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The map label for this gene is fbp

Identifier: 167622724

GI number: 167622724

Start: 978116

End: 979105

Strand: Reverse

Name: fbp

Synonym: Shal_0784

Alternate gene names: 167622724

Gene position: 979105-978116 (Counterclockwise)

Preceding gene: 167622726

Following gene: 167622715

Centisome position: 18.73

GC content: 46.97

Gene sequence:

>990_bases
ATGCAAACTCTGGCTGAAAACCTGACATCACAAGCAATTTCTCCTACTCTTGAAAAGCTGATCCTGACCCTAGCTAACAC
CTCAAAAGAGATTAGCCATGCAGTACGCCACGGCGCACTCGCAGGCGTGCTAGGTGCAACAGAGCAGGAAAATGTTCAAG
GCGAAACACAGAAGAAACTCGATATCATCACCAATGATATGCTCAAAGATGCCCTAAAGGCCGACGGTACAGTGCGTGGT
ATCGCCTCTGAAGAGGAAGACTATGTGGTTGAAGCCGATGCCAACGGTGAGTTCCTAGTCTGTTTTGATCCGCTAGATGG
TTCTTCAAACATCGACATTAACTCACTTGTCGGCACCATCTTCTCGGTATTACCAGCGCCAGCAGGCGAGCTAACAGAAA
AGAGTTTCCTACAAGCAGGTCACAACCAAGTTGCCGCAGGTTATGTACTATATGGCCCATCAACCATGCTTGCGCTAACT
ACAGGTCAAGGCGTACAGCTATTCACCCTAAACCCAGAGACTAACCAGTTCTTGCTAACCAATGCTGCTATGGCTGTCAG
CAAAGACACCGGCGAATTTGCCATTAACATGTCAAACCAACGCTTCTGGGAAGCGCCAATGCAGACTTACATTAGCGATT
TGCTACTAGGTAAAATTGGCCCACGTGAAAAGTCATTCAACATGCGCTGGATTGCAGCCATGGTTGGTGACGTGCACCGC
GTACTTTGTCGCGGCGGTATCTTCACTTATCCGACAGATAACAAAAATCCAGAGAAGCCATACAAGCTACGTTTAATGTA
CGAAGCTAACCCAATGGCATTCTTAGTTGAGCAAGCAGGTGGTAAAGCGTCAACGGGTTATGAAACCATTATGGATATTG
AGCCAACTGCAATTCACCAACGTGTTGCGGTGATCTTAGGCTCAGCCAATGAAGTTGATGCTTGTCTTGAATATCACGGT
ATTGATTACAGCGAAGAACCAGCTTTATAG

Upstream 100 bases:

>100_bases
AAACTGCCATACTCAGGTATCATCGCGTCAATAATAAAGAATACACTTTTGTCCTGACCTCAAACTCAATTTACTCACGT
AAAATTGTATAGGAAACAAG

Downstream 100 bases:

>100_bases
GTTCTAGGAAAGGCTGAGACGGTAAGAGCCGAGAAAGCTAAGACGGTGTAGGCTAAGACGGTAAAAGCCGGAAAAGAAAA
AATCTAAAAGAAAAGCACAA

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MQTLAENLTSQAISPTLEKLILTLANTSKEISHAVRHGALAGVLGATEQENVQGETQKKLDIITNDMLKDALKADGTVRG
IASEEEDYVVEADANGEFLVCFDPLDGSSNIDINSLVGTIFSVLPAPAGELTEKSFLQAGHNQVAAGYVLYGPSTMLALT
TGQGVQLFTLNPETNQFLLTNAAMAVSKDTGEFAINMSNQRFWEAPMQTYISDLLLGKIGPREKSFNMRWIAAMVGDVHR
VLCRGGIFTYPTDNKNPEKPYKLRLMYEANPMAFLVEQAGGKASTGYETIMDIEPTAIHQRVAVILGSANEVDACLEYHG
IDYSEEPAL

Sequences:

>Translated_329_residues
MQTLAENLTSQAISPTLEKLILTLANTSKEISHAVRHGALAGVLGATEQENVQGETQKKLDIITNDMLKDALKADGTVRG
IASEEEDYVVEADANGEFLVCFDPLDGSSNIDINSLVGTIFSVLPAPAGELTEKSFLQAGHNQVAAGYVLYGPSTMLALT
TGQGVQLFTLNPETNQFLLTNAAMAVSKDTGEFAINMSNQRFWEAPMQTYISDLLLGKIGPREKSFNMRWIAAMVGDVHR
VLCRGGIFTYPTDNKNPEKPYKLRLMYEANPMAFLVEQAGGKASTGYETIMDIEPTAIHQRVAVILGSANEVDACLEYHG
IDYSEEPAL
>Mature_329_residues
MQTLAENLTSQAISPTLEKLILTLANTSKEISHAVRHGALAGVLGATEQENVQGETQKKLDIITNDMLKDALKADGTVRG
IASEEEDYVVEADANGEFLVCFDPLDGSSNIDINSLVGTIFSVLPAPAGELTEKSFLQAGHNQVAAGYVLYGPSTMLALT
TGQGVQLFTLNPETNQFLLTNAAMAVSKDTGEFAINMSNQRFWEAPMQTYISDLLLGKIGPREKSFNMRWIAAMVGDVHR
VLCRGGIFTYPTDNKNPEKPYKLRLMYEANPMAFLVEQAGGKASTGYETIMDIEPTAIHQRVAVILGSANEVDACLEYHG
IDYSEEPAL

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family

Homologues:

Organism=Homo sapiens, GI22907028, Length=301, Percent_Identity=41.1960132890365, Blast_Score=232, Evalue=4e-61,
Organism=Homo sapiens, GI189083692, Length=301, Percent_Identity=42.1926910299003, Blast_Score=229, Evalue=2e-60,
Organism=Homo sapiens, GI16579888, Length=301, Percent_Identity=42.1926910299003, Blast_Score=229, Evalue=2e-60,
Organism=Escherichia coli, GI1790679, Length=323, Percent_Identity=43.0340557275542, Blast_Score=238, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI17508131, Length=308, Percent_Identity=41.2337662337662, Blast_Score=230, Evalue=7e-61,
Organism=Saccharomyces cerevisiae, GI6323409, Length=297, Percent_Identity=39.7306397306397, Blast_Score=223, Evalue=3e-59,
Organism=Drosophila melanogaster, GI45550998, Length=320, Percent_Identity=39.0625, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI19921562, Length=320, Percent_Identity=39.0625, Blast_Score=202, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): F16PA_SHEHH (B0TTL6)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001673018.1
- ProteinModelPortal:   B0TTL6
- SMR:   B0TTL6
- GeneID:   5902875
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_0784
- HOGENOM:   HBG731261
- OMA:   HWEAPVQ
- ProtClustDB:   PRK09293
- BioCyc:   SHAL458817:SHAL_0784-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01855
- InterPro:   IPR000146
- PANTHER:   PTHR11556
- PRINTS:   PR00115

Pfam domain/function: PF00316 FBPase

EC number: =3.1.3.11

Molecular weight: Translated: 35697; Mature: 35697

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS00124 FBPASE; PS00659 GLYCOSYL_HYDROL_F5

Important sites: BINDING 196-196 BINDING 262-262

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLAENLTSQAISPTLEKLILTLANTSKEISHAVRHGALAGVLGATEQENVQGETQKKL
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
DIITNDMLKDALKADGTVRGIASEEEDYVVEADANGEFLVCFDPLDGSSNIDINSLVGTI
HHHHHHHHHHHHHCCCCEEECCCCCCCEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHH
FSVLPAPAGELTEKSFLQAGHNQVAAGYVLYGPSTMLALTTGQGVQLFTLNPETNQFLLT
HHHHCCCCCHHHHHHHHHCCCCCEEEEEEEECCCEEEEEECCCCEEEEEECCCCCEEEEE
NAAMAVSKDTGEFAINMSNQRFWEAPMQTYISDLLLGKIGPREKSFNMRWIAAMVGDVHR
EEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
VLCRGGIFTYPTDNKNPEKPYKLRLMYEANPMAFLVEQAGGKASTGYETIMDIEPTAIHQ
HHHCCCEEECCCCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCEEEECCHHHHHH
RVAVILGSANEVDACLEYHGIDYSEEPAL
HHHEEECCCCHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MQTLAENLTSQAISPTLEKLILTLANTSKEISHAVRHGALAGVLGATEQENVQGETQKKL
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
DIITNDMLKDALKADGTVRGIASEEEDYVVEADANGEFLVCFDPLDGSSNIDINSLVGTI
HHHHHHHHHHHHHCCCCEEECCCCCCCEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHH
FSVLPAPAGELTEKSFLQAGHNQVAAGYVLYGPSTMLALTTGQGVQLFTLNPETNQFLLT
HHHHCCCCCHHHHHHHHHCCCCCEEEEEEEECCCEEEEEECCCCEEEEEECCCCCEEEEE
NAAMAVSKDTGEFAINMSNQRFWEAPMQTYISDLLLGKIGPREKSFNMRWIAAMVGDVHR
EEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
VLCRGGIFTYPTDNKNPEKPYKLRLMYEANPMAFLVEQAGGKASTGYETIMDIEPTAIHQ
HHHCCCEEECCCCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCEEEECCHHHHHH
RVAVILGSANEVDACLEYHGIDYSEEPAL
HHHEEECCCCHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA