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The map label for this gene is sdaA [H]

Identifier: 167622764

GI number: 167622764

Start: 1027770

End: 1029137

Strand: Direct

Name: sdaA [H]

Synonym: Shal_0824

Alternate gene names: 167622764

Gene position: 1027770-1029137 (Clockwise)

Preceding gene: 167622763

Following gene: 167622766

Centisome position: 19.66

GC content: 47.81

Gene sequence:

>1368_bases
ATGTTTAGCGCATTTGATATTTTTAAGATAGGTGTGGGCCCATCGAGCTCTCATACTGTCGGGCCGATGAAGGCCGCCAA
AGAGTTTATCGATGATGTTCGTCAGACCGGTCAGTTTGAGCAAGTGACTCGTTTAAGTGTTGAGATTTTTGGTTCTTTAT
CGTTAACCGGTAAAGGCCACCATACCGATATCGCCATTATTGTCGGCCTAGGTGGTAACTCACCTGAGAGCGTTGATATT
GATGCTATCCCTGGTTTTATTGCTGACGTTGAGCAGACTCAGAAGCTACCTATGGGCAGCGAAAAGCAGCTGGTAGACTT
TGGTCACGATGCGGTGATTTTCCATAGTCACGCATTACCATTGCATGAAAACGGCATGATGCTACACGCTTATAAAGGCG
ATGAAGTTGTGCTTAGTAAGACCTACTACTCAGTAGGCGGTGGCTTTATTGTTGAAGAGTCAAAATTCGGCAAAGATGTT
GAAAACCCTGTTGAAGTGCCATACCCGTTTAATTTTGCTGATGAGCTACTGGCGATCTGTAAAGAGACCGGTCTAAGCAT
CAGCACCATCATGTTCAAGAATGAATTGGCATTCAACAGTGAACAAGCTATTTACGATGGCTTTGGTGCAGTATGGGAAA
CCATGCATCAGGCGATTGAAAAAGGCTGTCAAACTGAAGGTGTACTTGCCGGTCCGCTACGAGTAGCTCGTCGCGCTCCA
GCACTTTACCGCCAGTTACAAACGGGTGAACGTCTATCAAGCGACCCAATGGAAATCGTTGACTGGATCAACGTGTTTGC
TATGGCTGTTAGCGAAGAAAACGCTGCTGGTGGCCGCGTAGTTACATCACCAACAAACGGCGCAGCGGGTATCATTCCTG
CAGTACTAGCGTATTACGACAAGTTCATTAAACCTGTTGGTAAGCAAGAATACACGCGCTTCTTTCTCGCTGCGGCTGCA
GTGGGTTCATTATACAAGCGCAACGCTTCTATCTCTGGCGCTGAAGTCGGTTGTCAGGGTGAAGTTGGCGTAGCGTGTTC
TATGGCGGCAGCAGGTCTTGCTGAAGTCATGGGCGCTAATGCTGAGCAAGTTTGTATGGCGGCTGAGATTGGCATGGAGC
ATAACTTAGGTTTGACCTGTGACCCAGTTGCAGGCCAAGTACAAGTACCGTGTATTGAGCGTAACGCGATTGCTGCTGTT
AAGGCGATTAACTCTACGCGTATGGCTATGCGTCGTAACTGCGCACCAAAGGTGAGCTTAGATAAAGTTATCGCGACTAT
GTACGAGACGGGTAAAGATATGCACGTTAAGTACCGCGAAACCAGCCAAGGCGGTTTGGCTATCAAGGTAACCAGCATCT
GCGGTTAA

Upstream 100 bases:

>100_bases
CGCTCTTGCCTAGGCTTTATCAGTTAAGTTTTATCGTTCCATATTGTTTGACTATGGGCTAGGAGTTCTCTTGGTCCTCC
TCTATTACCGAGGTGATTTA

Downstream 100 bases:

>100_bases
CTTTTTATTGCCAGATTCTGTCTGGCATGAGTAGCAAAAAGGCCATCAAATGATGGCCTTTTTAATGTCTGTCATTTGCT
CAAGTCGAGGAGCGGCGATA

Product: L-serine dehydratase 1

Products: NA

Alternate protein names: SDH 1; L-serine deaminase 1; L-SD1 [H]

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MFSAFDIFKIGVGPSSSHTVGPMKAAKEFIDDVRQTGQFEQVTRLSVEIFGSLSLTGKGHHTDIAIIVGLGGNSPESVDI
DAIPGFIADVEQTQKLPMGSEKQLVDFGHDAVIFHSHALPLHENGMMLHAYKGDEVVLSKTYYSVGGGFIVEESKFGKDV
ENPVEVPYPFNFADELLAICKETGLSISTIMFKNELAFNSEQAIYDGFGAVWETMHQAIEKGCQTEGVLAGPLRVARRAP
ALYRQLQTGERLSSDPMEIVDWINVFAMAVSEENAAGGRVVTSPTNGAAGIIPAVLAYYDKFIKPVGKQEYTRFFLAAAA
VGSLYKRNASISGAEVGCQGEVGVACSMAAAGLAEVMGANAEQVCMAAEIGMEHNLGLTCDPVAGQVQVPCIERNAIAAV
KAINSTRMAMRRNCAPKVSLDKVIATMYETGKDMHVKYRETSQGGLAIKVTSICG

Sequences:

>Translated_455_residues
MFSAFDIFKIGVGPSSSHTVGPMKAAKEFIDDVRQTGQFEQVTRLSVEIFGSLSLTGKGHHTDIAIIVGLGGNSPESVDI
DAIPGFIADVEQTQKLPMGSEKQLVDFGHDAVIFHSHALPLHENGMMLHAYKGDEVVLSKTYYSVGGGFIVEESKFGKDV
ENPVEVPYPFNFADELLAICKETGLSISTIMFKNELAFNSEQAIYDGFGAVWETMHQAIEKGCQTEGVLAGPLRVARRAP
ALYRQLQTGERLSSDPMEIVDWINVFAMAVSEENAAGGRVVTSPTNGAAGIIPAVLAYYDKFIKPVGKQEYTRFFLAAAA
VGSLYKRNASISGAEVGCQGEVGVACSMAAAGLAEVMGANAEQVCMAAEIGMEHNLGLTCDPVAGQVQVPCIERNAIAAV
KAINSTRMAMRRNCAPKVSLDKVIATMYETGKDMHVKYRETSQGGLAIKVTSICG
>Mature_455_residues
MFSAFDIFKIGVGPSSSHTVGPMKAAKEFIDDVRQTGQFEQVTRLSVEIFGSLSLTGKGHHTDIAIIVGLGGNSPESVDI
DAIPGFIADVEQTQKLPMGSEKQLVDFGHDAVIFHSHALPLHENGMMLHAYKGDEVVLSKTYYSVGGGFIVEESKFGKDV
ENPVEVPYPFNFADELLAICKETGLSISTIMFKNELAFNSEQAIYDGFGAVWETMHQAIEKGCQTEGVLAGPLRVARRAP
ALYRQLQTGERLSSDPMEIVDWINVFAMAVSEENAAGGRVVTSPTNGAAGIIPAVLAYYDKFIKPVGKQEYTRFFLAAAA
VGSLYKRNASISGAEVGCQGEVGVACSMAAAGLAEVMGANAEQVCMAAEIGMEHNLGLTCDPVAGQVQVPCIERNAIAAV
KAINSTRMAMRRNCAPKVSLDKVIATMYETGKDMHVKYRETSQGGLAIKVTSICG

Specific function: Deaminates also threonine, particularly when it is present in high concentration [H]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=451, Percent_Identity=68.2926829268293, Blast_Score=654, Evalue=0.0,
Organism=Escherichia coli, GI48994925, Length=456, Percent_Identity=65.1315789473684, Blast_Score=610, Evalue=1e-176,
Organism=Escherichia coli, GI1789161, Length=453, Percent_Identity=64.6799116997792, Blast_Score=610, Evalue=1e-176,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 48691; Mature: 48691

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSAFDIFKIGVGPSSSHTVGPMKAAKEFIDDVRQTGQFEQVTRLSVEIFGSLSLTGKGH
CCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHEEEEEEEEEECCCCC
HTDIAIIVGLGGNSPESVDIDAIPGFIADVEQTQKLPMGSEKQLVDFGHDAVIFHSHALP
CCEEEEEEEECCCCCCCEEHHCCCCHHHHHHHHHCCCCCCCCHHHHCCCCEEEEECCCCC
LHENGMMLHAYKGDEVVLSKTYYSVGGGFIVEESKFGKDVENPVEVPYPFNFADELLAIC
CCCCCEEEEEECCCEEEEEEEEEECCCCEEEECHHCCCCCCCCCCCCCCCCHHHHHHHHH
KETGLSISTIMFKNELAFNSEQAIYDGFGAVWETMHQAIEKGCQTEGVLAGPLRVARRAP
HHCCCEEEEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHCH
ALYRQLQTGERLSSDPMEIVDWINVFAMAVSEENAAGGRVVTSPTNGAAGIIPAVLAYYD
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHH
KFIKPVGKQEYTRFFLAAAAVGSLYKRNASISGAEVGCQGEVGVACSMAAAGLAEVMGAN
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
AEQVCMAAEIGMEHNLGLTCDPVAGQVQVPCIERNAIAAVKAINSTRMAMRRNCAPKVSL
HHHHHHHHHCCCCCCCCEEECCCCCCEECCEECCCHHHHHHHHHHHHHHHHHCCCCCCHH
DKVIATMYETGKDMHVKYRETSQGGLAIKVTSICG
HHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCC
>Mature Secondary Structure
MFSAFDIFKIGVGPSSSHTVGPMKAAKEFIDDVRQTGQFEQVTRLSVEIFGSLSLTGKGH
CCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHEEEEEEEEEECCCCC
HTDIAIIVGLGGNSPESVDIDAIPGFIADVEQTQKLPMGSEKQLVDFGHDAVIFHSHALP
CCEEEEEEEECCCCCCCEEHHCCCCHHHHHHHHHCCCCCCCCHHHHCCCCEEEEECCCCC
LHENGMMLHAYKGDEVVLSKTYYSVGGGFIVEESKFGKDVENPVEVPYPFNFADELLAIC
CCCCCEEEEEECCCEEEEEEEEEECCCCEEEECHHCCCCCCCCCCCCCCCCHHHHHHHHH
KETGLSISTIMFKNELAFNSEQAIYDGFGAVWETMHQAIEKGCQTEGVLAGPLRVARRAP
HHCCCEEEEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHCH
ALYRQLQTGERLSSDPMEIVDWINVFAMAVSEENAAGGRVVTSPTNGAAGIIPAVLAYYD
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHH
KFIKPVGKQEYTRFFLAAAAVGSLYKRNASISGAEVGCQGEVGVACSMAAAGLAEVMGAN
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
AEQVCMAAEIGMEHNLGLTCDPVAGQVQVPCIERNAIAAVKAINSTRMAMRRNCAPKVSL
HHHHHHHHHCCCCCCCCEEECCCCCCEECCEECCCHHHHHHHHHHHHHHHHHCCCCCCHH
DKVIATMYETGKDMHVKYRETSQGGLAIKVTSICG
HHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2504697; 8436113; 9097040; 9278503 [H]