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The map label for this gene is phbC [H]

Identifier: 167623916

GI number: 167623916

Start: 2395051

End: 2396808

Strand: Direct

Name: phbC [H]

Synonym: Shal_1987

Alternate gene names: 167623916

Gene position: 2395051-2396808 (Clockwise)

Preceding gene: 167623915

Following gene: 167623917

Centisome position: 45.82

GC content: 42.49

Gene sequence:

>1758_bases
ATGGAAAGTAAATCGCCCTTTCAAGACACGATAGACAATGCATTGCAATTTGGTCAAGCATGGATGGATAGCTTCGGACA
GTCCGCTCAATCATGTATCGTAGAAACTCAAGTGGAAGATTTGGCACAATGGATGCGTTCATCGGTCGAACACCCAGTTA
ACTCTATTGAGCAACAAATGAATTGGTGGGGGCAACAAGTCAATCTATTTAACGATTGCATTATGAGTAGCTTACCAACA
GAAAAAGAGACTGATCGACGATTTAAAGATCCAGCGTGGAACGAACAGGCACTTTATAAATACATCAAAGAAAGTTACAA
GCTGGCTTGTAACAATGTTCAAAGCTCACTCGATAATACAGAAGGGCTAGATGACGAAACACGTCAGCGATTATCCTTTT
ATACTCGCCAGTACCTCAATGCTATGTCGCCGAGTAATTTTGTTGCTACCAATCCTGAAATAATGAAGCTAACCGTTGAA
AGCAAAGGGCAAAACCTGATCAAAGGGCTAGAACAACTTCAGAAAGATTTAGCGCAAAGTGCTGATACCTTAAATATTCG
CATGACAGACAAAAACGCCTTCACTATCGGCAAAAATATTGCCACAGCTCCGGGTAAAGTTGTATTTAAAAACGACCTGT
TTGAACTTATTCAATATCAAGCAACAACGGAGCAAGTCTACAAACGACCTTTGTTGGTAGTACCGCCTTTTGTGAATAAA
TTTTATATCATGGATCTGAGTCCTGAGCGTTCTTACACACAATGGCTAGTGAGCCAAGGGCATACCGTCTTCATGATCTC
TTGGATTAATCCGAATGCAGACATGGCAACAACTGACTTTGGTGACTACGTTACTCAGGGCATTATCCCTGCGTTAGATG
CAATAGAAGTTGAAACTGGTGAACGCGAAGTCAACGGTATCGGCTATTGTATTGGCGGAACACTGTTAACGACTGCAATG
GCTTATTTAGCAGGAAAGCGTCGCAAGCAAAGAGTCAAATCAGCAACCTTACTCACCACCATTTTAGATTTTGGCCAACC
TGGCGAACTGGGTGTATTCATAAACGAGCCACTTATTAGTAGCATAGAAGCGCAGAATAATGCTCGTGGCTACATGGATG
GACGACAAATGGCGGTGTCATTTAGCTTGTTAAGGGAAAATAGCCTGTATTGGAACTACTATGTGACCAATTACCTCAAA
GGTGAAAGCCCAATGGCGTTCGATCTACTTCATTGGAATTGTGACAATACGAATATTACCGCTGCGACACACAATCAGCT
ATTACGCCAAATGTACCTTGAAAATAAGCTTAAGGAACCTGGGGGGATAGCTATTGATGGGGTTAATATCGATCTTAGCA
AAGTGAAGTCTCCGAGCTATTTCTTATCCGCCATTGAAGATCATATTGCAGTCTGGGAAGGCACTTTTCGTGGAACAGAG
TTATTAAACGGTGATAACACGTTTGTGCTGGCCGAAAGTGGCCACATTGCAGGACCAATGAACCCGCCAAATGCCAATAA
ATATGGTTTTTGGACCAATAGCAATAACAAGCAGAGCCCGTTAACATGGCTCGCAGAGGCTGATAGTCATCAAGGTTCAT
GGTGGCCCCATTGGCAATCCTGGATCGATGAACGAAATTTTTCAGAAAAAATAGCTGCACGTTCACTAACTGGAAATTTA
GATGCTCCGGGTGAGTATGTAAAACAACGCATACAAGATGTAATAGCACTAAAAGAGGAGGTACACCATGGCGCTTGA

Upstream 100 bases:

>100_bases
GTGTAAAGCATAATAGTTTGGCGCGCTGTTTGCTCAATAAATACTGAGCAAGAGTGCGTCACCTTTTTATTCGTTTTAAT
TTGCCACTAAGGACGCCATC

Downstream 100 bases:

>100_bases
AGTGGGCCAGAGCTCGGCAATTGAAAAATGCTTAGATCAAGAATCGGTAGTCCAGTTTGCATCGTTAGCTGAGGATTATA
ACCCTGTGCATTTGGATGCT

Product: poly(R)-hydroxyalkanoic acid synthase, class I

Products: NA

Alternate protein names: PHA synthase; PHB synthase; Poly(3-hydroxyalkanoate) polymerase; PHA polymerase; Poly(3-hydroxybutyrate) polymerase; PHB polymerase; Polyhydroxyalkanoic acid synthase [H]

Number of amino acids: Translated: 585; Mature: 585

Protein sequence:

>585_residues
MESKSPFQDTIDNALQFGQAWMDSFGQSAQSCIVETQVEDLAQWMRSSVEHPVNSIEQQMNWWGQQVNLFNDCIMSSLPT
EKETDRRFKDPAWNEQALYKYIKESYKLACNNVQSSLDNTEGLDDETRQRLSFYTRQYLNAMSPSNFVATNPEIMKLTVE
SKGQNLIKGLEQLQKDLAQSADTLNIRMTDKNAFTIGKNIATAPGKVVFKNDLFELIQYQATTEQVYKRPLLVVPPFVNK
FYIMDLSPERSYTQWLVSQGHTVFMISWINPNADMATTDFGDYVTQGIIPALDAIEVETGEREVNGIGYCIGGTLLTTAM
AYLAGKRRKQRVKSATLLTTILDFGQPGELGVFINEPLISSIEAQNNARGYMDGRQMAVSFSLLRENSLYWNYYVTNYLK
GESPMAFDLLHWNCDNTNITAATHNQLLRQMYLENKLKEPGGIAIDGVNIDLSKVKSPSYFLSAIEDHIAVWEGTFRGTE
LLNGDNTFVLAESGHIAGPMNPPNANKYGFWTNSNNKQSPLTWLAEADSHQGSWWPHWQSWIDERNFSEKIAARSLTGNL
DAPGEYVKQRIQDVIALKEEVHHGA

Sequences:

>Translated_585_residues
MESKSPFQDTIDNALQFGQAWMDSFGQSAQSCIVETQVEDLAQWMRSSVEHPVNSIEQQMNWWGQQVNLFNDCIMSSLPT
EKETDRRFKDPAWNEQALYKYIKESYKLACNNVQSSLDNTEGLDDETRQRLSFYTRQYLNAMSPSNFVATNPEIMKLTVE
SKGQNLIKGLEQLQKDLAQSADTLNIRMTDKNAFTIGKNIATAPGKVVFKNDLFELIQYQATTEQVYKRPLLVVPPFVNK
FYIMDLSPERSYTQWLVSQGHTVFMISWINPNADMATTDFGDYVTQGIIPALDAIEVETGEREVNGIGYCIGGTLLTTAM
AYLAGKRRKQRVKSATLLTTILDFGQPGELGVFINEPLISSIEAQNNARGYMDGRQMAVSFSLLRENSLYWNYYVTNYLK
GESPMAFDLLHWNCDNTNITAATHNQLLRQMYLENKLKEPGGIAIDGVNIDLSKVKSPSYFLSAIEDHIAVWEGTFRGTE
LLNGDNTFVLAESGHIAGPMNPPNANKYGFWTNSNNKQSPLTWLAEADSHQGSWWPHWQSWIDERNFSEKIAARSLTGNL
DAPGEYVKQRIQDVIALKEEVHHGA
>Mature_585_residues
MESKSPFQDTIDNALQFGQAWMDSFGQSAQSCIVETQVEDLAQWMRSSVEHPVNSIEQQMNWWGQQVNLFNDCIMSSLPT
EKETDRRFKDPAWNEQALYKYIKESYKLACNNVQSSLDNTEGLDDETRQRLSFYTRQYLNAMSPSNFVATNPEIMKLTVE
SKGQNLIKGLEQLQKDLAQSADTLNIRMTDKNAFTIGKNIATAPGKVVFKNDLFELIQYQATTEQVYKRPLLVVPPFVNK
FYIMDLSPERSYTQWLVSQGHTVFMISWINPNADMATTDFGDYVTQGIIPALDAIEVETGEREVNGIGYCIGGTLLTTAM
AYLAGKRRKQRVKSATLLTTILDFGQPGELGVFINEPLISSIEAQNNARGYMDGRQMAVSFSLLRENSLYWNYYVTNYLK
GESPMAFDLLHWNCDNTNITAATHNQLLRQMYLENKLKEPGGIAIDGVNIDLSKVKSPSYFLSAIEDHIAVWEGTFRGTE
LLNGDNTFVLAESGHIAGPMNPPNANKYGFWTNSNNKQSPLTWLAEADSHQGSWWPHWQSWIDERNFSEKIAARSLTGNL
DAPGEYVKQRIQDVIALKEEVHHGA

Specific function: Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation [H]

COG id: COG3243

COG function: function code I; Poly(3-hydroxyalkanoate) synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHA/PHB synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010963
- InterPro:   IPR010941 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF07167 PhaC_N [H]

EC number: NA

Molecular weight: Translated: 66191; Mature: 66191

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESKSPFQDTIDNALQFGQAWMDSFGQSAQSCIVETQVEDLAQWMRSSVEHPVNSIEQQM
CCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NWWGQQVNLFNDCIMSSLPTEKETDRRFKDPAWNEQALYKYIKESYKLACNNVQSSLDNT
HHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
EGLDDETRQRLSFYTRQYLNAMSPSNFVATNPEIMKLTVESKGQNLIKGLEQLQKDLAQS
CCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHCC
ADTLNIRMTDKNAFTIGKNIATAPGKVVFKNDLFELIQYQATTEQVYKRPLLVVPPFVNK
CCEEEEEEECCCCEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCEEECCCCCE
FYIMDLSPERSYTQWLVSQGHTVFMISWINPNADMATTDFGDYVTQGIIPALDAIEVETG
EEEEECCCCHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHEEECCC
EREVNGIGYCIGGTLLTTAMAYLAGKRRKQRVKSATLLTTILDFGQPGELGVFINEPLIS
CCHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHH
SIEAQNNARGYMDGRQMAVSFSLLRENSLYWNYYVTNYLKGESPMAFDLLHWNCDNTNIT
HHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCEEEEEEEECCCCEEE
AATHNQLLRQMYLENKLKEPGGIAIDGVNIDLSKVKSPSYFLSAIEDHIAVWEGTFRGTE
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCE
LLNGDNTFVLAESGHIAGPMNPPNANKYGFWTNSNNKQSPLTWLAEADSHQGSWWPHWQS
EECCCCEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCCHHHH
WIDERNFSEKIAARSLTGNLDAPGEYVKQRIQDVIALKEEVHHGA
HHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MESKSPFQDTIDNALQFGQAWMDSFGQSAQSCIVETQVEDLAQWMRSSVEHPVNSIEQQM
CCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NWWGQQVNLFNDCIMSSLPTEKETDRRFKDPAWNEQALYKYIKESYKLACNNVQSSLDNT
HHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
EGLDDETRQRLSFYTRQYLNAMSPSNFVATNPEIMKLTVESKGQNLIKGLEQLQKDLAQS
CCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHCC
ADTLNIRMTDKNAFTIGKNIATAPGKVVFKNDLFELIQYQATTEQVYKRPLLVVPPFVNK
CCEEEEEEECCCCEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCEEECCCCCE
FYIMDLSPERSYTQWLVSQGHTVFMISWINPNADMATTDFGDYVTQGIIPALDAIEVETG
EEEEECCCCHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHEEECCC
EREVNGIGYCIGGTLLTTAMAYLAGKRRKQRVKSATLLTTILDFGQPGELGVFINEPLIS
CCHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHH
SIEAQNNARGYMDGRQMAVSFSLLRENSLYWNYYVTNYLKGESPMAFDLLHWNCDNTNIT
HHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCEEEEEEEECCCCEEE
AATHNQLLRQMYLENKLKEPGGIAIDGVNIDLSKVKSPSYFLSAIEDHIAVWEGTFRGTE
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCE
LLNGDNTFVLAESGHIAGPMNPPNANKYGFWTNSNNKQSPLTWLAEADSHQGSWWPHWQS
EECCCCEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCCHHHH
WIDERNFSEKIAARSLTGNLDAPGEYVKQRIQDVIALKEEVHHGA
HHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7582015; 9734305; 11481430 [H]