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The map label for this gene is glsA [H]

Identifier: 167623091

GI number: 167623091

Start: 1407587

End: 1408501

Strand: Direct

Name: glsA [H]

Synonym: Shal_1157

Alternate gene names: 167623091

Gene position: 1407587-1408501 (Clockwise)

Preceding gene: 167623090

Following gene: 167623092

Centisome position: 26.93

GC content: 46.99

Gene sequence:

>915_bases
ATGCCTGAATTGGCATTACTTGAAGAGATCGTCGAAAAAGTACGACCTCTTTTAGGACAGGGTAAAGTGGCTGACTATAT
TCCAGCCCTTGCCCAAGTCGATGCTAATAAGTTAGGTATTGCGGTGACCACCTCTGACGGTGTCACAATAGGGGCTGGAG
ATTATCTCGAGCCCTTTTCAATTCAGAGTATCTCTAAGGTGTTCAGTCTTACCTTGGCACTAATGCTGTATGAAGAAGAT
GAGATTTGGTCACGAGTCGGTAAAGAACCCTCTGGCCACTCTTTTAACTCTTTAGTACAGGTTGAATTAGAAAAAGGCTT
ACCGCGAAATCCTTTTATTAATGCTGGCGCGTTGGTCATTGCCGATCTTCTGCAGAGTCGCCTGGGTGCGCCTAAGCACC
GGATGCTTGAAATTGTTCGGGGTTTAAGTGAAAACCATAGAGTGGGTTACGACAAAGTCGTTGCCGCGTCTGAATATCAA
CACAGTGCGAGAAACGCCGCTATTGCTTACCTGATGAAATCATTTGGTAACTTTAATAACGACGTCAATACTGTGCTACA
CAGCTACTTTCACTATTGCTCACTTCGTATGAGCTGCGCCGATCTATCCCGTGCTATGTTTTATCTGGCTAACTCTGGTA
AAAGCCTCGCAGGTAAGCAACTTATTTCGCCGGTGCAAAATCGGCAGCTAAATGCCTTATTAGCCACATCTGGTCTTTAT
GACGGTGCGGGTGAGTTCGCTTATCGAGTCGGTATGCCGGGTAAGAGCGGTGTCGGTGGCGGCATTATCGCGGTGATCCC
TGGCGATATGTCTGTGTGTGTTTGGTCTCCTGAACTTGATGCCAATGGTAACTCTTTGGCAGGCACTGCAGTGTTAGAGA
CCTTGAGCCAGACTCTAGGCCGGTCTATTTTTTAG

Upstream 100 bases:

>100_bases
AATGTACCGAAGAGAACCGAGCTGCAGTTAAAGCATTCTTCGATGCTCAACCTGTATCTGATCTAGAAATTGGTGAGCTT
TTCGATATCTGGTGGGGCTA

Downstream 100 bases:

>100_bases
TTTTCCTCGCTCTATTATTTATATCTGCATCGATATCAGTACCTACATCAGCGGTTTGTGATATTTGGCCAATTGTTAGT
TTAACTGGCCAAATATATTA

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MPELALLEEIVEKVRPLLGQGKVADYIPALAQVDANKLGIAVTTSDGVTIGAGDYLEPFSIQSISKVFSLTLALMLYEED
EIWSRVGKEPSGHSFNSLVQVELEKGLPRNPFINAGALVIADLLQSRLGAPKHRMLEIVRGLSENHRVGYDKVVAASEYQ
HSARNAAIAYLMKSFGNFNNDVNTVLHSYFHYCSLRMSCADLSRAMFYLANSGKSLAGKQLISPVQNRQLNALLATSGLY
DGAGEFAYRVGMPGKSGVGGGIIAVIPGDMSVCVWSPELDANGNSLAGTAVLETLSQTLGRSIF

Sequences:

>Translated_304_residues
MPELALLEEIVEKVRPLLGQGKVADYIPALAQVDANKLGIAVTTSDGVTIGAGDYLEPFSIQSISKVFSLTLALMLYEED
EIWSRVGKEPSGHSFNSLVQVELEKGLPRNPFINAGALVIADLLQSRLGAPKHRMLEIVRGLSENHRVGYDKVVAASEYQ
HSARNAAIAYLMKSFGNFNNDVNTVLHSYFHYCSLRMSCADLSRAMFYLANSGKSLAGKQLISPVQNRQLNALLATSGLY
DGAGEFAYRVGMPGKSGVGGGIIAVIPGDMSVCVWSPELDANGNSLAGTAVLETLSQTLGRSIF
>Mature_303_residues
PELALLEEIVEKVRPLLGQGKVADYIPALAQVDANKLGIAVTTSDGVTIGAGDYLEPFSIQSISKVFSLTLALMLYEEDE
IWSRVGKEPSGHSFNSLVQVELEKGLPRNPFINAGALVIADLLQSRLGAPKHRMLEIVRGLSENHRVGYDKVVAASEYQH
SARNAAIAYLMKSFGNFNNDVNTVLHSYFHYCSLRMSCADLSRAMFYLANSGKSLAGKQLISPVQNRQLNALLATSGLYD
GAGEFAYRVGMPGKSGVGGGIIAVIPGDMSVCVWSPELDANGNSLAGTAVLETLSQTLGRSIF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=294, Percent_Identity=35.7142857142857, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI20336214, Length=294, Percent_Identity=34.0136054421769, Blast_Score=159, Evalue=2e-39,
Organism=Escherichia coli, GI1787804, Length=301, Percent_Identity=64.4518272425249, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI1786693, Length=289, Percent_Identity=35.9861591695502, Blast_Score=167, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI17507019, Length=294, Percent_Identity=36.734693877551, Blast_Score=178, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17532727, Length=303, Percent_Identity=33.3333333333333, Blast_Score=177, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI193204073, Length=305, Percent_Identity=33.7704918032787, Blast_Score=158, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI193204075, Length=307, Percent_Identity=33.5504885993485, Blast_Score=157, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24653156, Length=285, Percent_Identity=35.7894736842105, Blast_Score=168, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24653158, Length=285, Percent_Identity=35.7894736842105, Blast_Score=168, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24653164, Length=285, Percent_Identity=35.7894736842105, Blast_Score=168, Evalue=5e-42,
Organism=Drosophila melanogaster, GI281363241, Length=285, Percent_Identity=35.7894736842105, Blast_Score=168, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24653166, Length=285, Percent_Identity=35.7894736842105, Blast_Score=168, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24653162, Length=285, Percent_Identity=35.7894736842105, Blast_Score=168, Evalue=5e-42,
Organism=Drosophila melanogaster, GI281363239, Length=285, Percent_Identity=35.7894736842105, Blast_Score=168, Evalue=5e-42,
Organism=Drosophila melanogaster, GI116008307, Length=285, Percent_Identity=35.7894736842105, Blast_Score=167, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 32654; Mature: 32523

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPELALLEEIVEKVRPLLGQGKVADYIPALAQVDANKLGIAVTTSDGVTIGAGDYLEPFS
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCCCCCH
IQSISKVFSLTLALMLYEEDEIWSRVGKEPSGHSFNSLVQVELEKGLPRNPFINAGALVI
HHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCHHHEEEEEHHCCCCCCCCCCCHHHHH
ADLLQSRLGAPKHRMLEIVRGLSENHRVGYDKVVAASEYQHSARNAAIAYLMKSFGNFNN
HHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DVNTVLHSYFHYCSLRMSCADLSRAMFYLANSGKSLAGKQLISPVQNRQLNALLATSGLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHCCCC
DGAGEFAYRVGMPGKSGVGGGIIAVIPGDMSVCVWSPELDANGNSLAGTAVLETLSQTLG
CCCCCCEEEECCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHC
RSIF
CCCC
>Mature Secondary Structure 
PELALLEEIVEKVRPLLGQGKVADYIPALAQVDANKLGIAVTTSDGVTIGAGDYLEPFS
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCCCCCH
IQSISKVFSLTLALMLYEEDEIWSRVGKEPSGHSFNSLVQVELEKGLPRNPFINAGALVI
HHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCHHHEEEEEHHCCCCCCCCCCCHHHHH
ADLLQSRLGAPKHRMLEIVRGLSENHRVGYDKVVAASEYQHSARNAAIAYLMKSFGNFNN
HHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DVNTVLHSYFHYCSLRMSCADLSRAMFYLANSGKSLAGKQLISPVQNRQLNALLATSGLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHCCCC
DGAGEFAYRVGMPGKSGVGGGIIAVIPGDMSVCVWSPELDANGNSLAGTAVLETLSQTLG
CCCCCCEEEECCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHC
RSIF
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA