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The map label for this gene is udk

Identifier: 167624303

GI number: 167624303

Start: 2879242

End: 2879880

Strand: Reverse

Name: udk

Synonym: Shal_2379

Alternate gene names: 167624303

Gene position: 2879880-2879242 (Counterclockwise)

Preceding gene: 167624304

Following gene: 167624302

Centisome position: 55.1

GC content: 43.04

Gene sequence:

>639_bases
ATGAATTCTAAAGATTGTGTTGTAATTGGTATTGCGGGTGCGTCAGCATCAGGTAAGAGTCTTATCGCTAAAACGATTTA
TGAAGAACTTTGCCGTGATCTAGGTACAGATCAAATTGGTGTGATAGCTGAAGATGCTTATTACCGCGACCAAGGTCATC
TGTCGATGGATCAACGTGTACTGACAAATTATGACCATCCAAAAGCATTAGATCATGAGCTACTGTGTACGCACCTACGT
GCACTTAAACAGGGTCATGCTGTTGATATTCCTGTTTACAGCTATAACGATCATACTCGTACAGACGAGAAAGTGACGCT
TACCCCTAAGAAAGTCATTATCCTTGAAGGCATCTTGTTATTGACCGATCCCGCTCTGCGAAAAGAGATGGACGCTTCTG
TATTTATGGATACGCCTCTGGACATTTGCTTTATGCGTCGTCTATCTCGTGATGTCGCCGAGCGTGGTAGAACGATGGAG
TCTGTAATGCAGCAATATACAGAGACTGTACGTCCAATGTTTTTGCAGTTTATTGAACCATCAAAACAGTATGCTGATAT
CATCGTACCGCGCGGTGGTAAAAACCGAATCGCAACAGATATTCTAAAGGCGCGTATACAGCACCTACTGGCGAAATAA

Upstream 100 bases:

>100_bases
ATCGTGAAATCGCAAGAAAGGTTGGGGCTCAGCTTGCGTTATGTCAAGCACAGCCTAAAGTATCAATTAGCATGTCTGAT
GACGAATAAGGTCTATTTAA

Downstream 100 bases:

>100_bases
GGCAACTTAAAACATAAGGGACTCTAGCGAACATGCGTTTAACAGTTCTAGAGATTGAAGCGTGCTTTGCTAATGCCTAA
GGTTTGGGTAAATGGACAGC

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MNSKDCVVIGIAGASASGKSLIAKTIYEELCRDLGTDQIGVIAEDAYYRDQGHLSMDQRVLTNYDHPKALDHELLCTHLR
ALKQGHAVDIPVYSYNDHTRTDEKVTLTPKKVIILEGILLLTDPALRKEMDASVFMDTPLDICFMRRLSRDVAERGRTME
SVMQQYTETVRPMFLQFIEPSKQYADIIVPRGGKNRIATDILKARIQHLLAK

Sequences:

>Translated_212_residues
MNSKDCVVIGIAGASASGKSLIAKTIYEELCRDLGTDQIGVIAEDAYYRDQGHLSMDQRVLTNYDHPKALDHELLCTHLR
ALKQGHAVDIPVYSYNDHTRTDEKVTLTPKKVIILEGILLLTDPALRKEMDASVFMDTPLDICFMRRLSRDVAERGRTME
SVMQQYTETVRPMFLQFIEPSKQYADIIVPRGGKNRIATDILKARIQHLLAK
>Mature_212_residues
MNSKDCVVIGIAGASASGKSLIAKTIYEELCRDLGTDQIGVIAEDAYYRDQGHLSMDQRVLTNYDHPKALDHELLCTHLR
ALKQGHAVDIPVYSYNDHTRTDEKVTLTPKKVIILEGILLLTDPALRKEMDASVFMDTPLDICFMRRLSRDVAERGRTME
SVMQQYTETVRPMFLQFIEPSKQYADIIVPRGGKNRIATDILKARIQHLLAK

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family

Homologues:

