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The map label for this gene is dmsA [H]

Identifier: 167624077

GI number: 167624077

Start: 2596963

End: 2599602

Strand: Reverse

Name: dmsA [H]

Synonym: Shal_2153

Alternate gene names: 167624077

Gene position: 2599602-2596963 (Counterclockwise)

Preceding gene: 167624078

Following gene: 167624076

Centisome position: 49.73

GC content: 45.15

Gene sequence:

>2640_bases
ATGACATTAACTAGACGTGACTTCATTAAATCTGCACTCGCAAGCACCGTTGCTGCACAAGGACTTACCTTGTTTCCTGC
TGGAAAAGTATTTGCAGCCGACACTCAAACTATTCCCCATGCCAGCCATTATGGTCCCTTTAATGCTATCGTCAAAGAGG
GAGTGTTGATCGGCGTTCAGCCATTGACAGATATTGACCCCTTCCCGACAAAGATGTTGTTAGAAGGGATCCTAAGCCGA
ACCTACAGCGACACTAGGGTAAAATACCCAATGGTGCGTAAATCCTATTTAGAGAACCCTTTAGGCGATCATAAGCCACA
CCTTAGAGGTAAAGAGCCTTTTGTCCGCGTAGACTGGAATACGGCTATGGCTATGGTCAGTACCGCTATTGCCAATACGA
TAGCCAAGCATGGTAACCAAGCTATTTTCAGCTCATCATACGGCGGATGGTCCCATGCAGGTTTAATGCGTCCCCAGACA
TTACAAGGCCGCTTTTTCAATTTAGTTGGTGGACAGAGTGCTTGTAGCGGTGATTACAGCGCAGGTGCATCTGAAGTGAT
ATTACCTCATATCATAGGCGATATGGAGGTCTACTCCCCTCAAACTGCATGGCAAGTAATTGAAGACAATACAGAATTGA
TGTTATTGGTTGGCTGTGATCCCTATAAAACCAATAGAATTGAGTTTAGGGTAGCGGATCATGCTATGCATAAGCACTGG
CAAGCCTTTGCAAAAAAAGGGATTAAGTTTGTTTCTATAAACCCTCAACAAACCCAAACAGACAAAGCCATGGCTAGCGA
GATGATCAATATTCGCCCCAACACCGATGTCGCACTGTTTACCGCTATGTCTTACCATATATACAAATCTGATTTGTATG
ATAAAGCGTATCTAGATAAATACACCGTTGGCTTTAAACAATACCTTGATTACCTTAAAGGCACTGCTGACAACACAGCT
AAAACCCCCGAGTGGGCCGAGGCGATAACCGGTGTGAGTGCTAAGCAAATTCGTGAATTGGCTGAAGAGGTAGTAAAGAA
ACGCACGCAAATTTGTGCCGGATGGTCACTACAGCGAGCACAACATGGAGAGATGATCCACTGGGCTATTATCAACTTTG
CGGCTATGGCGGGCAAAATTGGTAAACCGGGTGAAGGCGCAGGTTTTAGCTGGCATTATGGTAATGGCGGCATGCCGCAA
TCAGGTAAAAAGATGCCTGCAGGTTTATCGCAAGGCAGAAACCCAATAACCGCGCGCTGCCCTGTGGTATTGATCTCTGA
AATGTTGAATAACCCTGGCAGCAACTACACTCGTAATGGCCAAACCCTGACATTTCCAGACGCTAAGCTAATCTATAATG
CGGGTAATAATTTACTGTCCCACCAGCAAAATACTAACGAATTAATCCAAGCCCTAAATAACAATGTTGAAACCATCATT
AATCAAGATCCTTGGTGGTGTGCCTCCTCAGTTTATGCCGATATTGTTCTGCCAAGCACAACAACACTTGAACGCAATGA
TATTAGCTCTGGCGGTACCTATTCCAACAACAAGATCTACGCCATGAAGCAAGTGCTCGAGCCTGTAGGTGAAAGTTGGA
ATGATTATGAAATCTTCTCTGCATTGGCAAAAATATTTAATGTTCAGCAGCAATTCACTCAAGGCAAAACATTTATGCAG
CACCTTAAGGATGCGTATGCTGCGTCTGATGCGAGCGATAGCTTTGACAGCTTCTGGGATAAAGGTGTCACTCACCTCAG
TACACCGAAAGCGGCGACTGACTGGGTTCGTCACCGTGATTTTTATCTAGATCCAATAAAACATCCACTGCACACACCAT
CAGGTAAAATTGAGCTTTATAGTGAGCAGATTAAGTCATACCAGTTGCCTGACTGCCCGCCTATGCCTGAATGGATCCCT
CCTGCCGAATGGCTTGGCAATGCGAAACCCGAGCAAGTCCATGTTTTAAGCCCTCACCCATGGATGCGCTTACATTCGCA
GATGGCCAATGCTGACGTTAACAGCTATGAGTCCGTGGATGGCCGCCAATTTGCGTTAATTAATAAAGATGACGCTGCAC
AGCGTGGCATTAAAGGTGGAGATTTGATTGAGGTTTACAATGACCGCGGGGCGCTATTAGCGGGGGCGAAGATCGCCGAC
AATGTGATGCCAGGTGTTATTTATATCCATGAAGGGGCTTGGCTTCAATTAGATAACAAGGGCCGCTGTAATTCAGGCTC
AATTAACATGTTAACTTCTGCTCGACCATCAAGCGGATTAAGCCAAGGCACGAGTGCAAATACCTGCTTGGCGTCCTTTA
AAAAGTGTTTAGATCCAGAGTCACCGAATAAAGCTTATCAGCCTCCCAAAATTGAAATCCCTAAGACCCCGTTTGATATA
AGTAGTTTGGGACTGGCCGCGGCCCTGAAATCGATAAAGTCTGTCAAACAGCAAACTCAGAGTAAAGGTGAAAAGATCTT
CTATCATGCATGCACTATGTGCCATTCGGCGCCAAACCCTGCAGATCATAGTTATAAACAGTGGCAAGGTATTACTCGTA
GTATGTTCCCAAGAGCTGGATTAAACCCAGATGAACAGGCTGAGGTACTTAAGTTTTTGAAACAGCATGCTAAACAGTAA

Upstream 100 bases:

>100_bases
GACGATATTTAATGCTGCAGCACTTGTTAAATCGACTAATATAAGCCATAACGAATAGCATATTCTTCTACCACCTCAAT
ATATCGAGAGCCTGACTGAT

Downstream 100 bases:

>100_bases
ATCTGTATTGCCTATGCCCTATGCTTGTATTTGGTTTAATTTAATTAAGAACAAAGACAGCAATTAGCTAAAATGGATGT
ATTAGCCCTCATTACTCATT

Product: molybdopterin oxidoreductase

Products: Biotin [C]

Alternate protein names: DMSO reductase; DMSOR [H]

Number of amino acids: Translated: 879; Mature: 878

Protein sequence:

>879_residues
MTLTRRDFIKSALASTVAAQGLTLFPAGKVFAADTQTIPHASHYGPFNAIVKEGVLIGVQPLTDIDPFPTKMLLEGILSR
TYSDTRVKYPMVRKSYLENPLGDHKPHLRGKEPFVRVDWNTAMAMVSTAIANTIAKHGNQAIFSSSYGGWSHAGLMRPQT
LQGRFFNLVGGQSACSGDYSAGASEVILPHIIGDMEVYSPQTAWQVIEDNTELMLLVGCDPYKTNRIEFRVADHAMHKHW
QAFAKKGIKFVSINPQQTQTDKAMASEMINIRPNTDVALFTAMSYHIYKSDLYDKAYLDKYTVGFKQYLDYLKGTADNTA
KTPEWAEAITGVSAKQIRELAEEVVKKRTQICAGWSLQRAQHGEMIHWAIINFAAMAGKIGKPGEGAGFSWHYGNGGMPQ
SGKKMPAGLSQGRNPITARCPVVLISEMLNNPGSNYTRNGQTLTFPDAKLIYNAGNNLLSHQQNTNELIQALNNNVETII
NQDPWWCASSVYADIVLPSTTTLERNDISSGGTYSNNKIYAMKQVLEPVGESWNDYEIFSALAKIFNVQQQFTQGKTFMQ
HLKDAYAASDASDSFDSFWDKGVTHLSTPKAATDWVRHRDFYLDPIKHPLHTPSGKIELYSEQIKSYQLPDCPPMPEWIP
PAEWLGNAKPEQVHVLSPHPWMRLHSQMANADVNSYESVDGRQFALINKDDAAQRGIKGGDLIEVYNDRGALLAGAKIAD
NVMPGVIYIHEGAWLQLDNKGRCNSGSINMLTSARPSSGLSQGTSANTCLASFKKCLDPESPNKAYQPPKIEIPKTPFDI
SSLGLAAALKSIKSVKQQTQSKGEKIFYHACTMCHSAPNPADHSYKQWQGITRSMFPRAGLNPDEQAEVLKFLKQHAKQ

Sequences:

>Translated_879_residues
MTLTRRDFIKSALASTVAAQGLTLFPAGKVFAADTQTIPHASHYGPFNAIVKEGVLIGVQPLTDIDPFPTKMLLEGILSR
TYSDTRVKYPMVRKSYLENPLGDHKPHLRGKEPFVRVDWNTAMAMVSTAIANTIAKHGNQAIFSSSYGGWSHAGLMRPQT
LQGRFFNLVGGQSACSGDYSAGASEVILPHIIGDMEVYSPQTAWQVIEDNTELMLLVGCDPYKTNRIEFRVADHAMHKHW
QAFAKKGIKFVSINPQQTQTDKAMASEMINIRPNTDVALFTAMSYHIYKSDLYDKAYLDKYTVGFKQYLDYLKGTADNTA
KTPEWAEAITGVSAKQIRELAEEVVKKRTQICAGWSLQRAQHGEMIHWAIINFAAMAGKIGKPGEGAGFSWHYGNGGMPQ
SGKKMPAGLSQGRNPITARCPVVLISEMLNNPGSNYTRNGQTLTFPDAKLIYNAGNNLLSHQQNTNELIQALNNNVETII
NQDPWWCASSVYADIVLPSTTTLERNDISSGGTYSNNKIYAMKQVLEPVGESWNDYEIFSALAKIFNVQQQFTQGKTFMQ
HLKDAYAASDASDSFDSFWDKGVTHLSTPKAATDWVRHRDFYLDPIKHPLHTPSGKIELYSEQIKSYQLPDCPPMPEWIP
PAEWLGNAKPEQVHVLSPHPWMRLHSQMANADVNSYESVDGRQFALINKDDAAQRGIKGGDLIEVYNDRGALLAGAKIAD
NVMPGVIYIHEGAWLQLDNKGRCNSGSINMLTSARPSSGLSQGTSANTCLASFKKCLDPESPNKAYQPPKIEIPKTPFDI
SSLGLAAALKSIKSVKQQTQSKGEKIFYHACTMCHSAPNPADHSYKQWQGITRSMFPRAGLNPDEQAEVLKFLKQHAKQ
>Mature_878_residues
TLTRRDFIKSALASTVAAQGLTLFPAGKVFAADTQTIPHASHYGPFNAIVKEGVLIGVQPLTDIDPFPTKMLLEGILSRT
YSDTRVKYPMVRKSYLENPLGDHKPHLRGKEPFVRVDWNTAMAMVSTAIANTIAKHGNQAIFSSSYGGWSHAGLMRPQTL
QGRFFNLVGGQSACSGDYSAGASEVILPHIIGDMEVYSPQTAWQVIEDNTELMLLVGCDPYKTNRIEFRVADHAMHKHWQ
AFAKKGIKFVSINPQQTQTDKAMASEMINIRPNTDVALFTAMSYHIYKSDLYDKAYLDKYTVGFKQYLDYLKGTADNTAK
TPEWAEAITGVSAKQIRELAEEVVKKRTQICAGWSLQRAQHGEMIHWAIINFAAMAGKIGKPGEGAGFSWHYGNGGMPQS
GKKMPAGLSQGRNPITARCPVVLISEMLNNPGSNYTRNGQTLTFPDAKLIYNAGNNLLSHQQNTNELIQALNNNVETIIN
QDPWWCASSVYADIVLPSTTTLERNDISSGGTYSNNKIYAMKQVLEPVGESWNDYEIFSALAKIFNVQQQFTQGKTFMQH
LKDAYAASDASDSFDSFWDKGVTHLSTPKAATDWVRHRDFYLDPIKHPLHTPSGKIELYSEQIKSYQLPDCPPMPEWIPP
AEWLGNAKPEQVHVLSPHPWMRLHSQMANADVNSYESVDGRQFALINKDDAAQRGIKGGDLIEVYNDRGALLAGAKIADN
VMPGVIYIHEGAWLQLDNKGRCNSGSINMLTSARPSSGLSQGTSANTCLASFKKCLDPESPNKAYQPPKIEIPKTPFDIS
SLGLAAALKSIKSVKQQTQSKGEKIFYHACTMCHSAPNPADHSYKQWQGITRSMFPRAGLNPDEQAEVLKFLKQHAKQ

