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The map label for this gene is leuO [H]

Identifier: 167624916

GI number: 167624916

Start: 3644588

End: 3645493

Strand: Reverse

Name: leuO [H]

Synonym: Shal_3002

Alternate gene names: 167624916

Gene position: 3645493-3644588 (Counterclockwise)

Preceding gene: 167624917

Following gene: 167624915

Centisome position: 69.74

GC content: 40.84

Gene sequence:

>906_bases
ATGACACAACAAAAGCAGTTTGATGTAAACCTCTTAAGAGTGTTTTTAGCTGTTTGTCGTACGGGGTCTTATACCTTAGC
AGCTGAGGAGCTTGACTTGACTCAGCCCTCTGTAAGCAATGCAATCAATCGTTTTAAAGCCGTCGTAGGAGAGGAGTTAT
TTGTTCGTGCGGGCCGAAATATTAAACCTACCGCCATGGCGAACTATCTTTTTGAACAGCTCAATGATTCTTTCTGTAAT
ATTGAACAGACAATCAATGGGTTAGAGGGATTTGATCCTAACACTTCTGAACGCCAGTTTGTGGTTCTCGCCAATGATGT
TATTGCCCATATGCTACAAAGGCGGCTTGATGAACTGGTCAAAGATCTACCTATAGAGATTATATTCCGAGAACCACCTG
ATTTTGATAGTGAAATTCTTGAGTTACTTACTCTTGAACAAGCGGATCTCGTTATCGATATCGGCTTGCCTGAAGATAAT
CGCTTTGAACGTAAACTGTTGATACAAGAGGCGGCAGTTTGCGTTGCAAGTAAAGAGCATCCGAGGATACAGGAGTCGAT
ATCTTGGGAGCAGTTTTTTGCAGAAAGGCATGTATTCGTTAAGCTGAGACGATTTAATCGCACCGCAGTTGATATTCTTA
GTGAAGAGGTACTACCTAATCGTAAGGTTTATAGCAGTAAATCATCGATGTTGAGCTTGTTCTCGGCAGTTTCGACCAGT
GATGCTATTGGGGTTGCTCCTAGAAATTATTCAAATGATTTTGAAAAAGTGTTCAATCTTCAGCTACTTCCACTTCCTTT
TAATACTAAGCCACTAGATATTGAACTGGTGTGGAAAAAGAAGCATAACCGTAATCCTGCCCATATTTGGCTTAGAGAGC
AGATAACGTCATTAGTAGATGAATGA

Upstream 100 bases:

>100_bases
AATTAAATAAGTAGGTTAATCCGAGTTTAGATAGTGTGTTAAAGTGAATTATTTGCTTAAATATGGTTCAACGGTTAAGC
GCTAAGATAGAGGGAAAGCA

Downstream 100 bases:

>100_bases
ACGACTAGATCTGGCTAAGGCCTGAACGTAATCAGGACAAAGCGAAATGCAAGCAAAAATTTAACATCAACGCTTCTATA
GAATTGTTTCTATGAACCTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MTQQKQFDVNLLRVFLAVCRTGSYTLAAEELDLTQPSVSNAINRFKAVVGEELFVRAGRNIKPTAMANYLFEQLNDSFCN
IEQTINGLEGFDPNTSERQFVVLANDVIAHMLQRRLDELVKDLPIEIIFREPPDFDSEILELLTLEQADLVIDIGLPEDN
RFERKLLIQEAAVCVASKEHPRIQESISWEQFFAERHVFVKLRRFNRTAVDILSEEVLPNRKVYSSKSSMLSLFSAVSTS
DAIGVAPRNYSNDFEKVFNLQLLPLPFNTKPLDIELVWKKKHNRNPAHIWLREQITSLVDE

Sequences:

>Translated_301_residues
MTQQKQFDVNLLRVFLAVCRTGSYTLAAEELDLTQPSVSNAINRFKAVVGEELFVRAGRNIKPTAMANYLFEQLNDSFCN
IEQTINGLEGFDPNTSERQFVVLANDVIAHMLQRRLDELVKDLPIEIIFREPPDFDSEILELLTLEQADLVIDIGLPEDN
RFERKLLIQEAAVCVASKEHPRIQESISWEQFFAERHVFVKLRRFNRTAVDILSEEVLPNRKVYSSKSSMLSLFSAVSTS
DAIGVAPRNYSNDFEKVFNLQLLPLPFNTKPLDIELVWKKKHNRNPAHIWLREQITSLVDE
>Mature_300_residues
TQQKQFDVNLLRVFLAVCRTGSYTLAAEELDLTQPSVSNAINRFKAVVGEELFVRAGRNIKPTAMANYLFEQLNDSFCNI
EQTINGLEGFDPNTSERQFVVLANDVIAHMLQRRLDELVKDLPIEIIFREPPDFDSEILELLTLEQADLVIDIGLPEDNR
FERKLLIQEAAVCVASKEHPRIQESISWEQFFAERHVFVKLRRFNRTAVDILSEEVLPNRKVYSSKSSMLSLFSAVSTSD
AIGVAPRNYSNDFEKVFNLQLLPLPFNTKPLDIELVWKKKHNRNPAHIWLREQITSLVDE

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=305, Percent_Identity=30.4918032786885, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1786820, Length=284, Percent_Identity=29.5774647887324, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87081766, Length=286, Percent_Identity=23.0769230769231, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789204, Length=244, Percent_Identity=26.2295081967213, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34607; Mature: 34476

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQQKQFDVNLLRVFLAVCRTGSYTLAAEELDLTQPSVSNAINRFKAVVGEELFVRAGRN
CCCCHHCCHHHHHHHHHHHCCCCEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
IKPTAMANYLFEQLNDSFCNIEQTINGLEGFDPNTSERQFVVLANDVIAHMLQRRLDELV
CCHHHHHHHHHHHHCCHHCCHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHH
KDLPIEIIFREPPDFDSEILELLTLEQADLVIDIGLPEDNRFERKLLIQEAAVCVASKEH
HHCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCC
PRIQESISWEQFFAERHVFVKLRRFNRTAVDILSEEVLPNRKVYSSKSSMLSLFSAVSTS
CCHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHCC
DAIGVAPRNYSNDFEKVFNLQLLPLPFNTKPLDIELVWKKKHNRNPAHIWLREQITSLVD
CCCCCCCCCCCHHHHHHHCCEEEECCCCCCCCEEEEEEECCCCCCHHEEEHHHHHHHHHC
E
C
>Mature Secondary Structure 
TQQKQFDVNLLRVFLAVCRTGSYTLAAEELDLTQPSVSNAINRFKAVVGEELFVRAGRN
CCCHHCCHHHHHHHHHHHCCCCEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
IKPTAMANYLFEQLNDSFCNIEQTINGLEGFDPNTSERQFVVLANDVIAHMLQRRLDELV
CCHHHHHHHHHHHHCCHHCCHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHH
KDLPIEIIFREPPDFDSEILELLTLEQADLVIDIGLPEDNRFERKLLIQEAAVCVASKEH
HHCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCC
PRIQESISWEQFFAERHVFVKLRRFNRTAVDILSEEVLPNRKVYSSKSSMLSLFSAVSTS
CCHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHCC
DAIGVAPRNYSNDFEKVFNLQLLPLPFNTKPLDIELVWKKKHNRNPAHIWLREQITSLVD
CCCCCCCCCCCHHHHHHHCCEEEECCCCCCCCEEEEEEECCCCCCHHEEEHHHHHHHHHC
E
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3413113; 1630901; 9278503; 3519576 [H]