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The map label for this gene is pgm [H]

Identifier: 167624162

GI number: 167624162

Start: 2714411

End: 2716051

Strand: Reverse

Name: pgm [H]

Synonym: Shal_2238

Alternate gene names: 167624162

Gene position: 2716051-2714411 (Counterclockwise)

Preceding gene: 167624163

Following gene: 167624161

Centisome position: 51.96

GC content: 45.76

Gene sequence:

>1641_bases
TTGGCTACACACAAGAGAGCTGGATTGATTGCTGAGCAAAAGGATTTGGTCAATATCCCAAAACTCGTTAGCCTATATTA
TTGCTTAACACCCGATGTGAATGAGGTTAGCCAAAAGGTCACGTTTGGCACGTCGGGGCATCGCGGCAGTGCGGTACAAA
AAAGCTTTAATGAAATGCATATCCTTGCTATTGCACAAGCGGTTGCTGATTATCGAAAACAAGCCAATATTACGGGTAAG
TTGATTTTAGGTATCGATACTCACGCTTTATCGCAGCCTGCAGCCATTTCGGTTGTTGAAGTATTAGTTGCAAACCAAAT
CAGCGTTGTGGTCCATCAAAATGATGGTTTTACCCCCACACCAGTGGTGTCTCATGCGATTATTTGTGCCAACAAGAGTC
CCGCCGAGGGCTTGGTTGATGGCCTAATCGTGACACCTTCCCATAACCCACCGCAAGATGGAGGTATTAAATATAATCCG
CCTCACGGTGGGCCCGCAGAAGGTGAGATCACCACTTGGGTGGAAAACCGAGCTAACCAATACTTAGCCAGTCAGTTGGA
TGGGGTTAAGCGTGTCAGTTACGCTCATGCAGTAGAAAGCCAGTACTTGCTTGAGCAAGACTTAATTACTCCTTATGTCG
AAGATCTGTGTAATGTCATCGATATGCAGGCGATTGCAGATGCTAAGATCCGCTTGGGCATCGATCCTCTCGGTGGGTCA
GGGATCCATTATTGGACTCCGATTGCTCAGCATTACGGGATCGATATCACTGTGCTTAACGAGAAAGTCGACCCGAGTTT
TAGCTTTATGCCACTCGATAAAGACGGCAAGATCCGCATGGACTGCTCGTCACCTTATGCGATGGCGGGGTTATTAGCGC
ATAAAGATAATTTTGATCTTTGTTTGGGTAATGATCCTGACTTTGACCGTCACGGTATTGTCTGTCCAGGCAGTGGATTG
ATGAATCCAAATCATTTTCTTGCGGTTGCAATTGATTATCTGCTAACCCATCGTCCTAACTGGACCGAACAGATGGTGAT
CGGTAAGACTTTAGTGTCGAGCGCGATGATAGATAAAGTCTGTGCGATGCATAATAAGCAAATGTCTGAAGTTCCGGTGG
GCTTTAAGTGGTTCGTTGAGGGACTTGCCAATAGCGATTTTGCCTTTGGTGGCGAAGAAAGTGCAGGCGCAGCATTTTTA
AGAACCGATGGCAGCACTTGGTGTACAGATAAAGACGGATTTATTTTGTGTCTACTGGCCGCTGAAATGCTTGCCGTGAC
AGGTAAAACACCTCAGCAACGTTACGATGAACTAGAAGTTCAATTTGGTAAGAGTTTTTATCAGCGTATTGATAGCCCTG
TGAGCCTAGAAGACAAAGCTAAGTTTTCGACGATCTCTGCTGATGCAATTGTTGCTGATACCCTAGCGGGTGACACTATA
TTACAAAAACTGACTCATGCCCCAGGTAACGGCGCAGCCATTGGTGGCATTAAAGTCGTAACAGAGAAAGGCTGGTTTGC
TGCTCGTCCATCGGGTACCGAAGCCTTGTTTAAGCTTTATGGTGAAAGCTTCGTAAGCCTAGAACATTTAACTCAGTTGC
TAAAAGATGCACAGCAGATTGTGGCTGCTGCATTAAGATAA

Upstream 100 bases:

>100_bases
TACCGATATCATAGAGAAAATCTAACGCCGTATCGCGTTAATGTAAAACATTTAAACTTGCCGTGCTTAACGTCATCACG
GCAATAAAAGGAGAAGGAAC

Downstream 100 bases:

>100_bases
ATGGATCGTTTGTTATTTAGAGTCAAGTATCAAACGCAGTAGGCACCTTTGATAGCTTGAGCATATAGCTTGAAACCTTT
GGTGCATGAGGGATTGCAAA

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 546; Mature: 545

Protein sequence:

>546_residues
MATHKRAGLIAEQKDLVNIPKLVSLYYCLTPDVNEVSQKVTFGTSGHRGSAVQKSFNEMHILAIAQAVADYRKQANITGK
LILGIDTHALSQPAAISVVEVLVANQISVVVHQNDGFTPTPVVSHAIICANKSPAEGLVDGLIVTPSHNPPQDGGIKYNP
PHGGPAEGEITTWVENRANQYLASQLDGVKRVSYAHAVESQYLLEQDLITPYVEDLCNVIDMQAIADAKIRLGIDPLGGS
GIHYWTPIAQHYGIDITVLNEKVDPSFSFMPLDKDGKIRMDCSSPYAMAGLLAHKDNFDLCLGNDPDFDRHGIVCPGSGL
MNPNHFLAVAIDYLLTHRPNWTEQMVIGKTLVSSAMIDKVCAMHNKQMSEVPVGFKWFVEGLANSDFAFGGEESAGAAFL
RTDGSTWCTDKDGFILCLLAAEMLAVTGKTPQQRYDELEVQFGKSFYQRIDSPVSLEDKAKFSTISADAIVADTLAGDTI
LQKLTHAPGNGAAIGGIKVVTEKGWFAARPSGTEALFKLYGESFVSLEHLTQLLKDAQQIVAAALR

Sequences:

>Translated_546_residues
MATHKRAGLIAEQKDLVNIPKLVSLYYCLTPDVNEVSQKVTFGTSGHRGSAVQKSFNEMHILAIAQAVADYRKQANITGK
LILGIDTHALSQPAAISVVEVLVANQISVVVHQNDGFTPTPVVSHAIICANKSPAEGLVDGLIVTPSHNPPQDGGIKYNP
PHGGPAEGEITTWVENRANQYLASQLDGVKRVSYAHAVESQYLLEQDLITPYVEDLCNVIDMQAIADAKIRLGIDPLGGS
GIHYWTPIAQHYGIDITVLNEKVDPSFSFMPLDKDGKIRMDCSSPYAMAGLLAHKDNFDLCLGNDPDFDRHGIVCPGSGL
MNPNHFLAVAIDYLLTHRPNWTEQMVIGKTLVSSAMIDKVCAMHNKQMSEVPVGFKWFVEGLANSDFAFGGEESAGAAFL
RTDGSTWCTDKDGFILCLLAAEMLAVTGKTPQQRYDELEVQFGKSFYQRIDSPVSLEDKAKFSTISADAIVADTLAGDTI
LQKLTHAPGNGAAIGGIKVVTEKGWFAARPSGTEALFKLYGESFVSLEHLTQLLKDAQQIVAAALR
>Mature_545_residues
ATHKRAGLIAEQKDLVNIPKLVSLYYCLTPDVNEVSQKVTFGTSGHRGSAVQKSFNEMHILAIAQAVADYRKQANITGKL
ILGIDTHALSQPAAISVVEVLVANQISVVVHQNDGFTPTPVVSHAIICANKSPAEGLVDGLIVTPSHNPPQDGGIKYNPP
HGGPAEGEITTWVENRANQYLASQLDGVKRVSYAHAVESQYLLEQDLITPYVEDLCNVIDMQAIADAKIRLGIDPLGGSG
IHYWTPIAQHYGIDITVLNEKVDPSFSFMPLDKDGKIRMDCSSPYAMAGLLAHKDNFDLCLGNDPDFDRHGIVCPGSGLM
NPNHFLAVAIDYLLTHRPNWTEQMVIGKTLVSSAMIDKVCAMHNKQMSEVPVGFKWFVEGLANSDFAFGGEESAGAAFLR
TDGSTWCTDKDGFILCLLAAEMLAVTGKTPQQRYDELEVQFGKSFYQRIDSPVSLEDKAKFSTISADAIVADTLAGDTIL
QKLTHAPGNGAAIGGIKVVTEKGWFAARPSGTEALFKLYGESFVSLEHLTQLLKDAQQIVAAALR

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI290463102, Length=392, Percent_Identity=24.7448979591837, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI21361621, Length=434, Percent_Identity=25.1152073732719, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI133922562, Length=420, Percent_Identity=23.3333333333333, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1786904, Length=546, Percent_Identity=57.8754578754579, Blast_Score=659, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17535441, Length=549, Percent_Identity=25.3187613843352, Blast_Score=103, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6322722, Length=442, Percent_Identity=24.8868778280543, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17864244, Length=436, Percent_Identity=25.2293577981651, Blast_Score=87, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005852 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 59089; Mature: 58958

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATHKRAGLIAEQKDLVNIPKLVSLYYCLTPDVNEVSQKVTFGTSGHRGSAVQKSFNEMH
CCCCCCCCCCCCCHHHCCHHHHHHHHHCCCCCHHHHHHHEECCCCCCCCHHHHHHHHHHH
ILAIAQAVADYRKQANITGKLILGIDTHALSQPAAISVVEVLVANQISVVVHQNDGFTPT
HHHHHHHHHHHHHHCCCCEEEEEEECHHHCCCCHHHHHHHHHHHCCEEEEEECCCCCCCC
PVVSHAIICANKSPAEGLVDGLIVTPSHNPPQDGGIKYNPPHGGPAEGEITTWVENRANQ
HHHHEEEEECCCCCCCHHHCCEEECCCCCCCCCCCEEECCCCCCCCCCCEEHHHHHHHHH
YLASQLDGVKRVSYAHAVESQYLLEQDLITPYVEDLCNVIDMQAIADAKIRLGIDPLGGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
GIHYWTPIAQHYGIDITVLNEKVDPSFSFMPLDKDGKIRMDCSSPYAMAGLLAHKDNFDL
CCCHHCHHHHHCCCEEEEECCCCCCCEEEEECCCCCCEEEECCCCHHHHHHHEECCCCCE
CLGNDPDFDRHGIVCPGSGLMNPNHFLAVAIDYLLTHRPNWTEQMVIGKTLVSSAMIDKV
EECCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
CAMHNKQMSEVPVGFKWFVEGLANSDFAFGGEESAGAAFLRTDGSTWCTDKDGFILCLLA
HHHHCCHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCEEEECCCCCCHHHHH
AEMLAVTGKTPQQRYDELEVQFGKSFYQRIDSPVSLEDKAKFSTISADAIVADTLAGDTI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEECCCHHHHHHHHHHHH
LQKLTHAPGNGAAIGGIKVVTEKGWFAARPSGTEALFKLYGESFVSLEHLTQLLKDAQQI
HHHHHCCCCCCEEECCEEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAAALR
HHHHCC
>Mature Secondary Structure 
ATHKRAGLIAEQKDLVNIPKLVSLYYCLTPDVNEVSQKVTFGTSGHRGSAVQKSFNEMH
CCCCCCCCCCCCHHHCCHHHHHHHHHCCCCCHHHHHHHEECCCCCCCCHHHHHHHHHHH
ILAIAQAVADYRKQANITGKLILGIDTHALSQPAAISVVEVLVANQISVVVHQNDGFTPT
HHHHHHHHHHHHHHCCCCEEEEEEECHHHCCCCHHHHHHHHHHHCCEEEEEECCCCCCCC
PVVSHAIICANKSPAEGLVDGLIVTPSHNPPQDGGIKYNPPHGGPAEGEITTWVENRANQ
HHHHEEEEECCCCCCCHHHCCEEECCCCCCCCCCCEEECCCCCCCCCCCEEHHHHHHHHH
YLASQLDGVKRVSYAHAVESQYLLEQDLITPYVEDLCNVIDMQAIADAKIRLGIDPLGGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
GIHYWTPIAQHYGIDITVLNEKVDPSFSFMPLDKDGKIRMDCSSPYAMAGLLAHKDNFDL
CCCHHCHHHHHCCCEEEEECCCCCCCEEEEECCCCCCEEEECCCCHHHHHHHEECCCCCE
CLGNDPDFDRHGIVCPGSGLMNPNHFLAVAIDYLLTHRPNWTEQMVIGKTLVSSAMIDKV
EECCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
CAMHNKQMSEVPVGFKWFVEGLANSDFAFGGEESAGAAFLRTDGSTWCTDKDGFILCLLA
HHHHCCHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCEEEECCCCCCHHHHH
AEMLAVTGKTPQQRYDELEVQFGKSFYQRIDSPVSLEDKAKFSTISADAIVADTLAGDTI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHEEECCCHHHHHHHHHHHH
LQKLTHAPGNGAAIGGIKVVTEKGWFAARPSGTEALFKLYGESFVSLEHLTQLLKDAQQI
HHHHHCCCCCCEEECCEEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAAALR
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8083177; 8905232; 9278503; 8011018 [H]