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The map label for this gene is fusA [C]

Identifier: 167624920

GI number: 167624920

Start: 3649836

End: 3651863

Strand: Reverse

Name: fusA [C]

Synonym: Shal_3006

Alternate gene names: 167624920

Gene position: 3651863-3649836 (Counterclockwise)

Preceding gene: 167624926

Following gene: 167624919

Centisome position: 69.87

GC content: 48.08

Gene sequence:

>2028_bases
ATGGCTGAATTTACTACCGAGCAGATCCGAAATCTGGCTGTGCTTGGACACACTGGATCTGGAAAATCTTCTCTGTTAGA
GGCGCTTCTTTTTCGTGCAGAGGCGATAACATTAAAAGGCAGGGTCGATAAGGGCACTAATCACGCTGATTTCACTGCCC
AAGAAAAATCTCACCGCCATAGTTTAGAACCTTCATTCCTCAATCTCGATTACGCCAATCACCACATCAACATCATAGAC
ACCCCTGGATTACCTGACTTCTTTGGTCGAGCCTTGTTGCCGTTACCAGGCGTTGAATCTGTTGTTTTGGTGATCCACGC
AGGGGTTGGCATAGAGGCGATAACCAAAAGAGCCTTCGAAGCTGCCCGTCGTCAAGGTAAAGCGGTACTCATCGTTATTA
ATCATATTGATGGCAATGAGTCGGCGTTAGCGCCTTTGCTACAAACGATTCAAGCACAGTTTGGTCAGCGATGCTTACCC
GTTAACTTGCCTAATGTTACTGGTGATGGGGTAGTGGATTGCTATTTGCACTGTGACCCACAAGCTCAAACCGCTTTTAT
TGGCGCCGAATGTGCCCGAGATGAATTGGTTGATACCGTGCTTGAAGAAGATGAGCTGTTAATGGAGCTCTATCTTGAGC
AGGGCGAATCGTTAACCCCAGAGCAGCTGCATGCTCCACTTGAAACGGCATTACGCTTAGGCAACTTAGTCCCAGTTTGC
TTTACCAGTGCCGAAAAAGAGATAGGGATCAGTTCGCTGTTAGAGATCCTTATTAAATTAATGCCTAACCCTCTAGAGGC
TAACCCACCGCAATTTGTAAAAGGTTTTGGCGATAACGCTAAAGCTGTCACAGTCAATCAGAATCCTAACGAGCACGTAC
TCGCCCACGTATTTAGGGTCGCAGTTGACCCATTCTTTGGGCGTATGGGGGTATTTCGTTTATATCAAGGCACAATCAAT
GTGGGGATGAAGCTATATATCGGTCAAGGGCGTAAGCCATTTAAAGTGGCTCACCTGATTAAATTACAAGGTGAGAAGCA
TATTGATGTGGCTCAAGCGATACCAGGGAATATCTATGCCATTGCCAAAGTCGAAGAGCTTGAGATCGGTGTGGTGTTGC
ACGACAGTCATGATGAAGATGATTTTCACATGCCAGAGAACGCACTACCTCAGCCTATTTTCGGCCTAGCAGTTTCCCCT
AAACGACGTGGCGATGAACAAAAGTTATCTGAGGTGTTGAATAAACTTGTGGCAGAAGATCCCAGTTTGCGAGTCACTCG
AGGTGAAGCACTGGGGCAAACTCTGCTGCAGGGGCAGGGAGATCTGCATCTGCAAATTGCGCTAGAGAAGGCGCAAACTG
TGTTCAATGTGGATATGGAAACCAATATACCTGCGGTGCCATACAGAGAGACCATCTTAGCCGAGGCAAAGTCACGTTAT
CGCCATAAGAAACAGTCGGGAGGCTCAGGGCAGTTTGGTGAAGTCGAGTTGATGGTTGAGCCGTTGGCCCGTGGCCAAGG
TTTTGAGTTTGTCAGTAAAGTGGTGGGTGGTTCTGTGCCAAGCCAATATATTCCAGCGATAGAGAAAGGCGTGCGCGAAG
CCATGTTAGCGGGAGGGGTAGGTGGTTTCCCGATGCAGGATATTAAAGTCACAGTATTAGATGGTAAACATCATAGCGTG
GATTCTAAGGAGATAGCGTTTGTCATGGCGGGCAAGCGAGCCTTTATGGAGGCTGTTACCTCGGCACAACCTGTGATCCT
TGAGCCTGTCGTTGATATGCAGATCTGCGTAGAGCAGGGCTACGTTGGGGAGATCACCGGTGATATCAGTGCTTCTAGAG
GCATGGTGTGCGGCACTCAGGCGCAAACCAATGGTATGGTTGAGGTGAGTGTGGAAGCGCCGCTTGCAAATGTTGCCGAC
TATTCTACTCGATTAAAATCGATGACTGGAGGAGAGGGGCAGTTCTCAATGAGCTTTAGCCGTTATGATGTGGTTCCCGA
TAGGGTACAGGCTACATTAATGCGTTAA

Upstream 100 bases:

>100_bases
CATTACTAGTTTACAGCGGTCTATACTGACTATAATTTGCTCAACTAAGACTGCAAATAGAAAATGGATTGACTAAATAA
TGTAAAAAAAGGAGGCCAAG

Downstream 100 bases:

>100_bases
TGGGGAGGTTTCGAGGAGTTTGAGCTATTGTGGCACCATTTGAGTTTGTGGCTGTTGTTTTGAATTAAAACAGGCCACAA
TAGCCCATATATCTACGTTC

Product: elongation factor G

Products: GDP; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 675; Mature: 674

Protein sequence:

>675_residues
MAEFTTEQIRNLAVLGHTGSGKSSLLEALLFRAEAITLKGRVDKGTNHADFTAQEKSHRHSLEPSFLNLDYANHHINIID
TPGLPDFFGRALLPLPGVESVVLVIHAGVGIEAITKRAFEAARRQGKAVLIVINHIDGNESALAPLLQTIQAQFGQRCLP
VNLPNVTGDGVVDCYLHCDPQAQTAFIGAECARDELVDTVLEEDELLMELYLEQGESLTPEQLHAPLETALRLGNLVPVC
FTSAEKEIGISSLLEILIKLMPNPLEANPPQFVKGFGDNAKAVTVNQNPNEHVLAHVFRVAVDPFFGRMGVFRLYQGTIN
VGMKLYIGQGRKPFKVAHLIKLQGEKHIDVAQAIPGNIYAIAKVEELEIGVVLHDSHDEDDFHMPENALPQPIFGLAVSP
KRRGDEQKLSEVLNKLVAEDPSLRVTRGEALGQTLLQGQGDLHLQIALEKAQTVFNVDMETNIPAVPYRETILAEAKSRY
RHKKQSGGSGQFGEVELMVEPLARGQGFEFVSKVVGGSVPSQYIPAIEKGVREAMLAGGVGGFPMQDIKVTVLDGKHHSV
DSKEIAFVMAGKRAFMEAVTSAQPVILEPVVDMQICVEQGYVGEITGDISASRGMVCGTQAQTNGMVEVSVEAPLANVAD
YSTRLKSMTGGEGQFSMSFSRYDVVPDRVQATLMR

Sequences:

>Translated_675_residues
MAEFTTEQIRNLAVLGHTGSGKSSLLEALLFRAEAITLKGRVDKGTNHADFTAQEKSHRHSLEPSFLNLDYANHHINIID
TPGLPDFFGRALLPLPGVESVVLVIHAGVGIEAITKRAFEAARRQGKAVLIVINHIDGNESALAPLLQTIQAQFGQRCLP
VNLPNVTGDGVVDCYLHCDPQAQTAFIGAECARDELVDTVLEEDELLMELYLEQGESLTPEQLHAPLETALRLGNLVPVC
FTSAEKEIGISSLLEILIKLMPNPLEANPPQFVKGFGDNAKAVTVNQNPNEHVLAHVFRVAVDPFFGRMGVFRLYQGTIN
VGMKLYIGQGRKPFKVAHLIKLQGEKHIDVAQAIPGNIYAIAKVEELEIGVVLHDSHDEDDFHMPENALPQPIFGLAVSP
KRRGDEQKLSEVLNKLVAEDPSLRVTRGEALGQTLLQGQGDLHLQIALEKAQTVFNVDMETNIPAVPYRETILAEAKSRY
RHKKQSGGSGQFGEVELMVEPLARGQGFEFVSKVVGGSVPSQYIPAIEKGVREAMLAGGVGGFPMQDIKVTVLDGKHHSV
DSKEIAFVMAGKRAFMEAVTSAQPVILEPVVDMQICVEQGYVGEITGDISASRGMVCGTQAQTNGMVEVSVEAPLANVAD
YSTRLKSMTGGEGQFSMSFSRYDVVPDRVQATLMR
>Mature_674_residues
AEFTTEQIRNLAVLGHTGSGKSSLLEALLFRAEAITLKGRVDKGTNHADFTAQEKSHRHSLEPSFLNLDYANHHINIIDT
PGLPDFFGRALLPLPGVESVVLVIHAGVGIEAITKRAFEAARRQGKAVLIVINHIDGNESALAPLLQTIQAQFGQRCLPV
NLPNVTGDGVVDCYLHCDPQAQTAFIGAECARDELVDTVLEEDELLMELYLEQGESLTPEQLHAPLETALRLGNLVPVCF
TSAEKEIGISSLLEILIKLMPNPLEANPPQFVKGFGDNAKAVTVNQNPNEHVLAHVFRVAVDPFFGRMGVFRLYQGTINV
GMKLYIGQGRKPFKVAHLIKLQGEKHIDVAQAIPGNIYAIAKVEELEIGVVLHDSHDEDDFHMPENALPQPIFGLAVSPK
RRGDEQKLSEVLNKLVAEDPSLRVTRGEALGQTLLQGQGDLHLQIALEKAQTVFNVDMETNIPAVPYRETILAEAKSRYR
HKKQSGGSGQFGEVELMVEPLARGQGFEFVSKVVGGSVPSQYIPAIEKGVREAMLAGGVGGFPMQDIKVTVLDGKHHSVD
SKEIAFVMAGKRAFMEAVTSAQPVILEPVVDMQICVEQGYVGEITGDISASRGMVCGTQAQTNGMVEVSVEAPLANVADY
STRLKSMTGGEGQFSMSFSRYDVVPDRVQATLMR

Specific function: This Protein Promotes The GTP-Dependent Translocation Of The Nascent Protein Chain From The A-Site To The P-Site Of The Ribosome. [C]

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=704, Percent_Identity=28.2670454545455, Blast_Score=263, Evalue=6e-70,
Organism=Homo sapiens, GI19923640, Length=722, Percent_Identity=24.2382271468144, Blast_Score=193, Evalue=6e-49,
Organism=Homo sapiens, GI25306287, Length=292, Percent_Identity=27.3972602739726, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI25306283, Length=378, Percent_Identity=24.3386243386243, Blast_Score=96, Evalue=1e-19,
Organism=Escherichia coli, GI1789738, Length=694, Percent_Identity=28.8184438040346, Blast_Score=314, Evalue=9e-87,
Organism=Escherichia coli, GI1790835, Length=519, Percent_Identity=22.5433526011561, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17533571, Length=703, Percent_Identity=26.6002844950213, Blast_Score=271, Evalue=8e-73,
Organism=Caenorhabditis elegans, GI17556745, Length=157, Percent_Identity=28.0254777070064, Blast_Score=80, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323098, Length=697, Percent_Identity=27.8335724533716, Blast_Score=244, Evalue=3e-65,
Organism=Saccharomyces cerevisiae, GI6322359, Length=784, Percent_Identity=22.9591836734694, Blast_Score=194, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6324707, Length=476, Percent_Identity=23.3193277310924, Blast_Score=74, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6320593, Length=476, Percent_Identity=23.3193277310924, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24582462, Length=695, Percent_Identity=28.0575539568345, Blast_Score=287, Evalue=2e-77,
Organism=Drosophila melanogaster, GI221458488, Length=712, Percent_Identity=22.3314606741573, Blast_Score=154, Evalue=2e-37,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 73390; Mature: 73259

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEFTTEQIRNLAVLGHTGSGKSSLLEALLFRAEAITLKGRVDKGTNHADFTAQEKSHRH
CCCCCHHHHHCEEEEECCCCCHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCHHHHHHC
SLEPSFLNLDYANHHINIIDTPGLPDFFGRALLPLPGVESVVLVIHAGVGIEAITKRAFE
CCCCCEEEEEECCCEEEEEECCCCCHHHCCHHCCCCCCCEEEEEEECCCCHHHHHHHHHH
AARRQGKAVLIVINHIDGNESALAPLLQTIQAQFGQRCLPVNLPNVTGDGVVDCYLHCDP
HHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCEEEEEEECCC
QAQTAFIGAECARDELVDTVLEEDELLMELYLEQGESLTPEQLHAPLETALRLGNLVPVC
CCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCHHHHHHHHCCCCEEE
FTSAEKEIGISSLLEILIKLMPNPLEANPPQFVKGFGDNAKAVTVNQNPNEHVLAHVFRV
ECCCCHHCCHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCEEEEECCCCCHHHHHHHHHH
AVDPFFGRMGVFRLYQGTINVGMKLYIGQGRKPFKVAHLIKLQGEKHIDVAQAIPGNIYA
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHEEEECCCCCCCHHHCCCCCEEE
IAKVEELEIGVVLHDSHDEDDFHMPENALPQPIFGLAVSPKRRGDEQKLSEVLNKLVAED
EEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCC
PSLRVTRGEALGQTLLQGQGDLHLQIALEKAQTVFNVDMETNIPAVPYRETILAEAKSRY
CCEEEECCHHHHHHHHCCCCCEEEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHH
RHKKQSGGSGQFGEVELMVEPLARGQGFEFVSKVVGGSVPSQYIPAIEKGVREAMLAGGV
HHHHCCCCCCCCCEEEEEEEHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
GGFPMQDIKVTVLDGKHHSVDSKEIAFVMAGKRAFMEAVTSAQPVILEPVVDMQICVEQG
CCCCCCCEEEEEECCCCCCCCCCEEEEEEECHHHHHHHHHCCCCEEECCHHHHHHHHHCC
YVGEITGDISASRGMVCGTQAQTNGMVEVSVEAPLANVADYSTRLKSMTGGEGQFSMSFS
CCEEEECCCCCCCCCEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEEH
RYDVVPDRVQATLMR
HCCCCHHHHHHHHCC
>Mature Secondary Structure 
AEFTTEQIRNLAVLGHTGSGKSSLLEALLFRAEAITLKGRVDKGTNHADFTAQEKSHRH
CCCCHHHHHCEEEEECCCCCHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCHHHHHHC
SLEPSFLNLDYANHHINIIDTPGLPDFFGRALLPLPGVESVVLVIHAGVGIEAITKRAFE
CCCCCEEEEEECCCEEEEEECCCCCHHHCCHHCCCCCCCEEEEEEECCCCHHHHHHHHHH
AARRQGKAVLIVINHIDGNESALAPLLQTIQAQFGQRCLPVNLPNVTGDGVVDCYLHCDP
HHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCEEEEEEECCC
QAQTAFIGAECARDELVDTVLEEDELLMELYLEQGESLTPEQLHAPLETALRLGNLVPVC
CCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCHHHHHHHHCCCCEEE
FTSAEKEIGISSLLEILIKLMPNPLEANPPQFVKGFGDNAKAVTVNQNPNEHVLAHVFRV
ECCCCHHCCHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCEEEEECCCCCHHHHHHHHHH
AVDPFFGRMGVFRLYQGTINVGMKLYIGQGRKPFKVAHLIKLQGEKHIDVAQAIPGNIYA
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHEEEECCCCCCCHHHCCCCCEEE
IAKVEELEIGVVLHDSHDEDDFHMPENALPQPIFGLAVSPKRRGDEQKLSEVLNKLVAED
EEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCC
PSLRVTRGEALGQTLLQGQGDLHLQIALEKAQTVFNVDMETNIPAVPYRETILAEAKSRY
CCEEEECCHHHHHHHHCCCCCEEEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHH
RHKKQSGGSGQFGEVELMVEPLARGQGFEFVSKVVGGSVPSQYIPAIEKGVREAMLAGGV
HHHHCCCCCCCCCEEEEEEEHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
GGFPMQDIKVTVLDGKHHSVDSKEIAFVMAGKRAFMEAVTSAQPVILEPVVDMQICVEQG
CCCCCCCEEEEEECCCCCCCCCCEEEEEEECHHHHHHHHHCCCCEEECCHHHHHHHHHCC
YVGEITGDISASRGMVCGTQAQTNGMVEVSVEAPLANVADYSTRLKSMTGGEGQFSMSFS
CCEEEECCCCCCCCCEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEEH
RYDVVPDRVQATLMR
HCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]