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The map label for this gene is obgE [H]

Identifier: 167622847

GI number: 167622847

Start: 1126732

End: 1127895

Strand: Direct

Name: obgE [H]

Synonym: Shal_0907

Alternate gene names: 167622847

Gene position: 1126732-1127895 (Clockwise)

Preceding gene: 167622846

Following gene: 167622848

Centisome position: 21.56

GC content: 45.7

Gene sequence:

>1164_bases
ATGAAGTTTGTCGATGAAGCTATTATCCGTGTAGAAGCCGGAAATGGTGGCAGTGGTTGCGTTAGCTTTAGACGTGAAAA
ATATGTTCCTGATGGTGGGCCTGACGGTGGTGATGGTGGCGACGGCGGTAGTGTATATCTACAAGCCGATGAAAACCTCA
ACACACTGATCACTTTTCAGTTTGAACGCTTCCATATTGCCGAGCGTGGTAAGAATGGTCGTGGACGTGACTGTACTGGT
CACGGCGGTGAAGATTTGATCCTTAAAGTGCCTGTAGGTACTCGCGCTATCGATAACGATACTGAAGAGTCACTTGGTGA
CTTAACCACTCACGGGCAAAAACTGCTTGTGGCTAAAGGTGGTTTCCATGGTCTAGGTAATACTCGTTTCAAGAGTAGTA
CTAACCGTGCGCCAAGACAGAAGACTTTAGGCACCGACGGTGAAGTACGTAGCCTTAAGCTAGAGCTGCTATTGTTAGCG
GACGTGGGCTTGTTAGGTATGCCTAACGCAGGTAAGTCGACTTTTATTCGTTCAGTATCTAAGGCTAAGCCTAAAGTGGC
TGACTATCCGTTTACAACTTTGGTTCCTAACTTAGGCGTTGTTAACCCTAGACCAGGCCAAAGCTTTGTGATCGCCGATA
TTCCAGGTCTTATCGAAGGTGCGGCTGATGGCGCAGGTCTTGGTGTTCAATTCTTGAAGCACTTAGAGCGCTGTCGTGTA
TTGCTGCATATTCTAGATGTTGAGCCTATTGATGGTAGCGATCCAGTTGAATCTGCTCGTGCAATCGTTGGTGAGCTTGA
GAAGCACTCTCCGAAGCTTGCTGGCAAGCCTCGCTGGTTAGTGATCAACAAAGCTGATTTGATGTTGGAAGAAGAGCTGC
AAGAGCGAATCGACCATATCGTTAAAGAGCTAGAGTGGGATGGCGATGTCTACACGATTTCTGCTTATAACCGCGAAGGT
ACAGCTGAGTTAGCCGTTAAACTATTAGACTTTATTGCTTCACTTCCACCTGAAGAAGAAGTGGATGCCGATGCTGAAGT
CGAGTTTAAGTGGGATAACTATCATCAGAGCGCTAATGAATCAGTCAATGAAGATTTTGACGATGATTTCGATGACGATT
TTGATGAAGATGATTATGATGTAGAGATTATCTACCAAAGATAA

Upstream 100 bases:

>100_bases
ATTGGTGGGGCTTTGTTTTTTCAAAATTAAGTAAATTGTGTTTTGGCGACTAGAATCGTTAAGAGTATAATTCTTTCATT
CTGTGGTGCCAGGAGTTGGT

Downstream 100 bases:

>100_bases
GTATTCGCATAAAAGGAAGTTGAGAATAGGTGTACGCTACAACGCAAAATGACATTACTCGTCAAGTCGTTAGGGTTGCT
CAACTTCTTTTAGCTTATGG

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MKFVDEAIIRVEAGNGGSGCVSFRREKYVPDGGPDGGDGGDGGSVYLQADENLNTLITFQFERFHIAERGKNGRGRDCTG
HGGEDLILKVPVGTRAIDNDTEESLGDLTTHGQKLLVAKGGFHGLGNTRFKSSTNRAPRQKTLGTDGEVRSLKLELLLLA
DVGLLGMPNAGKSTFIRSVSKAKPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAADGAGLGVQFLKHLERCRV
LLHILDVEPIDGSDPVESARAIVGELEKHSPKLAGKPRWLVINKADLMLEEELQERIDHIVKELEWDGDVYTISAYNREG
TAELAVKLLDFIASLPPEEEVDADAEVEFKWDNYHQSANESVNEDFDDDFDDDFDEDDYDVEIIYQR

Sequences:

