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The map label for this gene is oadA [H]

Identifier: 167623170

GI number: 167623170

Start: 1505086

End: 1506897

Strand: Direct

Name: oadA [H]

Synonym: Shal_1236

Alternate gene names: 167623170

Gene position: 1505086-1506897 (Clockwise)

Preceding gene: 167623169

Following gene: 167623171

Centisome position: 28.79

GC content: 48.01

Gene sequence:

>1812_bases
ATGAGCAAGCCACTGGCTTTAACTGATGTTGCGTTAAGAGATGCACATCAATCCATTCTCGCTACTCGTTTGCGTACCGA
AGATATGTTACCCATAGCACCATTACTCGATAAAGTGGGCTTTTGGTCGTTAGAATCATGGGGAGGAGCCACATTTGACT
CCTGTATTCGCTATCTGGGTGAAGATCCTTGGGAGCGGATCCGTGAACTAAAGAAAGTTATGCCTAATACTCCACAGCAG
ATGCTGTTGCGAGGACAAAACCTCCTCGGTTACCGTCACTATGCTGATGACTTGGTACACCGCTTTGTTGAGCGAGCCCA
TACCAATGGTGTTGATGTATTCCGTGTATTCGATGCGATGAACGATGTGCGCAACCTAGAAACAGCGGTTAAAGCGGTTG
TCGAAGTAGGCGGTCATGCCCAAGGCACAATCTCTTATACTACTAGTCCAGTGCATAACTTAAACACTTGGATTGATATG
GCAAAACGTATTGAAGATATGGGTTGTCACTCTTTATGCATTAAAGATATGGCAGGGCTATTAAAGCCGTTTGAAGCATT
TGAGCTTATTAGCCAAATCAAGTCGCAAACCGATTTGGTTTTATCTCTGCACTGCCACGCGACTACAGGCCTGAGCACGG
CAACCTACCAAAAAGCCATTGAAGCGGGCATCGATGTGCTCGATACGGCAATCTCTTCAATGAGCCAGACCTACGGTCAC
AGCGCAACTGAAACTTTAGTTGCTATGGTTGAAGGTACAGACAGGGCAACGGGTTACGATATGGCCCTGCTTGAGGAAAT
TGCGGCCTATTTTAGAACAGTACGTAAAAAGTACGCAGCGTTTGAAGGTGAGTTAAAGGGTATCGATTCACGAATTCTTC
GCGCTCAAGTACCAGGTGGAATGCTAACAAACATGGAAAGCCAGCTTAAAGAGCAGGGCGCCGCTGACAAGTTAGATCTT
GTACTCGAGGAGATCCCTCGCGTTCGTGAAGACTTGGGCTTCTTACCATTGGTGACACCAACGTCGCAAATCGTTGGTAC
ACAGTCTGTGATTAACGTACTCACTGGCGAGCGTTACAAGTCGCTAACCAAAGAAACCGAAGGCGTGTTAAAAGGTGAGT
ATGGTGCAACGCCAGCGCCAGTAAATACGGAGTTACAACAGCGCGTATTAGCGGGGCGTGAAGCCATCACCTGTCGCCCA
GCAGACCTGCTTGAATCTGAGTTAGACAAATTACGTCTGGAGTTAAAAGAGAAAGCCGCTGCCGATGGTATTGCACTTGC
TCAAGAGCTAGATGATGACGTACTCACTTATGCGTTATTTCCGCAAATTGGTCTCAAATTCCTTAGCAACCGTAATAACC
CCGATGCGTTTGAGCCAAAGCCTGAAGTGGCGGCTAAAGCGCTAGAGGAAGCCAAAAAGGCTGAGATTGCCGCTGCAAGT
AAGCAAGGCCCTGAAACATACACTGTTACCGTGCAGGGGCAGAGCTTTGTGGTGGAAGTTGCCGAAGGTGGTGATATCAG
TCAGATCACACCCGCTGAAAACGTGGTGCCTTTTACTGCTCCAACACAGGCTGCAGCAGTGGTGGATCTATCAGCGGTAA
AGCATGAGCAAAACGCGCCTCTATCAGGCAACATCTTTAAAGTGCATGTCTCGCCTGGTGATAGTGTAAAAGAGGGCGAC
GTGGTAATTATCCTCGAAGCGATGAAGATGGAAACAGAAGTGCGCGCCGAAGCTGATGGTGTGATCTCGAAGGTTTGGGT
TAAAGAAGGTGACGCTGTATCGGTTGGTAGCCAATTGTTGGCATTAGCCTAG

Upstream 100 bases:

>100_bases
ACCGAGTCAATCTGCCGTGAGCCCATTAATGGCGGCGGTTATTACTGCTGCAATTCATCAGCACCGAAAAAAAAATATAA
TATAAGTAGGGAGTTTTTGT

Downstream 100 bases:

>100_bases
GGATCACCATGGAAGGATTAATTGCGTTTTGGTCTGAGTCTGGTATTGCTAATTTTACCTCAGGCCAATTGTTGATGATG
GGTGTTGGTTGCCTATTGTT

Product: oxaloacetate decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 603; Mature: 602

Protein sequence:

>603_residues
MSKPLALTDVALRDAHQSILATRLRTEDMLPIAPLLDKVGFWSLESWGGATFDSCIRYLGEDPWERIRELKKVMPNTPQQ
MLLRGQNLLGYRHYADDLVHRFVERAHTNGVDVFRVFDAMNDVRNLETAVKAVVEVGGHAQGTISYTTSPVHNLNTWIDM
AKRIEDMGCHSLCIKDMAGLLKPFEAFELISQIKSQTDLVLSLHCHATTGLSTATYQKAIEAGIDVLDTAISSMSQTYGH
SATETLVAMVEGTDRATGYDMALLEEIAAYFRTVRKKYAAFEGELKGIDSRILRAQVPGGMLTNMESQLKEQGAADKLDL
VLEEIPRVREDLGFLPLVTPTSQIVGTQSVINVLTGERYKSLTKETEGVLKGEYGATPAPVNTELQQRVLAGREAITCRP
ADLLESELDKLRLELKEKAAADGIALAQELDDDVLTYALFPQIGLKFLSNRNNPDAFEPKPEVAAKALEEAKKAEIAAAS
KQGPETYTVTVQGQSFVVEVAEGGDISQITPAENVVPFTAPTQAAAVVDLSAVKHEQNAPLSGNIFKVHVSPGDSVKEGD
VVIILEAMKMETEVRAEADGVISKVWVKEGDAVSVGSQLLALA

Sequences:

>Translated_603_residues
MSKPLALTDVALRDAHQSILATRLRTEDMLPIAPLLDKVGFWSLESWGGATFDSCIRYLGEDPWERIRELKKVMPNTPQQ
MLLRGQNLLGYRHYADDLVHRFVERAHTNGVDVFRVFDAMNDVRNLETAVKAVVEVGGHAQGTISYTTSPVHNLNTWIDM
AKRIEDMGCHSLCIKDMAGLLKPFEAFELISQIKSQTDLVLSLHCHATTGLSTATYQKAIEAGIDVLDTAISSMSQTYGH
SATETLVAMVEGTDRATGYDMALLEEIAAYFRTVRKKYAAFEGELKGIDSRILRAQVPGGMLTNMESQLKEQGAADKLDL
VLEEIPRVREDLGFLPLVTPTSQIVGTQSVINVLTGERYKSLTKETEGVLKGEYGATPAPVNTELQQRVLAGREAITCRP
ADLLESELDKLRLELKEKAAADGIALAQELDDDVLTYALFPQIGLKFLSNRNNPDAFEPKPEVAAKALEEAKKAEIAAAS
KQGPETYTVTVQGQSFVVEVAEGGDISQITPAENVVPFTAPTQAAAVVDLSAVKHEQNAPLSGNIFKVHVSPGDSVKEGD
VVIILEAMKMETEVRAEADGVISKVWVKEGDAVSVGSQLLALA
>Mature_602_residues
SKPLALTDVALRDAHQSILATRLRTEDMLPIAPLLDKVGFWSLESWGGATFDSCIRYLGEDPWERIRELKKVMPNTPQQM
LLRGQNLLGYRHYADDLVHRFVERAHTNGVDVFRVFDAMNDVRNLETAVKAVVEVGGHAQGTISYTTSPVHNLNTWIDMA
KRIEDMGCHSLCIKDMAGLLKPFEAFELISQIKSQTDLVLSLHCHATTGLSTATYQKAIEAGIDVLDTAISSMSQTYGHS
ATETLVAMVEGTDRATGYDMALLEEIAAYFRTVRKKYAAFEGELKGIDSRILRAQVPGGMLTNMESQLKEQGAADKLDLV
LEEIPRVREDLGFLPLVTPTSQIVGTQSVINVLTGERYKSLTKETEGVLKGEYGATPAPVNTELQQRVLAGREAITCRPA
DLLESELDKLRLELKEKAAADGIALAQELDDDVLTYALFPQIGLKFLSNRNNPDAFEPKPEVAAKALEEAKKAEIAAASK
QGPETYTVTVQGQSFVVEVAEGGDISQITPAENVVPFTAPTQAAAVVDLSAVKHEQNAPLSGNIFKVHVSPGDSVKEGDV
VIILEAMKMETEVRAEADGVISKVWVKEGDAVSVGSQLLALA

Specific function: Lyase and sodium transporter [H]

COG id: COG5016

COG function: function code C; Pyruvate/oxaloacetate carboxyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=634, Percent_Identity=32.1766561514196, Blast_Score=279, Evalue=6e-75,
Organism=Homo sapiens, GI106049295, Length=634, Percent_Identity=32.1766561514196, Blast_Score=279, Evalue=6e-75,
Organism=Homo sapiens, GI106049292, Length=634, Percent_Identity=32.1766561514196, Blast_Score=279, Evalue=6e-75,
Organism=Caenorhabditis elegans, GI17562816, Length=631, Percent_Identity=31.5372424722662, Blast_Score=304, Evalue=8e-83,
Organism=Saccharomyces cerevisiae, GI6319695, Length=634, Percent_Identity=33.596214511041, Blast_Score=323, Evalue=4e-89,
Organism=Saccharomyces cerevisiae, GI6321376, Length=634, Percent_Identity=33.4384858044164, Blast_Score=315, Evalue=2e-86,
Organism=Drosophila melanogaster, GI24652212, Length=627, Percent_Identity=33.1738437001595, Blast_Score=306, Evalue=3e-83,
Organism=Drosophila melanogaster, GI24652210, Length=627, Percent_Identity=33.1738437001595, Blast_Score=306, Evalue=3e-83,
Organism=Drosophila melanogaster, GI24652214, Length=627, Percent_Identity=33.1738437001595, Blast_Score=306, Evalue=3e-83,
Organism=Drosophila melanogaster, GI19921944, Length=627, Percent_Identity=33.1738437001595, Blast_Score=306, Evalue=3e-83,
Organism=Drosophila melanogaster, GI24652216, Length=627, Percent_Identity=33.1738437001595, Blast_Score=306, Evalue=3e-83,
Organism=Drosophila melanogaster, GI281363050, Length=627, Percent_Identity=33.1738437001595, Blast_Score=306, Evalue=4e-83,
Organism=Drosophila melanogaster, GI24652224, Length=627, Percent_Identity=33.1738437001595, Blast_Score=306, Evalue=4e-83,
Organism=Drosophila melanogaster, GI24652222, Length=627, Percent_Identity=33.1738437001595, Blast_Score=306, Evalue=4e-83,
Organism=Drosophila melanogaster, GI24652220, Length=627, Percent_Identity=33.1738437001595, Blast_Score=306, Evalue=4e-83,
Organism=Drosophila melanogaster, GI24652218, Length=627, Percent_Identity=33.1738437001595, Blast_Score=306, Evalue=4e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR003379
- InterPro:   IPR005776
- InterPro:   IPR000891
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =4.1.1.3 [H]

Molecular weight: Translated: 65715; Mature: 65583

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPLALTDVALRDAHQSILATRLRTEDMLPIAPLLDKVGFWSLESWGGATFDSCIRYLG
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHC
EDPWERIRELKKVMPNTPQQMLLRGQNLLGYRHYADDLVHRFVERAHTNGVDVFRVFDAM
CCHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
NDVRNLETAVKAVVEVGGHAQGTISYTTSPVHNLNTWIDMAKRIEDMGCHSLCIKDMAGL
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LKPFEAFELISQIKSQTDLVLSLHCHATTGLSTATYQKAIEAGIDVLDTAISSMSQTYGH
HCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SATETLVAMVEGTDRATGYDMALLEEIAAYFRTVRKKYAAFEGELKGIDSRILRAQVPGG
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCHHHHHHHHCCCCC
MLTNMESQLKEQGAADKLDLVLEEIPRVREDLGFLPLVTPTSQIVGTQSVINVLTGERYK
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
SLTKETEGVLKGEYGATPAPVNTELQQRVLAGREAITCRPADLLESELDKLRLELKEKAA
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHH
ADGIALAQELDDDVLTYALFPQIGLKFLSNRNNPDAFEPKPEVAAKALEEAKKAEIAAAS
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
KQGPETYTVTVQGQSFVVEVAEGGDISQITPAENVVPFTAPTQAAAVVDLSAVKHEQNAP
CCCCCEEEEEEECCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
LSGNIFKVHVSPGDSVKEGDVVIILEAMKMETEVRAEADGVISKVWVKEGDAVSVGSQLL
CCCCEEEEEECCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ALA
HCC
>Mature Secondary Structure 
SKPLALTDVALRDAHQSILATRLRTEDMLPIAPLLDKVGFWSLESWGGATFDSCIRYLG
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHC
EDPWERIRELKKVMPNTPQQMLLRGQNLLGYRHYADDLVHRFVERAHTNGVDVFRVFDAM
CCHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
NDVRNLETAVKAVVEVGGHAQGTISYTTSPVHNLNTWIDMAKRIEDMGCHSLCIKDMAGL
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LKPFEAFELISQIKSQTDLVLSLHCHATTGLSTATYQKAIEAGIDVLDTAISSMSQTYGH
HCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SATETLVAMVEGTDRATGYDMALLEEIAAYFRTVRKKYAAFEGELKGIDSRILRAQVPGG
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCHHHHHHHHCCCCC
MLTNMESQLKEQGAADKLDLVLEEIPRVREDLGFLPLVTPTSQIVGTQSVINVLTGERYK
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
SLTKETEGVLKGEYGATPAPVNTELQQRVLAGREAITCRPADLLESELDKLRLELKEKAA
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHH
ADGIALAQELDDDVLTYALFPQIGLKFLSNRNNPDAFEPKPEVAAKALEEAKKAEIAAAS
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
KQGPETYTVTVQGQSFVVEVAEGGDISQITPAENVVPFTAPTQAAAVVDLSAVKHEQNAP
CCCCCEEEEEEECCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
LSGNIFKVHVSPGDSVKEGDVVIILEAMKMETEVRAEADGVISKVWVKEGDAVSVGSQLL
CCCCEEEEEECCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ALA
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2454915 [H]