Click here to switch to the map view.

The map label for this gene is prc [H]

Identifier: 167624288

GI number: 167624288

Start: 2863479

End: 2865524

Strand: Reverse

Name: prc [H]

Synonym: Shal_2364

Alternate gene names: 167624288

Gene position: 2865524-2863479 (Counterclockwise)

Preceding gene: 167624289

Following gene: 167624287

Centisome position: 54.82

GC content: 43.84

Gene sequence:

>2046_bases
ATGCGAAAACTTTCTCTGGCTGTATCCATTGCCGGTATTTTTGTCGGATTCTCGGCGTGGGCTGTAAGCCCTACTATTCA
ATTCAGCGAGTTGCCCGCTCTTAAGCAGGAGCCTCAACATAAAGTCGCCAGCAAACGTGTGACAGGTTTGTTCACTCGCT
CTCACTATCATCGTTTTGATATGGATGACGCTTTCTCTGAGCAGGTATTTAACCGGTATCTGAAGCAATTAGACTATCGT
AAGAATGTCTTACTGCAGGCAGATGTTGACAGTTTCAAAGCATATTCATCTGATTTTGATGATATGTTGAAAACTGGCGA
TTTGAATCAAGCTTATAAGATGTTCGAACTGGTTCAGAAGCGTCGCTATGAACGATTTGCCTATGCATTGTCTTTGCTCG
ATGAGGAGATGGCATTTGATGTTCCTGGTGACGTATATGAATACGATCGCGAAGATGCAAATTGGCCAAAAACTGAAGCT
GAGCTAAATGAACTTTGGCGTCAACGTGTTAAATACGATGCCTTGAATCTCTCTCTTACGGGTAAAAACTGGGATGAGAT
CGTTGAAGTCCTAGAGAAACGTTATAACAATGCCATTAAGCGTTTAAGCCAAACTCATAGCGAAGATGTCTTCCAAGGCG
TCATGAATGCATTTGCCCGTACGGTAGAGCCTCACACCAGTTACCTTTCCCCTCGAAATGCTGAGCGTTTCCAGATGGAA
ATGAACTTGAGCTTAGAAGGCATTGGTGCGGTGCTTCAAGTCGATGATGACTATACCGTGATCAAGAGTCTGGTTGCAGG
CGGCCCCGCAGCATCAAGTGAAAAGTTATCACCTGAAGATAGAATTATTGGTGTCGGTCAAGAAGGCAAAGAAATCGTCG
ATGTTATCGGTTGGCGACTTGATGATGTCGTCGAACTGATTAAAGGTCCAAAGGGCAGTAAGGTTGTTCTTGAGATTTTA
CCTAAGAAAGGCGGCAGCAGCGCGAAAACGTTTGAATTGACAATTGTTCGCGATAAAATTCGACTAGAAGATAGAGCCGC
AACCTCTAAAGTGATTGAGCCGACAGACGGTCCTTATGCAAATCGTAAAGTGGGTGTGATTCAAATACCTGGCTTCTATA
TGGATCTGTCGAAAGACGTTTCTAAAGAACTTGCCGAATTAAAAGAAGCTAAAGTCGAAGGCATTATTATCGACCTTCGT
GGTAATGGCGGCGGTGCGTTAACAGAAGCGACCTTGCTAACAGGCTTATTTATCGAGCAAGGCCCCGTGGTTCAGATTCG
AGATGCGAACGGCCGAGTATCACAAAATCGCGATAATGATGGACGTGTGACTTATGATGGTCCGTTAACTGTCATGGTTG
ATAGATACAGTGCATCTGCTTCTGAAATTTTTGCGGCAGCACTTCAAGATTATGATCGTGCACTGATTGTTGGTGAGTCG
ACCTTTGGTAAAGGTACGGTACAGCAGCATAAGAGTCTGGGTCGTATCTATGATATGTACGAAAAGCCTATCGGTCACGT
GCAGTACACGATTGCCAAGTTCTACCGTATTAATGGTGGAAGCACCCAGCTTAAAGGGGTTACCCCTGATATTCCGTTCC
CAAGTGCCCTAGAGCCGGGAGAGTACGGTGAAGCTGAAGAAGAAAATGCGTTGCCGTGGGACAAAGTGCCTGTAGCACAA
TACGGTACGCTTGATGAAATTTATCCGCAGCTTATTCAGAGCTTAGACGGTAAGCATAAAGAGCGTATCAAGTCTGACGT
TGAATTTGGTTACATTTTCCAAGATATCGCTGAGTTTAAAGAAAATCATGATGATAAAACGGTTTCTTTAGTTAAGACTG
AACGTTTAGCTGAGCGGGATACAAACGATAAGAAACAACTGGATCGTGCTAACGACAGGCTTGTAAGAGAAGGCCAAGAA
AAAGTTAAGTCATTAGACGATATTTCTGACGACGTCGAAGTTGCCGATGCTTTCTTAGATGAAACTGCCTATATCACGCT
AGATTTGGCGGATATTGAGAAACTCGCTAAGAATCAAAAAAAGTAA

Upstream 100 bases:

>100_bases
AGATGTTCAAGTTCAGTTAGACTCTGGTTTAACCATCAAAGTTAGAGCTGAACATATACTGCTGTAATGGCTTAATAGCA
CCTAAAGGAGTAACTTGTTG

Downstream 100 bases:

>100_bases
AACAGACTCAATAAAAAAACGCGCTTTATGCGCGTTTTTTTTAATTCAAAATTAATAAATTAGAGGTTTATTCATGTCAC
AGCCCCAAGCTAAATTCCTC

Product: carboxy-terminal protease

Products: NA

Alternate protein names: C-terminal-processing peptidase; PRC protein; Protease Re [H]

Number of amino acids: Translated: 681; Mature: 681

Protein sequence:

>681_residues
MRKLSLAVSIAGIFVGFSAWAVSPTIQFSELPALKQEPQHKVASKRVTGLFTRSHYHRFDMDDAFSEQVFNRYLKQLDYR
KNVLLQADVDSFKAYSSDFDDMLKTGDLNQAYKMFELVQKRRYERFAYALSLLDEEMAFDVPGDVYEYDREDANWPKTEA
ELNELWRQRVKYDALNLSLTGKNWDEIVEVLEKRYNNAIKRLSQTHSEDVFQGVMNAFARTVEPHTSYLSPRNAERFQME
MNLSLEGIGAVLQVDDDYTVIKSLVAGGPAASSEKLSPEDRIIGVGQEGKEIVDVIGWRLDDVVELIKGPKGSKVVLEIL
PKKGGSSAKTFELTIVRDKIRLEDRAATSKVIEPTDGPYANRKVGVIQIPGFYMDLSKDVSKELAELKEAKVEGIIIDLR
GNGGGALTEATLLTGLFIEQGPVVQIRDANGRVSQNRDNDGRVTYDGPLTVMVDRYSASASEIFAAALQDYDRALIVGES
TFGKGTVQQHKSLGRIYDMYEKPIGHVQYTIAKFYRINGGSTQLKGVTPDIPFPSALEPGEYGEAEEENALPWDKVPVAQ
YGTLDEIYPQLIQSLDGKHKERIKSDVEFGYIFQDIAEFKENHDDKTVSLVKTERLAERDTNDKKQLDRANDRLVREGQE
KVKSLDDISDDVEVADAFLDETAYITLDLADIEKLAKNQKK

Sequences:

>Translated_681_residues
MRKLSLAVSIAGIFVGFSAWAVSPTIQFSELPALKQEPQHKVASKRVTGLFTRSHYHRFDMDDAFSEQVFNRYLKQLDYR
KNVLLQADVDSFKAYSSDFDDMLKTGDLNQAYKMFELVQKRRYERFAYALSLLDEEMAFDVPGDVYEYDREDANWPKTEA
ELNELWRQRVKYDALNLSLTGKNWDEIVEVLEKRYNNAIKRLSQTHSEDVFQGVMNAFARTVEPHTSYLSPRNAERFQME
MNLSLEGIGAVLQVDDDYTVIKSLVAGGPAASSEKLSPEDRIIGVGQEGKEIVDVIGWRLDDVVELIKGPKGSKVVLEIL
PKKGGSSAKTFELTIVRDKIRLEDRAATSKVIEPTDGPYANRKVGVIQIPGFYMDLSKDVSKELAELKEAKVEGIIIDLR
GNGGGALTEATLLTGLFIEQGPVVQIRDANGRVSQNRDNDGRVTYDGPLTVMVDRYSASASEIFAAALQDYDRALIVGES
TFGKGTVQQHKSLGRIYDMYEKPIGHVQYTIAKFYRINGGSTQLKGVTPDIPFPSALEPGEYGEAEEENALPWDKVPVAQ
YGTLDEIYPQLIQSLDGKHKERIKSDVEFGYIFQDIAEFKENHDDKTVSLVKTERLAERDTNDKKQLDRANDRLVREGQE
KVKSLDDISDDVEVADAFLDETAYITLDLADIEKLAKNQKK
>Mature_681_residues
MRKLSLAVSIAGIFVGFSAWAVSPTIQFSELPALKQEPQHKVASKRVTGLFTRSHYHRFDMDDAFSEQVFNRYLKQLDYR
KNVLLQADVDSFKAYSSDFDDMLKTGDLNQAYKMFELVQKRRYERFAYALSLLDEEMAFDVPGDVYEYDREDANWPKTEA
ELNELWRQRVKYDALNLSLTGKNWDEIVEVLEKRYNNAIKRLSQTHSEDVFQGVMNAFARTVEPHTSYLSPRNAERFQME
MNLSLEGIGAVLQVDDDYTVIKSLVAGGPAASSEKLSPEDRIIGVGQEGKEIVDVIGWRLDDVVELIKGPKGSKVVLEIL
PKKGGSSAKTFELTIVRDKIRLEDRAATSKVIEPTDGPYANRKVGVIQIPGFYMDLSKDVSKELAELKEAKVEGIIIDLR
GNGGGALTEATLLTGLFIEQGPVVQIRDANGRVSQNRDNDGRVTYDGPLTVMVDRYSASASEIFAAALQDYDRALIVGES
TFGKGTVQQHKSLGRIYDMYEKPIGHVQYTIAKFYRINGGSTQLKGVTPDIPFPSALEPGEYGEAEEENALPWDKVPVAQ
YGTLDEIYPQLIQSLDGKHKERIKSDVEFGYIFQDIAEFKENHDDKTVSLVKTERLAERDTNDKKQLDRANDRLVREGQE
KVKSLDDISDDVEVADAFLDETAYITLDLADIEKLAKNQKK

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=676, Percent_Identity=54.4378698224852, Blast_Score=706, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 76718; Mature: 76718

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLSLAVSIAGIFVGFSAWAVSPTIQFSELPALKQEPQHKVASKRVTGLFTRSHYHRFD
CCCHHHHHHHHHHHHHHHHHCCCCCEEHHHCCCHHCCHHHHHHHHHHHHHHHHHHCCCCC
MDDAFSEQVFNRYLKQLDYRKNVLLQADVDSFKAYSSDFDDMLKTGDLNQAYKMFELVQK
CCHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHH
RRYERFAYALSLLDEEMAFDVPGDVYEYDREDANWPKTEAELNELWRQRVKYDALNLSLT
HHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEC
GKNWDEIVEVLEKRYNNAIKRLSQTHSEDVFQGVMNAFARTVEPHTSYLSPRNAERFQME
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCEEEE
MNLSLEGIGAVLQVDDDYTVIKSLVAGGPAASSEKLSPEDRIIGVGQEGKEIVDVIGWRL
ECCCEECCCEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHCCCH
DDVVELIKGPKGSKVVLEILPKKGGSSAKTFELTIVRDKIRLEDRAATSKVIEPTDGPYA
HHHHHHHCCCCCCEEEEEEECCCCCCCCEEEEEEEEECHHHHHHHHHHCCCCCCCCCCCC
NRKVGVIQIPGFYMDLSKDVSKELAELKEAKVEGIIIDLRGNGGGALTEATLLTGLFIEQ
CCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHCCC
GPVVQIRDANGRVSQNRDNDGRVTYDGPLTVMVDRYSASASEIFAAALQDYDRALIVGES
CCEEEEECCCCCCCCCCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECC
TFGKGTVQQHKSLGRIYDMYEKPIGHVQYTIAKFYRINGGSTQLKGVTPDIPFPSALEPG
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHEEHHHEEECCCCEEECCCCCCCCCCCCCCCC
EYGEAEEENALPWDKVPVAQYGTLDEIYPQLIQSLDGKHKERIKSDVEFGYIFQDIAEFK
CCCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHH
ENHDDKTVSLVKTERLAERDTNDKKQLDRANDRLVREGQEKVKSLDDISDDVEVADAFLD
HCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
ETAYITLDLADIEKLAKNQKK
CCEEEEEEHHHHHHHHHCCCC
>Mature Secondary Structure
MRKLSLAVSIAGIFVGFSAWAVSPTIQFSELPALKQEPQHKVASKRVTGLFTRSHYHRFD
CCCHHHHHHHHHHHHHHHHHCCCCCEEHHHCCCHHCCHHHHHHHHHHHHHHHHHHCCCCC
MDDAFSEQVFNRYLKQLDYRKNVLLQADVDSFKAYSSDFDDMLKTGDLNQAYKMFELVQK
CCHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHH
RRYERFAYALSLLDEEMAFDVPGDVYEYDREDANWPKTEAELNELWRQRVKYDALNLSLT
HHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEC
GKNWDEIVEVLEKRYNNAIKRLSQTHSEDVFQGVMNAFARTVEPHTSYLSPRNAERFQME
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCEEEE
MNLSLEGIGAVLQVDDDYTVIKSLVAGGPAASSEKLSPEDRIIGVGQEGKEIVDVIGWRL
ECCCEECCCEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHCCCH
DDVVELIKGPKGSKVVLEILPKKGGSSAKTFELTIVRDKIRLEDRAATSKVIEPTDGPYA
HHHHHHHCCCCCCEEEEEEECCCCCCCCEEEEEEEEECHHHHHHHHHHCCCCCCCCCCCC
NRKVGVIQIPGFYMDLSKDVSKELAELKEAKVEGIIIDLRGNGGGALTEATLLTGLFIEQ
CCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHCCC
GPVVQIRDANGRVSQNRDNDGRVTYDGPLTVMVDRYSASASEIFAAALQDYDRALIVGES
CCEEEEECCCCCCCCCCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECC
TFGKGTVQQHKSLGRIYDMYEKPIGHVQYTIAKFYRINGGSTQLKGVTPDIPFPSALEPG
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHEEHHHEEECCCCEEECCCCCCCCCCCCCCCC
EYGEAEEENALPWDKVPVAQYGTLDEIYPQLIQSLDGKHKERIKSDVEFGYIFQDIAEFK
CCCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHH
ENHDDKTVSLVKTERLAERDTNDKKQLDRANDRLVREGQEKVKSLDDISDDVEVADAFLD
HCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
ETAYITLDLADIEKLAKNQKK
CCEEEEEEHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1856173; 1729701; 9097040; 9278503; 1447154; 10049386; 7499412; 8576225 [H]