>Translated_387_residues
MKFVDEAIIRVEAGNGGSGCVSFRREKYVPDGGPDGGDGGDGGSVYLQADENLNTLITFQFERFHIAERGKNGRGRDCTG
HGGEDLILKVPVGTRAIDNDTEESLGDLTTHGQKLLVAKGGFHGLGNTRFKSSTNRAPRQKTLGTDGEVRSLKLELLLLA
DVGLLGMPNAGKSTFIRSVSKAKPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAADGAGLGVQFLKHLERCRV
LLHILDVEPIDGSDPVESARAIVGELEKHSPKLAGKPRWLVINKADLMLEEELQERIDHIVKELEWDGDVYTISAYNREG
TAELAVKLLDFIASLPPEEEVDADAEVEFKWDNYHQSANESVNEDFDDDFDDDFDEDDYDVEIIYQR
>Mature_387_residues
MKFVDEAIIRVEAGNGGSGCVSFRREKYVPDGGPDGGDGGDGGSVYLQADENLNTLITFQFERFHIAERGKNGRGRDCTG
HGGEDLILKVPVGTRAIDNDTEESLGDLTTHGQKLLVAKGGFHGLGNTRFKSSTNRAPRQKTLGTDGEVRSLKLELLLLA
DVGLLGMPNAGKSTFIRSVSKAKPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAADGAGLGVQFLKHLERCRV
LLHILDVEPIDGSDPVESARAIVGELEKHSPKLAGKPRWLVINKADLMLEEELQERIDHIVKELEWDGDVYTISAYNREG
TAELAVKLLDFIASLPPEEEVDADAEVEFKWDNYHQSANESVNEDFDDDFDDDFDEDDYDVEIIYQR

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=329, Percent_Identity=38.2978723404255, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI111955139, Length=312, Percent_Identity=33.6538461538462, Blast_Score=141, Evalue=8e-34,
Organism=Homo sapiens, GI111955063, Length=145, Percent_Identity=39.3103448275862, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI4758796, Length=118, Percent_Identity=36.4406779661017, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI58761500, Length=138, Percent_Identity=30.4347826086957, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI4557537, Length=121, Percent_Identity=33.8842975206612, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1789574, Length=364, Percent_Identity=64.8351648351648, Blast_Score=435, Evalue=1e-123,
Organism=Escherichia coli, GI1787454, Length=100, Percent_Identity=36, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=322, Percent_Identity=38.1987577639752, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17552324, Length=321, Percent_Identity=28.6604361370716, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17509631, Length=128, Percent_Identity=35.9375, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17555344, Length=118, Percent_Identity=34.7457627118644, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=188, Percent_Identity=37.2340425531915, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6319281, Length=128, Percent_Identity=35.15625, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20129375, Length=308, Percent_Identity=40.2597402597403, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24585318, Length=288, Percent_Identity=37.5, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24640873, Length=129, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24640877, Length=129, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24640875, Length=129, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17981711, Length=118, Percent_Identity=33.8983050847458, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 42406; Mature: 42406

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVDEAIIRVEAGNGGSGCVSFRREKYVPDGGPDGGDGGDGGSVYLQADENLNTLITFQ
CCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEE
FERFHIAERGKNGRGRDCTGHGGEDLILKVPVGTRAIDNDTEESLGDLTTHGQKLLVAKG
EEEEEHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEECC
GFHGLGNTRFKSSTNRAPRQKTLGTDGEVRSLKLELLLLADVGLLGMPNAGKSTFIRSVS
CCCCCCCCCCCCCCCCCCCHHHCCCCCCEEEEEEEEEEEECCCEECCCCCCHHHHHHHHH
KAKPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAADGAGLGVQFLKHLERCRV
HCCCCCCCCCHHHHCCCCCCCCCCCCCEEEEEECCHHHHCCCCCCCHHHHHHHHHHHHHH
LLHILDVEPIDGSDPVESARAIVGELEKHSPKLAGKPRWLVINKADLMLEEELQERIDHI
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHH
VKELEWDGDVYTISAYNREGTAELAVKLLDFIASLPPEEEVDADAEVEFKWDNYHQSANE
HHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHCCCCCEEEEEECCHHHHCCC
SVNEDFDDDFDDDFDEDDYDVEIIYQR
CCCCCCCCCCCCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MKFVDEAIIRVEAGNGGSGCVSFRREKYVPDGGPDGGDGGDGGSVYLQADENLNTLITFQ
CCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEE
FERFHIAERGKNGRGRDCTGHGGEDLILKVPVGTRAIDNDTEESLGDLTTHGQKLLVAKG
EEEEEHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEECC
GFHGLGNTRFKSSTNRAPRQKTLGTDGEVRSLKLELLLLADVGLLGMPNAGKSTFIRSVS
CCCCCCCCCCCCCCCCCCCHHHCCCCCCEEEEEEEEEEEECCCEECCCCCCHHHHHHHHH
KAKPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAADGAGLGVQFLKHLERCRV
HCCCCCCCCCHHHHCCCCCCCCCCCCCEEEEEECCHHHHCCCCCCCHHHHHHHHHHHHHH
LLHILDVEPIDGSDPVESARAIVGELEKHSPKLAGKPRWLVINKADLMLEEELQERIDHI
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHH
VKELEWDGDVYTISAYNREGTAELAVKLLDFIASLPPEEEVDADAEVEFKWDNYHQSANE
HHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHCCCCCEEEEEECCHHHHCCC
SVNEDFDDDFDDDFDEDDYDVEIIYQR
CCCCCCCCCCCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA