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The map label for this gene is hlyB [H]

Identifier: 167624228

GI number: 167624228

Start: 2789399

End: 2791039

Strand: Direct

Name: hlyB [H]

Synonym: Shal_2304

Alternate gene names: 167624228

Gene position: 2789399-2791039 (Clockwise)

Preceding gene: 167624226

Following gene: 167624229

Centisome position: 53.37

GC content: 42.23

Gene sequence:

>1641_bases
ATGATCGCTCTACTCAGACAATTTACGATTCTACAACGCTTAATTTTAATGCTAATGCTGGCAGCAATCGGCACAGTTTG
CTTCGCCAGTTTTTCAATAAACGAACAGTACAATAACCTTGTGGCGCAGAAATGGTTGCAAAACGACGGTCAAATCAACA
CAGCAATTAGTTTGATTGAAGCAAATAAAAAGCAAGTCGATGCTCAAAAGATCAGCTTAGCGACAGCACAAGCAACGACA
ACAGAGCTTATTAACCAAATACATTTTGGCAACGATGGCTATTTCATCATATTAGATCGTAGTCATACCATTATCGCTAA
CGGTGCAGATCCTCTCTCTATTTCTAAAAACGTAAACTCACTCTCTCACTCTCAAGCAGCTGTAAACCTCGACACATTAT
TGAATGAGTCAAAAAATCAAGCCGTCGCTAAAGCGAAAATCGATTTTCCTAACCCCACGACCGGAAAATTGGAACCTAAA
CTTGTAGAAGTTAGACAATATGAGCCTTGGGGGTGGACGGTTATTACAGGAAGTTACATGAGTGACATTGACGATGTCAT
GTATTTAATGGCTTTCGATTACCTCATCATCATGCTAATGATCTCTATCCCTATTTTCTTGTTCTTCTTAGTTCTCAACA
TCTCTATTACTGCCCCCTTAAAAGAAGCGATTAGCGCAATGAAAGATATTGCTCAAGGAGAAGGTGATTTAACCAAGAAG
CTACCAACCAAAGGTAAAGATGAAGTCGCGGAGCTTGCCGAAGCATTTAATTTATTTGTTATCAAAATTAGAGATATGGT
CGCAGAGCTTCAACCTATAGGCGATGATTTAGACCTAGATGCTCAGCGCTTACTCAACGCCGCTGAAGAATCCAATGATA
GTGTCGAGCACCTACATAGAGAAACCTCAAGTGTCGCAACGGCAATCAACCAGATGCTGTCGACCACTCAAGAAATGGCC
AGTAACACCAACCAAGCGGCAGAAGCGGCTAATAGTGTAAAACATCAAGCCCAACAGAGTATGTCTATGATGGACGCCAC
GCTTGATAACTCTAAGCATCTCGCAGATGAACTTAAAAGTGCTCAGCAGATCACTCATGCTCTGGGTAGCTCATCATCGC
AGATTGGCAACATTTTGGATGTTATTCGAGGTATTGCCGATCAAACTAATCTACTGGCACTTAATGCCGCAATTGAAGCT
GCCCGAGCAGGTAGTCATGGCAGAGGATTTGCGGTCGTCGCGGATGAAGTTAGAGCCTTAGCTAACCGTACTCAGGATTC
AACTAATGAGATCCAAAACATCATTAAAGAGATCCAATCGGGTGTAAATAGTGTTGTTGCCAGTAATGAGCAAAATCAAA
GTCAGTCTCAACAAGTTCAGACCCAAGCCAAAGAGGTAAGTGACTCCTTGTCTGACATTCTCAGTCTGATAGCACATATT
AGCGACATGAACACCCAACTTGCCAGTGCAACAGAAGAGCAATCTATCGTCACTGAAGAGATTAACCGTAACATCTGCGC
CATAACCGAATTAACTGAAGTGTCAGTCAAAGCAAATGAGAGCAACCACAATGCTGCTATGTCACTGCAAAATATCAGTA
AAGATTGCGCTCGCACACTCGGTCAATTCAAGGTCAAGTAA

Upstream 100 bases:

>100_bases
TAGAGTTAACATTTTTAAAATAAACAGAGCCTTACTGTTCCCATACTATGGCATAAAGAGTAAGTTTAACTCACGTATTC
GTCAGCAGAATAATAATGAT

Downstream 100 bases:

>100_bases
TATAACACTACGAACCCGAGGGGCGGTAATTGCCCCTCACGCCCTTTGCAAATTATGTTAAGCTAAATTCTATGAAAAGT
TCTCTTAAAGTGAATTGAAT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MIALLRQFTILQRLILMLMLAAIGTVCFASFSINEQYNNLVAQKWLQNDGQINTAISLIEANKKQVDAQKISLATAQATT
TELINQIHFGNDGYFIILDRSHTIIANGADPLSISKNVNSLSHSQAAVNLDTLLNESKNQAVAKAKIDFPNPTTGKLEPK
LVEVRQYEPWGWTVITGSYMSDIDDVMYLMAFDYLIIMLMISIPIFLFFLVLNISITAPLKEAISAMKDIAQGEGDLTKK
LPTKGKDEVAELAEAFNLFVIKIRDMVAELQPIGDDLDLDAQRLLNAAEESNDSVEHLHRETSSVATAINQMLSTTQEMA
SNTNQAAEAANSVKHQAQQSMSMMDATLDNSKHLADELKSAQQITHALGSSSSQIGNILDVIRGIADQTNLLALNAAIEA
ARAGSHGRGFAVVADEVRALANRTQDSTNEIQNIIKEIQSGVNSVVASNEQNQSQSQQVQTQAKEVSDSLSDILSLIAHI
SDMNTQLASATEEQSIVTEEINRNICAITELTEVSVKANESNHNAAMSLQNISKDCARTLGQFKVK

Sequences:

>Translated_546_residues
MIALLRQFTILQRLILMLMLAAIGTVCFASFSINEQYNNLVAQKWLQNDGQINTAISLIEANKKQVDAQKISLATAQATT
TELINQIHFGNDGYFIILDRSHTIIANGADPLSISKNVNSLSHSQAAVNLDTLLNESKNQAVAKAKIDFPNPTTGKLEPK
LVEVRQYEPWGWTVITGSYMSDIDDVMYLMAFDYLIIMLMISIPIFLFFLVLNISITAPLKEAISAMKDIAQGEGDLTKK
LPTKGKDEVAELAEAFNLFVIKIRDMVAELQPIGDDLDLDAQRLLNAAEESNDSVEHLHRETSSVATAINQMLSTTQEMA
SNTNQAAEAANSVKHQAQQSMSMMDATLDNSKHLADELKSAQQITHALGSSSSQIGNILDVIRGIADQTNLLALNAAIEA
ARAGSHGRGFAVVADEVRALANRTQDSTNEIQNIIKEIQSGVNSVVASNEQNQSQSQQVQTQAKEVSDSLSDILSLIAHI
SDMNTQLASATEEQSIVTEEINRNICAITELTEVSVKANESNHNAAMSLQNISKDCARTLGQFKVK
>Mature_546_residues
MIALLRQFTILQRLILMLMLAAIGTVCFASFSINEQYNNLVAQKWLQNDGQINTAISLIEANKKQVDAQKISLATAQATT
TELINQIHFGNDGYFIILDRSHTIIANGADPLSISKNVNSLSHSQAAVNLDTLLNESKNQAVAKAKIDFPNPTTGKLEPK
LVEVRQYEPWGWTVITGSYMSDIDDVMYLMAFDYLIIMLMISIPIFLFFLVLNISITAPLKEAISAMKDIAQGEGDLTKK
LPTKGKDEVAELAEAFNLFVIKIRDMVAELQPIGDDLDLDAQRLLNAAEESNDSVEHLHRETSSVATAINQMLSTTQEMA
SNTNQAAEAANSVKHQAQQSMSMMDATLDNSKHLADELKSAQQITHALGSSSSQIGNILDVIRGIADQTNLLALNAAIEA
ARAGSHGRGFAVVADEVRALANRTQDSTNEIQNIIKEIQSGVNSVVASNEQNQSQSQQVQTQAKEVSDSLSDILSLIAHI
SDMNTQLASATEEQSIVTEEINRNICAITELTEVSVKANESNHNAAMSLQNISKDCARTLGQFKVK

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=324, Percent_Identity=29.9382716049383, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1788195, Length=299, Percent_Identity=29.0969899665552, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788194, Length=327, Percent_Identity=28.4403669724771, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI1787690, Length=363, Percent_Identity=29.4765840220386, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1789453, Length=345, Percent_Identity=25.7971014492754, Blast_Score=97, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59541; Mature: 59541

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALLRQFTILQRLILMLMLAAIGTVCFASFSINEQYNNLVAQKWLQNDGQINTAISLIE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
ANKKQVDAQKISLATAQATTTELINQIHFGNDGYFIILDRSHTIIANGADPLSISKNVNS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEECCCCCCCCCCCHHH
LSHSQAAVNLDTLLNESKNQAVAKAKIDFPNPTTGKLEPKLVEVRQYEPWGWTVITGSYM
HHHHHHHHHHHHHHCCCCCHHHHEEEECCCCCCCCCCCCHHHHHEECCCCCEEEEECHHH
SDIDDVMYLMAFDYLIIMLMISIPIFLFFLVLNISITAPLKEAISAMKDIAQGEGDLTKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHC
LPTKGKDEVAELAEAFNLFVIKIRDMVAELQPIGDDLDLDAQRLLNAAEESNDSVEHLHR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHH
ETSSVATAINQMLSTTQEMASNTNQAAEAANSVKHQAQQSMSMMDATLDNSKHLADELKS
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AQQITHALGSSSSQIGNILDVIRGIADQTNLLALNAAIEAARAGSHGRGFAVVADEVRAL
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCCCEEHHHHHHHHH
ANRTQDSTNEIQNIIKEIQSGVNSVVASNEQNQSQSQQVQTQAKEVSDSLSDILSLIAHI
HHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDMNTQLASATEEQSIVTEEINRNICAITELTEVSVKANESNHNAAMSLQNISKDCARTL
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHEEECCCCCCHHHHHHHHHHHHHHHHH
GQFKVK
HCCCCC
>Mature Secondary Structure
MIALLRQFTILQRLILMLMLAAIGTVCFASFSINEQYNNLVAQKWLQNDGQINTAISLIE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
ANKKQVDAQKISLATAQATTTELINQIHFGNDGYFIILDRSHTIIANGADPLSISKNVNS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEECCCCCCCCCCCHHH
LSHSQAAVNLDTLLNESKNQAVAKAKIDFPNPTTGKLEPKLVEVRQYEPWGWTVITGSYM
HHHHHHHHHHHHHHCCCCCHHHHEEEECCCCCCCCCCCCHHHHHEECCCCCEEEEECHHH
SDIDDVMYLMAFDYLIIMLMISIPIFLFFLVLNISITAPLKEAISAMKDIAQGEGDLTKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHC
LPTKGKDEVAELAEAFNLFVIKIRDMVAELQPIGDDLDLDAQRLLNAAEESNDSVEHLHR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHH
ETSSVATAINQMLSTTQEMASNTNQAAEAANSVKHQAQQSMSMMDATLDNSKHLADELKS
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AQQITHALGSSSSQIGNILDVIRGIADQTNLLALNAAIEAARAGSHGRGFAVVADEVRAL
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCCCEEHHHHHHHHH
ANRTQDSTNEIQNIIKEIQSGVNSVVASNEQNQSQSQQVQTQAKEVSDSLSDILSLIAHI
HHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDMNTQLASATEEQSIVTEEINRNICAITELTEVSVKANESNHNAAMSLQNISKDCARTL
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHEEECCCCCCHHHHHHHHHHHHHHHHH
GQFKVK
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]