TGGCTACAGGATCTTTGGATAGTGCGCTTGATGGCGTGGTTTATTCTGCCCACGCGGCCAAGCATGGTTATCAATTTCAA
TTGGGGACTTTTTGTGACTTAGATGAAGCGAATCAGGCGATTTCAGTCGCACCTATTTTAGATGAAGCGGGTAAAGTGCT
ATTACCTGAGCGGCAGATCCAATACGACAAACTGGTTATCGCTATTGGTAGCATCAGCAATGACTTTAATACCCCTGGTG
TTACAGAAAACTGCTTCTTTTTAGATTCTCACCAGCAAGCTAACCGCTTTCATCACGCTCTGTTAGATAGCTTTACCCGA
GTGCATCAGTCGGAAACCCTTAACGAACTTAACATTGCCATTGTCGGTGGTGGTGCAACAGGCGTTGAGTTATCTGCTGA
ACTGTACCATGTTACCGATCTGCTCAAGGTTTACGGTTTGAGTAAGATGACCGCCGACAAACTCAATATTCACTTGATTG
AAGCCGGTGAGCGTATACTGCCTGCCTTGCCTGAACGCATTGCCACTTCTGCAAGACGCGAACTAAGTAAGCTAGGCGTA
AACGTGATGGAAAATACCCGCATTAGTGAAGCGACATCTGCAGGCTTTGTTACCTCAGAAGGTGAGTTAATCGAAGCCAA
TATTATGCTGTGGGCTGCGGGCGTTAAAGCGCCAGACTTTATTAAAGATATCGGTCTGTTTGAGCTTAACCGTGTTAATC
AAATTATGGTTAAACCGAGCCTATTAAGCACCGTTAGTGATGATATTTATGTGATAGGCGATTGCTGTGCATGCCAACAA
GCCGATGGCAGCTTTGTACCGCCAAGAGCACAATCTGCTCATCAGATGGCGCAGTGTGTTGAGACAAATATTCTTAACGA
GCTTAAAGGTGAGCCGCTTGTAGATTACGTCTATGTAGATCATGGCTCATTGGTTAACCTATCGCGCTACAGTACGGTCG
GTAGCTTGATGGGCAACCTGACTAAGAACAGTATGTTTGTCGAAGGTAAGATTGCTCGCCTAGTGTATATCTCACTCTAC
CGTATGCACCAACAAGCGATTCATGGCACGTTAAAGACCATAGCGTTATGGTGCGCTGAAAAGCTAATGCGCGTAGTGCG
CCCAAGAATGAAGCTGCACTAA

Upstream 100 bases:

>100_bases
AACATAGCAGCCGCTAAGTAAGTGCACGTTAATTTAGCATCTTGTTCTATTGAAGCCTAAATGGGGTTTCAATATTTGAC
CTTTATAGAGGAATGAAGTG

Downstream 100 bases:

>100_bases
TATTTAGGGCTGGGCTAGCATTTAGAAGGGCTATTAGCATTTCGTAGCGGTAGGAAAGTTTACAAGCTGTGCAGAAATTA
AGTTAATTCAAATAATAAAA

Product: NADH dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MRSANPKIVIVGGGAGGLELATQLGHKLGKKNLAQIILVDKNRTHIWKPLLHEVATGSLDSALDGVVYSAHAAKHGYQFQ
LGTFCDLDEANQAISVAPILDEAGKVLLPERQIQYDKLVIAIGSISNDFNTPGVTENCFFLDSHQQANRFHHALLDSFTR
VHQSETLNELNIAIVGGGATGVELSAELYHVTDLLKVYGLSKMTADKLNIHLIEAGERILPALPERIATSARRELSKLGV
NVMENTRISEATSAGFVTSEGELIEANIMLWAAGVKAPDFIKDIGLFELNRVNQIMVKPSLLSTVSDDIYVIGDCCACQQ
ADGSFVPPRAQSAHQMAQCVETNILNELKGEPLVDYVYVDHGSLVNLSRYSTVGSLMGNLTKNSMFVEGKIARLVYISLY
RMHQQAIHGTLKTIALWCAEKLMRVVRPRMKLH

Sequences:

>Translated_433_residues
MRSANPKIVIVGGGAGGLELATQLGHKLGKKNLAQIILVDKNRTHIWKPLLHEVATGSLDSALDGVVYSAHAAKHGYQFQ
LGTFCDLDEANQAISVAPILDEAGKVLLPERQIQYDKLVIAIGSISNDFNTPGVTENCFFLDSHQQANRFHHALLDSFTR
VHQSETLNELNIAIVGGGATGVELSAELYHVTDLLKVYGLSKMTADKLNIHLIEAGERILPALPERIATSARRELSKLGV
NVMENTRISEATSAGFVTSEGELIEANIMLWAAGVKAPDFIKDIGLFELNRVNQIMVKPSLLSTVSDDIYVIGDCCACQQ
ADGSFVPPRAQSAHQMAQCVETNILNELKGEPLVDYVYVDHGSLVNLSRYSTVGSLMGNLTKNSMFVEGKIARLVYISLY
RMHQQAIHGTLKTIALWCAEKLMRVVRPRMKLH
>Mature_433_residues
MRSANPKIVIVGGGAGGLELATQLGHKLGKKNLAQIILVDKNRTHIWKPLLHEVATGSLDSALDGVVYSAHAAKHGYQFQ
LGTFCDLDEANQAISVAPILDEAGKVLLPERQIQYDKLVIAIGSISNDFNTPGVTENCFFLDSHQQANRFHHALLDSFTR
VHQSETLNELNIAIVGGGATGVELSAELYHVTDLLKVYGLSKMTADKLNIHLIEAGERILPALPERIATSARRELSKLGV
NVMENTRISEATSAGFVTSEGELIEANIMLWAAGVKAPDFIKDIGLFELNRVNQIMVKPSLLSTVSDDIYVIGDCCACQQ
ADGSFVPPRAQSAHQMAQCVETNILNELKGEPLVDYVYVDHGSLVNLSRYSTVGSLMGNLTKNSMFVEGKIARLVYISLY
RMHQQAIHGTLKTIALWCAEKLMRVVRPRMKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=434, Percent_Identity=58.9861751152074, Blast_Score=527, Evalue=1e-151,
Organism=Saccharomyces cerevisiae, GI6323515, Length=372, Percent_Identity=24.4623655913978, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320118, Length=369, Percent_Identity=26.5582655826558, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323794, Length=356, Percent_Identity=25.8426966292135, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 47376; Mature: 47376

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSANPKIVIVGGGAGGLELATQLGHKLGKKNLAQIILVDKNRTHIWKPLLHEVATGSLD
CCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCHH
SALDGVVYSAHAAKHGYQFQLGTFCDLDEANQAISVAPILDEAGKVLLPERQIQYDKLVI
HHHHHHHEEHHHHCCCCEEEECCCCCCCCCCCEEEEEEEHHCCCCEECCCHHCCCCEEEE
AIGSISNDFNTPGVTENCFFLDSHQQANRFHHALLDSFTRVHQSETLNELNIAIVGGGAT
EEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
GVELSAELYHVTDLLKVYGLSKMTADKLNIHLIEAGERILPALPERIATSARRELSKLGV
CCEEHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCC
NVMENTRISEATSAGFVTSEGELIEANIMLWAAGVKAPDFIKDIGLFELNRVNQIMVKPS
HHHCCCCCCHHCCCCEEECCCCEEEEEEEEEECCCCCCHHHHHCCCHHHCCCCCEEECCH
LLSTVSDDIYVIGDCCACQQADGSFVPPRAQSAHQMAQCVETNILNELKGEPLVDYVYVD
HHHHCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
HGSLVNLSRYSTVGSLMGNLTKNSMFVEGKIARLVYISLYRMHQQAIHGTLKTIALWCAE
CCCEEEHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLMRVVRPRMKLH
HHHHHHHHHHCCC
>Mature Secondary Structure
MRSANPKIVIVGGGAGGLELATQLGHKLGKKNLAQIILVDKNRTHIWKPLLHEVATGSLD
CCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCHH
SALDGVVYSAHAAKHGYQFQLGTFCDLDEANQAISVAPILDEAGKVLLPERQIQYDKLVI
HHHHHHHEEHHHHCCCCEEEECCCCCCCCCCCEEEEEEEHHCCCCEECCCHHCCCCEEEE
AIGSISNDFNTPGVTENCFFLDSHQQANRFHHALLDSFTRVHQSETLNELNIAIVGGGAT
EEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
GVELSAELYHVTDLLKVYGLSKMTADKLNIHLIEAGERILPALPERIATSARRELSKLGV
CCEEHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCC
NVMENTRISEATSAGFVTSEGELIEANIMLWAAGVKAPDFIKDIGLFELNRVNQIMVKPS
HHHCCCCCCHHCCCCEEECCCCEEEEEEEEEECCCCCCHHHHHCCCHHHCCCCCEEECCH
LLSTVSDDIYVIGDCCACQQADGSFVPPRAQSAHQMAQCVETNILNELKGEPLVDYVYVD
HHHHCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
HGSLVNLSRYSTVGSLMGNLTKNSMFVEGKIARLVYISLYRMHQQAIHGTLKTIALWCAE
CCCEEEHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLMRVVRPRMKLH
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]