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The map label for this gene is apbE [H]

Identifier: 167622962

GI number: 167622962

Start: 1256015

End: 1256941

Strand: Reverse

Name: apbE [H]

Synonym: Shal_1026

Alternate gene names: 167622962

Gene position: 1256941-1256015 (Counterclockwise)

Preceding gene: 167622964

Following gene: 167622961

Centisome position: 24.05

GC content: 35.06

Gene sequence:

>927_bases
ATGGGCAATAGTTATAACATCAAGTGGAAGGAGAAAAAAATATCCGCTAATAGAATGCACCATATAAATACAAAGGTAAA
AGCAAAGTTAACAGAATTAAATGAGACCATGTCGAGCTGGGATAACAACTCAGAGTTAAGCTTATTAAACAACTCCAAAG
AAAAGCAGTTCAACATAAGCCCAGATCTCGAGTATGTAATAAGCGAGGCTATCAGAATTCATCATGTTACTCATGGAGCA
TTAGATATAACGGTTGATCCATTAATTAGTTTATGGGGCTTCGGTGCAACTGATCGAGAATATAACGTTCCTAGTCATAC
AGATATAAGTAAAACATTAAAATTTGTCGGCATGGATAAGATTAACGTTGCAGATGGTGCTCTAACTCGGACTTCTACAA
AAGTGACCTTAAACTTATCATCTATAGCAAAAGGCTTTGCGGTGGATGCCGTAACCATCATTTTAGAGAAGAATCATATA
AAGGACTATTTGGTAGATATTGGTGGAGAGATTAGATTAAACGGAACAAATTTGAATAATAAAAGTTGGAATGTTGGCAT
TGATAAACCTTTTGCATATTCAACTGGGCAAATAGAAATTGTAAAACTAAAGAATAGAGCTATTGCTACGTCAGGGAATT
ATCGAAAATATTTTGAGAGTAATGGAAAACACTACTCACACATAATAAACCCCAAGAATGGACAACCAGTTGAATATAAA
ATCGTATCTGCAACCGTGATAGCTGAACGCTGTATGACGGCTGATGGTTTTGCAACAGCCTTTATGGTTTTGCCAGTAAA
GCAATCGCTAGATATTGCAAATAAGCACAACATACCAGTCATGCTAATAGAAGACAAATTTGGAAAGCTAATAACTCATT
ACTCTGTTCCATTTAATCGTATACAAGAAAAACAACTAAAAATGTGA

Upstream 100 bases:

>100_bases
AACATAATTGAAAACAATAAAGCTAATACTTGCATTAACAACATACCTAACTACAAACATTTGCTTTGCAGAGGAAGTTA
AAACCATTAAAGGTTTCACA

Downstream 100 bases:

>100_bases
AGTAACTAAAATAACTAAGGGTTTTATGATGAAAACAAAATTTAAACTAAGCCTGATATGTGTTTCTCTTTTAGCACTAA
CAGCGTGTAACGATGACGAT

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MGNSYNIKWKEKKISANRMHHINTKVKAKLTELNETMSSWDNNSELSLLNNSKEKQFNISPDLEYVISEAIRIHHVTHGA
LDITVDPLISLWGFGATDREYNVPSHTDISKTLKFVGMDKINVADGALTRTSTKVTLNLSSIAKGFAVDAVTIILEKNHI
KDYLVDIGGEIRLNGTNLNNKSWNVGIDKPFAYSTGQIEIVKLKNRAIATSGNYRKYFESNGKHYSHIINPKNGQPVEYK
IVSATVIAERCMTADGFATAFMVLPVKQSLDIANKHNIPVMLIEDKFGKLITHYSVPFNRIQEKQLKM

Sequences:

>Translated_308_residues
MGNSYNIKWKEKKISANRMHHINTKVKAKLTELNETMSSWDNNSELSLLNNSKEKQFNISPDLEYVISEAIRIHHVTHGA
LDITVDPLISLWGFGATDREYNVPSHTDISKTLKFVGMDKINVADGALTRTSTKVTLNLSSIAKGFAVDAVTIILEKNHI
KDYLVDIGGEIRLNGTNLNNKSWNVGIDKPFAYSTGQIEIVKLKNRAIATSGNYRKYFESNGKHYSHIINPKNGQPVEYK
IVSATVIAERCMTADGFATAFMVLPVKQSLDIANKHNIPVMLIEDKFGKLITHYSVPFNRIQEKQLKM
>Mature_307_residues
GNSYNIKWKEKKISANRMHHINTKVKAKLTELNETMSSWDNNSELSLLNNSKEKQFNISPDLEYVISEAIRIHHVTHGAL
DITVDPLISLWGFGATDREYNVPSHTDISKTLKFVGMDKINVADGALTRTSTKVTLNLSSIAKGFAVDAVTIILEKNHIK
DYLVDIGGEIRLNGTNLNNKSWNVGIDKPFAYSTGQIEIVKLKNRAIATSGNYRKYFESNGKHYSHIINPKNGQPVEYKI
VSATVIAERCMTADGFATAFMVLPVKQSLDIANKHNIPVMLIEDKFGKLITHYSVPFNRIQEKQLKM

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=304, Percent_Identity=29.2763157894737, Blast_Score=166, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 34620; Mature: 34489

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNSYNIKWKEKKISANRMHHINTKVKAKLTELNETMSSWDNNSELSLLNNSKEKQFNIS
CCCCCEEEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEECC
PDLEYVISEAIRIHHVTHGALDITVDPLISLWGFGATDREYNVPSHTDISKTLKFVGMDK
CCHHHHHHHHHEEEEEECCEEEEEHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCE
INVADGALTRTSTKVTLNLSSIAKGFAVDAVTIILEKNHIKDYLVDIGGEIRLNGTNLNN
EECCCCCEEECCEEEEEEHHHHHCCCEEEEEEEEEECCCHHHHHHCCCCEEEEECCCCCC
KSWNVGIDKPFAYSTGQIEIVKLKNRAIATSGNYRKYFESNGKHYSHIINPKNGQPVEYK
CCEEECCCCCCEECCCCEEEEEECCEEEECCCCCHHHHHCCCCEEEEEECCCCCCCEEEE
IVSATVIAERCMTADGFATAFMVLPVKQSLDIANKHNIPVMLIEDKFGKLITHYSVPFNR
EEHHHHHHHHHCCCCCCEEEEEEEECHHHCCCCCCCCCCEEEECCCCCCEEEEECCCHHH
IQEKQLKM
HHHHHHCC
>Mature Secondary Structure 
GNSYNIKWKEKKISANRMHHINTKVKAKLTELNETMSSWDNNSELSLLNNSKEKQFNIS
CCCCEEEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEECC
PDLEYVISEAIRIHHVTHGALDITVDPLISLWGFGATDREYNVPSHTDISKTLKFVGMDK
CCHHHHHHHHHEEEEEECCEEEEEHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCE
INVADGALTRTSTKVTLNLSSIAKGFAVDAVTIILEKNHIKDYLVDIGGEIRLNGTNLNN
EECCCCCEEECCEEEEEEHHHHHCCCEEEEEEEEEECCCHHHHHHCCCCEEEEECCCCCC
KSWNVGIDKPFAYSTGQIEIVKLKNRAIATSGNYRKYFESNGKHYSHIINPKNGQPVEYK
CCEEECCCCCCEECCCCEEEEEECCEEEECCCCCHHHHHCCCCEEEEEECCCCCCCEEEE
IVSATVIAERCMTADGFATAFMVLPVKQSLDIANKHNIPVMLIEDKFGKLITHYSVPFNR
EEHHHHHHHHHCCCCCCEEEEEEEECHHHCCCCCCCCCCEEEECCCCCCEEEEECCCHHH
IQEKQLKM
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]