Click here to switch to the map view.

The map label for this gene is ackA [H]

Identifier: 167624656

GI number: 167624656

Start: 3322284

End: 3323492

Strand: Reverse

Name: ackA [H]

Synonym: Shal_2738

Alternate gene names: 167624656

Gene position: 3323492-3322284 (Counterclockwise)

Preceding gene: 167624657

Following gene: 167624655

Centisome position: 63.58

GC content: 44.25

Gene sequence:

>1209_bases
ATGTCAAATAAATATGTCTTAGTGCTGAACTGTGGCAGTTCTTCGCTAAAGTTTGCCGTTATCGATGCGATCAGTGGAGA
AGATCTACTCAGTGGTCTAAGTGAATGCTTTGGTCTTGAAGATGCCTGCATTAAGTGGAAAACCCGAGTCGGACAACAAG
AGAGTAAGCATCAAGAGAGCTTAGGAGCCTTTAGTGCTCACACTGAAGCGATGGCCTATATTGTGGATACAATTCTTGCT
GCCCACCCAACGCTTAAGCAACAGATCCTGGCCGTAGGACACCGAGTCGTACATGGCGGTGAACAATTTAGTGGTTCGGT
TATTATTAACGATGAGGTACTGCAAGGTATAGAGGCCTGCGCCACGCTTGCTCCATTACATAATCCGGCGCACATTATCG
GTATTTTAGCCGCTAAGGTTGCCTTTCCACAGCTTGCGCAGATTGCCGTGTTTGACACTGCATTTCATCAAACTATGCCT
CAAAAAGCCTTTATTTATGCGTTGCCATACCAGCTTTATCGTGAACATAGTATTCGACGCTTTGGTATGCACGGCACTAG
CCATCGCTATATTTGCCAAACAGCGGCTAAGACATTAGGGATTGCTGTTGAGGACCTAAACTTGATCAGTGCACACCTTG
GTAATGGTGCTTCAGTTACCGCCATTAAAGCTGGAATAAGTGTCGATACTTCGATGGGAATGACGCCTCTTGAAGGGGTG
GTAATGGGGACTCGCTGTGGTGATTTAGACCCTTCAATCATTTTTTACTTAGTGCAAAACCTAGGTTATAGCCTAAAAGA
AGTCGAAGATATGATGAATAAACAAAGTGGTTTATTAGGAATTTCTGAGCTTACCAATGATTGCCGCGGTATTGAGGAGG
GACATGCTAATGGACATAAAGGCGCGAGCTTGGCACTGGATATATTTTGCTATCGTTTAGCAAAGTATATCGCTTCATAC
ACAGTGCCATTAGGACGTATTGATGCACTAGTGTTTACTGGTGGCATTGGTGAAAACTCGGCATTAATTCGCCAAAAAGT
TATTGAGTTACTCTCTATTTTCAATTTTAAGTTAGACAGACAGCGAAACCTTGCGGCCCGTTTTGGGCAACAAGGGCAGA
TCACTGCTGATACTGGTCCTGTTGCGATGGTGATCCCAACAAATGAAGAGTGGGTTATCGCTCAAGATGCACTGAAGCTA
ATCGATTAA

Upstream 100 bases:

>100_bases
TAGTGATTAATCAAATTAGTTAGCGCAGTAGCTATTGGGCAGTCAATACATTCATTTAAACAAAATACTTGGGCTTTCCC
CATGTGTTATAGGATTACTC

Downstream 100 bases:

>100_bases
GGATTTTGCGTTGGTCGTTGGAAACGTCAGGCGTGCAGTGCACGTTAAATTGAGATGAAAAACAGCAAAACTAGAGCAGA
TTAATATGCCACGTAAAATA

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MSNKYVLVLNCGSSSLKFAVIDAISGEDLLSGLSECFGLEDACIKWKTRVGQQESKHQESLGAFSAHTEAMAYIVDTILA
AHPTLKQQILAVGHRVVHGGEQFSGSVIINDEVLQGIEACATLAPLHNPAHIIGILAAKVAFPQLAQIAVFDTAFHQTMP
QKAFIYALPYQLYREHSIRRFGMHGTSHRYICQTAAKTLGIAVEDLNLISAHLGNGASVTAIKAGISVDTSMGMTPLEGV
VMGTRCGDLDPSIIFYLVQNLGYSLKEVEDMMNKQSGLLGISELTNDCRGIEEGHANGHKGASLALDIFCYRLAKYIASY
TVPLGRIDALVFTGGIGENSALIRQKVIELLSIFNFKLDRQRNLAARFGQQGQITADTGPVAMVIPTNEEWVIAQDALKL
ID

Sequences:

>Translated_402_residues
MSNKYVLVLNCGSSSLKFAVIDAISGEDLLSGLSECFGLEDACIKWKTRVGQQESKHQESLGAFSAHTEAMAYIVDTILA
AHPTLKQQILAVGHRVVHGGEQFSGSVIINDEVLQGIEACATLAPLHNPAHIIGILAAKVAFPQLAQIAVFDTAFHQTMP
QKAFIYALPYQLYREHSIRRFGMHGTSHRYICQTAAKTLGIAVEDLNLISAHLGNGASVTAIKAGISVDTSMGMTPLEGV
VMGTRCGDLDPSIIFYLVQNLGYSLKEVEDMMNKQSGLLGISELTNDCRGIEEGHANGHKGASLALDIFCYRLAKYIASY
TVPLGRIDALVFTGGIGENSALIRQKVIELLSIFNFKLDRQRNLAARFGQQGQITADTGPVAMVIPTNEEWVIAQDALKL
ID
>Mature_401_residues
SNKYVLVLNCGSSSLKFAVIDAISGEDLLSGLSECFGLEDACIKWKTRVGQQESKHQESLGAFSAHTEAMAYIVDTILAA
HPTLKQQILAVGHRVVHGGEQFSGSVIINDEVLQGIEACATLAPLHNPAHIIGILAAKVAFPQLAQIAVFDTAFHQTMPQ
KAFIYALPYQLYREHSIRRFGMHGTSHRYICQTAAKTLGIAVEDLNLISAHLGNGASVTAIKAGISVDTSMGMTPLEGVV
MGTRCGDLDPSIIFYLVQNLGYSLKEVEDMMNKQSGLLGISELTNDCRGIEEGHANGHKGASLALDIFCYRLAKYIASYT
VPLGRIDALVFTGGIGENSALIRQKVIELLSIFNFKLDRQRNLAARFGQQGQITADTGPVAMVIPTNEEWVIAQDALKLI
D

Specific function: Involved In The Activation Of Acetate To Acetyl CoA And The Secretion Of Acetate. During Anaerobic Growth Of The Organism, This Enzyme Is Also Involved In The Synthesis Of Most Of The ATP Formed Catabolically. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788633, Length=403, Percent_Identity=57.5682382133995, Blast_Score=485, Evalue=1e-138,
Organism=Escherichia coli, GI145693184, Length=396, Percent_Identity=43.4343434343434, Blast_Score=332, Evalue=3e-92,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 43473; Mature: 43341

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKYVLVLNCGSSSLKFAVIDAISGEDLLSGLSECFGLEDACIKWKTRVGQQESKHQES
CCCCEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHH
LGAFSAHTEAMAYIVDTILAAHPTLKQQILAVGHRVVHGGEQFSGSVIINDEVLQGIEAC
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHHH
ATLAPLHNPAHIIGILAAKVAFPQLAQIAVFDTAFHQTMPQKAFIYALPYQLYREHSIRR
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHH
FGMHGTSHRYICQTAAKTLGIAVEDLNLISAHLGNGASVTAIKAGISVDTSMGMTPLEGV
HCCCCCCCHHHHHHHHHHHCEEHHHHHHHHHHCCCCCEEEEEEECCEECCCCCCCCCCCE
VMGTRCGDLDPSIIFYLVQNLGYSLKEVEDMMNKQSGLLGISELTNDCRGIEEGHANGHK
EEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEHHHHHHHHCCCHHCCCCCCC
GASLALDIFCYRLAKYIASYTVPLGRIDALVFTGGIGENSALIRQKVIELLSIFNFKLDR
CCHHHHHHHHHHHHHHHHHHCCCHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCC
QRNLAARFGQQGQITADTGPVAMVIPTNEEWVIAQDALKLID
HHHHHHHCCCCCEEEECCCCEEEEEECCCCEEEHHHHHHHCC
>Mature Secondary Structure 
SNKYVLVLNCGSSSLKFAVIDAISGEDLLSGLSECFGLEDACIKWKTRVGQQESKHQES
CCCEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHH
LGAFSAHTEAMAYIVDTILAAHPTLKQQILAVGHRVVHGGEQFSGSVIINDEVLQGIEAC
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHHH
ATLAPLHNPAHIIGILAAKVAFPQLAQIAVFDTAFHQTMPQKAFIYALPYQLYREHSIRR
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHH
FGMHGTSHRYICQTAAKTLGIAVEDLNLISAHLGNGASVTAIKAGISVDTSMGMTPLEGV
HCCCCCCCHHHHHHHHHHHCEEHHHHHHHHHHCCCCCEEEEEEECCEECCCCCCCCCCCE
VMGTRCGDLDPSIIFYLVQNLGYSLKEVEDMMNKQSGLLGISELTNDCRGIEEGHANGHK
EEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEHHHHHHHHCCCHHCCCCCCC
GASLALDIFCYRLAKYIASYTVPLGRIDALVFTGGIGENSALIRQKVIELLSIFNFKLDR
CCHHHHHHHHHHHHHHHHHHCCCHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCC
QRNLAARFGQQGQITADTGPVAMVIPTNEEWVIAQDALKLID
HHHHHHHCCCCCEEEECCCCEEEEEECCCCEEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA