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The map label for this gene is serB [H]

Identifier: 167625043

GI number: 167625043

Start: 3820991

End: 3821998

Strand: Reverse

Name: serB [H]

Synonym: Shal_3131

Alternate gene names: 167625043

Gene position: 3821998-3820991 (Counterclockwise)

Preceding gene: 167625045

Following gene: 167625042

Centisome position: 73.12

GC content: 47.42

Gene sequence:

>1008_bases
ATGGAAAGTTTGAGTCAATCGACTGTTTTTGCTTGGTTAAGTACCGAAGGTAGCATGTCTTTTACTGCTGGGGAACAAAG
TTATTTTCGTCATAACGAGGCGGAATATCCAAAAGGGTTTTCTCGTTATCGGATCTTGTTTTCCGAACTAGAAACCCTAA
ACGCCGCGCAACTGCAGGTTATTAATGACGCTGTAGACAGTTGGCTTGAGTCCCTAAATTGCAAGCTGAGCCTAGCTCTG
ATTAAACGTGATTGCGGCCTGAATTGCATTGAAGTCTGTACTCCAGAGCCTTTAAGCGCCGAACAGATTGCCGCTATTAG
TGAGACGGATTTTTTAGAGTTATTTGAGTTAACTTTCGACGCGCCGCAGCTAAGCCAAGTGGGTCTGTTGGTGATGGATA
TGGACTCAACCGCGATTGAAATCGAGTGTATCGATGAACTGGCCGAAATGGCAGGTGTAGGGCCTGCTGTAGCGGAAGTT
ACCGAGTTGGCAATGCAAGGTGAGCTTGATTTTGAGCAGAGCCTTAGGGCGCGGGTGGGCAAGCTTAAAGGCGCCGATGC
TGAAATTATCGATATTCTAAGAGCCAAGCTGCCTCTAATGCCGGGCCTTAAGGAGATGATCGCAGAGTTACAGAGTCATG
GCTGGCGTACCGTTGTGGCCTCAGGGGGCTTTACTCCTTTTGTGGATCAGCTTAAACAGCTATTGGCGCTAGATGCCGCT
TTTGCTAATAAGCTAGATATTGATAACGGTAAGCTATTGGGCACCGTTTCCGGGCAAGTGGTCGATGCTCAATATAAGGC
CGATACTGTGCTTAAGTGTGCTAAGCAGTGGCAGATAGCGGTGGGACAAAGAGTGGCGATAGGCGACGGTGCTAATGATA
TTCCGATGATCAATGCTGCTGACTTTGGTATTGCTTATCATGCCAAACCCAAGCTGGCTCAAGCGGCAGATGTCAGCATT
AATCGACTCAACCTTAAGGTTTTACCTTACCTGTTTCAGATGAGTTAG

Upstream 100 bases:

>100_bases
TTAGGCCTTTTAAATAGAACACTGAAACCCTTAATTTATTGTGTACTCACCTAATCATAATTGATTATGTCTGTACTCGG
TAGTTGGAGAGCTATAACTA

Downstream 100 bases:

>100_bases
CGCTTAACTTAAGTCGATGCCTGTTGTTGCTTTGCTAGGAAGACTCATAACGATTTTGTTGTGAGTTTTTCATGTTTGAA
AGAGGTTGCTATCGCCTTGT

Product: phosphoserine phosphatase SerB

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MESLSQSTVFAWLSTEGSMSFTAGEQSYFRHNEAEYPKGFSRYRILFSELETLNAAQLQVINDAVDSWLESLNCKLSLAL
IKRDCGLNCIEVCTPEPLSAEQIAAISETDFLELFELTFDAPQLSQVGLLVMDMDSTAIEIECIDELAEMAGVGPAVAEV
TELAMQGELDFEQSLRARVGKLKGADAEIIDILRAKLPLMPGLKEMIAELQSHGWRTVVASGGFTPFVDQLKQLLALDAA
FANKLDIDNGKLLGTVSGQVVDAQYKADTVLKCAKQWQIAVGQRVAIGDGANDIPMINAADFGIAYHAKPKLAQAADVSI
NRLNLKVLPYLFQMS

Sequences:

>Translated_335_residues
MESLSQSTVFAWLSTEGSMSFTAGEQSYFRHNEAEYPKGFSRYRILFSELETLNAAQLQVINDAVDSWLESLNCKLSLAL
IKRDCGLNCIEVCTPEPLSAEQIAAISETDFLELFELTFDAPQLSQVGLLVMDMDSTAIEIECIDELAEMAGVGPAVAEV
TELAMQGELDFEQSLRARVGKLKGADAEIIDILRAKLPLMPGLKEMIAELQSHGWRTVVASGGFTPFVDQLKQLLALDAA
FANKLDIDNGKLLGTVSGQVVDAQYKADTVLKCAKQWQIAVGQRVAIGDGANDIPMINAADFGIAYHAKPKLAQAADVSI
NRLNLKVLPYLFQMS
>Mature_335_residues
MESLSQSTVFAWLSTEGSMSFTAGEQSYFRHNEAEYPKGFSRYRILFSELETLNAAQLQVINDAVDSWLESLNCKLSLAL
IKRDCGLNCIEVCTPEPLSAEQIAAISETDFLELFELTFDAPQLSQVGLLVMDMDSTAIEIECIDELAEMAGVGPAVAEV
TELAMQGELDFEQSLRARVGKLKGADAEIIDILRAKLPLMPGLKEMIAELQSHGWRTVVASGGFTPFVDQLKQLLALDAA
FANKLDIDNGKLLGTVSGQVVDAQYKADTVLKCAKQWQIAVGQRVAIGDGANDIPMINAADFGIAYHAKPKLAQAADVSI
NRLNLKVLPYLFQMS

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=192, Percent_Identity=30.7291666666667, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1790849, Length=204, Percent_Identity=57.843137254902, Blast_Score=241, Evalue=4e-65,
Organism=Caenorhabditis elegans, GI115534456, Length=188, Percent_Identity=30.3191489361702, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534454, Length=188, Percent_Identity=30.3191489361702, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534458, Length=192, Percent_Identity=29.6875, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321647, Length=206, Percent_Identity=39.8058252427184, Blast_Score=142, Evalue=7e-35,
Organism=Drosophila melanogaster, GI24661601, Length=203, Percent_Identity=28.0788177339901, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 36529; Mature: 36529

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLSQSTVFAWLSTEGSMSFTAGEQSYFRHNEAEYPKGFSRYRILFSELETLNAAQLQV
CCCCCCCEEEEEEECCCCEEEECCCHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHH
INDAVDSWLESLNCKLSLALIKRDCGLNCIEVCTPEPLSAEQIAAISETDFLELFELTFD
HHHHHHHHHHHCCCEEEEEEEHHCCCCCEEECCCCCCCCHHHHHHCCCCHHHHHHHHHCC
APQLSQVGLLVMDMDSTAIEIECIDELAEMAGVGPAVAEVTELAMQGELDFEQSLRARVG
CCCHHHCCEEEEECCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
KLKGADAEIIDILRAKLPLMPGLKEMIAELQSHGWRTVVASGGFTPFVDQLKQLLALDAA
HCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHH
FANKLDIDNGKLLGTVSGQVVDAQYKADTVLKCAKQWQIAVGQRVAIGDGANDIPMINAA
HHCCEECCCCEEEEEECCEEEECHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEECC
DFGIAYHAKPKLAQAADVSINRLNLKVLPYLFQMS
CCCEEEECCCCCCHHHCCEEEEEEHEEEHHHHHCC
>Mature Secondary Structure
MESLSQSTVFAWLSTEGSMSFTAGEQSYFRHNEAEYPKGFSRYRILFSELETLNAAQLQV
CCCCCCCEEEEEEECCCCEEEECCCHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHH
INDAVDSWLESLNCKLSLALIKRDCGLNCIEVCTPEPLSAEQIAAISETDFLELFELTFD
HHHHHHHHHHHCCCEEEEEEEHHCCCCCEEECCCCCCCCHHHHHHCCCCHHHHHHHHHCC
APQLSQVGLLVMDMDSTAIEIECIDELAEMAGVGPAVAEVTELAMQGELDFEQSLRARVG
CCCHHHCCEEEEECCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
KLKGADAEIIDILRAKLPLMPGLKEMIAELQSHGWRTVVASGGFTPFVDQLKQLLALDAA
HCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHH
FANKLDIDNGKLLGTVSGQVVDAQYKADTVLKCAKQWQIAVGQRVAIGDGANDIPMINAA
HHCCEECCCCEEEEEECCEEEECHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEECC
DFGIAYHAKPKLAQAADVSINRLNLKVLPYLFQMS
CCCEEEECCCCCCHHHCCEEEEEEHEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]