Organism=Homo sapiens, GI301129207, Length=210, Percent_Identity=38.5714285714286, Blast_Score=160, Evalue=6e-40,
Organism=Homo sapiens, GI57863312, Length=210, Percent_Identity=38.5714285714286, Blast_Score=160, Evalue=9e-40,
Organism=Homo sapiens, GI18699734, Length=217, Percent_Identity=35.9447004608295, Blast_Score=156, Evalue=1e-38,
Organism=Homo sapiens, GI13899253, Length=211, Percent_Identity=33.6492890995261, Blast_Score=134, Evalue=5e-32,
Organism=Homo sapiens, GI209863022, Length=148, Percent_Identity=29.0540540540541, Blast_Score=78, Evalue=5e-15,
Organism=Escherichia coli, GI87082034, Length=209, Percent_Identity=70.8133971291866, Blast_Score=313, Evalue=5e-87,
Organism=Caenorhabditis elegans, GI17539892, Length=211, Percent_Identity=36.9668246445498, Blast_Score=149, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17539894, Length=211, Percent_Identity=36.9668246445498, Blast_Score=149, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71981181, Length=215, Percent_Identity=34.4186046511628, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6324339, Length=151, Percent_Identity=34.4370860927152, Blast_Score=107, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24649624, Length=214, Percent_Identity=37.3831775700935, Blast_Score=156, Evalue=1e-38,
Organism=Drosophila melanogaster, GI221458995, Length=213, Percent_Identity=37.0892018779343, Blast_Score=155, Evalue=2e-38,
Organism=Drosophila melanogaster, GI28573516, Length=204, Percent_Identity=39.2156862745098, Blast_Score=153, Evalue=7e-38,
Organism=Drosophila melanogaster, GI28573514, Length=204, Percent_Identity=39.2156862745098, Blast_Score=153, Evalue=7e-38,
Organism=Drosophila melanogaster, GI28573512, Length=204, Percent_Identity=39.2156862745098, Blast_Score=153, Evalue=7e-38,
Organism=Drosophila melanogaster, GI45550449, Length=204, Percent_Identity=39.2156862745098, Blast_Score=153, Evalue=8e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URK_SHEHH (B0TJ03)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001674597.1
- ProteinModelPortal:   B0TJ03
- SMR:   B0TJ03
- GeneID:   5905384
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_2379
- HOGENOM:   HBG527126
- OMA:   DQIGVIA
- ProtClustDB:   PRK05480
- BioCyc:   SHAL458817:SHAL_2379-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00551
- InterPro:   IPR006083
- InterPro:   IPR000764
- PANTHER:   PTHR10285:SF6
- PRINTS:   PR00988
- TIGRFAMs:   TIGR00235

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.48

Molecular weight: Translated: 23975; Mature: 23975

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSKDCVVIGIAGASASGKSLIAKTIYEELCRDLGTDQIGVIAEDAYYRDQGHLSMDQRV
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCEECCCCCCCHHHHH
LTNYDHPKALDHELLCTHLRALKQGHAVDIPVYSYNDHTRTDEKVTLTPKKVIILEGILL
HHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCEEEECCCEEHHHHHHHH
LTDPALRKEMDASVFMDTPLDICFMRRLSRDVAERGRTMESVMQQYTETVRPMFLQFIEP
HCCHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
SKQYADIIVPRGGKNRIATDILKARIQHLLAK
CHHHHEEEECCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNSKDCVVIGIAGASASGKSLIAKTIYEELCRDLGTDQIGVIAEDAYYRDQGHLSMDQRV
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCEECCCCCCCHHHHH
LTNYDHPKALDHELLCTHLRALKQGHAVDIPVYSYNDHTRTDEKVTLTPKKVIILEGILL
HHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCEEEECCCEEHHHHHHHH
LTDPALRKEMDASVFMDTPLDICFMRRLSRDVAERGRTMESVMQQYTETVRPMFLQFIEP
HCCHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
SKQYADIIVPRGGKNRIATDILKARIQHLLAK
CHHHHEEEECCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA