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The map label for this gene is ribF [H]

Identifier: 167623064

GI number: 167623064

Start: 1372980

End: 1373915

Strand: Direct

Name: ribF [H]

Synonym: Shal_1130

Alternate gene names: 167623064

Gene position: 1372980-1373915 (Clockwise)

Preceding gene: 167623063

Following gene: 167623065

Centisome position: 26.27

GC content: 42.2

Gene sequence:

>936_bases
ATGGAATTAATCCGCGGTATTCATAATATTTTGCCGAAACATCGAGGTTGCGTATTAAGCATAGGCAACTTCGATGGTGT
TCACCGTGGTCATGCGGAAGTGATTAATCGGCTCGTGAAAAAAGCAAAACATTTAGGTTTGCCTGCTGTTGTAATGACTT
TTGAACCACAGCCACGAGAGTTGTTTCAGGGTGAGAATGCGCCAGCTCGTTTGAGTTTGCTACGAGACAAGATAGTCTTG
CTCGATGAGTTAAAGATCGATCGCTTATTATGTGTAAACTTTAATAATAAGTTTTCAAGTTTTACGGCAGAGGATTTTAT
CGAGCTACTACTCGTTAAGGCCCTTGGTGTGAAGTACCTAGTTGTTGGCGACGACTTTTGTTTTGGGAAGCAACGCCAAG
GTAATTTTGAGATGTTACGCAAGGCCGGAGAAAAGCATGGTTTTGCTGTAGTAAGCACTCAGAGTTTTATTCTGGGCGAT
AAGCGAGTTAGCTCTACGGAAGTTAGACAGTTGCTTGCAAAGGGTAACTTAGAGCAAGCAAGACGCTTGTTAGGGCATCC
TTTTACGTTAAGCGGTAAGGTTGCTCATGGTGAAAAAATTGGGAGAACGTTAGGTTTTCCTACCGCTAATATTGCCTTAA
AACGCAAAGTGTCGCCTGTTAGAGGCGTGTTTGCAGTTAAATTATATTGGGATAATAGCGACATATATGAAGGCGTAGCC
AACGTTGGTTTTAGGCCAACGGTAAATGGTCAAGTCTGTCAGTTAGAAGTCCATTTATTTGATTTTGATGGTGACCTTTA
TGGCAAAACTGTCGAAGTTGAATTAGTGGCAAAGATTAGAGACGAGCAGCCATTTGGATCGTTAGATGCGCTGAAAAAAC
AAATTAAAGATGATGCCAATAGAGCGAAAGCCCTACTTGGTAGCGATGCAGGCTGA

Upstream 100 bases:

>100_bases
GAATTCGTCCTTGGAAGATGAAAGCTGCTGTTTGAGTGCTGATTATAAAGCCTAGCTGGTATATAATCCGCCCATTTACT
CTCATGTGTCGTGTAAGATA

Downstream 100 bases:

>100_bases
ACAGCTTAGCTAACAAAACGGTAAAGGATCAATGAGCGACTATAAATCTACTTTGAATTTGCCGGAAACAGAGTTTCCGA
TGCGTGGTAATTTGGCTAAT

Product: riboflavin biosynthesis protein RibF

Products: NA

Alternate protein names: Riboflavin kinase; Flavokinase; FMN adenylyltransferase; FAD pyrophosphorylase; FAD synthase [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MELIRGIHNILPKHRGCVLSIGNFDGVHRGHAEVINRLVKKAKHLGLPAVVMTFEPQPRELFQGENAPARLSLLRDKIVL
LDELKIDRLLCVNFNNKFSSFTAEDFIELLLVKALGVKYLVVGDDFCFGKQRQGNFEMLRKAGEKHGFAVVSTQSFILGD
KRVSSTEVRQLLAKGNLEQARRLLGHPFTLSGKVAHGEKIGRTLGFPTANIALKRKVSPVRGVFAVKLYWDNSDIYEGVA
NVGFRPTVNGQVCQLEVHLFDFDGDLYGKTVEVELVAKIRDEQPFGSLDALKKQIKDDANRAKALLGSDAG

Sequences:

>Translated_311_residues
MELIRGIHNILPKHRGCVLSIGNFDGVHRGHAEVINRLVKKAKHLGLPAVVMTFEPQPRELFQGENAPARLSLLRDKIVL
LDELKIDRLLCVNFNNKFSSFTAEDFIELLLVKALGVKYLVVGDDFCFGKQRQGNFEMLRKAGEKHGFAVVSTQSFILGD
KRVSSTEVRQLLAKGNLEQARRLLGHPFTLSGKVAHGEKIGRTLGFPTANIALKRKVSPVRGVFAVKLYWDNSDIYEGVA
NVGFRPTVNGQVCQLEVHLFDFDGDLYGKTVEVELVAKIRDEQPFGSLDALKKQIKDDANRAKALLGSDAG
>Mature_311_residues
MELIRGIHNILPKHRGCVLSIGNFDGVHRGHAEVINRLVKKAKHLGLPAVVMTFEPQPRELFQGENAPARLSLLRDKIVL
LDELKIDRLLCVNFNNKFSSFTAEDFIELLLVKALGVKYLVVGDDFCFGKQRQGNFEMLRKAGEKHGFAVVSTQSFILGD
KRVSSTEVRQLLAKGNLEQARRLLGHPFTLSGKVAHGEKIGRTLGFPTANIALKRKVSPVRGVFAVKLYWDNSDIYEGVA
NVGFRPTVNGQVCQLEVHLFDFDGDLYGKTVEVELVAKIRDEQPFGSLDALKKQIKDDANRAKALLGSDAG

Specific function: Unknown

COG id: COG0196

COG function: function code H; FAD synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribF family [H]

Homologues:

Organism=Escherichia coli, GI1786208, Length=308, Percent_Identity=53.8961038961039, Blast_Score=325, Evalue=2e-90,
Organism=Drosophila melanogaster, GI24644927, Length=126, Percent_Identity=34.1269841269841, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015864
- InterPro:   IPR015865
- InterPro:   IPR002606
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06574 FAD_syn; PF01687 Flavokinase [H]

EC number: =2.7.1.26; =2.7.7.2 [H]

Molecular weight: Translated: 34529; Mature: 34529

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELIRGIHNILPKHRGCVLSIGNFDGVHRGHAEVINRLVKKAKHLGLPAVVMTFEPQPRE
CHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHH
LFQGENAPARLSLLRDKIVLLDELKIDRLLCVNFNNKFSSFTAEDFIELLLVKALGVKYL
HHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCEEEE
VVGDDFCFGKQRQGNFEMLRKAGEKHGFAVVSTQSFILGDKRVSSTEVRQLLAKGNLEQA
EEECCCCCCCCCCCCHHHHHHCCCCCCEEEEECCEEEECCCCCCHHHHHHHHHCCCHHHH
RRLLGHPFTLSGKVAHGEKIGRTLGFPTANIALKRKVSPVRGVFAVKLYWDNSDIYEGVA
HHHHCCCCEECCCCCCHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEEEECCCHHHHHHH
NVGFRPTVNGQVCQLEVHLFDFDGDLYGKTVEVELVAKIRDEQPFGSLDALKKQIKDDAN
HCCCCCCCCCEEEEEEEEEEECCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHH
RAKALLGSDAG
HHHHHHCCCCC
>Mature Secondary Structure
MELIRGIHNILPKHRGCVLSIGNFDGVHRGHAEVINRLVKKAKHLGLPAVVMTFEPQPRE
CHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHH
LFQGENAPARLSLLRDKIVLLDELKIDRLLCVNFNNKFSSFTAEDFIELLLVKALGVKYL
HHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCEEEE
VVGDDFCFGKQRQGNFEMLRKAGEKHGFAVVSTQSFILGDKRVSSTEVRQLLAKGNLEQA
EEECCCCCCCCCCCCHHHHHHCCCCCCEEEEECCEEEECCCCCCHHHHHHHHHCCCHHHH
RRLLGHPFTLSGKVAHGEKIGRTLGFPTANIALKRKVSPVRGVFAVKLYWDNSDIYEGVA
HHHHCCCCEECCCCCCHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEEEECCCHHHHHHH
NVGFRPTVNGQVCQLEVHLFDFDGDLYGKTVEVELVAKIRDEQPFGSLDALKKQIKDDAN
HCCCCCCCCCEEEEEEEEEEECCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHH
RAKALLGSDAG
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]