Click here to switch to the map view.

The map label for this gene is apaH [H]

Identifier: 167622853

GI number: 167622853

Start: 1132530

End: 1133363

Strand: Reverse

Name: apaH [H]

Synonym: Shal_0913

Alternate gene names: 167622853

Gene position: 1133363-1132530 (Counterclockwise)

Preceding gene: 167622854

Following gene: 167622852

Centisome position: 21.68

GC content: 45.08

Gene sequence:

>834_bases
ATGGCGAACTATTTTGTAGGTGATATCCAAGGCTGCTTTGATGAATTAACTCTGCTTCTCGATAAAGTCGCTTTTAATCC
ATCGAAGGACTGTTTATGGGCCGTTGGCGATCTCGTAGCTCGTGGCGCAGGCTCTCTTGAGACACTCCGTTTTTTCAAAT
CTTTGTCTGGTTCGGCCAAAGTCGTACTAGGTAATCATGATCTTCACTTGCTGGCCATTCACGGAAAATTGAAGCGGGCC
AATCCAAAAGATCATTTAACCGCCCTTCTCGCCGCGGATGATATAAATAATATTATCGACTGGCTAAGGCTGCAGCCTCT
CTATCAAGATTGGCCTGAAAAAAGGCTTATCATGACTCACGCTGGAGTGCCGCCTAACTGGGACTTAACCACCCTACGTA
ATGAGGCTGATCTTGTTAGCCAAGCGCTCAAGTCAGAAAACTACTTACAAGATCTGATCAGCGAGATGTATACCAACTCG
GTAGATGAGTTTCATACAGGCCTGACAGCGCTTGAAAAACAGATCTATTGCATTAATGCACTGACCCGCATGCGTTACTT
AAAAGCCGATGGACGCTTAGATTTCGACTGTAAGTCCCCACTGCACGATCGTGATAATGACGCACTGGTTCCTTGGTTTA
TCCAAGCCTCCAAATTACCTGACGACTATACCGTAGTATTTGGCCATTGGGCCGCAATTATGGGACAAACTCACCTAGCT
AACCGACAAGCCCTAGATACAGGTTGTTGCTGGGGAGAACACTTGACACTTTGGCATCTTGAGTCGAACCAAAAAATCAT
TCAAAGCAAATTAAAAGACGTTAACAGAAGTTAA

Upstream 100 bases:

>100_bases
CAATGGCGATGAGTTTAAAGCCCCAATATCCGCCTTTCGTTTATCAATTCCTGGTTTACTTCATTAATAACGAAATATAA
ATAACAACACATAGGTAAAA

Downstream 100 bases:

>100_bases
AAAAGAGTTAAACTATCGCTAAATTTGGCCGATAAAGTATTCGTTCTGCGTGTGAAGCGGATGCTGTGACTTGGATAAAA
ATAATAAAAATGGAGCTCCT

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MANYFVGDIQGCFDELTLLLDKVAFNPSKDCLWAVGDLVARGAGSLETLRFFKSLSGSAKVVLGNHDLHLLAIHGKLKRA
NPKDHLTALLAADDINNIIDWLRLQPLYQDWPEKRLIMTHAGVPPNWDLTTLRNEADLVSQALKSENYLQDLISEMYTNS
VDEFHTGLTALEKQIYCINALTRMRYLKADGRLDFDCKSPLHDRDNDALVPWFIQASKLPDDYTVVFGHWAAIMGQTHLA
NRQALDTGCCWGEHLTLWHLESNQKIIQSKLKDVNRS

Sequences:

>Translated_277_residues
MANYFVGDIQGCFDELTLLLDKVAFNPSKDCLWAVGDLVARGAGSLETLRFFKSLSGSAKVVLGNHDLHLLAIHGKLKRA
NPKDHLTALLAADDINNIIDWLRLQPLYQDWPEKRLIMTHAGVPPNWDLTTLRNEADLVSQALKSENYLQDLISEMYTNS
VDEFHTGLTALEKQIYCINALTRMRYLKADGRLDFDCKSPLHDRDNDALVPWFIQASKLPDDYTVVFGHWAAIMGQTHLA
NRQALDTGCCWGEHLTLWHLESNQKIIQSKLKDVNRS
>Mature_276_residues
ANYFVGDIQGCFDELTLLLDKVAFNPSKDCLWAVGDLVARGAGSLETLRFFKSLSGSAKVVLGNHDLHLLAIHGKLKRAN
PKDHLTALLAADDINNIIDWLRLQPLYQDWPEKRLIMTHAGVPPNWDLTTLRNEADLVSQALKSENYLQDLISEMYTNSV
DEFHTGLTALEKQIYCINALTRMRYLKADGRLDFDCKSPLHDRDNDALVPWFIQASKLPDDYTVVFGHWAAIMGQTHLAN
RQALDTGCCWGEHLTLWHLESNQKIIQSKLKDVNRS

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=269, Percent_Identity=44.9814126394052, Blast_Score=236, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 31371; Mature: 31240

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANYFVGDIQGCFDELTLLLDKVAFNPSKDCLWAVGDLVARGAGSLETLRFFKSLSGSAK
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEE
VVLGNHDLHLLAIHGKLKRANPKDHLTALLAADDINNIIDWLRLQPLYQDWPEKRLIMTH
EEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEEEEEE
AGVPPNWDLTTLRNEADLVSQALKSENYLQDLISEMYTNSVDEFHTGLTALEKQIYCINA
CCCCCCCCHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LTRMRYLKADGRLDFDCKSPLHDRDNDALVPWFIQASKLPDDYTVVFGHWAAIMGQTHLA
HHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEHEEEECCCCCCEEEHHHHHHHHHCCHHHC
NRQALDTGCCWGEHLTLWHLESNQKIIQSKLKDVNRS
CCHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
ANYFVGDIQGCFDELTLLLDKVAFNPSKDCLWAVGDLVARGAGSLETLRFFKSLSGSAK
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEE
VVLGNHDLHLLAIHGKLKRANPKDHLTALLAADDINNIIDWLRLQPLYQDWPEKRLIMTH
EEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEEEEEE
AGVPPNWDLTTLRNEADLVSQALKSENYLQDLISEMYTNSVDEFHTGLTALEKQIYCINA
CCCCCCCCHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LTRMRYLKADGRLDFDCKSPLHDRDNDALVPWFIQASKLPDDYTVVFGHWAAIMGQTHLA
HHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEHEEEECCCCCCEEEHHHHHHHHHCCHHHC
NRQALDTGCCWGEHLTLWHLESNQKIIQSKLKDVNRS
CCHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA