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The map label for this gene is macB [H]

Identifier: 167624370

GI number: 167624370

Start: 2952598

End: 2953911

Strand: Reverse

Name: macB [H]

Synonym: Shal_2447

Alternate gene names: 167624370

Gene position: 2953911-2952598 (Counterclockwise)

Preceding gene: 167624371

Following gene: 167624369

Centisome position: 56.51

GC content: 48.25

Gene sequence:

>1314_bases
ATGACCGTTAACAGAGCATCGGTGAACCTGGTTAAACCGCTTAAAAATGACGCCTCTAGAAAATCATCGGTGCTTATCGC
CGTCTATTGGGAGGGCATTAAACAAGCGTTCGATGAAATGCGTCATCACAAACTGCGGACCTCCTTGACTCTACTCGGCA
TGATATTTGGTGTCGGTGCTGTTATCGCAATGCTTAGCGTTGGTGAAGGTGCCGAGCGTGAAGCATTAAAGATGATCGAG
TCAATGGGCGTGAATAATTTGGTGGTTAATGCGCGCAGCGCAGAAGGGGAAGCCCTTAAGTCGGTGCGAGAGCACAGCAT
AGGGCTGAGCCTGCGAGACATAGAGAGCGCCCGTGATACCTTGCCATTTGTGGAGAACTGGAGTGCTGAAAAATATGTCA
AAGTGTTCAGTCTGTTTAGTCTCAAAGGCCGCAGTGATGCACAAGTTGTCGGTGTCACTCCAAGTTATTTTGAGCTTAGT
TCACTGCCGTTAGGTGAGGGGCGTACACTCAATGATACAGATGAAGCCTACTACCAACAGGTCGCCGTGTTAGGGCCAGA
AGCCGCCAGAAGTTTATTTCCTCAAGGCAATGCGATAAACAGTTTGATTAAAGTGAATCATCAGTGGTTTACCGTTGTTG
GCGTCTTGCAAGAAAAAGAGGGCTCTAAGTCTAGTATCCAGGGGGTAAAGCTCGGTGGTGAACGTAATCAAGTGTTTATT
CCGTTAACAACAGCACTTAAAAAGATGCAGTTTAAGAGCTTAGAGAATGAACTCGATGCGTTTAAGTTGGCTTTAGCCGA
TGGGATAGATCCTTCGCTCGCCGCCAAAAGTTTGCAACATCTATTAAATCGGCGCCATGGCGGAGAGAAAGATTTTGATG
TGGTCGTTCCGGCCGATCTACTGGCACAACACCAGAAAACCCAACAAATTTTTAATATCGTGATGGCGTGTGTTGCAGGG
ATCTCATTGCTCGTGGGTGGCATAGGTATTATGAATATCATGCTAGCAACCATTTTAGAGCGCACCGGGGAAATAGGTCT
GTTACGCGCCTTAGGAGCGAAACGTAAAGACATTGCCCGCCAGTTTTTAATCGAAAGTATCGCTATCTCGGCCACGGGCG
GCATTATCGGCATCGGGGTGGGATTATTGTTGGCGCTAATTATCTCTTCTGCCGCGGGATGGCCTGTGGCGTGGTCTCCG
TTTGCTATCTTATTAGCACTGGGGGTGTGTATGACCATCGGTGTAGGCTTTGGACTCTACCCCGCGAACAAGGCTGCCAA
GCTTGATCCCATTGTTGCGCTACAGCGAGATTAA

Upstream 100 bases:

>100_bases
TTACACTTGGGAATCGTAGCCTCAACAGAACGGTGATCACCGAAGGGTTGAAGCAAGGGGATACCATTGCATTGACTACG
CCACCGAAAAGGAATCGTGT

Downstream 100 bases:

>100_bases
GTTGGCGATTCTGTAAAAATAACCCGCGATTTTTATCGCGGGTTTTTATTTTCAGCCTTATGCCACCGACTTCAGAAGGT
GGATTCTTTACTGCTTGAGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MTVNRASVNLVKPLKNDASRKSSVLIAVYWEGIKQAFDEMRHHKLRTSLTLLGMIFGVGAVIAMLSVGEGAEREALKMIE
SMGVNNLVVNARSAEGEALKSVREHSIGLSLRDIESARDTLPFVENWSAEKYVKVFSLFSLKGRSDAQVVGVTPSYFELS
SLPLGEGRTLNDTDEAYYQQVAVLGPEAARSLFPQGNAINSLIKVNHQWFTVVGVLQEKEGSKSSIQGVKLGGERNQVFI
PLTTALKKMQFKSLENELDAFKLALADGIDPSLAAKSLQHLLNRRHGGEKDFDVVVPADLLAQHQKTQQIFNIVMACVAG
ISLLVGGIGIMNIMLATILERTGEIGLLRALGAKRKDIARQFLIESIAISATGGIIGIGVGLLLALIISSAAGWPVAWSP
FAILLALGVCMTIGVGFGLYPANKAAKLDPIVALQRD

Sequences:

>Translated_437_residues
MTVNRASVNLVKPLKNDASRKSSVLIAVYWEGIKQAFDEMRHHKLRTSLTLLGMIFGVGAVIAMLSVGEGAEREALKMIE
SMGVNNLVVNARSAEGEALKSVREHSIGLSLRDIESARDTLPFVENWSAEKYVKVFSLFSLKGRSDAQVVGVTPSYFELS
SLPLGEGRTLNDTDEAYYQQVAVLGPEAARSLFPQGNAINSLIKVNHQWFTVVGVLQEKEGSKSSIQGVKLGGERNQVFI
PLTTALKKMQFKSLENELDAFKLALADGIDPSLAAKSLQHLLNRRHGGEKDFDVVVPADLLAQHQKTQQIFNIVMACVAG
ISLLVGGIGIMNIMLATILERTGEIGLLRALGAKRKDIARQFLIESIAISATGGIIGIGVGLLLALIISSAAGWPVAWSP
FAILLALGVCMTIGVGFGLYPANKAAKLDPIVALQRD
>Mature_436_residues
TVNRASVNLVKPLKNDASRKSSVLIAVYWEGIKQAFDEMRHHKLRTSLTLLGMIFGVGAVIAMLSVGEGAEREALKMIES
MGVNNLVVNARSAEGEALKSVREHSIGLSLRDIESARDTLPFVENWSAEKYVKVFSLFSLKGRSDAQVVGVTPSYFELSS
LPLGEGRTLNDTDEAYYQQVAVLGPEAARSLFPQGNAINSLIKVNHQWFTVVGVLQEKEGSKSSIQGVKLGGERNQVFIP
LTTALKKMQFKSLENELDAFKLALADGIDPSLAAKSLQHLLNRRHGGEKDFDVVVPADLLAQHQKTQQIFNIVMACVAGI
SLLVGGIGIMNIMLATILERTGEIGLLRALGAKRKDIARQFLIESIAISATGGIIGIGVGLLLALIISSAAGWPVAWSPF
AILLALGVCMTIGVGFGLYPANKAAKLDPIVALQRD

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=418, Percent_Identity=31.3397129186603, Blast_Score=177, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 47054; Mature: 46923

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVNRASVNLVKPLKNDASRKSSVLIAVYWEGIKQAFDEMRHHKLRTSLTLLGMIFGVGA
CCCCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIAMLSVGEGAEREALKMIESMGVNNLVVNARSAEGEALKSVREHSIGLSLRDIESARDT
HHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHC
LPFVENWSAEKYVKVFSLFSLKGRSDAQVVGVTPSYFELSSLPLGEGRTLNDTDEAYYQQ
CCHHHCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHCCCCCCCCCCCCCHHHHHHHH
VAVLGPEAARSLFPQGNAINSLIKVNHQWFTVVGVLQEKEGSKSSIQGVKLGGERNQVFI
HHHCCHHHHHHHCCCCHHHHHHHHHCCHHEEHHHHHHHCCCCHHHCCCEEECCCCCEEEE
PLTTALKKMQFKSLENELDAFKLALADGIDPSLAAKSLQHLLNRRHGGEKDFDVVVPADL
EHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECHHH
LAQHQKTQQIFNIVMACVAGISLLVGGIGIMNIMLATILERTGEIGLLRALGAKRKDIAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHH
QFLIESIAISATGGIIGIGVGLLLALIISSAAGWPVAWSPFAILLALGVCMTIGVGFGLY
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
PANKAAKLDPIVALQRD
CCCCCCCCCCCEEECCC
>Mature Secondary Structure 
TVNRASVNLVKPLKNDASRKSSVLIAVYWEGIKQAFDEMRHHKLRTSLTLLGMIFGVGA
CCCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIAMLSVGEGAEREALKMIESMGVNNLVVNARSAEGEALKSVREHSIGLSLRDIESARDT
HHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHC
LPFVENWSAEKYVKVFSLFSLKGRSDAQVVGVTPSYFELSSLPLGEGRTLNDTDEAYYQQ
CCHHHCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHCCCCCCCCCCCCCHHHHHHHH
VAVLGPEAARSLFPQGNAINSLIKVNHQWFTVVGVLQEKEGSKSSIQGVKLGGERNQVFI
HHHCCHHHHHHHCCCCHHHHHHHHHCCHHEEHHHHHHHCCCCHHHCCCEEECCCCCEEEE
PLTTALKKMQFKSLENELDAFKLALADGIDPSLAAKSLQHLLNRRHGGEKDFDVVVPADL
EHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECHHH
LAQHQKTQQIFNIVMACVAGISLLVGGIGIMNIMLATILERTGEIGLLRALGAKRKDIAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHH
QFLIESIAISATGGIIGIGVGLLLALIISSAAGWPVAWSPFAILLALGVCMTIGVGFGLY
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
PANKAAKLDPIVALQRD
CCCCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA