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The map label for this gene is atoC [H]

Identifier: 167622714

GI number: 167622714

Start: 962283

End: 963665

Strand: Reverse

Name: atoC [H]

Synonym: Shal_0774

Alternate gene names: 167622714

Gene position: 963665-962283 (Counterclockwise)

Preceding gene: 167622715

Following gene: 167622709

Centisome position: 18.44

GC content: 50.47

Gene sequence:

>1383_bases
ATGAAACTTGCTAGAAACATTCTCCTAGTTGATGACGAAGCCTCTTGGCTACGAACCCTGTCTATCACCCTTAACCGATT
GGTGCCTGAAGCCAAAATTGATACCTGTGTCGATAGCCGTCAGGTGATGAGTCGGCTGCAGACGGGTGATTATGCCTTGG
TGCTGCTGGATCTGACCATGCCGTTTCACTCCGGTGAAGATCTGCTAGAGATGATCCGTAGCGAGTTTCCTAAGACCCGT
GTACTGATAGTCACAGGCGTAAACGAGGTCGACACCGCGGTGCGTTGCATTAAAAACGGTGCCTATGATTACTTTATCAA
AACCGATAAGGTCGACGACCTTGCCCGCACCGTGCGCCGTGCACTTGAAGTGGTAGGCCTTGAACGTAACTATCTGCGCA
TCAAAGAGAGCTTTTTAAGCCGTACCTTAAGCCGCCCAGAGGTATTTAATAATATCCTCACCTGCGAGCCCGCACTGCTA
GATCAGTTTCGTTATCTGGAGGCGGTGGCCTTAAGCCCAGAGCCTATCCTTATTCAAGGTGAAAGCGGTACCGGCAAAGA
TGAGTTTGCCAAGTCTTGCCATCAGCTTATCTGCGCCGACGCCCCCTTTGTTAACGTAAATTTAGCAGGGATCGGCACCT
CGGCATTCGAGCTACAGCTATTTGGCCAACTCCACACAGGCGAAGACGGTCAGATCAGCGCGCAAGCCGGGGTGCTGCAT
CAGGTGCAGTCAGGACTGCTGTATCTAAATGAAATTGGCGACTTGCCCATTGAAGCCCAAGCTAAGCTTGTGGATGTGAT
TGAGCATAAGCAGTACTACCCTATCGGCAGTGACAGAGCCTATCCGGTACTGTGTAAGATCATCACCTCGACTCAGCACG
ACTTATTAGCCCTTAACCAAGCGGGTAAATTTAGAAGCGATCTGCTCTATCGCCTGCGTTCTCACACCATCAAACTACCA
CCACTGCGGCAACGTAAACTGGATCTGTCGATGCTGATTAATCACTTTATCAGTTTGGCGGCCAAGGAGATGGGACTGTC
AGAGCCACAGCAACCCGCCTCCCTTGCCCAGCAACTCAGTGAATATGATTTCCCCGGTAATCTACACGAGCTTAAGGGGA
TGGTGTTTGACGCCGTTAGCCGCAGTGACGGTATTGCACTGAATATCACTCCCTTTATGGAAGCGATTAATCTCAGCAAG
TCGAGTCATGCAACACAAAGCGATCAGATACTCTTCCCCAAAAACCTACCGACATTGGCGCAGATGAGTGACGCCCTCAT
TCAAGAAGCGATGAACCGCACTGCTAATAGCCAAACCGCAGCGGCGCAGATGCTAGGTATAAGCCAGAGTGCTTTGAGCC
GGCGCATCACTAAAGAAAAATAA

Upstream 100 bases:

>100_bases
CTGAAATATTTACCAGCACAGCACTAATATACAGTACGGCACCGAATTAAAACCTGAGAAGCTCTGAACTGAACAGATAT
TTAATAGGATTGGTATCACC

Downstream 100 bases:

>100_bases
CCAAAGATAAGAAACTAAAGAAAAGAAACAAGAAGCAGAAAACAAAAATGCCAGCAAGTTGCTGGCATTTTTTATCTTTA
ATAATAGAGGGCTCTACAGC

Product: Fis family two component sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MKLARNILLVDDEASWLRTLSITLNRLVPEAKIDTCVDSRQVMSRLQTGDYALVLLDLTMPFHSGEDLLEMIRSEFPKTR
VLIVTGVNEVDTAVRCIKNGAYDYFIKTDKVDDLARTVRRALEVVGLERNYLRIKESFLSRTLSRPEVFNNILTCEPALL
DQFRYLEAVALSPEPILIQGESGTGKDEFAKSCHQLICADAPFVNVNLAGIGTSAFELQLFGQLHTGEDGQISAQAGVLH
QVQSGLLYLNEIGDLPIEAQAKLVDVIEHKQYYPIGSDRAYPVLCKIITSTQHDLLALNQAGKFRSDLLYRLRSHTIKLP
PLRQRKLDLSMLINHFISLAAKEMGLSEPQQPASLAQQLSEYDFPGNLHELKGMVFDAVSRSDGIALNITPFMEAINLSK
SSHATQSDQILFPKNLPTLAQMSDALIQEAMNRTANSQTAAAQMLGISQSALSRRITKEK

Sequences:

>Translated_460_residues
MKLARNILLVDDEASWLRTLSITLNRLVPEAKIDTCVDSRQVMSRLQTGDYALVLLDLTMPFHSGEDLLEMIRSEFPKTR
VLIVTGVNEVDTAVRCIKNGAYDYFIKTDKVDDLARTVRRALEVVGLERNYLRIKESFLSRTLSRPEVFNNILTCEPALL
DQFRYLEAVALSPEPILIQGESGTGKDEFAKSCHQLICADAPFVNVNLAGIGTSAFELQLFGQLHTGEDGQISAQAGVLH
QVQSGLLYLNEIGDLPIEAQAKLVDVIEHKQYYPIGSDRAYPVLCKIITSTQHDLLALNQAGKFRSDLLYRLRSHTIKLP
PLRQRKLDLSMLINHFISLAAKEMGLSEPQQPASLAQQLSEYDFPGNLHELKGMVFDAVSRSDGIALNITPFMEAINLSK
SSHATQSDQILFPKNLPTLAQMSDALIQEAMNRTANSQTAAAQMLGISQSALSRRITKEK
>Mature_460_residues
MKLARNILLVDDEASWLRTLSITLNRLVPEAKIDTCVDSRQVMSRLQTGDYALVLLDLTMPFHSGEDLLEMIRSEFPKTR
VLIVTGVNEVDTAVRCIKNGAYDYFIKTDKVDDLARTVRRALEVVGLERNYLRIKESFLSRTLSRPEVFNNILTCEPALL
DQFRYLEAVALSPEPILIQGESGTGKDEFAKSCHQLICADAPFVNVNLAGIGTSAFELQLFGQLHTGEDGQISAQAGVLH
QVQSGLLYLNEIGDLPIEAQAKLVDVIEHKQYYPIGSDRAYPVLCKIITSTQHDLLALNQAGKFRSDLLYRLRSHTIKLP
PLRQRKLDLSMLINHFISLAAKEMGLSEPQQPASLAQQLSEYDFPGNLHELKGMVFDAVSRSDGIALNITPFMEAINLSK
SSHATQSDQILFPKNLPTLAQMSDALIQEAMNRTANSQTAAAQMLGISQSALSRRITKEK

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=460, Percent_Identity=31.0869565217391, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1790299, Length=477, Percent_Identity=28.5115303983228, Blast_Score=182, Evalue=6e-47,
Organism=Escherichia coli, GI1790437, Length=464, Percent_Identity=29.0948275862069, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1789233, Length=312, Percent_Identity=33.0128205128205, Blast_Score=158, Evalue=7e-40,
Organism=Escherichia coli, GI87082117, Length=242, Percent_Identity=36.3636363636364, Blast_Score=157, Evalue=9e-40,
Organism=Escherichia coli, GI1787583, Length=313, Percent_Identity=30.0319488817891, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1788905, Length=409, Percent_Identity=26.4058679706601, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI1786524, Length=367, Percent_Identity=33.2425068119891, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1789087, Length=266, Percent_Identity=31.203007518797, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI87082152, Length=231, Percent_Identity=34.1991341991342, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI87081872, Length=322, Percent_Identity=28.5714285714286, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1789828, Length=236, Percent_Identity=33.4745762711864, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87081858, Length=291, Percent_Identity=25.085910652921, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51167; Mature: 51167

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLARNILLVDDEASWLRTLSITLNRLVPEAKIDTCVDSRQVMSRLQTGDYALVLLDLTM
CCCCCCEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEC
PFHSGEDLLEMIRSEFPKTRVLIVTGVNEVDTAVRCIKNGAYDYFIKTDKVDDLARTVRR
CCCCCHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHH
ALEVVGLERNYLRIKESFLSRTLSRPEVFNNILTCEPALLDQFRYLEAVALSPEPILIQG
HHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEC
ESGTGKDEFAKSCHQLICADAPFVNVNLAGIGTSAFELQLFGQLHTGEDGQISAQAGVLH
CCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEEEEEECCCCCCEEHHHHHHH
QVQSGLLYLNEIGDLPIEAQAKLVDVIEHKQYYPIGSDRAYPVLCKIITSTQHDLLALNQ
HHHHCCEEEEHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHCC
AGKFRSDLLYRLRSHTIKLPPLRQRKLDLSMLINHFISLAAKEMGLSEPQQPASLAQQLS
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
EYDFPGNLHELKGMVFDAVSRSDGIALNITPFMEAINLSKSSHATQSDQILFPKNLPTLA
HCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCCCCCCCCEECCCCCCHHH
QMSDALIQEAMNRTANSQTAAAQMLGISQSALSRRITKEK
HHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHCCCC
>Mature Secondary Structure
MKLARNILLVDDEASWLRTLSITLNRLVPEAKIDTCVDSRQVMSRLQTGDYALVLLDLTM
CCCCCCEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEC
PFHSGEDLLEMIRSEFPKTRVLIVTGVNEVDTAVRCIKNGAYDYFIKTDKVDDLARTVRR
CCCCCHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHH
ALEVVGLERNYLRIKESFLSRTLSRPEVFNNILTCEPALLDQFRYLEAVALSPEPILIQG
HHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEC
ESGTGKDEFAKSCHQLICADAPFVNVNLAGIGTSAFELQLFGQLHTGEDGQISAQAGVLH
CCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEEEEEECCCCCCEEHHHHHHH
QVQSGLLYLNEIGDLPIEAQAKLVDVIEHKQYYPIGSDRAYPVLCKIITSTQHDLLALNQ
HHHHCCEEEEHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHCC
AGKFRSDLLYRLRSHTIKLPPLRQRKLDLSMLINHFISLAAKEMGLSEPQQPASLAQQLS
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
EYDFPGNLHELKGMVFDAVSRSDGIALNITPFMEAINLSKSSHATQSDQILFPKNLPTLA
HCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCCCCCCCCEECCCCCCHHH
QMSDALIQEAMNRTANSQTAAAQMLGISQSALSRRITKEK
HHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]