Click here to switch to the map view.

The map label for this gene is ywbI [H]

Identifier: 167623467

GI number: 167623467

Start: 1851923

End: 1852834

Strand: Reverse

Name: ywbI [H]

Synonym: Shal_1536

Alternate gene names: 167623467

Gene position: 1852834-1851923 (Counterclockwise)

Preceding gene: 167623469

Following gene: 167623461

Centisome position: 35.45

GC content: 43.97

Gene sequence:

>912_bases
ATGCAGCTTAGGAAAATAGATAGAGTCGACATGGATATTAGGCAATTAAAATACTTAGATGCATTAATTACTGCAGGTAG
CTTCACCAAAGCCGCCGAGCGGCTCAATATGGCACAGCCCGCATTGAGTCAAAGTATTAAGCGCCTAGAGCAAGAGTTAG
GAGTCACTCTAGTTGATAGAGGTGCCAATAAAAGCAGTAAGACGCTTTCGTTAACTGCCGAGGGCAGCGCACTGCATCAA
CATGCCAAATTAATCATTAAAAATATGGCACAGGCTGAAGCGCACATAAAATCGATGGCCAACCTAACTATGGGCGAAGT
GAGAGTCGCGGTGCCCGGTATGCTAGGCTCATTTTATCTACCCAGACGTTTAATGGCATTTCGGCACCGCCACCCTGAAC
TTAAATTGTCACTATTTGAAGGCGGTACTCGCGATACTTTAAAAATGCTACAGAATGAAGATGTTGATATCGCTATTATT
ACCGCCAATGATCTAACCGATGAGTTTGACAGTCACCTTCTTTTGCAAGAGCAAATGGTGGTTGCGGTTGGTAGAGAGCA
CCCGTTAGCCAAGTCTGATGCCGTGACTTTAGAGGAGTTTTTTCAACATGAACTGGTATTCTTTAAGCCCGGATACTTCC
ACCGAGAGTGGATGCTAGAACAAGCAGAGCAGTTAGGCCTCACTGCAAATATTGCTTTTGAAACTAATCTGATTAACCTC
ATTAAACAAGTGGTTGCCCAAGAATATGGCATTACCACAGTGTTAGAGATGGTGATAGAAAAGCACGATAACATTTGTGC
AAAACCTTTCATCCCACCTATTTTTCTCGACTTGCATATCGCTTGGAAAAAACAGCGCCCTATCAGCCAAGCCGACAGGG
CATTCGTCGAGTTTCTAATGCTAAACCGTTAG

Upstream 100 bases:

>100_bases
AATAGTTATTGATTTTTGTTATAGTGAATTAAAAGTAGATCCTTATTAAAGGGCAGTTTTAATATTGAGCCGAAAGATAA
GCTCTGCCCACCACAAAATA

Downstream 100 bases:

>100_bases
CTCGCATCCAATTGATTTTCTGGCATGGCATCAATAAACATCAGCCAGGTTAAGCTGTGCGCGTTTTCGCGCTCAATATA
TTATACCAATCACATATTTA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MQLRKIDRVDMDIRQLKYLDALITAGSFTKAAERLNMAQPALSQSIKRLEQELGVTLVDRGANKSSKTLSLTAEGSALHQ
HAKLIIKNMAQAEAHIKSMANLTMGEVRVAVPGMLGSFYLPRRLMAFRHRHPELKLSLFEGGTRDTLKMLQNEDVDIAII
TANDLTDEFDSHLLLQEQMVVAVGREHPLAKSDAVTLEEFFQHELVFFKPGYFHREWMLEQAEQLGLTANIAFETNLINL
IKQVVAQEYGITTVLEMVIEKHDNICAKPFIPPIFLDLHIAWKKQRPISQADRAFVEFLMLNR

Sequences:

