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The map label for this gene is 167624157

Identifier: 167624157

GI number: 167624157

Start: 2708138

End: 2709115

Strand: Reverse

Name: 167624157

Synonym: Shal_2233

Alternate gene names: NA

Gene position: 2709115-2708138 (Counterclockwise)

Preceding gene: 167624158

Following gene: 167624156

Centisome position: 51.83

GC content: 47.03

Gene sequence:

>978_bases
GTGGCTCAGATGAATATGTTGCAAGCCATTAACCAAGCGCTGAGCTCGGAAATGGAATCAGATGAAACAATGACAGTGTT
TGGCGAAGATGTTGGACACTTTGGTGGGGTATTTAGAGCGACTTCGGGTCTACAAGAAAAGTTTGGACGTGACCGCTGTT
TTAATACGCCGTTAACCGAACAAGGTATTGCCGGTTTCGCTAATGGTTTAGCGTCAAATGGTATGACGGCAGTGGCTGAA
ATTCAGTTTGCCGATTATATTTTTCCAGCGATCGATCAGATTGTGAATGAAAGTGCCAAATTTAGATACCGTAGTGGTAA
TGAGTTCGATGTCGGCGGACTAACATTTAGAACCCCATATGGTGGCGGGATTGCAGGTGGCCATTACCACTCGCAATCGC
CAGAAGCTTATTTTACTCAAACACCGGGGCTCAAGGTGGTTGTGCCACGTAATCCTGAGCAAGCCAAAGGCTTATTAATC
GCGTCAATTCGTGATAAAAACCCAGTGATTTTCTTCGAGCCTAAGCGTCTATACCGCGCCTCAGTAGGCGAAGTGCCCGA
GGGCGACTACGTTATTGAATTGGGTAAAGCAGAAGTGGTGAAACAGGGTTCTGATATCACGCTTCTGGGCTGGGGCGCCC
AGATGGAGGTCCTTGAGAAGGCGGCAGAGATGGCGGCCAAAAAAGGAATTTCTTGTGAAATCGTCGATTTAAGAACGCTT
TCTCCATGGGATATCGATACCGTCGCTGCCTCAGTTAAAAAGACCGGTCGTTTACTGATTAACCACGAAGCCCCTTTAAC
GGGTGGTTTCGCAGGCGAAATAGCCGCGACAATCCAAGAAGAGTGCTTCTTGTACCTTGAGTCGCCAATCGCCCGTGTTT
GTGGTCTCGATACACCGTATCCTTTGATCCATGAAAAAGAATATATGCCAGATGCGTTAAAGACGTTTGAAGCGATCAAA
GCTTCGGTTAAATTTTAG

Upstream 100 bases:

>100_bases
TACGCCAACACCAATGCTTAAGAAACAGTTAGCACAGTTGAAAGAACACGTAAAAAAATATCCAGAATCCTATCCAAAAA
GCGCAGGGAGAGTATAAGCC

Downstream 100 bases:

>100_bases
GAGCCAGCCATGATTAAAGATTTTATCCTTCCGGATATCGGCGAAGGCGTTGTCGAGTGTGAGCTGGTCGAATGGTTAGT
ACAAGAGGGTGATACTGTTG

Product: transketolase central region

Products: NA

Alternate protein names: Branched-chain alpha-keto acid dehydrogenase E1 component beta chain; BCKDH E1-beta [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MAQMNMLQAINQALSSEMESDETMTVFGEDVGHFGGVFRATSGLQEKFGRDRCFNTPLTEQGIAGFANGLASNGMTAVAE
IQFADYIFPAIDQIVNESAKFRYRSGNEFDVGGLTFRTPYGGGIAGGHYHSQSPEAYFTQTPGLKVVVPRNPEQAKGLLI
ASIRDKNPVIFFEPKRLYRASVGEVPEGDYVIELGKAEVVKQGSDITLLGWGAQMEVLEKAAEMAAKKGISCEIVDLRTL
SPWDIDTVAASVKKTGRLLINHEAPLTGGFAGEIAATIQEECFLYLESPIARVCGLDTPYPLIHEKEYMPDALKTFEAIK
ASVKF

Sequences:

>Translated_325_residues
MAQMNMLQAINQALSSEMESDETMTVFGEDVGHFGGVFRATSGLQEKFGRDRCFNTPLTEQGIAGFANGLASNGMTAVAE
IQFADYIFPAIDQIVNESAKFRYRSGNEFDVGGLTFRTPYGGGIAGGHYHSQSPEAYFTQTPGLKVVVPRNPEQAKGLLI
ASIRDKNPVIFFEPKRLYRASVGEVPEGDYVIELGKAEVVKQGSDITLLGWGAQMEVLEKAAEMAAKKGISCEIVDLRTL
SPWDIDTVAASVKKTGRLLINHEAPLTGGFAGEIAATIQEECFLYLESPIARVCGLDTPYPLIHEKEYMPDALKTFEAIK
ASVKF
>Mature_324_residues
AQMNMLQAINQALSSEMESDETMTVFGEDVGHFGGVFRATSGLQEKFGRDRCFNTPLTEQGIAGFANGLASNGMTAVAEI
QFADYIFPAIDQIVNESAKFRYRSGNEFDVGGLTFRTPYGGGIAGGHYHSQSPEAYFTQTPGLKVVVPRNPEQAKGLLIA
SIRDKNPVIFFEPKRLYRASVGEVPEGDYVIELGKAEVVKQGSDITLLGWGAQMEVLEKAAEMAAKKGISCEIVDLRTLS
PWDIDTVAASVKKTGRLLINHEAPLTGGFAGEIAATIQEECFLYLESPIARVCGLDTPYPLIHEKEYMPDALKTFEAIKA
SVKF

Specific function: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components:branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltran

COG id: COG0022

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4557353, Length=324, Percent_Identity=59.8765432098765, Blast_Score=422, Evalue=1e-118,
Organism=Homo sapiens, GI34101272, Length=324, Percent_Identity=59.8765432098765, Blast_Score=422, Evalue=1e-118,
Organism=Homo sapiens, GI156564403, Length=329, Percent_Identity=35.8662613981763, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI291084858, Length=329, Percent_Identity=34.3465045592705, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17506935, Length=324, Percent_Identity=59.2592592592593, Blast_Score=385, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17538422, Length=330, Percent_Identity=36.3636363636364, Blast_Score=207, Evalue=6e-54,
Organism=Saccharomyces cerevisiae, GI6319698, Length=324, Percent_Identity=35.8024691358025, Blast_Score=202, Evalue=4e-53,
Organism=Drosophila melanogaster, GI160714828, Length=324, Percent_Identity=57.7160493827161, Blast_Score=395, Evalue=1e-110,
Organism=Drosophila melanogaster, GI160714832, Length=324, Percent_Identity=57.7160493827161, Blast_Score=395, Evalue=1e-110,
Organism=Drosophila melanogaster, GI21358145, Length=303, Percent_Identity=36.963696369637, Blast_Score=206, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24650940, Length=303, Percent_Identity=36.963696369637, Blast_Score=206, Evalue=2e-53,
Organism=Drosophila melanogaster, GI160714826, Length=65, Percent_Identity=52.3076923076923, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24650943, Length=91, Percent_Identity=36.2637362637363, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24650945, Length=91, Percent_Identity=36.2637362637363, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =1.2.4.4 [H]

Molecular weight: Translated: 35393; Mature: 35261

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQMNMLQAINQALSSEMESDETMTVFGEDVGHFGGVFRATSGLQEKFGRDRCFNTPLTE
CCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
QGIAGFANGLASNGMTAVAEIQFADYIFPAIDQIVNESAKFRYRSGNEFDVGGLTFRTPY
HHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHCCCCCEEECCCCEECCCCEEEECCC
GGGIAGGHYHSQSPEAYFTQTPGLKVVVPRNPEQAKGLLIASIRDKNPVIFFEPKRLYRA
CCCCCCCCCCCCCCCEEEECCCCEEEEECCCCHHHCCEEEEEECCCCCEEEECCHHHHHH
SVGEVPEGDYVIELGKAEVVKQGSDITLLGWGAQMEVLEKAAEMAAKKGISCEIVDLRTL
HCCCCCCCCEEEEECCHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEEEEECC
SPWDIDTVAASVKKTGRLLINHEAPLTGGFAGEIAATIQEECFLYLESPIARVCGLDTPY
CCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PLIHEKEYMPDALKTFEAIKASVKF
CCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AQMNMLQAINQALSSEMESDETMTVFGEDVGHFGGVFRATSGLQEKFGRDRCFNTPLTE
CHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
QGIAGFANGLASNGMTAVAEIQFADYIFPAIDQIVNESAKFRYRSGNEFDVGGLTFRTPY
HHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHCCCCCEEECCCCEECCCCEEEECCC
GGGIAGGHYHSQSPEAYFTQTPGLKVVVPRNPEQAKGLLIASIRDKNPVIFFEPKRLYRA
CCCCCCCCCCCCCCCEEEECCCCEEEEECCCCHHHCCEEEEEECCCCCEEEECCHHHHHH
SVGEVPEGDYVIELGKAEVVKQGSDITLLGWGAQMEVLEKAAEMAAKKGISCEIVDLRTL
HCCCCCCCCEEEEECCHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEEEEECC
SPWDIDTVAASVKKTGRLLINHEAPLTGGFAGEIAATIQEECFLYLESPIARVCGLDTPY
CCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PLIHEKEYMPDALKTFEAIKASVKF
CCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA