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The map label for this gene is aspS

Identifier: 167623848

GI number: 167623848

Start: 2304898

End: 2306694

Strand: Direct

Name: aspS

Synonym: Shal_1918

Alternate gene names: 167623848

Gene position: 2304898-2306694 (Clockwise)

Preceding gene: 167623847

Following gene: 167623849

Centisome position: 44.1

GC content: 45.46

Gene sequence:

>1797_bases
ATGCGCAGTCATTATTGTGGAGACGTCAATAAGTCTCACGTAGGTCAAGAAGTGACCCTAGTGGGTTGGGTTAATCGCAG
CCGAGATTTAGGCGGCGTTGTTTTTCTCGATCTTCGTGATAGAGAAGGTATCGTTCAGGTTGTTTATGATCCAGACCTTC
CTGAAGTGTTTGATGTTGCAAGCACACTTCGCAGCGAATTTTGTGTTCAGATTAAAGGCCTTGTAAGAGCAAGACCTGAC
AGCCAAATTAACGCCGATATGCGTACTGGCGAGGTTGAGATTTTAGGTCTAGAGCTAACAATTTTGAACAGCTCTGCGCC
ATTGCCAATCAACATGGACAAAAACCAGCACAATACTGAAGAGCAGCGTCTTAAGTACCGTTACTTAGATCTACGTCGTC
CAGAGATGGCAGATCGCATTGTTTTCCGCTCAAAAGTGACCAGTGCGGTAAGACGTTTCTTAGATGGCAACGGTTTCTTA
GATATTGAAACGCCAATTCTGACTAAAGCGACACCAGAAGGTGCACGTGATTACCTAGTACCTAGCCGTACTTATAAAGG
TCAGTTCTTTGCATTGCCACAATCACCACAACTGTTTAAGCAGTTGTTGATGATGTCTGGTTTTGACCGTTACTACCAAA
TCGTTAAGTGTTTCCGCGATGAAGACTTACGTGCTGACCGTCAGCCTGAATTTACTCAAATCGATATCGAAACGTCTTTC
ATGAGCTCTGATCAAGTGATGGCGAAGACTGAAGAGATGGTTCGTGGTTTATTCCAAGAGCTATTGAATGTTGATTTAGG
TGAGTTTCCTAAGATGACATTCGAAGAAGCGATGCGTCGTTTCGGTTCTGATAAGCCTGATTTACGTAACCCGCTTGAGT
TGATTGATGTTGCTGATATCGTTAAAGAAGTTGAGTTTGCAGTATTTAATGGCCCAGCAAACGATCCTGAAGGTCGTGTT
GCAGTATTAAGCATTCCAGGTGGCGCTAAGCTGTCACGTAAACAGTTAGATGAATACGCAAAGTACGTCACTATCTATGG
CGCGAAAGGCCTAGCTTGGATGAAGGTCAATGACCTTGATAAGGGCATGGAAGGCATTCAGTCTCCAGTACTTAAGTTCT
TAAGCGAAGATGTTGTTAAGGCATTGCTTGAGCGCACTGGCGCACAAACTGGCGATCTAATTCTATTTGGTGCAGATAAA
GCCAATATCGTTGCTGAATCGATGGGCGCACTGCGTTTAAAAGCGGGCGAAGACTTCGACTTGTTACAAGGCGAGTGGAA
GCCACTTTGGGTTGTTGACTTCCCAATGTTTGAGCGCACATCTGATGGCGGCCTGCATGCAATGCACCATCCATTCACAG
CGCCAAGCAACATGACACCAGAAGAGCTAGAAGCGAACCCAATCGCTGCTATTTCTGATGCATACGATATGGTATTAAAC
GGCTGTGAGTTAGGCGGTGGTTCTGTTCGTATTCACGATAGCAAAATGCAGTCAGCGGTATTTAGAATACTAGGCATTAA
TGACGAAGAAGCGACTGAGAAGTTTGGTTTCTTACTTGAAGCATTACGCTACGGTACGCCGCCGCATGCTGGTTTGGCCT
TCGGCCTAGACCGTATCATCATGTTGATGACGGGTGCGAGTTCAATCCGTGACGTGATGGCGTTCCCTAAGACAACGACG
GCAGCTTGTCCATTAACGAACGCACCAGGATTTGCAAATCCGGTACAACTAGCTGAACTTGGTGTCAGTGTTGTCGAAGC
GGAAACTAAAGATTCTGAAACAAAAGACGCTGAATAA

Upstream 100 bases:

>100_bases
AGTTATTTGGAAAACGGCAATATTTCTCTATAATGCCGCTTTTGTTTTATTTTGAACCAGATCCTCAAGCATCGCTTTGC
GGAATAAAGGAAAGAGTTAA

Downstream 100 bases:

>100_bases
TAAAGCGTAATAAGAGCCGAGTTAAGACTCGGCTTTTTTTTCGACTAATTGAACCCCATCAGTATGATAATTCCCCCTAT
ACCCAAGTCACTTGCATAAT

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS

Number of amino acids: Translated: 598; Mature: 598

Protein sequence:

>598_residues
MRSHYCGDVNKSHVGQEVTLVGWVNRSRDLGGVVFLDLRDREGIVQVVYDPDLPEVFDVASTLRSEFCVQIKGLVRARPD
SQINADMRTGEVEILGLELTILNSSAPLPINMDKNQHNTEEQRLKYRYLDLRRPEMADRIVFRSKVTSAVRRFLDGNGFL
DIETPILTKATPEGARDYLVPSRTYKGQFFALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDIETSF
MSSDQVMAKTEEMVRGLFQELLNVDLGEFPKMTFEEAMRRFGSDKPDLRNPLELIDVADIVKEVEFAVFNGPANDPEGRV
AVLSIPGGAKLSRKQLDEYAKYVTIYGAKGLAWMKVNDLDKGMEGIQSPVLKFLSEDVVKALLERTGAQTGDLILFGADK
ANIVAESMGALRLKAGEDFDLLQGEWKPLWVVDFPMFERTSDGGLHAMHHPFTAPSNMTPEELEANPIAAISDAYDMVLN
GCELGGGSVRIHDSKMQSAVFRILGINDEEATEKFGFLLEALRYGTPPHAGLAFGLDRIIMLMTGASSIRDVMAFPKTTT
AACPLTNAPGFANPVQLAELGVSVVEAETKDSETKDAE

Sequences:

>Translated_598_residues
MRSHYCGDVNKSHVGQEVTLVGWVNRSRDLGGVVFLDLRDREGIVQVVYDPDLPEVFDVASTLRSEFCVQIKGLVRARPD
SQINADMRTGEVEILGLELTILNSSAPLPINMDKNQHNTEEQRLKYRYLDLRRPEMADRIVFRSKVTSAVRRFLDGNGFL
DIETPILTKATPEGARDYLVPSRTYKGQFFALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDIETSF
MSSDQVMAKTEEMVRGLFQELLNVDLGEFPKMTFEEAMRRFGSDKPDLRNPLELIDVADIVKEVEFAVFNGPANDPEGRV
AVLSIPGGAKLSRKQLDEYAKYVTIYGAKGLAWMKVNDLDKGMEGIQSPVLKFLSEDVVKALLERTGAQTGDLILFGADK
ANIVAESMGALRLKAGEDFDLLQGEWKPLWVVDFPMFERTSDGGLHAMHHPFTAPSNMTPEELEANPIAAISDAYDMVLN
GCELGGGSVRIHDSKMQSAVFRILGINDEEATEKFGFLLEALRYGTPPHAGLAFGLDRIIMLMTGASSIRDVMAFPKTTT
AACPLTNAPGFANPVQLAELGVSVVEAETKDSETKDAE
>Mature_598_residues
MRSHYCGDVNKSHVGQEVTLVGWVNRSRDLGGVVFLDLRDREGIVQVVYDPDLPEVFDVASTLRSEFCVQIKGLVRARPD
SQINADMRTGEVEILGLELTILNSSAPLPINMDKNQHNTEEQRLKYRYLDLRRPEMADRIVFRSKVTSAVRRFLDGNGFL
DIETPILTKATPEGARDYLVPSRTYKGQFFALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDIETSF
MSSDQVMAKTEEMVRGLFQELLNVDLGEFPKMTFEEAMRRFGSDKPDLRNPLELIDVADIVKEVEFAVFNGPANDPEGRV
AVLSIPGGAKLSRKQLDEYAKYVTIYGAKGLAWMKVNDLDKGMEGIQSPVLKFLSEDVVKALLERTGAQTGDLILFGADK
ANIVAESMGALRLKAGEDFDLLQGEWKPLWVVDFPMFERTSDGGLHAMHHPFTAPSNMTPEELEANPIAAISDAYDMVLN
GCELGGGSVRIHDSKMQSAVFRILGINDEEATEKFGFLLEALRYGTPPHAGLAFGLDRIIMLMTGASSIRDVMAFPKTTT
AACPLTNAPGFANPVQLAELGVSVVEAETKDSETKDAE

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI40789249, Length=622, Percent_Identity=38.5852090032154, Blast_Score=400, Evalue=1e-111,
Organism=Homo sapiens, GI5031815, Length=256, Percent_Identity=27.734375, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI194272210, Length=256, Percent_Identity=27.734375, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI45439306, Length=268, Percent_Identity=26.4925373134328, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI226491502, Length=255, Percent_Identity=27.4509803921569, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI4758762, Length=258, Percent_Identity=25.1937984496124, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1788173, Length=587, Percent_Identity=67.4616695059625, Blast_Score=843, Evalue=0.0,
Organism=Escherichia coli, GI1790571, Length=294, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789256, Length=292, Percent_Identity=28.0821917808219, Blast_Score=94, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI32566633, Length=610, Percent_Identity=34.0983606557377, Blast_Score=322, Evalue=3e-88,
Organism=Caenorhabditis elegans, GI71984122, Length=307, Percent_Identity=28.3387622149837, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71994340, Length=144, Percent_Identity=31.25, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17535927, Length=140, Percent_Identity=32.1428571428571, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17535925, Length=140, Percent_Identity=32.1428571428571, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17551876, Length=278, Percent_Identity=26.6187050359712, Blast_Score=82, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6325153, Length=313, Percent_Identity=38.0191693290735, Blast_Score=187, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6323011, Length=268, Percent_Identity=27.2388059701493, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324256, Length=123, Percent_Identity=28.4552845528455, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320242, Length=143, Percent_Identity=27.972027972028, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584738, Length=629, Percent_Identity=35.2941176470588, Blast_Score=338, Evalue=5e-93,
Organism=Drosophila melanogaster, GI24640849, Length=255, Percent_Identity=27.4509803921569, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24640851, Length=255, Percent_Identity=27.4509803921569, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17136276, Length=253, Percent_Identity=28.8537549407115, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19921528, Length=252, Percent_Identity=25.7936507936508, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYD_SHEHH (B0TSA3)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001674142.1
- ProteinModelPortal:   B0TSA3
- SMR:   B0TSA3
- GeneID:   5904358
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_1918
- HOGENOM:   HBG396032
- OMA:   AFPKTQQ
- ProtClustDB:   PRK00476
- BioCyc:   SHAL458817:SHAL_1918-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00044_B
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:3.30.1360.30
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PANTHER:   PTHR22594:SF5
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00459

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.12

Molecular weight: Translated: 66590; Mature: 66590

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSHYCGDVNKSHVGQEVTLVGWVNRSRDLGGVVFLDLRDREGIVQVVYDPDLPEVFDVA
CCCCCCCCCCHHHCCCEEEEEEECCCCCCCCCEEEEEEECCCCEEEEEECCCCHHHHHHH
STLRSEFCVQIKGLVRARPDSQINADMRTGEVEILGLELTILNSSAPLPINMDKNQHNTE
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCEEECCCCCCCCH
EQRLKYRYLDLRRPEMADRIVFRSKVTSAVRRFLDGNGFLDIETPILTKATPEGARDYLV
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCCCCCCCCC
PSRTYKGQFFALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDIETSF
CCCCCCCEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHH
MSSDQVMAKTEEMVRGLFQELLNVDLGEFPKMTFEEAMRRFGSDKPDLRNPLELIDVADI
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
VKEVEFAVFNGPANDPEGRVAVLSIPGGAKLSRKQLDEYAKYVTIYGAKGLAWMKVNDLD
HHHHHHEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHEEEEECCCCEEEEEECCHH
KGMEGIQSPVLKFLSEDVVKALLERTGAQTGDLILFGADKANIVAESMGALRLKAGEDFD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHCCCCEEEECCCCCH
LLQGEWKPLWVVDFPMFERTSDGGLHAMHHPFTAPSNMTPEELEANPIAAISDAYDMVLN
HHCCCCCEEEEEECCCCCCCCCCCCEECCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHC
GCELGGGSVRIHDSKMQSAVFRILGINDEEATEKFGFLLEALRYGTPPHAGLAFGLDRII
CCCCCCCEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
MLMTGASSIRDVMAFPKTTTAACPLTNAPGFANPVQLAELGVSVVEAETKDSETKDAE
HHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCHHHEECCCCCCCCCCCC
>Mature Secondary Structure
MRSHYCGDVNKSHVGQEVTLVGWVNRSRDLGGVVFLDLRDREGIVQVVYDPDLPEVFDVA
CCCCCCCCCCHHHCCCEEEEEEECCCCCCCCCEEEEEEECCCCEEEEEECCCCHHHHHHH
STLRSEFCVQIKGLVRARPDSQINADMRTGEVEILGLELTILNSSAPLPINMDKNQHNTE
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCEEECCCCCCCCH
EQRLKYRYLDLRRPEMADRIVFRSKVTSAVRRFLDGNGFLDIETPILTKATPEGARDYLV
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCCCCCCCCC
PSRTYKGQFFALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDIETSF
CCCCCCCEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHH
MSSDQVMAKTEEMVRGLFQELLNVDLGEFPKMTFEEAMRRFGSDKPDLRNPLELIDVADI
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
VKEVEFAVFNGPANDPEGRVAVLSIPGGAKLSRKQLDEYAKYVTIYGAKGLAWMKVNDLD
HHHHHHEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHEEEEECCCCEEEEEECCHH
KGMEGIQSPVLKFLSEDVVKALLERTGAQTGDLILFGADKANIVAESMGALRLKAGEDFD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHCCCCEEEECCCCCH
LLQGEWKPLWVVDFPMFERTSDGGLHAMHHPFTAPSNMTPEELEANPIAAISDAYDMVLN
HHCCCCCEEEEEECCCCCCCCCCCCEECCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHC
GCELGGGSVRIHDSKMQSAVFRILGINDEEATEKFGFLLEALRYGTPPHAGLAFGLDRII
CCCCCCCEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
MLMTGASSIRDVMAFPKTTTAACPLTNAPGFANPVQLAELGVSVVEAETKDSETKDAE
HHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCHHHEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA