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The map label for this gene is sdaA [H]

Identifier: 167623539

GI number: 167623539

Start: 1931674

End: 1933050

Strand: Reverse

Name: sdaA [H]

Synonym: Shal_1608

Alternate gene names: 167623539

Gene position: 1933050-1931674 (Counterclockwise)

Preceding gene: 167623543

Following gene: 167623537

Centisome position: 36.98

GC content: 48.58

Gene sequence:

>1377_bases
ATGATTAGTGTATTCGACATGTTCAAAATTGGCATCGGACCATCAAGTTCTCACACTGTGGGTCCCATGAAAGCCGGCAA
TATATTTATCGAACAACTACAAGCATTAGATCACCTCGACAGCATAGATGAGTTACGTTCAGAACTGTTTGGCTCTTTAG
GTCAAACAGGTAAAGGCCATGGTACAGGTAAAGCGGTGATCTTAGGCCTAATGGGTGAAGCCCCTGATACCGTTGATACA
GACCGCATTGATGGAATTCTAGAGCAAGTCAGTAACAATGAACGCTTAGTCCTTGCCTCTGGTCGAGAGGTACTTTTTAC
ACGTGCTAACGGCATTATTTACCATAGACGTAAGAGCCTCCCCGCTCACGCCAATGCTATGACCTTATATGCATATAAAG
ATGGCCAATGCGTTTATGATCGCACCTATTACTCTGTCGGCGGCGGGTTCATTCTCGATGAGGATGAAATTAAAGCCCAA
GATGCTTCACCTGCGGCTCCCATTAAATCGGCTCCTTTTGATTTCGACTCGGCCCAGCATTTGCTCGAGCTTTGCACTGA
AAATGGCTTCAGCATTTCGTCACTCATGATGGCCAATGAACTGAGCATTGCCGATGCTGACGATATTCACGACAATTTGT
GGCAAATATGGCAAACCATGAAGACCTGTGTCGAACGTGGCTACCAAAAAGAAGGCATACTGCCTGGCGGGCTCAAGCTT
AGACGCCGTGCACCTTCACTTCACCGCCGTTTGAAGGCAGAAGGCAGAAACTGTGTTGATCCACTCACGGCGATGGACTG
GGTCGACCTATTTGCACTTTCAGTTAACGAGCAAAATGCCGCCGGCGATCGCGTTGTCACCGCTCCAACCAATGGCGCTG
CAGGTATTATTCCGGCGGTACTGTGTTATTACGACATGTTTGTGCAAGAAGTCGATAGAGACGTATGCTCTCGCTACCTG
CTTACCGCCGCTGCAATTGGTATTCTTTATAAGAAGAACGCATCTATCTCTGGCGCTGAGGTCGGCTGTCAGGGTGAAGT
TGGTGTAGCTTGCTCTATGGCCGCTGCCGCGCTGACTGAGATCATGGGCGGCACTGTTGAACATGTTGAGAATGCCGCAG
AAATCGGTATGGAGCATAACCTAGGATTAACCTGCGACCCTGTAGGCGGCCTAGTACAGGTGCCTTGTATCGAGCGTAAT
GCTATGGGTGCGGTAAAAGCGATTAATGCCTCTCGCATGGCGATGCGAGGTGATGGTAACCATAAGGTCTCACTCGACAA
GGTGATTAAGACCATGATGGATACCGGTAAAGATATGCGTAGTAAGTACAAAGAAACCGCTAAGGGCGGCCTAGCGGTTA
ATATCGTAGAGTGTTAA

Upstream 100 bases:

>100_bases
ATATATCAAGAATAGAGTCATTCCTCCATTGAGTTCTATCTTCAGTTATATCTTAGCGAATGGGTAATAATTATAACGAC
TAGAGTAATAAAGGTTTAGC

Downstream 100 bases:

>100_bases
TCACTGACTTTTGTATAGTTGGTATAACTCAATAGCTTAACGTCTAAAAACAAAAAACCTCGCAATAGCGAGGTTTTTTA
TGCTTTTATGTTTTGTTAGC

Product: L-serine dehydratase 1

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MISVFDMFKIGIGPSSSHTVGPMKAGNIFIEQLQALDHLDSIDELRSELFGSLGQTGKGHGTGKAVILGLMGEAPDTVDT
DRIDGILEQVSNNERLVLASGREVLFTRANGIIYHRRKSLPAHANAMTLYAYKDGQCVYDRTYYSVGGGFILDEDEIKAQ
DASPAAPIKSAPFDFDSAQHLLELCTENGFSISSLMMANELSIADADDIHDNLWQIWQTMKTCVERGYQKEGILPGGLKL
RRRAPSLHRRLKAEGRNCVDPLTAMDWVDLFALSVNEQNAAGDRVVTAPTNGAAGIIPAVLCYYDMFVQEVDRDVCSRYL
LTAAAIGILYKKNASISGAEVGCQGEVGVACSMAAAALTEIMGGTVEHVENAAEIGMEHNLGLTCDPVGGLVQVPCIERN
AMGAVKAINASRMAMRGDGNHKVSLDKVIKTMMDTGKDMRSKYKETAKGGLAVNIVEC

Sequences:

