Click here to switch to the map view.

The map label for this gene is tdk [H]

Identifier: 167624855

GI number: 167624855

Start: 3573745

End: 3574323

Strand: Reverse

Name: tdk [H]

Synonym: Shal_2941

Alternate gene names: 167624855

Gene position: 3574323-3573745 (Counterclockwise)

Preceding gene: 167624857

Following gene: 167624854

Centisome position: 68.38

GC content: 45.25

Gene sequence:

>579_bases
TTGGCGCAGCTATATTTCTATTACTCAGCCATGAATGCGGGTAAATCAACTTCGTTATTGCAGTCTTCTTATAATTACCG
CGAACGCGGTATGCATACCTTAGTCATGACAGCCTCAATAGATGACCGCTATGGTGTGGGTAAAGTGGCTTCTCGTCTTG
GTATCGAAACCGAGGCGCAAGTATTTGGTAGTAATGACAATCTTACTCAGATGATCAGCACTAGCCATGCAGACAAGACC
TTACACTGTATCTTAATTGATGAATCTCAGTTTTTAAGTAAAGAGCAGGTGAAACAGCTGACCTATGTGGTTGATATCTT
AGATATCCCGGTGTTGTGCTATGGCCTTAAAACCGATTTCCAGGGTGAGTTGTTCAGCGGTAGCCACTATTTACTCGCAT
GGGCAGATAAGCTGGTAGAGCTTAAAACCATCTGTCACTGCGGCCGTAAAGCCAACATGGTGGTACGCCTCGATGGCGAT
GGCAAACCGATGCGTGAAGGTGAGCAGGTGGCCATTGGCGGTAACGAAAGTTACGAGTCTGTATGCCGAAAGCATTTTAG
AGAATTTATCTGGGATTAG

Upstream 100 bases:

>100_bases
ACTTTCCCGTTGATAGGTGTCACTGAATGGTGTCTGTAAGGTGATTTTTTATTGTGAATAGTGCTAAACTAGGCGTGAAC
TCACCTTTAAGGATTTTAGT

Downstream 100 bases:

>100_bases
GCTTTATCGCCCCTAGAGGATAAGAGAGGCTAACACTGTCAAGGTGTTAGCCTTTTTTAATGCCTATTTACTTGAGATAG
GATTATAAGTGGGGCTTTTG

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MAQLYFYYSAMNAGKSTSLLQSSYNYRERGMHTLVMTASIDDRYGVGKVASRLGIETEAQVFGSNDNLTQMISTSHADKT
LHCILIDESQFLSKEQVKQLTYVVDILDIPVLCYGLKTDFQGELFSGSHYLLAWADKLVELKTICHCGRKANMVVRLDGD
GKPMREGEQVAIGGNESYESVCRKHFREFIWD

Sequences:

>Translated_192_residues
MAQLYFYYSAMNAGKSTSLLQSSYNYRERGMHTLVMTASIDDRYGVGKVASRLGIETEAQVFGSNDNLTQMISTSHADKT
LHCILIDESQFLSKEQVKQLTYVVDILDIPVLCYGLKTDFQGELFSGSHYLLAWADKLVELKTICHCGRKANMVVRLDGD
GKPMREGEQVAIGGNESYESVCRKHFREFIWD
>Mature_191_residues
AQLYFYYSAMNAGKSTSLLQSSYNYRERGMHTLVMTASIDDRYGVGKVASRLGIETEAQVFGSNDNLTQMISTSHADKTL
HCILIDESQFLSKEQVKQLTYVVDILDIPVLCYGLKTDFQGELFSGSHYLLAWADKLVELKTICHCGRKANMVVRLDGDG
KPMREGEQVAIGGNESYESVCRKHFREFIWD

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787490, Length=188, Percent_Identity=68.0851063829787, Blast_Score=280, Evalue=3e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 21700; Mature: 21569

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLYFYYSAMNAGKSTSLLQSSYNYRERGMHTLVMTASIDDRYGVGKVASRLGIETEAQ
CCEEEEEEEECCCCCHHHHHHHHCCHHHCCCEEEEEEECCCCCCCHHHHHHHHCCCCHHE
VFGSNDNLTQMISTSHADKTLHCILIDESQFLSKEQVKQLTYVVDILDIPVLCYGLKTDF
EECCCCCHHHHHHCCCCCCEEEEEEECCHHHCCHHHHHHHHHHHHHHHHHHEEEECCCCC
QGELFSGSHYLLAWADKLVELKTICHCGRKANMVVRLDGDGKPMREGEQVAIGGNESYES
CCEEECCCEEEEHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEECCCCCHHH
VCRKHFREFIWD
HHHHHHHHHHCC
>Mature Secondary Structure 
AQLYFYYSAMNAGKSTSLLQSSYNYRERGMHTLVMTASIDDRYGVGKVASRLGIETEAQ
CEEEEEEEECCCCCHHHHHHHHCCHHHCCCEEEEEEECCCCCCCHHHHHHHHCCCCHHE
VFGSNDNLTQMISTSHADKTLHCILIDESQFLSKEQVKQLTYVVDILDIPVLCYGLKTDF
EECCCCCHHHHHHCCCCCCEEEEEEECCHHHCCHHHHHHHHHHHHHHHHHHEEEECCCCC
QGELFSGSHYLLAWADKLVELKTICHCGRKANMVVRLDGDGKPMREGEQVAIGGNESYES
CCEEECCCEEEEHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEECCCCCHHH
VCRKHFREFIWD
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]