>Translated_303_residues
MQLRKIDRVDMDIRQLKYLDALITAGSFTKAAERLNMAQPALSQSIKRLEQELGVTLVDRGANKSSKTLSLTAEGSALHQ
HAKLIIKNMAQAEAHIKSMANLTMGEVRVAVPGMLGSFYLPRRLMAFRHRHPELKLSLFEGGTRDTLKMLQNEDVDIAII
TANDLTDEFDSHLLLQEQMVVAVGREHPLAKSDAVTLEEFFQHELVFFKPGYFHREWMLEQAEQLGLTANIAFETNLINL
IKQVVAQEYGITTVLEMVIEKHDNICAKPFIPPIFLDLHIAWKKQRPISQADRAFVEFLMLNR
>Mature_303_residues
MQLRKIDRVDMDIRQLKYLDALITAGSFTKAAERLNMAQPALSQSIKRLEQELGVTLVDRGANKSSKTLSLTAEGSALHQ
HAKLIIKNMAQAEAHIKSMANLTMGEVRVAVPGMLGSFYLPRRLMAFRHRHPELKLSLFEGGTRDTLKMLQNEDVDIAII
TANDLTDEFDSHLLLQEQMVVAVGREHPLAKSDAVTLEEFFQHELVFFKPGYFHREWMLEQAEQLGLTANIAFETNLINL
IKQVVAQEYGITTVLEMVIEKHDNICAKPFIPPIFLDLHIAWKKQRPISQADRAFVEFLMLNR

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=262, Percent_Identity=30.1526717557252, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1790399, Length=266, Percent_Identity=24.812030075188, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI145693105, Length=292, Percent_Identity=25, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786401, Length=295, Percent_Identity=26.7796610169492, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787879, Length=206, Percent_Identity=28.6407766990291, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788297, Length=248, Percent_Identity=28.2258064516129, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788481, Length=298, Percent_Identity=25.503355704698, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1788887, Length=243, Percent_Identity=27.5720164609054, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787601, Length=180, Percent_Identity=28.3333333333333, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787530, Length=257, Percent_Identity=25.2918287937743, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788296, Length=246, Percent_Identity=26.8292682926829, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI2367136, Length=293, Percent_Identity=26.2798634812287, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788748, Length=293, Percent_Identity=22.5255972696246, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI87082132, Length=251, Percent_Identity=24.3027888446215, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790262, Length=253, Percent_Identity=24.5059288537549, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34445; Mature: 34445

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLRKIDRVDMDIRQLKYLDALITAGSFTKAAERLNMAQPALSQSIKRLEQELGVTLVDR
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEC
GANKSSKTLSLTAEGSALHQHAKLIIKNMAQAEAHIKSMANLTMGEVRVAVPGMLGSFYL
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEECCHHHHHHHH
PRRLMAFRHRHPELKLSLFEGGTRDTLKMLQNEDVDIAIITANDLTDEFDSHLLLQEQMV
HHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHH
VAVGREHPLAKSDAVTLEEFFQHELVFFKPGYFHREWMLEQAEQLGLTANIAFETNLINL
HHHCCCCCCCCCCCHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCEEEEEEHHHHHHH
IKQVVAQEYGITTVLEMVIEKHDNICAKPFIPPIFLDLHIAWKKQRPISQADRAFVEFLM
HHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHH
LNR
CCC
>Mature Secondary Structure
MQLRKIDRVDMDIRQLKYLDALITAGSFTKAAERLNMAQPALSQSIKRLEQELGVTLVDR
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEC
GANKSSKTLSLTAEGSALHQHAKLIIKNMAQAEAHIKSMANLTMGEVRVAVPGMLGSFYL
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEECCHHHHHHHH
PRRLMAFRHRHPELKLSLFEGGTRDTLKMLQNEDVDIAIITANDLTDEFDSHLLLQEQMV
HHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHH
VAVGREHPLAKSDAVTLEEFFQHELVFFKPGYFHREWMLEQAEQLGLTANIAFETNLINL
HHHCCCCCCCCCCCHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCEEEEEEHHHHHHH
IKQVVAQEYGITTVLEMVIEKHDNICAKPFIPPIFLDLHIAWKKQRPISQADRAFVEFLM
HHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHH
LNR
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]