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The map label for this gene is yiaY [H]

Identifier: 167623130

GI number: 167623130

Start: 1451576

End: 1452724

Strand: Reverse

Name: yiaY [H]

Synonym: Shal_1196

Alternate gene names: 167623130

Gene position: 1452724-1451576 (Counterclockwise)

Preceding gene: 167623131

Following gene: 167623127

Centisome position: 27.79

GC content: 46.21

Gene sequence:

>1149_bases
ATGGCTGCTAAATTTTTCATCCCATCTGTCAATATCTTAGGGCAAGACGCCGTTACTGAAGCGATTGGCGATATCAAGTC
ACTCGGCTTTAAAAATGCATTAATTGTTACAGACAAACCTCTGGTTGATATTGGTCTAGTTGCCCAAGTCACTGACAAGT
TGGCGAGTAACAATATTAACGCTGTGATCTTCGATGGTGTTCAACCTAACCCGACAGTTGGTAACGTCGAAGCGGGTCTT
AAAATTTTAACCGCTAACAACTGTGACTTTGTGATCTCTTTAGGTGGCGGCTCACCTCATGACTGCGCTAAAGGTATTGC
ACTGGTGGCAACCAACGGCGGTAGTATTAAAGATTATGAAGGCCTAGATGTTTCAACTAAGCCACAACTTCCACTCGTTG
CAATTAATACCACCGCTGGTACTGCGAGTGAAATGACACGCTTCTGCATCATTACCGATGAAGAGCGTCATATCAAGATG
GCGATTGTAGACAAGAACACCACACCAATTCTGTCTGTTAACGATCCTGAACTCATGCTCCTCAAGCCTGCTGGTCTAAC
AGCAGCAACGGGGATGGATGCACTGACTCACGCTATCGAAGCGTATGTGTCTATCGCTGCGAACCCTATTACAGATGCCT
GCGCCATTAAAGCTATCGAGCTTATCAAGGCTAACTTAGTTGAGGCCGTTGAAAATGGCCAAAGCATTGAAGCACGCGAT
CAGATGGCTTATGCCCAATTCCTTGCAGGTATGGCATTTAATAACGCCAGCCTTGGCTATGTGCATGCAATGGCACACCA
GCTAGGCGGCTTCTACGACCTACCCCACGGTGTGTGTAACGCACTGCTACTGCCACATGTTCAAGCTTACAACGCACAAG
TAGTACCAAGCCGTCTAAAAGATGTGGCTAAGGCTATGGGTGTCGATGTGTCAGCCATGACTGACGAGCAAGGTGCAGAT
GCTGCAATTACCGCGATTAAAGCACTATCTGTAGCAGTAAAAATTCCAGAAAACCTCACCCAATTAGGTGTGAAGGCTGA
AGATATTCCGACACTTGCTGACAACGCACTTAAAGATGCTTGTGGTTTCACCAACCCTAAGCAGGCGACTCATGAAGAGA
TTTGCCAAATCTTTACTAACGCACTTTAA

Upstream 100 bases:

>100_bases
CGATTATTAGAGCGAGATCACACCTTTATCCCATTAGTGTTGGTACTTTCATTACCAGAAAAGATAACAACTTTTAACAT
TAAGCGTATAGGTGATTCTT

Downstream 100 bases:

>100_bases
TTCAGAGGCACTTTAATCCAGAGGCTCTATTAACTGAGCAACAGGTGACGGTAGCAGGCAATTTTTGCTCCCAGCAATTA
GCTTGCTATCGCCCACTTCT

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MAAKFFIPSVNILGQDAVTEAIGDIKSLGFKNALIVTDKPLVDIGLVAQVTDKLASNNINAVIFDGVQPNPTVGNVEAGL
KILTANNCDFVISLGGGSPHDCAKGIALVATNGGSIKDYEGLDVSTKPQLPLVAINTTAGTASEMTRFCIITDEERHIKM
AIVDKNTTPILSVNDPELMLLKPAGLTAATGMDALTHAIEAYVSIAANPITDACAIKAIELIKANLVEAVENGQSIEARD
QMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNALLLPHVQAYNAQVVPSRLKDVAKAMGVDVSAMTDEQGAD
AAITAIKALSVAVKIPENLTQLGVKAEDIPTLADNALKDACGFTNPKQATHEEICQIFTNAL

Sequences:

>Translated_382_residues
MAAKFFIPSVNILGQDAVTEAIGDIKSLGFKNALIVTDKPLVDIGLVAQVTDKLASNNINAVIFDGVQPNPTVGNVEAGL
KILTANNCDFVISLGGGSPHDCAKGIALVATNGGSIKDYEGLDVSTKPQLPLVAINTTAGTASEMTRFCIITDEERHIKM
AIVDKNTTPILSVNDPELMLLKPAGLTAATGMDALTHAIEAYVSIAANPITDACAIKAIELIKANLVEAVENGQSIEARD
QMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNALLLPHVQAYNAQVVPSRLKDVAKAMGVDVSAMTDEQGAD
AAITAIKALSVAVKIPENLTQLGVKAEDIPTLADNALKDACGFTNPKQATHEEICQIFTNAL
>Mature_381_residues
AAKFFIPSVNILGQDAVTEAIGDIKSLGFKNALIVTDKPLVDIGLVAQVTDKLASNNINAVIFDGVQPNPTVGNVEAGLK
ILTANNCDFVISLGGGSPHDCAKGIALVATNGGSIKDYEGLDVSTKPQLPLVAINTTAGTASEMTRFCIITDEERHIKMA
IVDKNTTPILSVNDPELMLLKPAGLTAATGMDALTHAIEAYVSIAANPITDACAIKAIELIKANLVEAVENGQSIEARDQ
MAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNALLLPHVQAYNAQVVPSRLKDVAKAMGVDVSAMTDEQGADA
AITAIKALSVAVKIPENLTQLGVKAEDIPTLADNALKDACGFTNPKQATHEEICQIFTNAL

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=413, Percent_Identity=28.0871670702179, Blast_Score=141, Evalue=1e-33,
Organism=Escherichia coli, GI48994951, Length=381, Percent_Identity=67.4540682414698, Blast_Score=528, Evalue=1e-151,
Organism=Escherichia coli, GI1789163, Length=384, Percent_Identity=44.0104166666667, Blast_Score=323, Evalue=9e-90,
Organism=Escherichia coli, GI87082107, Length=377, Percent_Identity=35.5437665782493, Blast_Score=214, Evalue=9e-57,
Organism=Escherichia coli, GI1787493, Length=393, Percent_Identity=31.8066157760814, Blast_Score=185, Evalue=5e-48,
Organism=Escherichia coli, GI1789386, Length=319, Percent_Identity=25.0783699059561, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17537053, Length=406, Percent_Identity=25.3694581280788, Blast_Score=117, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6321181, Length=379, Percent_Identity=54.6174142480211, Blast_Score=411, Evalue=1e-115,
Organism=Drosophila melanogaster, GI24657991, Length=410, Percent_Identity=27.0731707317073, Blast_Score=146, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 40001; Mature: 39870

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAKFFIPSVNILGQDAVTEAIGDIKSLGFKNALIVTDKPLVDIGLVAQVTDKLASNNIN
CCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCC
AVIFDGVQPNPTVGNVEAGLKILTANNCDFVISLGGGSPHDCAKGIALVATNGGSIKDYE
EEEECCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCHHHCCEEEEEECCCCCCCCC
GLDVSTKPQLPLVAINTTAGTASEMTRFCIITDEERHIKMAIVDKNTTPILSVNDPELML
CCCCCCCCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEEEEEECCCCEEEEECCCCEEE
LKPAGLTAATGMDALTHAIEAYVSIAANPITDACAIKAIELIKANLVEAVENGQSIEARD
ECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
QMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNALLLPHVQAYNAQVVPSRLK
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHCCCEECHHHHH
DVAKAMGVDVSAMTDEQGADAAITAIKALSVAVKIPENLTQLGVKAEDIPTLADNALKDA
HHHHHHCCCEEECCCCCCCCHHHHHHHHHHHEEECCHHHHHHCCCCCCCCHHHHHHHHHH
CGFTNPKQATHEEICQIFTNAL
CCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AAKFFIPSVNILGQDAVTEAIGDIKSLGFKNALIVTDKPLVDIGLVAQVTDKLASNNIN
CCEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCC
AVIFDGVQPNPTVGNVEAGLKILTANNCDFVISLGGGSPHDCAKGIALVATNGGSIKDYE
EEEECCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCHHHCCEEEEEECCCCCCCCC
GLDVSTKPQLPLVAINTTAGTASEMTRFCIITDEERHIKMAIVDKNTTPILSVNDPELML
CCCCCCCCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEEEEEECCCCEEEEECCCCEEE
LKPAGLTAATGMDALTHAIEAYVSIAANPITDACAIKAIELIKANLVEAVENGQSIEARD
ECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
QMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNALLLPHVQAYNAQVVPSRLK
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHCCCEECHHHHH
DVAKAMGVDVSAMTDEQGADAAITAIKALSVAVKIPENLTQLGVKAEDIPTLADNALKDA
HHHHHHCCCEEECCCCCCCCHHHHHHHHHHHEEECCHHHHHHCCCCCCCCHHHHHHHHHH
CGFTNPKQATHEEICQIFTNAL
CCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]