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The map label for this gene is fadH [H]

Identifier: 167623956

GI number: 167623956

Start: 2447138

End: 2449153

Strand: Direct

Name: fadH [H]

Synonym: Shal_2030

Alternate gene names: 167623956

Gene position: 2447138-2449153 (Clockwise)

Preceding gene: 167623953

Following gene: 167623958

Centisome position: 46.82

GC content: 48.51

Gene sequence:

>2016_bases
ATGTCGTTTCCGCATTTATTAGAACCCTTAGATCTGGGGTTCACCCAGTTAAAAAACCGTGTGTTGATGGGTTCAATGCA
CACAGGTTTAGAAGAAGAAAAGGGCGGTTTTGAGAAACTGGCAGTGTTTTATAAGGAACGTGCGCTAGGTGGTGTTGGGT
TAATCGTTACCGGAGGGATCTCGCCTAACCTACGCGGCCGTCTTGCCCCTAACGCTTGCCAGTTAAGCTTTCCTTGGCAA
GTCAAAAAACACACCAAAGTGACCCAAGCGGTTCATGAGGCTGGCGGCAAAATTTGTATGCAGCTATTGCACGCAGGACG
CTACGGTTATCATCCGTTCTCAAGTGCGCCGAGTAAGATTAAATCGCCTATCACCCCGTTTACTCCGTCTGCTATGTCAA
CAAGACAGGTCTCCTGTACGATTAAAGACTATGTCACCAGCGCAGCATTAGCCAAAAAAGCGGGCTATGACGGCGTGGAA
GTGATGGGCAGTGAAGGTTACCTGATTAATCAGTTTGTTAGCTCTCGTACCAACAAGCGAACCGATAAGTGGGGCGGCGG
CTTTGAAAACCGTGCCCAATTCCCGATAGAGATCGTTAAACAAATTCGCGCTAAGGTTGGCTCTGATTTTATTATCATCT
TTAGATTGTCGATGTTAGATCTTGTTGATAATGGCTCCACTTGGGAAGAGGTGGTACAACTCGCTAAGTGGCTAGAGCAA
GCAGGCGTCACCATCATCAATACAGGGATCGGTTGGCATGAAGCGCGCGTTCCGACCATAGCCACCAGTGTGCCTCGCGG
CGCATTTTCTTGGGTGACAGAGCGTTTGATGAAAGAGATGTCTATCCCGCTGATAGCGACCAACCGCATCAACACGCCTG
AAGTCGCTGAGCATATCATTTCATCCGGCCAAGCGGATATGGTATCGATGGCGCGTCCTTTCCTGGCCGATCCTGATTTC
GTCAACAAAGCGGCGGCGAATACACCTGAACTAATCAATACTTGTATTGGCTGTAATCAGGCTTGTCTTGATCATACCTT
CGCTCTGAAGCGCGCAACCTGTCTTGTTAACCCTAGAGCCTGTTATGAAACTGAGCTGAACTTTACGCCAGCTCAGCATA
AGAAGCGCATTGCAGTGATGGGCGCCGGACCTGCCGGAATGGCATTTTCAATTTATGCGGCGAGGCGCGGCCATGATGTG
GTGCTGTTTGAGGCTAAATCAGAGGTGGGCGGCCAGTTTAATCTTGCACGTAAAATACCAGGCAAAGAGGAGTTTAATGA
AACCATTCGTTACTTCCTTAATCAAATAAAGCTGCACAAGGTGGAACTACGTTTAAACACTCGTCTCGATGCCAGTGTCG
TCCGAGATGAGAAGTTCGATGAAATCGTTATATCGTCAGGTGTAATGCCTAGACCGATTGAGCTACCTGGTTTTGATAAC
CCTAAAGTGGTCGACTACCAAAAAGTACTCAATGGTGAAGTGCAAATAGGCCTGAAGGTCGCGCTTATCGGTGCCGGTGG
TATTGGTTTTGATATGGCGCATTTCCTTTGTGAGTCAGAGTCTTCGACGCTGGATCTCAATCGCTGGTTAAAGCAGTGGG
GGATAGATAAAGACTATAAAGAACCGGGCGGTTTGACGGAACCTGTGCCAGAAGGTAAGCATAGACAAGTGTACTTATTG
CAACGTAAGGCCACCAAGATGGGTAAGGGGCTGGGTAAAACTACGGGGTGGATCCATCGCTCAGTACTGAAGCAACATCA
AGTGACAATGAAAACAGGCGTGAGCTACGAGAAGTTTGACCAGCAAGGTTTGCATATCAAGGTAGAGGGTAAAGCCGAAG
TGCTAGATGTCGATAATGTCATCTTGTGCGCAGGGCAAGTATCAAATACTGAGCTTGTGGATGAGATGAAGTCTACTGGT
ATACCCGTGCACCTAATCGGTGGCGTTGATGTTGCTGCAGAGCTAGATGCCAAGCGCGCAATTCGCCAAGGTGCGGAGTT
AGCTATCGCGCTGTAA

Upstream 100 bases:

>100_bases
GGAAAATTCAATTGTAAAGGAATCTATTAGCAGGCTTATTGAGCTTATTGTTTACACAGGGTATGCTGGATTGAATCACT
TGTTTAAAAAGGATGTTTGA

Downstream 100 bases:

>100_bases
ATTAACGAATGCCGCTACTCTTTTGATATAGCAGGTAAGCATTTAAAAAAACCTGATTATGCAGATGCATAAACAGGTTT
TTTTGTGTTACAAAGGCACT

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MSFPHLLEPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAVFYKERALGGVGLIVTGGISPNLRGRLAPNACQLSFPWQ
VKKHTKVTQAVHEAGGKICMQLLHAGRYGYHPFSSAPSKIKSPITPFTPSAMSTRQVSCTIKDYVTSAALAKKAGYDGVE
VMGSEGYLINQFVSSRTNKRTDKWGGGFENRAQFPIEIVKQIRAKVGSDFIIIFRLSMLDLVDNGSTWEEVVQLAKWLEQ
AGVTIINTGIGWHEARVPTIATSVPRGAFSWVTERLMKEMSIPLIATNRINTPEVAEHIISSGQADMVSMARPFLADPDF
VNKAAANTPELINTCIGCNQACLDHTFALKRATCLVNPRACYETELNFTPAQHKKRIAVMGAGPAGMAFSIYAARRGHDV
VLFEAKSEVGGQFNLARKIPGKEEFNETIRYFLNQIKLHKVELRLNTRLDASVVRDEKFDEIVISSGVMPRPIELPGFDN
PKVVDYQKVLNGEVQIGLKVALIGAGGIGFDMAHFLCESESSTLDLNRWLKQWGIDKDYKEPGGLTEPVPEGKHRQVYLL
QRKATKMGKGLGKTTGWIHRSVLKQHQVTMKTGVSYEKFDQQGLHIKVEGKAEVLDVDNVILCAGQVSNTELVDEMKSTG
IPVHLIGGVDVAAELDAKRAIRQGAELAIAL

Sequences:

>Translated_671_residues
MSFPHLLEPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAVFYKERALGGVGLIVTGGISPNLRGRLAPNACQLSFPWQ
VKKHTKVTQAVHEAGGKICMQLLHAGRYGYHPFSSAPSKIKSPITPFTPSAMSTRQVSCTIKDYVTSAALAKKAGYDGVE
VMGSEGYLINQFVSSRTNKRTDKWGGGFENRAQFPIEIVKQIRAKVGSDFIIIFRLSMLDLVDNGSTWEEVVQLAKWLEQ
AGVTIINTGIGWHEARVPTIATSVPRGAFSWVTERLMKEMSIPLIATNRINTPEVAEHIISSGQADMVSMARPFLADPDF
VNKAAANTPELINTCIGCNQACLDHTFALKRATCLVNPRACYETELNFTPAQHKKRIAVMGAGPAGMAFSIYAARRGHDV
VLFEAKSEVGGQFNLARKIPGKEEFNETIRYFLNQIKLHKVELRLNTRLDASVVRDEKFDEIVISSGVMPRPIELPGFDN
PKVVDYQKVLNGEVQIGLKVALIGAGGIGFDMAHFLCESESSTLDLNRWLKQWGIDKDYKEPGGLTEPVPEGKHRQVYLL
QRKATKMGKGLGKTTGWIHRSVLKQHQVTMKTGVSYEKFDQQGLHIKVEGKAEVLDVDNVILCAGQVSNTELVDEMKSTG
IPVHLIGGVDVAAELDAKRAIRQGAELAIAL
>Mature_670_residues
SFPHLLEPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAVFYKERALGGVGLIVTGGISPNLRGRLAPNACQLSFPWQV
KKHTKVTQAVHEAGGKICMQLLHAGRYGYHPFSSAPSKIKSPITPFTPSAMSTRQVSCTIKDYVTSAALAKKAGYDGVEV
MGSEGYLINQFVSSRTNKRTDKWGGGFENRAQFPIEIVKQIRAKVGSDFIIIFRLSMLDLVDNGSTWEEVVQLAKWLEQA
GVTIINTGIGWHEARVPTIATSVPRGAFSWVTERLMKEMSIPLIATNRINTPEVAEHIISSGQADMVSMARPFLADPDFV
NKAAANTPELINTCIGCNQACLDHTFALKRATCLVNPRACYETELNFTPAQHKKRIAVMGAGPAGMAFSIYAARRGHDVV
LFEAKSEVGGQFNLARKIPGKEEFNETIRYFLNQIKLHKVELRLNTRLDASVVRDEKFDEIVISSGVMPRPIELPGFDNP
KVVDYQKVLNGEVQIGLKVALIGAGGIGFDMAHFLCESESSTLDLNRWLKQWGIDKDYKEPGGLTEPVPEGKHRQVYLLQ
RKATKMGKGLGKTTGWIHRSVLKQHQVTMKTGVSYEKFDQQGLHIKVEGKAEVLDVDNVILCAGQVSNTELVDEMKSTGI
PVHLIGGVDVAAELDAKRAIRQGAELAIAL

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=677, Percent_Identity=54.9483013293944, Blast_Score=770, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=349, Percent_Identity=28.6532951289398, Blast_Score=111, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17540738, Length=307, Percent_Identity=27.3615635179153, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17559802, Length=256, Percent_Identity=27.34375, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17559804, Length=250, Percent_Identity=28, Blast_Score=93, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17564188, Length=248, Percent_Identity=28.2258064516129, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17565138, Length=303, Percent_Identity=24.4224422442244, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI72001454, Length=255, Percent_Identity=29.0196078431373, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17566914, Length=347, Percent_Identity=23.9193083573487, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6325086, Length=234, Percent_Identity=30.3418803418803, Blast_Score=88, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6321973, Length=353, Percent_Identity=24.6458923512748, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 73792; Mature: 73661

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFPHLLEPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAVFYKERALGGVGLIVTGGI
CCCCCCCCHHHCCHHHHHCCEEECHHHCCCCHHCCCHHHHHHHHHHHCCCCEEEEEECCC
SPNLRGRLAPNACQLSFPWQVKKHTKVTQAVHEAGGKICMQLLHAGRYGYHPFSSAPSKI
CCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
KSPITPFTPSAMSTRQVSCTIKDYVTSAALAKKAGYDGVEVMGSEGYLINQFVSSRTNKR
CCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCEEEECCCCEEHHHHHHHCCCCC
TDKWGGGFENRAQFPIEIVKQIRAKVGSDFIIIFRLSMLDLVDNGSTWEEVVQLAKWLEQ
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHCCCCCHHHHHHHHHHHHH
AGVTIINTGIGWHEARVPTIATSVPRGAFSWVTERLMKEMSIPLIATNRINTPEVAEHII
CCCEEEECCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHH
SSGQADMVSMARPFLADPDFVNKAAANTPELINTCIGCNQACLDHTFALKRATCLVNPRA
CCCCHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHEEECCCH
CYETELNFTPAQHKKRIAVMGAGPAGMAFSIYAARRGHDVVLFEAKSEVGGQFNLARKIP
HEECCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCEEEEEECCCCCCCCEEEHHCCC
GKEEFNETIRYFLNQIKLHKVELRLNTRLDASVVRDEKFDEIVISSGVMPRPIELPGFDN
CHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHCCCCHHHHHHCCCCCCCCCCCCCCCC
PKVVDYQKVLNGEVQIGLKVALIGAGGIGFDMAHFLCESESSTLDLNRWLKQWGIDKDYK
CCEEEHHHHHCCCEEEEEEEEEEECCCCHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCCC
EPGGLTEPVPEGKHRQVYLLQRKATKMGKGLGKTTGWIHRSVLKQHQVTMKTGVSYEKFD
CCCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHC
QQGLHIKVEGKAEVLDVDNVILCAGQVSNTELVDEMKSTGIPVHLIGGVDVAAELDAKRA
CCCCEEEECCCEEEEECCCEEEECCCCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHH
IRQGAELAIAL
HHCCCCEEEEC
>Mature Secondary Structure 
SFPHLLEPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAVFYKERALGGVGLIVTGGI
CCCCCCCHHHCCHHHHHCCEEECHHHCCCCHHCCCHHHHHHHHHHHCCCCEEEEEECCC
SPNLRGRLAPNACQLSFPWQVKKHTKVTQAVHEAGGKICMQLLHAGRYGYHPFSSAPSKI
CCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
KSPITPFTPSAMSTRQVSCTIKDYVTSAALAKKAGYDGVEVMGSEGYLINQFVSSRTNKR
CCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCEEEECCCCEEHHHHHHHCCCCC
TDKWGGGFENRAQFPIEIVKQIRAKVGSDFIIIFRLSMLDLVDNGSTWEEVVQLAKWLEQ
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHCCCCCHHHHHHHHHHHHH
AGVTIINTGIGWHEARVPTIATSVPRGAFSWVTERLMKEMSIPLIATNRINTPEVAEHII
CCCEEEECCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHH
SSGQADMVSMARPFLADPDFVNKAAANTPELINTCIGCNQACLDHTFALKRATCLVNPRA
CCCCHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHEEECCCH
CYETELNFTPAQHKKRIAVMGAGPAGMAFSIYAARRGHDVVLFEAKSEVGGQFNLARKIP
HEECCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCEEEEEECCCCCCCCEEEHHCCC
GKEEFNETIRYFLNQIKLHKVELRLNTRLDASVVRDEKFDEIVISSGVMPRPIELPGFDN
CHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHCCCCHHHHHHCCCCCCCCCCCCCCCC
PKVVDYQKVLNGEVQIGLKVALIGAGGIGFDMAHFLCESESSTLDLNRWLKQWGIDKDYK
CCEEEHHHHHCCCEEEEEEEEEEECCCCHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCCC
EPGGLTEPVPEGKHRQVYLLQRKATKMGKGLGKTTGWIHRSVLKQHQVTMKTGVSYEKFD
CCCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHC
QQGLHIKVEGKAEVLDVDNVILCAGQVSNTELVDEMKSTGIPVHLIGGVDVAAELDAKRA
CCCCEEEECCCEEEEECCCEEEECCCCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHH
IRQGAELAIAL
HHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]