Click here to switch to the map view.

The map label for this gene is acpS

Identifier: 167623021

GI number: 167623021

Start: 1325516

End: 1325911

Strand: Direct

Name: acpS

Synonym: Shal_1087

Alternate gene names: 167623021

Gene position: 1325516-1325911 (Clockwise)

Preceding gene: 167623020

Following gene: 167623024

Centisome position: 25.36

GC content: 50.25

Gene sequence:

>396_bases
ATGATCGTTGGTTTAGGCACCGATATTGTTGAAATTGCGCGAATAGAAGCGCGTATTCCTACAGCAGGCGATGAAGCGCT
ATTAAGCTGTCGCTTAGCAAAGCGTGTGTTAACCAAAACCGAATTTGCACTCTTTGTTGCGTCATCTCAACCGGGGCGAT
ATCTGGCTAAACGCTTTGCCGCTAAAGAAGCTGCAGCCAAAGCGTTGGGGACTGGTATAGGCCGTGGTGTTTCATTTCAA
CATATTGAGATCAGTAATAACACCAATGGCGCTCCGTTAGTGGCCTTTAGTGACGGCGCTGCCGAACGCTTGGCTCAGCT
TGGTGGAAGCCGAGCACACCTCTCCATAGCCGATGAGAAACACTACGCAACGGCGACCGTGATCCTAGAGTCTTGA

Upstream 100 bases:

>100_bases
GTTATTTAAGTTTAGTTATTTAATTCTCGAACTTAAAGCCTCGAATTTAAAGTCACTAGGGTTAGAGATTAGGTTGGTTT
TAGCTAAATAGGGGAGTGTT

Downstream 100 bases:

>100_bases
TGCTGCTTTTTATGAGCAGAGACTCATTACCTGCTCACCATTAATGTCTTGCTCGCCAGTAAACTCAAAACCTAGCTTAT
GATATAAAGCGATGGCCGCA

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MIVGLGTDIVEIARIEARIPTAGDEALLSCRLAKRVLTKTEFALFVASSQPGRYLAKRFAAKEAAAKALGTGIGRGVSFQ
HIEISNNTNGAPLVAFSDGAAERLAQLGGSRAHLSIADEKHYATATVILES

Sequences:

>Translated_131_residues
MIVGLGTDIVEIARIEARIPTAGDEALLSCRLAKRVLTKTEFALFVASSQPGRYLAKRFAAKEAAAKALGTGIGRGVSFQ
HIEISNNTNGAPLVAFSDGAAERLAQLGGSRAHLSIADEKHYATATVILES
>Mature_131_residues
MIVGLGTDIVEIARIEARIPTAGDEALLSCRLAKRVLTKTEFALFVASSQPGRYLAKRFAAKEAAAKALGTGIGRGVSFQ
HIEISNNTNGAPLVAFSDGAAERLAQLGGSRAHLSIADEKHYATATVILES

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=130, Percent_Identity=52.3076923076923, Blast_Score=128, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_SHEHH (B0TIW1)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001673315.1
- ProteinModelPortal:   B0TIW1
- SMR:   B0TIW1
- GeneID:   5904907
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_1087
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- ProtClustDB:   PRK00070
- BioCyc:   SHAL458817:SHAL_1087-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 13750; Mature: 13750

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVGLGTDIVEIARIEARIPTAGDEALLSCRLAKRVLTKTEFALFVASSQPGRYLAKRFA
CEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHH
AKEAAAKALGTGIGRGVSFQHIEISNNTNGAPLVAFSDGAAERLAQLGGSRAHLSIADEK
HHHHHHHHHHCCCCCCCEEEEEEECCCCCCCEEEEECCCHHHHHHHCCCCEEEEEECCCC
HYATATVILES
CEEEEEEEEEC
>Mature Secondary Structure
MIVGLGTDIVEIARIEARIPTAGDEALLSCRLAKRVLTKTEFALFVASSQPGRYLAKRFA
CEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHH
AKEAAAKALGTGIGRGVSFQHIEISNNTNGAPLVAFSDGAAERLAQLGGSRAHLSIADEK
HHHHHHHHHHCCCCCCCEEEEEEECCCCCCCEEEEECCCHHHHHHHCCCCEEEEEECCCC
HYATATVILES
CEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA