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The map label for this gene is eco [H]

Identifier: 167623883

GI number: 167623883

Start: 2347560

End: 2348141

Strand: Reverse

Name: eco [H]

Synonym: Shal_1953

Alternate gene names: 167623883

Gene position: 2348141-2347560 (Counterclockwise)

Preceding gene: 167623888

Following gene: 167623878

Centisome position: 44.92

GC content: 41.92

Gene sequence:

>582_bases
ATGACTTTATTCAATGCTGGTAATACGCGTTTTGCCCGTACACTTTTGGCTTCTTCTTTGATTCTTTCAGCTTTTTCATT
TAATGCGAATGCAACTAGCCCAGCTCACCCATCAGGATTAAATCAAAATATGATCGGTTCGCAGATGTATACGGCCGATG
ACTATAGTGTGACTAAAGAGACCAAGATGTTTCCTGAGCCACAAGCAGGTCAAGTCCAGCATATCTTGACTCTACCTAAG
CTAGACAATGAAGCTGACTACAGGGTGGAGATCCAGATCGGACAAACAAAAATGGTGGATTGTAATAAACACGGTTTAGT
GGGCGAATTGAAGCAACACACAGTGAAAGGTTGGGGATATAATTACTATCAAGTAGACAGCATTTCTGACGGTCCAAGCA
CTATGATGGCCTGCTTTGAGCAAACTACAACGGAAAAATTCCTGCCTATCCGTGATGATCTAATGTTGAAATACGATAGC
CGCTTACCAAAAGTATTCTATCTACCAGAAAATACCCAGGTGCGTTATCGCGTGTGGAAAGTTGAATCGCCGTTTAACTA
CTCTGGAGAAGCTACAAAATAG

Upstream 100 bases:

>100_bases
ATATATATACATTTTTTTGTCTTTTTATAACCCTTTTTGAAAACCGCAGCGTTTATAGAGGTATTGAACACAGACAATAC
CTTTTTATTTTGGAGATTTT

Downstream 100 bases:

>100_bases
CACCGCTTGTAATTTGATGAGATGAAACTAATCCAATAATGGACATAAAAAAAGCTACCCAAGGGTAGCTTTTTTATTAG
AAAGAATCATTTACACTTTA

Product: ecotin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MTLFNAGNTRFARTLLASSLILSAFSFNANATSPAHPSGLNQNMIGSQMYTADDYSVTKETKMFPEPQAGQVQHILTLPK
LDNEADYRVEIQIGQTKMVDCNKHGLVGELKQHTVKGWGYNYYQVDSISDGPSTMMACFEQTTTEKFLPIRDDLMLKYDS
RLPKVFYLPENTQVRYRVWKVESPFNYSGEATK

Sequences:

>Translated_193_residues
MTLFNAGNTRFARTLLASSLILSAFSFNANATSPAHPSGLNQNMIGSQMYTADDYSVTKETKMFPEPQAGQVQHILTLPK
LDNEADYRVEIQIGQTKMVDCNKHGLVGELKQHTVKGWGYNYYQVDSISDGPSTMMACFEQTTTEKFLPIRDDLMLKYDS
RLPKVFYLPENTQVRYRVWKVESPFNYSGEATK
>Mature_192_residues
TLFNAGNTRFARTLLASSLILSAFSFNANATSPAHPSGLNQNMIGSQMYTADDYSVTKETKMFPEPQAGQVQHILTLPKL
DNEADYRVEIQIGQTKMVDCNKHGLVGELKQHTVKGWGYNYYQVDSISDGPSTMMACFEQTTTEKFLPIRDDLMLKYDSR
LPKVFYLPENTQVRYRVWKVESPFNYSGEATK

Specific function: General inhibitor of family S1 serine proteases [H]

COG id: COG4574

COG function: function code R; Serine protease inhibitor ecotin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protease inhibitor I11 (ecotin) family [H]

Homologues:

Organism=Escherichia coli, GI1788538, Length=168, Percent_Identity=36.9047619047619, Blast_Score=114, Evalue=4e-27,

Paralogues:

None

Copy number: 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005658
- InterPro:   IPR023189
- InterPro:   IPR023084 [H]

Pfam domain/function: PF03974 Ecotin [H]

EC number: NA

Molecular weight: Translated: 21871; Mature: 21740

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLFNAGNTRFARTLLASSLILSAFSFNANATSPAHPSGLNQNMIGSQMYTADDYSVTKE
CEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCC
TKMFPEPQAGQVQHILTLPKLDNEADYRVEIQIGQTKMVDCNKHGLVGELKQHTVKGWGY
CCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEECCEEEEECCCCCCHHHHHHHEECCCCC
NYYQVDSISDGPSTMMACFEQTTTEKFLPIRDDLMLKYDSRLPKVFYLPENTQVRYRVWK
CEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEECCCCCEEEEEEEE
VESPFNYSGEATK
ECCCCCCCCCCCC
>Mature Secondary Structure 
TLFNAGNTRFARTLLASSLILSAFSFNANATSPAHPSGLNQNMIGSQMYTADDYSVTKE
EEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCC
TKMFPEPQAGQVQHILTLPKLDNEADYRVEIQIGQTKMVDCNKHGLVGELKQHTVKGWGY
CCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEECCEEEEECCCCCCHHHHHHHEECCCCC
NYYQVDSISDGPSTMMACFEQTTTEKFLPIRDDLMLKYDSRLPKVFYLPENTQVRYRVWK
CEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEECCCCCEEEEEEEE
VESPFNYSGEATK
ECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]