>Translated_458_residues
MISVFDMFKIGIGPSSSHTVGPMKAGNIFIEQLQALDHLDSIDELRSELFGSLGQTGKGHGTGKAVILGLMGEAPDTVDT
DRIDGILEQVSNNERLVLASGREVLFTRANGIIYHRRKSLPAHANAMTLYAYKDGQCVYDRTYYSVGGGFILDEDEIKAQ
DASPAAPIKSAPFDFDSAQHLLELCTENGFSISSLMMANELSIADADDIHDNLWQIWQTMKTCVERGYQKEGILPGGLKL
RRRAPSLHRRLKAEGRNCVDPLTAMDWVDLFALSVNEQNAAGDRVVTAPTNGAAGIIPAVLCYYDMFVQEVDRDVCSRYL
LTAAAIGILYKKNASISGAEVGCQGEVGVACSMAAAALTEIMGGTVEHVENAAEIGMEHNLGLTCDPVGGLVQVPCIERN
AMGAVKAINASRMAMRGDGNHKVSLDKVIKTMMDTGKDMRSKYKETAKGGLAVNIVEC
>Mature_458_residues
MISVFDMFKIGIGPSSSHTVGPMKAGNIFIEQLQALDHLDSIDELRSELFGSLGQTGKGHGTGKAVILGLMGEAPDTVDT
DRIDGILEQVSNNERLVLASGREVLFTRANGIIYHRRKSLPAHANAMTLYAYKDGQCVYDRTYYSVGGGFILDEDEIKAQ
DASPAAPIKSAPFDFDSAQHLLELCTENGFSISSLMMANELSIADADDIHDNLWQIWQTMKTCVERGYQKEGILPGGLKL
RRRAPSLHRRLKAEGRNCVDPLTAMDWVDLFALSVNEQNAAGDRVVTAPTNGAAGIIPAVLCYYDMFVQEVDRDVCSRYL
LTAAAIGILYKKNASISGAEVGCQGEVGVACSMAAAALTEIMGGTVEHVENAAEIGMEHNLGLTCDPVGGLVQVPCIERN
AMGAVKAINASRMAMRGDGNHKVSLDKVIKTMMDTGKDMRSKYKETAKGGLAVNIVEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=459, Percent_Identity=57.2984749455338, Blast_Score=529, Evalue=1e-151,
Organism=Escherichia coli, GI1789161, Length=459, Percent_Identity=54.6840958605665, Blast_Score=505, Evalue=1e-144,
Organism=Escherichia coli, GI48994925, Length=458, Percent_Identity=54.8034934497817, Blast_Score=494, Evalue=1e-141,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 49355; Mature: 49355

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVFDMFKIGIGPSSSHTVGPMKAGNIFIEQLQALDHLDSIDELRSELFGSLGQTGKGH
CCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GTGKAVILGLMGEAPDTVDTDRIDGILEQVSNNERLVLASGREVLFTRANGIIYHRRKSL
CCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCEEEEECCCC
PAHANAMTLYAYKDGQCVYDRTYYSVGGGFILDEDEIKAQDASPAAPIKSAPFDFDSAQH
CCCCCEEEEEEEECCCEEEECEEEECCCCEEECCHHHCCCCCCCCCCCCCCCCCCHHHHH
LLELCTENGFSISSLMMANELSIADADDIHDNLWQIWQTMKTCVERGYQKEGILPGGLKL
HHHHHHCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
RRRAPSLHRRLKAEGRNCVDPLTAMDWVDLFALSVNEQNAAGDRVVTAPTNGAAGIIPAV
HHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHEECCCCCCCCCEEEECCCCCCHHHHHHH
LCYYDMFVQEVDRDVCSRYLLTAAAIGILYKKNASISGAEVGCQGEVGVACSMAAAALTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
IMGGTVEHVENAAEIGMEHNLGLTCDPVGGLVQVPCIERNAMGAVKAINASRMAMRGDGN
HHCCHHHHHHHHHHHCCCCCCCEEECCCCCEEECCCCCCCCCCHHHHCCHHHHEEECCCC
HKVSLDKVIKTMMDTGKDMRSKYKETAKGGLAVNIVEC
CEEEHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECC
>Mature Secondary Structure
MISVFDMFKIGIGPSSSHTVGPMKAGNIFIEQLQALDHLDSIDELRSELFGSLGQTGKGH
CCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GTGKAVILGLMGEAPDTVDTDRIDGILEQVSNNERLVLASGREVLFTRANGIIYHRRKSL
CCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCEEEEECCCC
PAHANAMTLYAYKDGQCVYDRTYYSVGGGFILDEDEIKAQDASPAAPIKSAPFDFDSAQH
CCCCCEEEEEEEECCCEEEECEEEECCCCEEECCHHHCCCCCCCCCCCCCCCCCCHHHHH
LLELCTENGFSISSLMMANELSIADADDIHDNLWQIWQTMKTCVERGYQKEGILPGGLKL
HHHHHHCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
RRRAPSLHRRLKAEGRNCVDPLTAMDWVDLFALSVNEQNAAGDRVVTAPTNGAAGIIPAV
HHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHEECCCCCCCCCEEEECCCCCCHHHHHHH
LCYYDMFVQEVDRDVCSRYLLTAAAIGILYKKNASISGAEVGCQGEVGVACSMAAAALTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
IMGGTVEHVENAAEIGMEHNLGLTCDPVGGLVQVPCIERNAMGAVKAINASRMAMRGDGN
HHCCHHHHHHHHHHHCCCCCCCEEECCCCCEEECCCCCCCCCCHHHHCCHHHHEEECCCC
HKVSLDKVIKTMMDTGKDMRSKYKETAKGGLAVNIVEC
CEEEHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]