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The map label for this gene is ndh [H]

Identifier: 167623125

GI number: 167623125

Start: 1444034

End: 1445335

Strand: Reverse

Name: ndh [H]

Synonym: Shal_1191

Alternate gene names: 167623125

Gene position: 1445335-1444034 (Counterclockwise)

Preceding gene: 167623126

Following gene: 167623123

Centisome position: 27.65

GC content: 46.54

Gene sequence:

>1302_bases
ATGCATGAAATGGCCAATATTGTCATCGTTGGTGGTGGCGCAGGTGGAATGGAGATAGCAACAAAGCTCGGTCACCAATT
AGGGCGTAAAGGCAAAGCCAGGGTCACCTTAATTGACTGCGCCGAGAGCCATATTTGGAAACCACTACTGCATGAGGTTG
CTACTGGAGCACTAGACATTGGTATCGATGCGATCAGCTATCGCGGTCATGCCGCAAGCCATGGTTACCATTTCCAGCAA
GGTGCGATGACTGATATCGATAGAGAAGCTAAGCAAGTTATTTTAGCGCCAATTAACGATGATAAAGGTCGTGAATTACT
CCCTGCACGCCGCATCGATTATGACTACTTAGTTATTGCCATTGGTAGTATCGCCAATGACTTTAATATTACTGGCGTAC
GTGAGCACTGTGTATTTTTAGATAGCACCGAACAGGCGATGGAAATTCGCACCATGCTACTGAATAAATTCATGCGCTAT
GCTAGCCACCATCAGCTCGATGATAAAATCAAAATTGCCGTCGTGGGTGCAGGTGCAACCGGTGTCGAGATGTCGGCTGA
GATGCACCATGCGGTCGAACAACTACGCGGCTTCGGTTATAAAATCGATAGCAGTCTATTGGAAATAACCCTTATCGAAG
CCGATGAACGCATTCTTCCGAAGGTCGAGAAAGAGGAGATCTCGGCCTCTGTCGCTAAGGAGTTAACCTCTATTGGCGTG
AAAGTGATGACCAGCACGCGTATTAATCAAGTCACAGAAGAAGGCCTACACACCTCTGAAGGCGAATTTATTCAGTCAGA
TATGGTGATCTGGTCGACAGGTGTTAAAGCTCCTGACTTCTTAAAAGAGATCGGCGGCCTTGAGAGTAACCATATCAATC
AGGTAATGGTACAACAAAATATGCAGACCACCCGCGATCCAGCCATTTTAGCTATCGGTGACTGCGCAGCGTGCCCACAA
GAAGATGGTAGCTGGGTTCCACCACGCGGCCAATCTGCACGCCAGATGGCATTAATGACTGCTGATAATATTAAGTTATT
GCTAGCAGGAAAACCCGCCTCAAACAATTATGTCTATAAAGATTTAGGCGCCTTGGTCAATTTATCAAAATTCCACACGG
TCGGTAATCTCATGTCATTCATCGGTGGTGGCATAATGGTCGAAGGTAAGATTGCTCGCTTCGTCTATACCTCACTCTAT
AGAAGACACCTTATCGAGCTACACGGCCCAATTAAAGGCACCCTGCTTATGTTTGCCAAAGGGATCAGTCGAATCGTACA
CCCACATTTGAAGCTACACTAA

Upstream 100 bases:

>100_bases
CAATTGATGACCAGAGTGAAATTAACTGTGTTTGAGCGTCACAACAGGCTAATACCTATATTTATTTTACAGTTTTATCG
ACTTAAGGATTATAAAGCTC

Downstream 100 bases:

>100_bases
TAAGCTTTGTGAATGTTGCTGGTAGTCTGGTTTAGCACCAGCAACATTTTCTGCCAAATTGAGTTGGCTTGCTCAGTTTT
CCTAAACTTTAAACAAAAGT

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MHEMANIVIVGGGAGGMEIATKLGHQLGRKGKARVTLIDCAESHIWKPLLHEVATGALDIGIDAISYRGHAASHGYHFQQ
GAMTDIDREAKQVILAPINDDKGRELLPARRIDYDYLVIAIGSIANDFNITGVREHCVFLDSTEQAMEIRTMLLNKFMRY
ASHHQLDDKIKIAVVGAGATGVEMSAEMHHAVEQLRGFGYKIDSSLLEITLIEADERILPKVEKEEISASVAKELTSIGV
KVMTSTRINQVTEEGLHTSEGEFIQSDMVIWSTGVKAPDFLKEIGGLESNHINQVMVQQNMQTTRDPAILAIGDCAACPQ
EDGSWVPPRGQSARQMALMTADNIKLLLAGKPASNNYVYKDLGALVNLSKFHTVGNLMSFIGGGIMVEGKIARFVYTSLY
RRHLIELHGPIKGTLLMFAKGISRIVHPHLKLH

Sequences:

>Translated_433_residues
MHEMANIVIVGGGAGGMEIATKLGHQLGRKGKARVTLIDCAESHIWKPLLHEVATGALDIGIDAISYRGHAASHGYHFQQ
GAMTDIDREAKQVILAPINDDKGRELLPARRIDYDYLVIAIGSIANDFNITGVREHCVFLDSTEQAMEIRTMLLNKFMRY
ASHHQLDDKIKIAVVGAGATGVEMSAEMHHAVEQLRGFGYKIDSSLLEITLIEADERILPKVEKEEISASVAKELTSIGV
KVMTSTRINQVTEEGLHTSEGEFIQSDMVIWSTGVKAPDFLKEIGGLESNHINQVMVQQNMQTTRDPAILAIGDCAACPQ
EDGSWVPPRGQSARQMALMTADNIKLLLAGKPASNNYVYKDLGALVNLSKFHTVGNLMSFIGGGIMVEGKIARFVYTSLY
RRHLIELHGPIKGTLLMFAKGISRIVHPHLKLH
>Mature_433_residues
MHEMANIVIVGGGAGGMEIATKLGHQLGRKGKARVTLIDCAESHIWKPLLHEVATGALDIGIDAISYRGHAASHGYHFQQ
GAMTDIDREAKQVILAPINDDKGRELLPARRIDYDYLVIAIGSIANDFNITGVREHCVFLDSTEQAMEIRTMLLNKFMRY
ASHHQLDDKIKIAVVGAGATGVEMSAEMHHAVEQLRGFGYKIDSSLLEITLIEADERILPKVEKEEISASVAKELTSIGV
KVMTSTRINQVTEEGLHTSEGEFIQSDMVIWSTGVKAPDFLKEIGGLESNHINQVMVQQNMQTTRDPAILAIGDCAACPQ
EDGSWVPPRGQSARQMALMTADNIKLLLAGKPASNNYVYKDLGALVNLSKFHTVGNLMSFIGGGIMVEGKIARFVYTSLY
RRHLIELHGPIKGTLLMFAKGISRIVHPHLKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=432, Percent_Identity=54.8611111111111, Blast_Score=484, Evalue=1e-138,
Organism=Saccharomyces cerevisiae, GI6320118, Length=329, Percent_Identity=27.355623100304, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323794, Length=330, Percent_Identity=26.3636363636364, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323515, Length=457, Percent_Identity=26.0393873085339, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 47488; Mature: 47488

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEMANIVIVGGGAGGMEIATKLGHQLGRKGKARVTLIDCAESHIWKPLLHEVATGALDI
CCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHCCHHHC
GIDAISYRGHAASHGYHFQQGAMTDIDREAKQVILAPINDDKGRELLPARRIDYDYLVIA
CCEEEECCCCCCCCCEEECCCCCCHHCHHCCEEEEEECCCCCCCCCCCHHHCCCCEEEEE
IGSIANDFNITGVREHCVFLDSTEQAMEIRTMLLNKFMRYASHHQLDDKIKIAVVGAGAT
EECCCCCCCCCEEEHEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCC
GVEMSAEMHHAVEQLRGFGYKIDSSLLEITLIEADERILPKVEKEEISASVAKELTSIGV
CCCHHHHHHHHHHHHHCCCEEECCCEEEEEEEECCCHHCCCCCHHHHHHHHHHHHHHCCE
KVMTSTRINQVTEEGLHTSEGEFIQSDMVIWSTGVKAPDFLKEIGGLESNHINQVMVQQN
EEEEHHHHHHHHHHCCCCCCCCEECCCEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHC
MQTTRDPAILAIGDCAACPQEDGSWVPPRGQSARQMALMTADNIKLLLAGKPASNNYVYK
CCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCEEEEEECCCCCCCCCHH
DLGALVNLSKFHTVGNLMSFIGGGIMVEGKIARFVYTSLYRRHLIELHGPIKGTLLMFAK
HHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GISRIVHPHLKLH
HHHHHHCCCCCCC
>Mature Secondary Structure
MHEMANIVIVGGGAGGMEIATKLGHQLGRKGKARVTLIDCAESHIWKPLLHEVATGALDI
CCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHCCHHHC
GIDAISYRGHAASHGYHFQQGAMTDIDREAKQVILAPINDDKGRELLPARRIDYDYLVIA
CCEEEECCCCCCCCCEEECCCCCCHHCHHCCEEEEEECCCCCCCCCCCHHHCCCCEEEEE
IGSIANDFNITGVREHCVFLDSTEQAMEIRTMLLNKFMRYASHHQLDDKIKIAVVGAGAT
EECCCCCCCCCEEEHEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCC
GVEMSAEMHHAVEQLRGFGYKIDSSLLEITLIEADERILPKVEKEEISASVAKELTSIGV
CCCHHHHHHHHHHHHHCCCEEECCCEEEEEEEECCCHHCCCCCHHHHHHHHHHHHHHCCE
KVMTSTRINQVTEEGLHTSEGEFIQSDMVIWSTGVKAPDFLKEIGGLESNHINQVMVQQN
EEEEHHHHHHHHHHCCCCCCCCEECCCEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHC
MQTTRDPAILAIGDCAACPQEDGSWVPPRGQSARQMALMTADNIKLLLAGKPASNNYVYK
CCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCEEEEEECCCCCCCCCHH
DLGALVNLSKFHTVGNLMSFIGGGIMVEGKIARFVYTSLYRRHLIELHGPIKGTLLMFAK
HHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GISRIVHPHLKLH
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]