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081994, Length=819, Percent_Identity=37.4847374847375, Blast_Score=535, Evalue=1e-153,
Organism=Escherichia coli, GI145693196, Length=741, Percent_Identity=38.191632928475, Blast_Score=523, Evalue=1e-149,
Organism=Escherichia coli, GI1787231, Length=781, Percent_Identity=35.8514724711908, Blast_Score=459, Evalue=1e-130,
Organism=Escherichia coli, GI87081797, Length=739, Percent_Identity=31.1231393775372, Blast_Score=278, Evalue=2e-75,
Organism=Escherichia coli, GI1787870, Length=748, Percent_Identity=29.0106951871658, Blast_Score=245, Evalue=9e-66,
Organism=Escherichia coli, GI171474008, Length=744, Percent_Identity=28.494623655914, Blast_Score=234, Evalue=2e-62,
Organism=Escherichia coli, GI3868721, Length=677, Percent_Identity=22.3042836041359, Blast_Score=107, Evalue=4e-24,
Organism=Escherichia coli, GI1787778, Length=181, Percent_Identity=30.3867403314917, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.7.2.3 [C]

Molecular weight: Translated: 97331; Mature: 97200

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTRRDFIKSALASTVAAQGLTLFPAGKVFAADTQTIPHASHYGPFNAIVKEGVLIGVQ
CCCCHHHHHHHHHHHHHHHCCCEEECCCCEEECCCCCCCCCCCCCCHHHHHHCCEEEEEC
PLTDIDPFPTKMLLEGILSRTYSDTRVKYPMVRKSYLENPLGDHKPHLRGKEPFVRVDWN
CCCCCCCCCHHHHHHHHHHHCCCCCEEECHHHHHHHHCCCCCCCCCCCCCCCCEEEEECH
TAMAMVSTAIANTIAKHGNQAIFSSSYGGWSHAGLMRPQTLQGRFFNLVGGQSACSGDYS
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHCCCHHEECCCCCCCCCCCC
AGASEVILPHIIGDMEVYSPQTAWQVIEDNTELMLLVGCDPYKTNRIEFRVADHAMHKHW
CCCCHHHHHHHHCCCHHCCCHHHHHHEECCCCEEEEECCCCCCCCEEEEEEHHHHHHHHH
QAFAKKGIKFVSINPQQTQTDKAMASEMINIRPNTDVALFTAMSYHIYKSDLYDKAYLDK
HHHHHCCCEEEEECCCHHHHHHHHHHHHEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
YTVGFKQYLDYLKGTADNTAKTPEWAEAITGVSAKQIRELAEEVVKKRTQICAGWSLQRA
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHH
QHGEMIHWAIINFAAMAGKIGKPGEGAGFSWHYGNGGMPQSGKKMPAGLSQGRNPITARC
CCCCEEHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHCCCCCCCCCC
PVVLISEMLNNPGSNYTRNGQTLTFPDAKLIYNAGNNLLSHQQNTNELIQALNNNVETII
HHHHHHHHHCCCCCCCCCCCCEEECCCCEEEEECCCHHHHCCCCHHHHHHHHCCCHHHHC
NQDPWWCASSVYADIVLPSTTTLERNDISSGGTYSNNKIYAMKQVLEPVGESWNDYEIFS
CCCCCHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCHHHHHH
ALAKIFNVQQQFTQGKTFMQHLKDAYAASDASDSFDSFWDKGVTHLSTPKAATDWVRHRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHCC
FYLDPIKHPLHTPSGKIELYSEQIKSYQLPDCPPMPEWIPPAEWLGNAKPEQVHVLSPHP
CEECCCCCCCCCCCCCEEEEHHHHHCCCCCCCCCCCCCCCCHHHHCCCCCCEEEEECCCH
WMRLHSQMANADVNSYESVDGRQFALINKDDAAQRGIKGGDLIEVYNDRGALLAGAKIAD
HHHHHHHHHCCCCCCCCCCCCCEEEEECCCHHHHCCCCCCCEEEEECCCCCEEECCHHHH
NVMPGVIYIHEGAWLQLDNKGRCNSGSINMLTSARPSSGLSQGTSANTCLASFKKCLDPE
CCCCCEEEEECCCEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCC
SPNKAYQPPKIEIPKTPFDISSLGLAAALKSIKSVKQQTQSKGEKIFYHACTMCHSAPNP
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHCCCCC
ADHSYKQWQGITRSMFPRAGLNPDEQAEVLKFLKQHAKQ
CCCCHHHHHCHHHHHCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLTRRDFIKSALASTVAAQGLTLFPAGKVFAADTQTIPHASHYGPFNAIVKEGVLIGVQ
CCCHHHHHHHHHHHHHHHCCCEEECCCCEEECCCCCCCCCCCCCCHHHHHHCCEEEEEC
PLTDIDPFPTKMLLEGILSRTYSDTRVKYPMVRKSYLENPLGDHKPHLRGKEPFVRVDWN
CCCCCCCCCHHHHHHHHHHHCCCCCEEECHHHHHHHHCCCCCCCCCCCCCCCCEEEEECH
TAMAMVSTAIANTIAKHGNQAIFSSSYGGWSHAGLMRPQTLQGRFFNLVGGQSACSGDYS
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHCCCHHEECCCCCCCCCCCC
AGASEVILPHIIGDMEVYSPQTAWQVIEDNTELMLLVGCDPYKTNRIEFRVADHAMHKHW
CCCCHHHHHHHHCCCHHCCCHHHHHHEECCCCEEEEECCCCCCCCEEEEEEHHHHHHHHH
QAFAKKGIKFVSINPQQTQTDKAMASEMINIRPNTDVALFTAMSYHIYKSDLYDKAYLDK
HHHHHCCCEEEEECCCHHHHHHHHHHHHEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
YTVGFKQYLDYLKGTADNTAKTPEWAEAITGVSAKQIRELAEEVVKKRTQICAGWSLQRA
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHH
QHGEMIHWAIINFAAMAGKIGKPGEGAGFSWHYGNGGMPQSGKKMPAGLSQGRNPITARC
CCCCEEHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHCCCCCCCCCC
PVVLISEMLNNPGSNYTRNGQTLTFPDAKLIYNAGNNLLSHQQNTNELIQALNNNVETII
HHHHHHHHHCCCCCCCCCCCCEEECCCCEEEEECCCHHHHCCCCHHHHHHHHCCCHHHHC
NQDPWWCASSVYADIVLPSTTTLERNDISSGGTYSNNKIYAMKQVLEPVGESWNDYEIFS
CCCCCHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCHHHHHH
ALAKIFNVQQQFTQGKTFMQHLKDAYAASDASDSFDSFWDKGVTHLSTPKAATDWVRHRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHCC
FYLDPIKHPLHTPSGKIELYSEQIKSYQLPDCPPMPEWIPPAEWLGNAKPEQVHVLSPHP
CEECCCCCCCCCCCCCEEEEHHHHHCCCCCCCCCCCCCCCCHHHHCCCCCCEEEEECCCH
WMRLHSQMANADVNSYESVDGRQFALINKDDAAQRGIKGGDLIEVYNDRGALLAGAKIAD
HHHHHHHHHCCCCCCCCCCCCCEEEEECCCHHHHCCCCCCCEEEEECCCCCEEECCHHHH
NVMPGVIYIHEGAWLQLDNKGRCNSGSINMLTSARPSSGLSQGTSANTCLASFKKCLDPE
CCCCCEEEEECCCEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCC
SPNKAYQPPKIEIPKTPFDISSLGLAAALKSIKSVKQQTQSKGEKIFYHACTMCHSAPNP
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHCCCCC
ADHSYKQWQGITRSMFPRAGLNPDEQAEVLKFLKQHAKQ
CCCCHHHHHCHHHHHCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Spontaneous Oxidation Product Of Biotin, D-Biotin D-Sulfoxide (Bso Or Bds) [C]

Specific reaction: Reduces A Spontaneous Oxidation Product Of Biotin, D-Biotin D-Sulfoxide (Bso Or Bds), Back To Biotin. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8645727; 8534974; 7625833; 8658134 [H]