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The map label for this gene is rnhB

Identifier: 167624881

GI number: 167624881

Start: 3611111

End: 3611722

Strand: Reverse

Name: rnhB

Synonym: Shal_2967

Alternate gene names: 167624881

Gene position: 3611722-3611111 (Counterclockwise)

Preceding gene: 167624882

Following gene: 167624880

Centisome position: 69.1

GC content: 46.08

Gene sequence:

>612_bases
ATGGCGGTGATTAAAGGTATTACACCAGAGCAGGTGGCTCAAATTTGTATTGGTCACTATGCCGGTGTCGATGAGGTTGG
CCGCGGACCTTTGATTGGCAACGTTGTCACTGCGGCAGTGATTCTTGACCCTAATAATCCTATTGAGGGGTTAAATGATT
CAAAGAAGCTATCAGAGAAAAAGCGCGAGTTACTGTTTGAACAAATTCAGCAAAAAGCCCTAAGCGTCAGTGTTGGCTCA
GCCACCCCAGCAGAAATTGATGAGCTGAATATTTTGCATGCCACTATGCTTGCAATGCAACGAGCTGTTGCTGGTCTTAA
TATTAAGCCTACGAGTGTGTTAGTTGACGGTAACCGCACACCCGATTTTGGCGTTGAAAGCCATGCAATAATTAAAGGTG
ACGGCCTTATCGATGCAATTAGTGCTGCCTCCATTATCGCGAAGGTTGTCCGTGACCGTGAAATGGATGCTCTTGCTTTG
CAGTATCCAGAGTATGGTTTTGACAAGCATAAAGGTTATCCAACTAAGGCCCATTTTGAAGCGTTAACGCAGCACGGCGT
ACTACCTGAGCATCGTAAAAGCTTCAGGCCAGTACGAGAGGCATTAGCTTAG

Upstream 100 bases:

>100_bases
CAATGTATGATCGCTTTATGCAGATGCATAAGAGCCTTCGTTGTGATGCCAGTGCACGTGCTGCAGATGCTGTGATTAAG
TTAGTAGAGGATAAAGTCTA

Downstream 100 bases:

>100_bases
CCTCGAAATCATTTTCCGGTGAAAAATTTGCTCGCTATAGCCTCTTTTTTGCCGGAAAATTAACTCATCAGCCTACGAGA
TTGCAGTTAAACTTGTTTGC

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MAVIKGITPEQVAQICIGHYAGVDEVGRGPLIGNVVTAAVILDPNNPIEGLNDSKKLSEKKRELLFEQIQQKALSVSVGS
ATPAEIDELNILHATMLAMQRAVAGLNIKPTSVLVDGNRTPDFGVESHAIIKGDGLIDAISAASIIAKVVRDREMDALAL
QYPEYGFDKHKGYPTKAHFEALTQHGVLPEHRKSFRPVREALA

Sequences:

>Translated_203_residues
MAVIKGITPEQVAQICIGHYAGVDEVGRGPLIGNVVTAAVILDPNNPIEGLNDSKKLSEKKRELLFEQIQQKALSVSVGS
ATPAEIDELNILHATMLAMQRAVAGLNIKPTSVLVDGNRTPDFGVESHAIIKGDGLIDAISAASIIAKVVRDREMDALAL
QYPEYGFDKHKGYPTKAHFEALTQHGVLPEHRKSFRPVREALA
>Mature_202_residues
AVIKGITPEQVAQICIGHYAGVDEVGRGPLIGNVVTAAVILDPNNPIEGLNDSKKLSEKKRELLFEQIQQKALSVSVGSA
TPAEIDELNILHATMLAMQRAVAGLNIKPTSVLVDGNRTPDFGVESHAIIKGDGLIDAISAASIIAKVVRDREMDALALQ
YPEYGFDKHKGYPTKAHFEALTQHGVLPEHRKSFRPVREALA

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=182, Percent_Identity=65.9340659340659, Blast_Score=244, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_SHEHH (B0TP69)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001675175.1
- ProteinModelPortal:   B0TP69
- SMR:   B0TP69
- GeneID:   5906833
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_2967
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- ProtClustDB:   PRK00015
- BioCyc:   SHAL458817:SHAL_2967-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 21905; Mature: 21774

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVIKGITPEQVAQICIGHYAGVDEVGRGPLIGNVVTAAVILDPNNPIEGLNDSKKLSEK
CCEECCCCHHHHHHHHHHHHCCHHHCCCCCCHHHHHEEEEEECCCCCCCCCCCHHHHHHH
KRELLFEQIQQKALSVSVGSATPAEIDELNILHATMLAMQRAVAGLNIKPTSVLVDGNRT
HHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCC
PDFGVESHAIIKGDGLIDAISAASIIAKVVRDREMDALALQYPEYGFDKHKGYPTKAHFE
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCHHEEECCCCCCCCCCCCCCHHHHH
ALTQHGVLPEHRKSFRPVREALA
HHHHCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AVIKGITPEQVAQICIGHYAGVDEVGRGPLIGNVVTAAVILDPNNPIEGLNDSKKLSEK
CEECCCCHHHHHHHHHHHHCCHHHCCCCCCHHHHHEEEEEECCCCCCCCCCCHHHHHHH
KRELLFEQIQQKALSVSVGSATPAEIDELNILHATMLAMQRAVAGLNIKPTSVLVDGNRT
HHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCC
PDFGVESHAIIKGDGLIDAISAASIIAKVVRDREMDALALQYPEYGFDKHKGYPTKAHFE
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCHHEEECCCCCCCCCCCCCCHHHHH
ALTQHGVLPEHRKSFRPVREALA
HHHHCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA