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The map label for this gene is minC

Identifier: 167623766

GI number: 167623766

Start: 2193259

End: 2193924

Strand: Reverse

Name: minC

Synonym: Shal_1836

Alternate gene names: 167623766

Gene position: 2193924-2193259 (Counterclockwise)

Preceding gene: 167623770

Following gene: 167623765

Centisome position: 41.97

GC content: 44.44

Gene sequence:

>666_bases
ATGCAAACACCTAGCCTCGAATTAAAAGGCTCTTCTTTTACTCTTTCTGTACTGCATATCAACAGTAATGATATGGCAGT
TATAGCAGCTGAGTTAGATGCTAAGCTTGCCATTGCACCACAGTTTTTTCTTGGTGCGCCTTTAGTGGTTAATCTTAGCG
CCATACAAGCCACTGATTTTGACATATTGGGTTTGAAAGAGATATTAACCAATCGCCAATTGATTATTGTTGGCATAACC
AGTGCGTGCCCAGAACTGACTAAACAAGCGAAATCCATTGGTCTCGCGACCGTTAAAACAGGTAAAGAAGCGACTTCACA
ACCGCAAATGCCCAAAACGACCAAAATCGTCAAACAAAATGTCCGCTCAGGGCAGCAAATCTATGCCAAGAATGCAGATT
TGATTATTGTCGGCGCAGTGGGTAACGGTGCTGAAGTGATAGCCGATGGCAGTATCCATATATACGGTACATTGCGTGGG
AAAGCGATGGCTGGCGCTGGTGGCGATAGACACGCTGTTATCATGGCACAAAAAATTGAAGCAGAACTGGTATCGATTGC
AGGTCAATACTGGTTAACTGAAAATCTTCAGCAAAACGGAGCCGCTCTAAGCGGTTGTATTCGCCTAGAGGGCGAATCGC
TTACGGTTGAATCATTGCCTCTGTAA

Upstream 100 bases:

>100_bases
TATTCAACTTGCCAGCTACGAAAGCACACTATACCATGGACCGTTAGGAATATAATGGATATCGGCTTTGTGCTGATTTT
TTCTAGAGAGCAATACAGGA

Downstream 100 bases:

>100_bases
GAGCGCAAAATTGAAAGGATTATTATAAATGGCGCAAATTATTGTTGTCACATCGGGTAAAGGTGGCGTGGGTAAAACCA
CCTCAAGTGCTGCAATTGCT

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MQTPSLELKGSSFTLSVLHINSNDMAVIAAELDAKLAIAPQFFLGAPLVVNLSAIQATDFDILGLKEILTNRQLIIVGIT
SACPELTKQAKSIGLATVKTGKEATSQPQMPKTTKIVKQNVRSGQQIYAKNADLIIVGAVGNGAEVIADGSIHIYGTLRG
KAMAGAGGDRHAVIMAQKIEAELVSIAGQYWLTENLQQNGAALSGCIRLEGESLTVESLPL

Sequences:

>Translated_221_residues
MQTPSLELKGSSFTLSVLHINSNDMAVIAAELDAKLAIAPQFFLGAPLVVNLSAIQATDFDILGLKEILTNRQLIIVGIT
SACPELTKQAKSIGLATVKTGKEATSQPQMPKTTKIVKQNVRSGQQIYAKNADLIIVGAVGNGAEVIADGSIHIYGTLRG
KAMAGAGGDRHAVIMAQKIEAELVSIAGQYWLTENLQQNGAALSGCIRLEGESLTVESLPL
>Mature_221_residues
MQTPSLELKGSSFTLSVLHINSNDMAVIAAELDAKLAIAPQFFLGAPLVVNLSAIQATDFDILGLKEILTNRQLIIVGIT
SACPELTKQAKSIGLATVKTGKEATSQPQMPKTTKIVKQNVRSGQQIYAKNADLIIVGAVGNGAEVIADGSIHIYGTLRG
KAMAGAGGDRHAVIMAQKIEAELVSIAGQYWLTENLQQNGAALSGCIRLEGESLTVESLPL

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family

Homologues:

Organism=Escherichia coli, GI1787424, Length=232, Percent_Identity=38.7931034482759, Blast_Score=155, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINC_SHEHH (B0TRI3)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001674060.1
- ProteinModelPortal:   B0TRI3
- SMR:   B0TRI3
- GeneID:   5904190
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_1836
- HOGENOM:   HBG399077
- OMA:   KGDTKAR
- ProtClustDB:   PRK04804
- BioCyc:   SHAL458817:SHAL_1836-MONOMER
- HAMAP:   MF_00267
- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526
- Gene3D:   G3DSA:2.160.20.70
- TIGRFAMs:   TIGR01222

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N; SSF63848 MinC_C

EC number: NA

Molecular weight: Translated: 23234; Mature: 23234

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTPSLELKGSSFTLSVLHINSNDMAVIAAELDAKLAIAPQFFLGAPLVVNLSAIQATDF
CCCCCEEEECCEEEEEEEEECCCCEEEEEEECCCEEEECCHHHHCCCEEEEEEEEEECCC
DILGLKEILTNRQLIIVGITSACPELTKQAKSIGLATVKTGKEATSQPQMPKTTKIVKQN
CEECHHHHHCCCCEEEEEECCCCHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHH
VRSGQQIYAKNADLIIVGAVGNGAEVIADGSIHIYGTLRGKAMAGAGGDRHAVIMAQKIE
HCCCCEEEECCCCEEEEEECCCCCEEEECCCEEEEEEEECEEEECCCCCCEEEEEEEHHH
AELVSIAGQYWLTENLQQNGAALSGCIRLEGESLTVESLPL
HHHHHHHHHHHHHHCHHHCCCEEEEEEEECCCEEEEEECCC
>Mature Secondary Structure
MQTPSLELKGSSFTLSVLHINSNDMAVIAAELDAKLAIAPQFFLGAPLVVNLSAIQATDF
CCCCCEEEECCEEEEEEEEECCCCEEEEEEECCCEEEECCHHHHCCCEEEEEEEEEECCC
DILGLKEILTNRQLIIVGITSACPELTKQAKSIGLATVKTGKEATSQPQMPKTTKIVKQN
CEECHHHHHCCCCEEEEEECCCCHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHH
VRSGQQIYAKNADLIIVGAVGNGAEVIADGSIHIYGTLRGKAMAGAGGDRHAVIMAQKIE
HCCCCEEEECCCCEEEEEECCCCCEEEECCCEEEEEEEECEEEECCCCCCEEEEEEEHHH
AELVSIAGQYWLTENLQQNGAALSGCIRLEGESLTVESLPL
HHHHHHHHHHHHHHCHHHCCCEEEEEEEECCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA